Relationships between serum BDNF and the antidepressant effect of acute exercise in depressed women

Psychoneuroendocrinology

Volumn 74, Issue , 2016, Pages 286-294

  Meyer, Jacob D ^b   Koltyn, Kelli F ^b   Stegner, Aaron J ^a,b   Kim, Jee Seon ^b   Cook, Dane B ^a,b  

^a WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Antidepressant response; Brain derived neurotrophic factor; Depression; Exercise; Exercise intensity; Mood

Indexed keywords

ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; SEROTONIN ANTAGONIST; BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN;

ADULT; ANALYSIS OF VARIANCE; ANTIDEPRESSANT ACTIVITY; ARTICLE; BICYCLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXERCISE; EXERCISE INTENSITY; FEMALE; HUMAN; MAJOR DEPRESSION; MOOD; MOOD DISORDER; PRIORITY JOURNAL; PROFILE OF MOOD STATES; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; STEADY STATE; THERAPY EFFECT; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT RESPONSE; BLOOD; KINESIOTHERAPY; MIDDLE AGED; PROCEDURES; YOUNG ADULT;

ADULT; ANTIDEPRESSIVE AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSIVE DISORDER, MAJOR; EXERCISE THERAPY; FEMALE; HUMANS; MIDDLE AGED; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84988952508     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2016.09.022     Document Type: Article

References (53)

