Inhibition of NOX2 reduces locomotor impairment, inflammation, and oxidative stress after spinal cord injury

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Khayrullina, Guzal ^a   Bermudez, Sara ^a   Byrnes, Kimberly R ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Inflammation; Microglia; NOX2; Oxidative stress; Polarization; Spinal cord injury

Indexed keywords

OXIDOREDUCTASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SCRAMBLED DS TAT; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; AIF1 PROTEIN, MOUSE; CALCIUM BINDING PROTEIN; CYBB PROTEIN, MOUSE; GLYCOPROTEIN; GP91DS-TAT PROTEIN, CHIMERIC; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATORY CELL; LOCOMOTION; MACROPHAGE; MALE; MICROGLIA; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; SPINAL CORD INJURY; WESTERN BLOTTING; ANALYSIS OF VARIANCE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; METABOLISM; MOVEMENT DISORDERS; PHYSIOLOGY; TIME FACTOR;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD; CALCIUM-BINDING PROTEINS; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; GLYCOPROTEINS; INFLAMMATION; MACROPHAGES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICROFILAMENT PROTEINS; MICROGLIA; MOVEMENT DISORDERS; NADPH OXIDASE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SPINAL CORD INJURIES; TIME FACTORS;

EID: 84941773774     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0391-8     Document Type: Article

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