Exercise-induced normalization of decreased BDNF serum concentration in elderly women with remitted major depression

International Journal of Neuropsychopharmacology

Volumn 13, Issue 5, 2010, Pages 595-602

  Laske, Christoph ^a   Banschbach, Sabine ^a   Stransky, Elke ^a   Bosch, Sabine ^a   Straten, Guido ^a,b   MacHann, Jrgen ^b   Fritsche, Andreas ^b   Hipp, Arno ^b   Niess, Andreas ^b   Eschweiler, Gerhard W ^a,b  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Brain derived neurotrophic factor; Exercise; Major depression; Physical activity; Women

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

AGED; ARTICLE; CLINICAL ARTICLE; DISEASE ASSOCIATION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ERGOMETRY; EXERCISE; FEMALE; GENE EXPRESSION REGULATION; HUMAN; MAJOR DEPRESSION; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REMISSION; SPIROMETRY;

AGED; BIOLOGICAL MARKERS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSIVE DISORDER, MAJOR; EXERCISE; EXERCISE TEST; FEMALE; HUMANS; MIDDLE AGED; RECOMBINANT PROTEINS; RECURRENCE;

EID: 77953536970     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145709991234     Document Type: Article

References (40)

1. Angelucci F, Mathe AA, Aloe L (2004). Neurotrophic factors and CNS disorders: findings in rodent models of depression and schizophrenia. Progress in Brain Research 146, 151-165.
2. Aydemir O, Deveci A, Taneli F (2005). The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: a preliminary study. Progress in Neuropsychopharmacol and Biological Psychiatry 29, 261-265.
3. Babyak M, Blumenthal JA, Herman S, Khatri P, et al. (2000). Exercise treatment for major depression: maintenance of therapeutic benefit at 10 months. Psychosomatic Medicine 62, 633-638.
4. Berton O, Nestler EJ (2006). New approaches to antidepressant drug discovery: beyond monoamines. Nature Reviews Neuroscience 7, 137-151.
5. Blumenthal JA, Babyak MA, Doraiswamy PM, Watkins L, et al. (2007). Exercise and pharmacotherapy in the treatment of major depressive disorder. Psychosomatic Medicine 69, 587-596.
6. Blumenthal JA, Babyak MA, Moore KA, Craighead WE, et al. (1999). Effects of exercise training on older patients with major depression. Archives of Internal Medicine 159, 2349-2356.
7. Borg G (1970). Perceived exertion as an indicator of somatic stress. Scandinavian Journal of Rehabilitation Medicine 2, 92-98.
8. Brunoni AR, Lopes M, Fregni F (2008). A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. International Journal of Neuropsychopharmacology 11, 1169-1180.
9. Dunn AL, Trivedi MH, Kampert JB, Clark CG, et al. (2005). Exercise treatment for depression: efficacy and dose response. American Journal of Preventive Medicine 28, 1-8.
10. Ferris LT, Williams JS, Shen CL (2007). The effect of acute exercise on serum brain-derived neurotrophic factor levels and cognitive function. Medicine & Science in Sports & Exercise 39, 728-734.
11. Flöel A, Ruscheweyh R, Krüger K, Willemer C, et al. (2009). Physical activity and memory functions: are neurotrophins and cerebral gray matter volume the missing link? Neuroimage. Published online: 21 October 2009. doi:10.1016/j.neuroimage.2009.10.043.
12. Fujimura H, Altar CA, Chen R, Nakamura T, et al. (2002). Brain-derived neurotrophic factor is stored in human platelets and released by agonist stimulation. Thrombosis and Haemostasis 87, 728-734.
13. Gold SM, Schulz KH, Hartmann S, Mladek M, et al. (2003). Basal serum levels and reactivity of nerve growth factor and brain-derived neurotrophic factor to standardized acute exercise in multiple sclerosis and controls. Journal of Neuroimmunology 138, 99-105.
14. Goodwin RD (2003). Association between physical activity and mental disorders among adults in the United States. Preventive Medicine 36, 698-703.
15. Griffin EW, Bechara RG, Birch AM, Kelly AM (2009). Exercise enhances hippocampal-dependent learning in the rat: evidence for a BDNF-related mechanism. Hippocampus 19, 973-980.
16. Gustafsson G, Lira CM, Johansson J, Wisén A, et al. (2009). The acute response of plasma brain-derived neurotrophic factor as a result of exercise in major depressive disorder. Psychiatry Research 169, 244-248.
17. Hashimoto K, Shimizu E, Iyo M (2004). Critical role of brain-derived neurotrophic factor in mood disorders. Brain Research. Brain Research Reviews 45, 104-114.