1. Beck, A.T., Steer, R.A., Ball, R., Ranieri, W.F., Comparison of beck depression inventories-IA and-II in psychiatric outpatients. J. Pers. Assess. 67 (1996), 588–597, 10.1207/s15327752jpa6703_13.
2. Borg, G., Borg's Perceived Exertion and Pain Scales. 1998, Human Kinetics, Champaign, IL,US.
3. Bromet, E., Andrade, L.H., Hwang, I., Sampson, N.A., Alonso, J., de Girolamo, G., de Graaf, R., Demyttenaere, K., Hu, C., Iwata, N., Karam, A.N., Kaur, J., Kostyuchenko, S., Lepine, J.-P., Levinson, D., Matschinger, H., Mora, M.E.M., Browne, M.O., Posada-Villa, J., Viana, M.C., Williams, D.R., Kessler, R.C., Cross-national epidemiology of DSM-IV major depressive episode. BMC Med., 9, 2011, 90, 10.1186/1741-7015-9-90.
4. Brunoni, A.R., Lopes, M., Fregni, F., A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. Int. J. Neuropsychopharmacol. 11 (2008), 1169–1180, 10.1017/S1461145708009309.
5. Castrén, E., Võikar, V., Rantamäki, T., Role of neurotrophic factors in depression. Curr. Opin. Pharmacol. 7 (2007), 18–21, 10.1016/j.coph.2006.08.009.
6. Cohen, J., Statistical Power Analysis for the Behavioral Sciences. 1988, Routledge Academic, New York, NY.
7. Cooney, G.M., Dwan, K., Greig, C.A., Lawlor, D.A., Rimer, J., Waugh, F.R., McMurdo, M., Mead, G.E., Exercise for depression. Cochrane Database Syst. Rev., 9, 2013, CD004366, 10.1002/14651858.Cd004366.pub6.
8. Cotman, C.W., Berchtold, N.C., Exercise: a behavioral intervention to enhance brain health and plasticity. Trends Neurosci. 25 (2002), 295–301.
9. Dishman, R.K., Berthoud, H.-R., Booth, F.W., Cotman, C.W., Edgerton, V.R., Fleshner, M.R., Gandevia, S.C., Gomez-Pinilla, F., Greenwood, B.N., Hillman, C.H., Kramer, A.F., Levin, B.E., Moran, T.H., Russo-Neustadt, A.A., Salamone, J.D., van Hoomissen, J.D., Wade, C.E., York, D.A., Zigmond, M.J., Neurobiology of exercise. Obesity 14 (2006), 345–356, 10.1038/oby.2006.46.
10. Dotson, V.M., Hsu, F.-C., Langaee, T.Y., McDonough, C.W., King, A.C., Cohen, R.A., Newman, A.B., Kritchevsky, S.B., Myers, V., Manini, T.M., Pahor, M., Genetic moderators of the impact of physical activity on depressive symptoms. J. Frailty Aging 5 (2016), 6–14, 10.14283/jfa.2016.76.
11. Dowlati, Y., Herrmann, N., Swardfager, W., Liu, H., Sham, L., Reim, E.K., Lanctôt, K.L., A meta-analysis of cytokines in major depression. Biol. Psychiatry 67 (2010), 446–457, 10.1016/j.biopsych.2009.09.033 Cortical Inhibitory Deficits in Depression.
12. Gómez-Pinilla, F., Ying, Z., Roy, R.R., Molteni, R., Edgerton, V.R., Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity. J. Neurophysiol. 88 (2002), 2187–2195, 10.1152/jn.00152.2002.
13. Gass, P., Hellweg, R., Peripheral brain-derived neurotrophic factor (BDNF) as a biomarker for affective disorders?. Int. J. Neuropsychopharmacol. 13 (2010), 1–4, 10.1017/S1461145709991039.
14. Groves, J.O., Is it time to reassess the BDNF hypothesis of depression?. Mol. Psychiatry 12 (2007), 1079–1088, 10.1038/sj.mp.4002075.
15. Holsboer, F., Stress, hypercortisolism and corticosteroid receptors in depression: implicatons for therapy. J. Affect. Disord. 62 (2001), 77–91, 10.1016/S0165-0327(00)00352-9 Kraepelin special issue.
16. Huang, T., Larsen, K.T., Ried-Larsen, M., Møller, N.C., Andersen, L.b., The effects of physical activity and exercise on brain-derived neurotrophic factor in healthy humans: a review. Scand. J. Med. Sci. Sports 24 (2014), 1–10, 10.1111/sms.12069.
17. Jacobs, B.L., van Praag, H., Gage, F.H., Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol. Psychiatry 5 (2000), 262–269.
18. Julian, L.J., Measures of anxiety: state-trait anxiety inventory (STAI), beck anxiety inventory (BAI), and hospital anxiety and depression scale-Anxiety (HADS-A). Arthritis Care Res. 63 (2011), S467–S472, 10.1002/acr.20561.
19. Kabacoff, R.I., Segal, D.L., Hersen, M., Van Hasselt, V.B., Psychometric properties and diagnostic utility of the beck anxiety inventory and the state-trait anxiety inventory with older adult psychiatric outpatients. J. Anxiety Disord. 11 (1997), 33–47, 10.1016/S0887-6185(96)00033-3.
