Deficiency in the voltage-gated proton channel Hv1 increases M2 polarization of microglia and attenuates brain damage from photothrombotic ischemic stroke

Journal of Neurochemistry

Volumn 139, Issue 1, 2016, Pages 96-105

  Tian, Dai Shi ^a   Li, Chun Yu ^a   Qin, Chuan ^a   Murugan, Madhuvika ^b   Wu, Long Jun ^b   Liu, Jun Li ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

ischemic stroke; microglia; photothrombosis; polarization; voltage gated proton channel Hv1

Indexed keywords

CELL PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VOLTAGE GATED PROTON CHANNEL HV1; ANTIMETABOLITE; BROXURIDINE; CYBB PROTEIN, MOUSE; HV1 PROTON CHANNEL, MOUSE; ION CHANNEL; MEMBRANE PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; BRAIN DAMAGE; BRAIN INFARCTION; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PROTECTION; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; MALE; MICROGLIA; MOTOR COORDINATION; MOTOR DYSFUNCTION; MOUSE; NERVE CELL LESION; NEUROMODULATION; NEWBORN; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL POLARITY; CEREBROVASCULAR ACCIDENT; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PATHOLOGY; PRIMARY CELL CULTURE;

ANIMALS; ANTIMETABOLITES; BRAIN INFARCTION; BRAIN ISCHEMIA; BROMODEOXYURIDINE; CELL POLARITY; INTRACRANIAL THROMBOSIS; ION CHANNELS; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NADPH OXIDASE; NEURONS; PHENOTYPE; PRIMARY CELL CULTURE; REACTIVE OXYGEN SPECIES; STROKE;

EID: 84988025827     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13751     Document Type: Article

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