Pooled sequencing and rare variant association tests for identifying the determinants of emerging drug resistance in malaria parasites

Molecular Biology and Evolution

Volumn 32, Issue 4, 2015, Pages 1080-1090

  Cheeseman, Ian H ^a   McDew White, Marina ^a   Phyo, Aung Pyae ^b   Sriprawat, Kanlaya ^b   Nosten, Francois ^b,c   Anderson, Timothy J C ^a  

^a SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

^b MAHIDOL UNIVERSITY   (Thailand)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

drug resistance; malaria; pooled sequencing; rare variants

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISININ; ARTEMISININ DERIVATIVE;

ANTIMALARIAL DRUG RESISTANCE; ARTICLE; EFFECTIVE POPULATION SIZE; GENE FREQUENCY; GENE LOCUS; GENE MAPPING; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MALARIA; MUTATION RATE; NONHUMAN; PHENOTYPE; PLASMODIUM; PLASMODIUM FALCIPARUM; SELECTIVE SWEEP; SINGLE NUCLEOTIDE POLYMORPHISM; DNA SEQUENCE; DRUG EFFECTS; DRUG RESISTANCE; GENETIC ASSOCIATION STUDY; GENETICS; GENOME; MALARIA FALCIPARUM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PARASITOLOGY; PROCEDURES;

ANTIMALARIALS; ARTEMISININS; BASE SEQUENCE; DRUG RESISTANCE; GENETIC ASSOCIATION STUDIES; GENOME; HUMANS; MALARIA, FALCIPARUM; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA;

EID: 84988299737     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msu397     Document Type: Article

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