20. Karege, F., Schwald, M., Cisse, M., Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neurosci. Lett. 328 (2002), 261–264, 10.1016/S0304-3940(02)00529-3.
21. Knaepen, K., Goekint, M., Heyman, E.M., Meeusen, R., Neuroplasticity-exercise-Induced response of peripheral brain-derived neurotrophic factor: a systematic review of experimental studies in human subjects. Sports Med. 40:September (1) (2010), 765–801, 10.2165/11534530-000000000-00000.
22. Laske, C., Banschbach, S., Stransky, E., Bosch, S., Straten, G., Machann, J., Fritsche, A., Hipp, A., Niess, A., Eschweiler, G.W., Exercise-induced normalization of decreased BDNF serum concentration in elderly women with remitted major depression. Int. J. Neuropsychopharmacol. 13 (2010), 595–602, 10.1017/S1461145709991234.
23. Matrisciano, F., Bonaccorso, S., Ricciardi, A., Scaccianoce, S., Panaccione, I., Wang, L., Ruberto, A., Tatarelli, R., Nicoletti, F., Girardi, P., Shelton, R.C., Changes in BDNF serum levels in patients with major depression disorder (MDD) after 6 months treatment with sertraline, escitalopram, or venlafaxine. J. Psychiatr. Res. 43 (2009), 247–254, 10.1016/j.jpsychires.2008.03.014.
24. McNair, D.M., Lorr, M., Droppleman, L.F., Profile of Mood States: Manual. 1971, Educational and Industrial Testing Services (Edits), San Diego, Calif.
25. Meyer, J.D., Ellingson, L.D., Koltyn, K.F., Stegner, A.J., Kim, J.-S., Cook, D.B., Psychobiological responses to preferred- and prescribed-intensity exercise in MDD. Med. Sci. Sports Exerc., 2016 in press.
26. Meyer, J.D., Koltyn, K.F., Stegner, A.J., Kim, J.-S., Cook, D.B., Influence of exercise intensity for improving depressed mood in depression: a dose-response study. Behav. Ther. 47 (2016), 527–537, 10.1016/j.beth.2016.04.003.
27. Mikoteit, T., Beck, J., Eckert, A., Hemmeter, U., Brand, S., Bischof, R., Holsboer-Trachsler, E., Delini-Stula, A., High baseline BDNF serum levels and early psychopathological improvement are predictive of treatment outcome in major depression. Psychopharmacology (Berl.) 231 (2014), 2955–2965, 10.1007/s00213-014-3475-8.
28. Mikoteit, T., Hemmeter, U., Eckert, A., Brand, S., Bischof, R., Delini-Stula, A., Holsboer-Trachsler, E., Beck, J., Improved alertness is associated with early increase in serum brain-derived neurotrophic factor and antidepressant treatment outcome in major depression. Neuropsychobiology, 2015, 16–28, 10.1159/000437439.
29. Molendijk, M.L., Spinhoven, P., Polak, M., Bus, B.a.A., Penninx, B.W.J.H., Elzinga, B.M., Serum BDNF concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (N = 9484). Mol. Psychiatry 19 (2014), 791–800, 10.1038/mp.2013.105.
30. Morgan, W.P., Affective beneficence of vigorous physical activity. Med. Sci. Sports Exerc. 17 (1985), 94–100, 10.1249/00005768-198502000-00015.
31. Nyenhuis, D.L., Yamamoto, C., Luchetta, T., Terrien, A., Parmentier, A., Adult and geriatric normative data and validation of the profile of mood states. J. Clin. Psychol. 55 (1999), 79–86.
32. Ogilvie, A.D., Battersby, S., Fink, G., Harmar, A.J., Goodwin, G.M., Bubb, V.J., Dale Smith, C.A., Polymorphism in serotonin transporter gene associated with susceptibility to major depression. Lancet 347 (1996), 731–733, 10.1016/S0140-6736(96)90079-3.
33. Owens, M.J., Nemeroff, C.B., Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clin. Chem. 40 (1994), 288–295.
34. Pan, W., Banks, W.A., Fasold, M.B., Bluth, J., Kastin, A.J., Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 37 (1998), 1553–1561, 10.1016/s0028-3908(98)00141-5.
35. Pluchino, N., Cubeddu, A., Begliuomini, S., Merlini, S., Giannini, A., Bucci, F., Casarosa, E., Luisi, M., Cela, V., Genazzani, A.R., Daily variation of brain-derived neurotrophic factor and cortisol in women with normal menstrual cycles, undergoing oral contraception and in postmenopause. Hum. Reprod. 24 (2009), 2303–2309, 10.1093/humrep/dep119.
