Peroxisome proliferator-activated receptor γ negativety regulated allergic rhinitis in mice

Allergology International

Volumn 58, Issue 2, 2009, Pages 247-253

  Fukui, Naoko ^a   Honda, Kohei ^a   Ito, Eiko ^a   Ishikawa, Kazuo ^a  

^a AKITA UNIVERSITY   (Japan)

Author keywords

Allergic rhinitis; Eosinophils; Murine model; Ovalbumin

Indexed keywords

CIGLITAZONE; IMMUNOGLOBULIN E; INTERLEUKIN 5; OVALBUMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ALLERGIC REACTION; ALLERGIC RHINITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; EOSINOPHIL; EPITHELIUM CELL; FEMALE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; NOSE MUCOSA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BEHAVIOR, ANIMAL; EOSINOPHILS; EPITHELIAL CELLS; FEMALE; HISTAMINE; IMMUNOGLOBULIN E; INTERFERON-GAMMA; INTERLEUKIN-13; INTERLEUKIN-5; MICE; MICE, INBRED BALB C; NASAL MUCOSA; OVALBUMIN; PPAR GAMMA; RHINITIS, ALLERGIC, PERENNIAL; SNEEZING; SPLEEN; THIAZOLIDINEDIONES;

EID: 67651148388     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.08-OA-0047     Document Type: Article

References (24)

1. Togias A. Rhinitis and asthma: Evidence for respiratory system integration. J Allergy Clin Immunol 1993;111: 1171-83.
2. Laynaert B, Bousquet J, Neukirch C, Liard R, Neukirch F. Perennial rhinitis: An independent risk factor for asthma in nonatopic subjects: result from the European Community Respiratory Health Survey. J Allergy Clin Immunol 1995;104:301-4.
3. Varney VA, Jacobson MR, Sudderick RM et al. Immunohistology of the nasal mucosa following allergen-induced rhinitis. Identification of activated T lymphocytes, eosinophils, and neutrophils. Am Res Respir Dis 1992;146:170-6.
4. Kohi F, Miyagawa H, Agraswal DK, Bewtra AK, Townley RG. Generation of leukotriene B4 and C4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects. Ann Allergy 1990; 65:228-32.
5. Frigas E, Leogering DA, Solley GO, Farrow GM, Gleich GJ. Elevated levels of the eosinophil granule major basic protein in the sputum of patients with bronchial asthma. Mayo Clin Proc 1981;56:345-53.
6. Spiegelman BM. PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. Diabetes 1998;47:507-14.
7. Willson TM, Cobb JE, Cowan DJ et al. The structure-activity relationship between peroxisome proliferator- activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem 1996;39: 665-8.
8. Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 1995;83:803-12.
9. Clark RB, Bishop-Bailey D, Estrada-Hernandez T, Hla T, Puddington L, Padula SJ. The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses. J Immunol 2000; 164:1364-71.
10. Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferators-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998; 391:79-82.
11. Angeli V, Hammad H, Staels B, Capron M, Lambrecht BN, Trottein F. Peroxisome proliferator-activated receptor gamma inhibits the migration of dendritic cells: consequences for the immune response. J Immunol 2003;170: 5295-301.
12. Sugiyama H, Nonaka T, Kishimoto T, Komoriya K, Tsuji K, Nakahata T. Peroxisome proliferator-activated receptors are expressed in human cultured mast cells: a possible role of these receptors in negative regulation of mast cell activation. Eur J Immunol 2000; 30:3363-70.
13. Woerly G, Honda K, Loyens M et al. Peroxisome proliferator-activated receptors alpha and gamma down-regulate allergic inflammation and eosinophil activation. J Exp Med 2003; 198:411-21.
14. Ueki S, Adachi T, Bourdeaux J et al. Expression of PPAR-gamma in eosinophils and its functional role in survival and chemotaxis. Immunol Lett 2003;86:183-9.
15. Trifilieff A, Bench A, Hanley M, Bayley D, Campbell E, Whittaker P. PPAR-alpha and -gamma but not -delta agonists inhibit airway inflammation in a murine model of asthma: in vitro evidence for an NF-kappa-B-independent effect. Br J Pharmacol 2003; 139:163-71.
16. Honda K, Marquillies P, Capron M, Dombrowicz D. Peroxisome proliferator-activated receptor gamma is expressed in airways and inhibits features of airway remodeling in a mouse asthma model. J Allergy Clin Immunol 2004;113:882-8.
17. Jeffery PK, Haahtela T. Allergic rhinitis and asthma: inflammation in a one-airway condition. BMC Pulm Med 2006;6 (Suppl 1) :1-12.
18. Fujimura Y, Tachibana H, Yamada K. Peroxisome proliferator-activated receptor ligands negatively regulate the expression of the high-affinity IgE receptor Fc epsilon RI in human basophilic KU812 cells. Biochem Biophys Res Commun 2002;297:193-201.
19. Kobayashi Y, Ueki S, Mahemuti G et al. Physiological levels of 15-deoxy-Delta 12, 14-prostaglandin J2 prime eotaxin-induced chemotaxis on human eosinophils through peroxisome proliferator-activated receptor-gamma ligation. J Immunol 2005;175:5744-50.
20. 2 receptor CRTH2: structure, properties, and functions in leukocytes. Prostaglandins Leukot Essent Fatt Acids 2003;69:169-77.
21. Angela CCW, Xinhua D, Bao L, Douglas JC. Peroxisome proliferators-activated receptor-γ regulates airway epithelial cell activation. Am J Respir Cell Mol Biol 2001;24:688-93.
22. Benayoun L, Letuve S, Druilhe A et al. Regulation of peroxisome proliferators-activated receptor gamma expression in human asthmatic airways: relationship with proliferation, apotosis, and airway remodeling. Am J Respir Crit Care Med 2001;164:1487-94.
23. Kang HJ, Cinn YG, Hwang SJ et al. Up-regulation of peroxisome proliferators-activated γ receptor in perennial allergic rhinitis. Arch Otolaryngol Head Neck Surg 2006; 132:1196-200.
24. Cardell LO, Hägge M, Uddman R, Adner M. Downregulation of peroxisome proliferator-activated receptors (PPARs) in nasal polyposis. Respir Res 2005;6:132-9.