Cardiac Fibroblast GRK2 Deletion Enhances Contractility and Remodeling Following Ischemia/Reperfusion Injury

Circulation Research

Volumn 119, Issue 10, 2016, Pages 1116-1127

  Woodall, Meryl C ^a   Woodall, Benjamin P ^a   Gao, Erhe ^a   Yuan, Ancai ^a,b   Koch, Walter J ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

cardiac fibroblast; fibrosis; G protein coupled receptor kinase 2; inflammation; myocardial ischemia reperfusion injury

Indexed keywords

G PROTEIN COUPLED RECEPTOR KINASE 2; TUMOR NECROSIS FACTOR; ADRBK1 PROTEIN, MOUSE; ADRBK1 PROTEIN, RAT; CYCLIC AMP; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEART EJECTION FRACTION; HEART FIBROBLAST; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE FIBROSIS; KNOCKOUT MOUSE; MALE; MOUSE; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; CARDIAC MUSCLE; DEFICIENCY; DRUG EFFECTS; ENZYMOLOGY; FIBROBLAST; FIBROSIS; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; GENETICS; HEART; HEART CONTRACTION; HEART MUSCLE ISCHEMIA; HEART STROKE VOLUME; METABOLISM; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; SECOND MESSENGER; SECRETION (PROCESS);

ANIMALS; ANIMALS, NEWBORN; CYCLIC AMP; FIBROBLASTS; FIBROSIS; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GENE EXPRESSION REGULATION; HEART; MICE; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NEUTROPHIL INFILTRATION; NF-KAPPA B; RATS; RNA, SMALL INTERFERING; SECOND MESSENGER SYSTEMS; STROKE VOLUME; TRANSDUCTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84987623603     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.309538     Document Type: Article

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