Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Latta, Clare H ^a,c   Sudduth, Tiffany L ^a   Weekman, Erica M ^a,b   Brothers, Holly M ^a   Abner, Erin L ^a   Popa, Gabriel J ^b   Mendenhall, Michael D ^b   Gonzalez Oregon, Floracita ^a,b   Braun, Kaitlyn ^a,b   Wilcock, Donna M ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Alzheimer's disease; Beta amyloid; Inflammation; Microglia

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CYTOKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 4; PRESENILIN 1; PSEN1 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL ACTIVITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FRONTAL CORTEX; HIPPOCAMPUS; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNOPHENOTYPING; IN VITRO STUDY; IN VIVO STUDY; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; ENCEPHALITIS; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; GENETICS; HUMAN; METABOLISM; MUTATION; PATHOLOGY; TIME FACTOR; TRANSFORMED CELL LINE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE, TRANSFORMED; CYTOKINES; DISEASE MODELS, ANIMAL; ENCEPHALITIS; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; GREEN FLUORESCENT PROTEINS; HUMANS; INTERLEUKIN-4; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; MUTATION; PRESENILIN-1; TIME FACTORS; TRANSDUCTION, GENETIC;

EID: 84928712938     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0243-6     Document Type: Article

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