Effects of pomegranate juice consumption on oxidative stress in patients with type 2 diabetes: a single-blind, randomized clinical trial

International Journal of Food Sciences and Nutrition

Volumn 68, Issue 2, 2017, Pages 249-255

  Sohrab, Golbon ^a   Ebrahimof, Samira ^a   Sotoudeh, Giti ^b   Neyestani, Tirang Reza ^a   Angoorani, Pooneh ^a   Hedayati, Mehdi ^c   Siasi, Fereidoun ^b  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

cardiovascular disease; diabetes; oxidative stress; Pomegranate juice

Indexed keywords

ANTIOXIDANT; ARYLDIALKYLPHOSPHATASE; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PON1 PROTEIN, HUMAN;

ADULT; AGED; BLOOD; BODY MASS; CALORIC INTAKE; CHEMISTRY; CONTROLLED STUDY; DIET THERAPY; FEMALE; FRUIT; FRUIT AND VEGETABLE JUICE; GENETICS; HUMAN; LYTHRACEAE; MALE; METABOLISM; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; NUTRITIONAL ASSESSMENT; OXIDATIVE STRESS; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE;

ADULT; AGED; ANTIOXIDANTS; ARYLDIALKYLPHOSPHATASE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; ENERGY INTAKE; FEMALE; FRUIT; FRUIT AND VEGETABLE JUICES; HUMANS; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; NUTRITION ASSESSMENT; OXIDATIVE STRESS; PUNICACEAE; SINGLE-BLIND METHOD;

EID: 84987879257     PISSN: 09637486     EISSN: 14653478     Source Type: Journal    
DOI: 10.1080/09637486.2016.1229760     Document Type: Article

References (38)

