A casein hydrolysate protects mice against high fat diet induced hyperglycemia by attenuating NLRP3 inflammasome-mediated inflammation and improving insulin signaling

Molecular Nutrition and Food Research

Volumn 60, Issue 11, 2016, Pages 2421-2432

  Healy, Niamh P ^a   Kirwan, Anna M ^a   McArdle, Maeve A ^a   Holohan, Kieran ^a   Nongonierma, Alice B ^b   Keane, Deirdre ^a   Kelly, Stacey ^a   Celkova, Lucia ^a   Lyons, Claire L ^a   McGillicuddy, Fiona C ^a   Finucane, Orla M ^a   Murray, Brian A ^c   Kelly, Philip M ^c   Brennan, Lorraine ^a   FitzGerald, Richard J ^b   Roche, Helen M ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF LIMERICK   (Ireland)

^c TEAGASC FOOD RESEARCH CENTRE   (Ireland)

Author keywords

Adipose tissue; Functional food; Inflammation; Obesity; Type 2 diabetes

Indexed keywords

CASEIN; CASEIN HYDROLYSATE; CRYOPYRIN; CYTOKINE; INFLAMMASOME; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; NLRP3 PROTEIN, MOUSE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; TUMOR NECROSIS FACTOR;

3T3-L1 CELL LINE; ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; DIET THERAPY; DRUG EFFECTS; HYPERGLYCEMIA; INFLAMMATION; INSULIN RESISTANCE; LIPID DIET; METABOLISM; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PHYSIOLOGY; SECRETION (PROCESS);

3T3-L1 CELLS; ADIPOSE TISSUE; ANIMALS; CASEINS; CYTOKINES; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; HYPERGLYCEMIA; INFLAMMASOMES; INFLAMMATION; INSULIN; INSULIN RESISTANCE; INTERLEUKIN-1BETA; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; NLR PROTEINS; OBESITY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84987657427     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201501054     Document Type: Article

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