Malaria Burden and Artemisinin Resistance in the Mobile and Migrant Population on the Thai-Myanmar Border, 1999-2011: An Observational Study

PLoS Medicine

Volumn 10, Issue 3, 2013, Pages

  Carrara, Verena I ^a,b   Lwin, Khin Maung ^a,b   Phyo, Aung Pyae ^a,b   Ashley, Elizabeth ^a,b,c   Wiladphaingern, Jacher ^a   Sriprawat, Kanlaya ^a   Rijken, Marcus ^a,d   Boel, Machteld ^a,e   McGready, Rose ^a,b,c   Proux, Stephane ^a   Chu, Cindy ^a,b,c   Singhasivanon, Pratap ^f   White, Nicholas ^b,c   Nosten, François ^a,b,c  

^a SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^b MAHIDOL OXFORD TROPICAL MEDICINE RESEARCH UNIT   (Thailand)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

^f MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMISININ; ARTESUNATE; ARTESUNATE PLUS MEFLOQUINE; DIHYDROARTEMISININ; MEFLOQUINE;

ADOLESCENT; ADULT; ARTICLE; CHILD; DIAGNOSTIC TEST ACCURACY STUDY; DRUG EFFICACY; FATALITY; FEMALE; GAMETOCYTE; HEALTH CARE PERSONNEL; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALARIA; MALE; MICROSCOPY; MIGRANT WORKER; MONITORING; MYANMAR; OBSERVATIONAL STUDY; PARASITE TRANSMISSION; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; POLYMERASE CHAIN REACTION; PREGNANCY; PRESCHOOL CHILD; QUALITY CONTROL; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY; THAILAND;

ANTIMALARIALS; ARTEMISININS; CLIMATE; COMMUNITY HEALTH WORKERS; CROSS-SECTIONAL STUDIES; DRUG RESISTANCE; FEMALE; GEOGRAPHY; HOSPITALIZATION; HUMANS; MALARIA; MEFLOQUINE; MYANMAR; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC; PREVALENCE; RAIN; REPRODUCIBILITY OF RESULTS; TEMPERATURE; THAILAND; TRANSIENTS AND MIGRANTS;

EID: 84875419985     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1001398     Document Type: Article

References (28)

1. World Health Organization (2011) World malaria report 2011. Geneva: World Health Organization.
2. Hay SI, Guerra CA, Tatem AJ, Noor AM, Snow RW, (2004) The global distribution and population at risk of malaria: past, present, and future. Lancet Infect Dis 4: 327-336.
3. Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, et al. (2009) Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med 361: 455-467.
4. Phyo AP, Nkhoma S, Stepniewska K, Ashley EA, Nair S, et al. (2012) Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study. Lancet 379: 1960-1966.
5. Korenromp EL, Williams BG, Gouws E, Dye C, Snow RW, (2003) Measurement of trends in childhood malaria mortality in Africa: an assessment of progress toward targets based on verbal autopsy. Lancet Infect Dis 3: 349-358.
6. Marsh K, (1998) Malaria disaster in Africa. Lancet 352: 924.
7. Dondorp A, Nosten F, Stepniewska K, Day N, White N, (2005) Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial. Lancet 366: 717-725.
8. Dondorp AM, Fanello CI, Hendriksen IC, Gomes E, Seni A, et al. (2010) Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Lancet 376: 1647-1657.
9. Nosten F, van Vugt M, Price R, Luxemburger C, Thway KL, et al. (2000) Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand: a prospective study. Lancet 356: 297-302.
10. Carrara VI, Sirilak S, Thonglairuam J, Rojanawatsirivet C, Proux S, et al. (2006) Deployment of early diagnosis and mefloquine-artesunate treatment of falciparum malaria in Thailand: the Tak Malaria Initiative. PLoS Med 3: e183 doi:10.1371/journal.pmed.0030183.
11. Verdrager J, (1986) Epidemiology of the emergence and spread of drug-resistant falciparum malaria in South-East Asia and Australasia. J Trop Med Hyg 89: 277-289.
12. Decludt B, Pecoul B, Biberson P, Lang R, Imivithaya S, (1991) Malaria surveillance among the displaced Karen population in Thailand April 1984 to February 1989, Mae Sot, Thailand. Southeast Asian J Trop Med Public Health 22: 504-508.
13. Brockman A, Paul RE, Anderson TJ, Hackford I, Phaiphun L, et al. (1999) Application of genetic markers to the identification of recrudescent Plasmodium falciparum infections on the northwestern border of Thailand. Am J Trop Med Hyg 60: 14-21.
14. Delacollette C, D'Souza C, Christophel E, Thimasarn K, Abdur R, et al. (2009) Malaria trends and challenges in the Greater Mekong Subregion. Southeast Asian J Trop Med Public Health 40: 674-691.
15. Barnes KI, Durrheim DN, Little F, Jackson A, Mehta U, et al. (2005) Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu-Natal, South Africa. PLoS Med 2: e330 doi:10.1371/journal.pmed.0020330.
16. White NJ, (1999) Delaying antimalarial drug resistance with combination chemotherapy. Parassitologia 41: 301-308.
17. Dolan G, ter Kuile F, Jacoutot V, White NJ, Luxemburger C, et al. (1993) Bed nets for the prevention of malaria and anaemia in pregnancy. Trans R Soc Trop Med Hyg 87: 620-626.
18. Looareesuwan S, White NJ, Chittamas S, Bunnag D, Harinasuta T, (1987) High rate of Plasmodium vivax relapse following treatment of falciparum malaria in Thailand. Lancet 2: 1052-1055.
19. White N, (2011) Determinants of relapse periodicity in Plasmodium vivax malaria. Malar J 10: 297.
20. Cheeseman IH, Miller BA, Nair S, Nkhoma S, Tan A, et al. (2012) A major genome region underlying artemisinin resistance in malaria. Science 336: 79-82.
21. Kyle DE, Webster HK (1996) Postantibiotic effect of quinine and dihydroartemisinin derivatives on Plasmodium falciparum in vitro: implications for a mechanism of recrudescence [abstract]. XIVth International Congress for Tropical Medicine and Malaria; 17-22 November 1996; Nagasaki, Japan.
22. Teuscher F, Gatton ML, Chen N, Peters J, Kyle DE, et al. (2010) Artemisinin-induced dormancy in plasmodium falciparum: duration, recovery rates, and implications in treatment failure. J Infect Dis 202: 1362-1368.
23. Saralamba S, Pan-Ngum W, Maude RJ, Lee SJ, Tarning J, et al. (2011) Intrahost modeling of artemisinin resistance in Plasmodium falciparum. Proc Natl Acad Sci U S A 108: 397-402.
24. Mok S, Imwong M, Mackinnon M, Sim J, Ramaodoss R, et al. (2011) Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription. BMC Genomics 12: 391.
25. Nosten F, (2010) Waking the sleeping beauty. J Infect Dis 202: 1300-1301.
26. Cheng Q, Kyle DE, Gatton ML, (2012) Artemisinin resistance in Plasmodium falciparum: a process linked to dormancy? Int J Parasitol Drugs Drug Resist 2: 249-255.
27. Phyo AP, Lwin KM, Price RN, Ashley EA, Russell B, et al. (2011) Dihydroartemisinin-piperaquine versus chloroquine in the treatment of Plasmodium vivax malaria in Thailand: a randomized controlled trial. Clin Infect Dis 53: 977-984.
28. Douglas NM, Anstey NM, Angus BJ, Nosten F, Price RN, (2010) Artemisinin combination therapy for vivax malaria. Lancet Infect Dis 10: 405-416.