Bile acids destabilise HIF-1α and promote anti-tumour phenotypes in cancer cell models

BMC Cancer

Volumn 16, Issue 1, 2016, Pages

  Phelan, J P ^a   Reen, F J ^a   Dunphy, N ^a   O'Connor, R ^a   O'Gara, F ^a,b  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b CURTIN UNIVERSITY   (Australia)

Author keywords

Bile acids; Cancer models; Dimethyloxaloglycine (DMOG); HIF 1 transcription factor; HIF 1 subunit; Hypoxia

Indexed keywords

BILE ACID; CHENODEOXYCHOLIC ACID; DEOXYCHOLIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LACTATE DEHYDROGENASE; OXYGEN; HIF1A PROTEIN, HUMAN;

ARTICLE; BREAST CANCER CELL LINE; CANCER CELL; CANCER GROWTH; CELL ADHESION; CELL INVASION; CELL MIGRATION; CLONOGENESIS; CONTROLLED STUDY; CYTOTOXICITY; ENZYME RELEASE; HUMAN; HUMAN CELL; HYPOXIA; LUNG CANCER CELL LINE; PHENOTYPE; PROSTATE CANCER CELL LINE; PROTEIN EXPRESSION; PROTEIN STABILITY; APOPTOSIS; CELL MOTION; CELL PROLIFERATION; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

APOPTOSIS; BILE ACIDS AND SALTS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; PHENOTYPE; PROTEIN STABILITY;

EID: 84987725285     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-016-2528-2     Document Type: Article

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