Atractylone, an active constituent of KMP6, attenuates allergic inflammation on allergic rhinitis in vitro and in vivo models

Molecular Immunology

Volumn 78, Issue , 2016, Pages 121-132

  Kim, Hee Yun ^a   Nam, Sun Young ^a   Hwang, Sung Yeoun ^b   Kim, Hyung Min ^a   Jeong, Hyun Ja ^c  

^a Kyung Hee University   (South Korea)

^b Korea Bio Medical Science Institute   (South Korea)

^c Hoseo University   (South Korea)

Author keywords

Allergic rhinitis; Atractylone; Caspase 1; Mast cells; Proinflammatory cytokine; Thymic stromal lymphopoietin

Indexed keywords

ANTIALLERGIC AGENT; ANTIINFLAMMATORY AGENT; ATRACTYLONE; BIOLOGICAL MARKER; CYCLOOXYGENASE 2; DEXAMETHASONE; HISTAMINE; I KAPPA B ALPHA; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; KMP 6; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN D2; THYMIC STROMAL LYMPHOPOIETIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ATRACTYLON; PLANT EXTRACT; PYEONGWEE-SAN EXTRACT; SESQUITERPENE;

ALLERGIC RHINITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INVASION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME ACTIVATION; EOSINOPHIL; FEMALE; HISTAMINE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; INTRACELLULAR SIGNALING; KOREAN MEDICINE; LEUKOCYTE MIGRATION; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TH1 TH2 BALANCE; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; DISEASE MODEL; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INFLAMMATION; LIQUID CHROMATOGRAPHY; MAST CELL; NOSE MUCOSA; REAL TIME POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MAST CELLS; MICE; MICE, INBRED BALB C; NASAL MUCOSA; PLANT EXTRACTS; REAL-TIME POLYMERASE CHAIN REACTION; RHINITIS, ALLERGIC; SESQUITERPENES; TANDEM MASS SPECTROMETRY;

EID: 84987971666     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2016.09.007     Document Type: Article

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