36. Polyakova, M., Stuke, K., Schuemberg, K., Mueller, K., Schoenknecht, P., Schroeter, M.L., BDNF as a biomarker for successful treatment of mood disorders: a systematic & quantitative meta-analysis. J. Affect. Disord. 174 (2015), 432–440, 10.1016/j.jad.2014.11.044.
37. Rasmussen, P., Brassard, P., Adser, H., Pedersen, M.V., Leick, L., Hart, E., Secher, N.H., Pedersen, B.K., Pilegaard, H., Evidence for a release of brain-derived neurotrophic factor from the brain during exercise. Exp. Physiol. 94 (2009), 1062–1069.
38. Reddon, J.R., Marceau, R., Holden, R.R., A confirmatory evaluation of the profile of mood states: convergent and discriminant item validity. J. Psychopathol. Behav. Assess. 7 (1985), 243–259, 10.1007/BF00960756.
39. Riolo, S.A., Nguyen, T.A., Greden, J.F., King, C.A., Prevalence of depression by race/ethnicity: findings from the national health and nutrition examination survey III. Am. J. Public Health 95 (2005), 998–1000, 10.2105/AJPH.2004.047225.
40. Saucedo Marquez, C.M., Vanaudenaerde, B., Troosters, T., Wenderoth, N., High intensity interval training evokes larger serum BDNF levels compared to intense continuous exercise. J. Appl. Physiol., 2015, 10.1152/japplphysiol.00126.2015 Bethesda Md 1985 jap.00126.2015.
41. Schildkraut, J.J., The catecholamine hypothesis of affective disorders: a review of supporting evidence. Am. J. Psychiatry 122 (1965), 509–522, 10.1176/ajp.122.5.509.
42. Schmidt, H.D., Duman, R.S., Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models. Neuropsychopharmacology 35 (2010), 2378–2391, 10.1038/npp.2010.114.
43. Schmolesky, M.T., Webb, D.L., Hansen, R.A., The effects of aerobic exercise intensity and duration on levels of brain-derived neurotrophic factor in healthy men. J. Sports Sci. Med. 12 (2013), 502–511.
44. Serra-Millàs, M., Are the changes in the peripheral brain-derived neurotrophic factor levels due to platelet activation?. World J. Psychiatry 6 (2016), 84–101, 10.5498/wjp.v6.i1.84.
45. Sheehan, D.V., Lecrubier, Y., Sheehan, K.H., Amorim, P., Janavs, J., Weiller, E., Hergueta, T., Baker, R., Dunbar, G.C., The mini-international neuropsychiatric interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry, 59(Suppl. 20), 1998 22-33-57.
46. Spielberger, C., Manual for the State-Trait Anxiety Inventory. 1983, Counseling Psychologists Press, Palo Alto, CA.
47. Szuhany, K.L., Bugatti, M., Otto, M.W., A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor. J. Psychiatr. Res. 60 (2015), 56–64, 10.1016/j.jpsychires.2014.10.003.
48. Takada, S., Kinugawa, S., Matsushima, S., Yokota, T., Mizushima, W., Furihata, T., Matsumoto, J., Tsuda, M., Fukushima, A., Okita, K., Tsutsui, H., Abstract 17415: recombinant human BDNF can mimic effects of exercise training in mice. Circulation, 132, 2015, A17415.
49. Toups, M.S.P., Greer, T.L., Kurian, B.T., Grannemann, B.D., Carmody, T.J., Huebinger, R., Rethorst, C., Trivedi, M.H., Effects of serum brain derived neurotrophic factor on exercise augmentation treatment of depression. J. Psychiatr. Res. 45 (2011), 1301–1306, 10.1016/j.jpsychires.2011.05.002.
50. Troiano, R.P., Berrigan, D., Dodd, K.W., MâSse, L.C., Tilert, T., Mcdowell, M., Physical activity in the United States measured by accelerometer. Med. Sci. Sports Exerc. 40 (2008), 181–188, 10.1249/mss.0b013e31815a51b3.
51. Wegner, M., Helmich, I., Machado, S., Nardi, A.E., Arias-Carrion, O., Budde, H., Effects of exercise on anxiety and depression disorders: review of meta- analyses and neurobiological mechanisms. CNS Neurol. Disord. Drug Targets 13 (2014), 1002–1014.
52. Yarrow, J.F., White, L.J., McCoy, S.C., Borst, S.E., Training augments resistance exercise induced elevation of circulating brain derived neurotrophic factor (BDNF). Neurosci. Lett. 479 (2010), 161–165, 10.1016/j.neulet.2010.05.058.
53. Yeung, R.R., The acute effects of exercise on mood state. J. Psychosom. Res. 40 (1996), 123–141.