1. Al-Jarallah A, Igdoura F, Zhang Y, Tenedero CB, White EJ, MacDonald ME, Igdoura SA, Trigatti BL., 2013. The effect of pomegranate extract on coronary artery atherosclerosis in SR-BI/APOE double knockout mice. Atherosclerosis. 228:80–89.
2. Aviram M, Dornfeld L, Rosenblat M, Volkova N, Kaplan M, Coleman R, Hayek T, Presser D, Fuhrman B., 2000. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation:studies in humans and in atherosclerotic apolipoprotein E-deficient mice. Am J Clin Nutr. 71:1062–1076.
3. Aviram M, Dornfeld L, Kaplan M, Coleman R, Gaitini D, Nitecki S, Hofman A, Rosenblat M, Volkova N, Presser D, et al. 2002. Pomegranate juice flavonoids inhibit low-density lipoprotein oxidation and cardiovascular diseases:studies in atherosclerotic mice and in humans. Drugs Exp Clin Res. 28:49–62.
4. Aviram M, Rosenblat M, Gaitini D, Nitecki S, Hoffman A, Dornfeld L, Volkova N, Presser D, Attias J, Liker H, et al. 2004. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Clin Nutr. 23:423–433.
5. Aviram M, Rosenblat M., 2004. 2004. Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development. Free Radic Biol Med. 37:1304–1316.
6. Bakır S, Yazgan ÜC, İbiloğlu İ, Elbey B, Kızıl M, Kelle M., 2015. The protective effect of pomegranate extract against cisplatin toxicity in rat liver and kidney tissue. Arch Physiol Biochem. 121:152–156. DOI:10.3109/13813455.2015.1068336.
7. Betanzos-Cabrera G, Guerrero-Solano JA, Martínez-Pérez MM, Calderón-Ramos ZG, Belefant-Miller H, Cancino-Diaz JC., 2011. Pomegranate juice increases levels of paraoxonase1 (PON1) expression and enzymatic activity in streptozotocin-induced diabetic mice fed with a high-fat diet. Food Res Int. 44:1381–1385.
8. Bray HG, Thorpe WV., 1954. Analysis of phenolic compounds of interest in metabolism. Methods Biochem Anal. 1:27–52.
9. Cade WT., 2008. 2008 Nov. Diabetes-related microvascular and macrovascular diseases in the physical therapy setting. Phys Ther. 88:1322–1335. doi:10.2522/ptj.20080008
10. Cano A, Hernandez-Ruiz J, Garcia-Canovas F, Acosta M, Arnao MB., 1998. An end-point method for estimation of the total antioxidant activity in plant material. Phytochem Anal. 9:196–202.
11. Cao G, Muccitelli HU, Sanchez-Moreno C, Prior RL., 2001. Anthocyanins are absorbed in glycated forms in elderly women:a pharmacokinetic study. Am J Clin Nutr. 73:920–926.
12. Chung SS, Ho EC, Lam KS, Chung SK., 2003. Contribution of polyol pathway to diabetes-induced oxidative stress. J Am Soc Nephrol. 14:S233–S236.
13. Davidson MH, Maki KC, Dicklin MR, Feinstein SB, Witchger M, Bell M, McGuire DK, Provost JC, Liker H, Aviram M., 2009. Effects of consumption of pomegranate juice on carotid intima-media thickness in men and women at moderate risk for coronary heart disease. Am J Cardiol. 104:936–942.
14. Dembinska-Kiec A, Mykkanen O, Kiec-Wilk B, Mykkanen H., 2008. Antioxidant phytochemicals against type 2 diabetes. Br J Nutr. 99 E Suppl 1:ES109–ES117.
15. Hajimahmoodi M, Oveisi MR, Sadeghi N, Jannat B, Hadjibabaie M, Farahani E, Akrami MR, Namdar R., 2008. Antioxidant properties of peel and pulp hydro extract in ten Persian pomegranate cultivars. Pak J Biol Sci. 11:1600–1604.
16. Ferretti G, Bacchetti T, Marchionni C, Caldarelli L, Curatola G., 2001. Effect of glycation of high density lipoproteins on their physicochemical properties and on paraoxonase activity. Acta Diabetol. 38:163–169.
17. Fuhrman B, Volkova N, Aviram M., 2005. Pomegranate juice inhibits oxidized LDL uptake and cholesterol biosynthesis in macrophages. J Nutr Biochem. 16:570–576.
18. Ikeda Y, Suehiro T, Inoue M, Nakauchi Y, Morita T, Arii K, Ito H, Kumon Y, Hashimoto K., 1998. Serum paraoxonase activity and its relationship to diabetic complications in patients with non-insulin-dependent diabetes mellitus. Metabolism. 47:598–602.
19. Gaidukov L, Rosenblat M, Aviram M, Tawfik DS., 2006. The 192R/Q polymorphs of serum paraoxonase PON1 differ in HDL binding, lipolactonase stimulation, and cholesterol efflux. J Lipid Res. 47:2492–2502.
20. Giacco F, Brownlee M., 2010. Oxidative stress and diabetic complications. Circ Res. 107:1058–1070.
21. Gil MI, Tomas-Barberan FA, Hess-Pierce B, Holcroft DM, Kader AA., 2000. Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agric Food Chem. 48:4581–4589.
22. Kaplan M, Hayek T, Raz A, Coleman R, Dornfeld L, Vaya J, Aviram M., 2001. Pomegranate juice supplementation to atherosclerotic mice reduces macrophage lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J Nutr. 131:2082–2089.
23. Lotito SB, Zhang WJ, Yang CS, Crozier A, Frei B., 2011. Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties. Free Radic Biol Med. 51:454–463.
24. McGhie TK, Ainge GD, Barnett LE, Cooney JM, Jensen DJ., 2003. Anthocyanin glycosides from berry fruit are absorbed and excreted unmetabolized by both humans and rats. J Agric Food Chem. 51:4539–4548.
25. Nair SP, Shah NC, Taggarsi A, Nayak U., 2011. PONI and its association with oxidative stress in type I and type II diabetes mellitus. Diabetes Metab Syndr. 5:126–129.
26. Naka Y, Bucciarelli LG, Wendt T, Lee LK, Rong LL, Ramasamy R, Yan SF, Schmidt AM., 2004. RAGE axis:Animal models and novel insights into the vascular complications of diabetes. Arterioscler Thromb Vasc Biol. 24:1342–1349.
27. Parsaeyan N, Mozaffari-Khosravi H, Mozayan MR., 2012. Effect of pomegranate juice on paraoxonase enzyme activity in patients with type 2 diabetes. J Diabetes Metab Disord. 11:11.
28. Rock W, Rosenblat M, Miller-Lotan R, Levy AP, Elias M, Aviram M., 2008. Consumption of wonderful variety pomegranate juice and extract by diabetic patients increases paraoxonase 1 association with high-density lipoprotein and stimulates its catalytic activities. J Agric Food Chem. 56:8704–8713.
29. Romero-Aroca P, Fernández-Balart J, Baget-Bernaldiz M, Martinez-Salcedo I, Méndez-Marín I, Salvat-Serra M, Buil-Calvo JA., 2009. Changes in the diabetic retinopathy epidemiology after 14 years in a population of Type 1 and 2 diabetic patients after the new diabetes mellitus diagnosis criteria and a more strict control of the patients. J Diabetes Complications. 23:229–238. doi:10.1016/j.jdiacomp.2008.02.012.
30. Rosenblat M, Volkova N, Coleman R, Aviram M., 2006a. Pomegranate byproduct administration to apolipoprotein e-deficient mice attenuates atherosclerosis development as a result of decreased macrophage oxidative stress and reduced cellular uptake of oxidized low-density lipoprotein. J Agric Food Chem. 54:1928–1935.
31. Rosenblat M, Hayek T, Aviram M., 2006b. 0Anti-oxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages. Atherosclerosis. 187:363–371.
32. Seeram NP, Aviram M, Zhang Y, Henning SM, Feng L, Dreher M, Heber D., 2008. Comparison of antioxidant potency of commonly consumed polyphenol-rich beverages in the United States. J Agric Food Chem. 56:1415–1422.
33. Sozer V, Himmetoglu S, Korkmaz GG, Kaya S, Aydin S, Yumuk V, Hatemi H, Uzun H., 2014. Paraoxonase, oxidized low density lipoprotein, monocyte chemoattractant protein-1 and adhesion molecules are associated with macrovascular complications in patients with type 2 diabetes mellitus. Minerva Medica. 105:237–244.
34. Tsuzura S, Ikeda Y, Suehiro T, Ota K, Osaki F, Arii K, Kumon Y, Hashimoto K., 2004. Correlation of plasma oxidized low-density lipoprotein levels to vascular complications and human serum paraoxonase in patients with type 2 diabetes. Metabolism. 53:297–302.
35. Wahlberg G, Adamson U, Svensson J., 2000. Pyridine nucleotides in glucose metabolism and diabetes:a review. Diabetes Metab Res Rev. 16:33–42.
36. Whiteside CI., 2005. Cellular mechanisms and treatment of diabetes vascular complications converge on reactive oxygen species. Curr Hypertens Rep. 7:148–154.
37. Whiting DR, Guariguata L, Weil C, Shaw J., 2011. IDF diabetes atlas:global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract. 94:311–321.
38. Wild S, Roglic G, Green A, Sicree R, King H., 2004. Global prevalence of diabetes:estimates for the year 2000 and projections for 2030. Diabetes Care. 27:1047–1053.