Cancer-associated fibroblasts in pancreatic cancer are reprogrammed by tumor-induced alterations in genomic DNA methylation

Cancer Research

Volumn 76, Issue 18, 2016, Pages 5395-5404

  Xiao, Qian ^a,b,c   Zhou, Donger ^a,b,c   Rucki, Agnieszka A ^b,c   Williams, Jamila ^b,c   Zhou, Jiaojiao ^a,b,c   Mo, Guanglan ^b,c   Murphy, Adrian ^b,c   Fujiwara, Kenji ^b,c   Kleponis, Jennifer ^b,c   Salman, Bulent ^b,c   Wolfgang, Christopher L ^b,c   Anders, Robert A ^b,c   Zheng, Shu ^a   Jaffee, Elizabeth M ^b,c   Zheng, Lei ^b,c  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DECITABINE; DNA METHYLTRANSFERASE 1; GENOMIC DNA; SOMATOMEDIN C; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER ASSOCIATED FIBROBLAST; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CONTROLLED STUDY; DNA METHYLATION; DNMT1 GENE; DOWN REGULATION; GENE ACTIVATION; GENE EXPRESSION PROFILING; GENE SEQUENCE; HUMAN; HUMAN CELL; IGF1 GENE; IN VIVO STUDY; LIMIT OF QUANTITATION; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; SOCS1 GENE; TUMOR MICROENVIRONMENT; ANIMAL; DNA MICROARRAY; GENETICS; NONOBESE DIABETIC MOUSE; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; POLYMERASE CHAIN REACTION; SCID MOUSE; XENOGRAFT;

ANIMALS; CANCER-ASSOCIATED FIBROBLASTS; CARCINOMA, PANCREATIC DUCTAL; DNA METHYLATION; HETEROGRAFTS; HUMANS; MICE; MICE, INBRED NOD; MICE, SCID; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PANCREATIC NEOPLASMS; POLYMERASE CHAIN REACTION; SUPPRESSOR OF CYTOKINE SIGNALING 1 PROTEIN; TUMOR MICROENVIRONMENT;

EID: 84988942467     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-3264     Document Type: Article

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