18. Hilberg T, Menzel K, Gläser D, Zimmermann S, et al. (2008). Exercise intensity: platelet function and platelet-leukocyte conjugate formation in untrained subjects. Thrombosis Research 122, 77-84.
19. Kamphuis MA, Geerlings MI, Tijhuis MA, Giampaoli S, et al. (2007). Physical inactivity, depression, and risk of cardiovascular mortality. Medicine and Science in Sports and Exercise 39, 1693-1699.
20. Karege F, Perret G, Bondolfi G, Schwald M, et al. (2002). Decreased serum brain-derived neurotrophic factor levels in major depressed patients. Psychiatry Research 109, 143-148.
21. Kovalchuk Y, Hanse E, Kafitz KW, Konnerth A (2002). Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation. Science 295(5560), 1729-1734.
22. Laske C, Eschweiler GW (2006). Brain-derived neurotrophic factor (BDNF): from nerve growth factor to modulator of brain plasticity in cognitive processes and psychiatric diseases [in German]. Nervenarzt 77, 523-537.
23. Laske C, Stransky E, Leyhe T, Eschweiler GW, et al. (2006). Decreased brain-derived neurotrophic factor (BDNF) and b-thromboglobulin (b-TG) blood levels in Alzheimer's disease. Thrombosis and Haemostasis 96, 102-103.
24. Malberg JE, Eisch AJ, Nestler EJ, Duman RS (2000). Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. Journal of Neuroscience 20, 9104-9110.
25. Matrisciano F, Bonaccorso S, Ricciardi A, Scaccianoce S, et al. (2009). Changes in BDNF serum levels in patients with major depression disorder (MDD) after 6 months treatment with sertraline, escitalopram, or venlafaxine. Journal of Psychiatric Research 43, 247-254.
26. Matthews VB, Aström MB, Chan MH, Bruce CR, et al. (2009). Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase. Diabetologia 52, 1409-1418.
27. Pan W, Banks WA, Fasold MB, Bluth J, et al. (1998). Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 37, 1553-1561.
28. Poduslo JF, Curran GL (1996). Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Brain Research Molecular Brain Research 36, 280-286.
29. Porszasz J, Casaburi R, Somfay A, Woodhouse LJ, et al. (2003). Whipp BJ. A treadmill ramp protocol using simultaneous changes in speed and grade. Medicine & Science in Sports & Exercise 35, 1596-1603.
30. Roecker K, Schotte O, Niess AM, Horstmann T, et al. (1998). Predicting competition performance in long-distance running by means of a treadmill test. Medicine & Science in Sports and Exercise 30, 1552-1557.
31. Sen S, Duman R, Sanacora G (2008). Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biological Psychiatry 64, 527-532.
32. Shimizu E, Hashimoto K, Iyo M (2004). Major depressive disorders and BDNF (brain-derived neurotrophic factor). Nihon Shinkei Seishin Yakurigaku Zasshi 24, 147-150. (Pubitemid 38980844)
33. Shimizu E, Hashimoto K, Okamura N, Koike K, et al. (2003). Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biological Psychiatry 54, 70-75. (Pubitemid 36776725)
34. Strawbridge WJ, Deleger S, Roberts RE, Kaplan GA (2002). Physical activity reduces the risk of subsequent depression for older adults. American Journal of Epidemiology 156, 328-334.
35. Ströhle A, Stoy M, Graetz B, Scheel M, et al. (2009). Acute exercise ameliorates reduced brain-derived neurotrophic factor in patients with panic disorder. Psychoneuro-endocrinology. Published online: 13 August 2009. doi:10.1016/j.psyneuen.2009.07.013.
36. Tang SW, Chu E, Hui T, Helmeste D, et al. (2008). Influence of exercise on serum brain-derived neurotrophic factor concentrations in healthy human subjects. Neuroscience Letters 431, 62-65.
37. Van Praag H, Kempermann G, Gage F (1999). Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nature Neuroscience 2, 266-270.
38. Yoshimura R, Mitoma M, Sugita A, Hori H, et al. (2007). Effects of paroxetine or milnacipran on serum brain-derived neurotrophic factor in depressed patients. Progress in Neuropsychopharmacology and Biological Psychiatry 31, 1034-1037.
39. Zanardini R, Gazzoli A, Ventriglia M, Perez J, et al. (2006). Effect of repetitive transcranial magnetic stimulation on serum brain derived neurotrophic factor in drug resistant depressed patients. Journal of Affective Disorders 91, 83-86. (Pubitemid 43254643)
40. Zoladz JA, Pilc A, Majerczak J, Grandys M, et al. (2008). Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men. Journal of Physiology and Pharmacology 59 (Suppl. 7), 119-132.