메뉴 건너뛰기




Volumn 204, Issue 1, 2016, Pages 371-383

The genetic basis of natural variation in Caenorhabditis elegans telomere length

Author keywords

Caenorhabditis elegans; QTL; Shelterin; Telomere length; Whole genome sequence

Indexed keywords

HELMINTH DNA; OLIGONUCLEOTIDE; PROTECTION OF TELOMERES 2; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; DNA; TELOMERE BINDING PROTEIN;

EID: 84986321393     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.116.191148     Document Type: Article
Times cited : (94)

References (75)
  • 1
    • 84857551173 scopus 로고    scopus 로고
    • Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity
    • Andersen, E. C., J. P. Gerke, J. A. Shapiro, J. R. Crissman, R. Ghosh et al., 2012 Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity. Nat. Genet. 44: 285-290.
    • (2012) Nat. Genet , vol.44 , pp. 285-290
    • Andersen, E.C.1    Gerke, J.P.2    Shapiro, J.A.3    Crissman, J.R.4    Ghosh, R.5
  • 2
    • 84901740617 scopus 로고    scopus 로고
    • A Variant in the Neuropeptide Receptor npr-1 is a Major Determinant of Caenorhabditis elegans Growth and Physiology
    • Andersen, E. C., J. S. Bloom, J. P. Gerke, and L. Kruglyak, 2014 A Variant in the Neuropeptide Receptor npr-1 is a Major Determinant of Caenorhabditis elegans Growth and Physiology. PLoS Genet. 10: e1004156.
    • (2014) Plos Genet , pp. 10
    • Andersen, E.C.1    Bloom, J.S.2    Gerke, J.P.3    Kruglyak, L.4
  • 4
    • 27644574342 scopus 로고    scopus 로고
    • Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
    • Armanios, M., J.-L. Chen, Y.-P. C. Chang, and R. A. Brodsky, A. Hawkins et al., 2005 Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita. Proc. Natl. Acad. Sci. USA 102: 15960-15964.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 15960-15964
    • Armanios, M.1    Chen, J.-L.2    Chang, Y.-P.C.3    Brodsky, R.A.4    Hawkins, A.5
  • 6
    • 0025731583 scopus 로고
    • Structure and function of telomeres
    • Blackburn, E. H., 1991 Structure and function of telomeres. Nature 350: 569-573.
    • (1991) Nature , vol.350 , pp. 569-573
    • Blackburn, E.H.1
  • 7
    • 84905049901 scopus 로고    scopus 로고
    • Trimmomatic: A flexible trimmer for Illumina sequence data
    • Bolger, A. M., M. Lohse, and B. Usadel, 2014 Trimmomatic: A flexible trimmer for Illumina sequence data. Bioinformatics 30: 2114-2120.
    • (2014) Bioinformatics , vol.30 , pp. 2114-2120
    • Bolger, A.M.1    Lohse, M.2    Usadel, B.3
  • 8
    • 77952772868 scopus 로고    scopus 로고
    • A high-throughput method for assessing chemical toxicity using a Caenorhabditis elegans reproduction assay
    • Boyd, W. A., S. J. McBride, J. R. Rice, D. W. Snyder, and J. H. Freedman, 2010 A high-throughput method for assessing chemical toxicity using a Caenorhabditis elegans reproduction assay. Toxicol. Appl. Pharmacol. 245: 153-159.
    • (2010) Toxicol. Appl. Pharmacol , vol.245 , pp. 153-159
    • Boyd, W.A.1    McBride, S.J.2    Rice, J.R.3    Snyder, D.W.4    Freedman, J.H.5
  • 9
    • 84884594493 scopus 로고    scopus 로고
    • Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect
    • Broer, L., V. Codd, D. R. Nyholt, J. Deelen, M. Mangino et al., 2013 Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. Eur. J. Hum. Genet. 21: 1163-1168.
    • (2013) Eur. J. Hum. Genet , vol.21 , pp. 1163-1168
    • Broer, L.1    Codd, V.2    Nyholt, D.R.3    Deelen, J.4    Mangino, M.5
  • 10
    • 84954234248 scopus 로고    scopus 로고
    • Genotype Imputation with Millions of Reference Samples
    • Browning, B. L., and S. R. Browning, 2016 Genotype Imputation with Millions of Reference Samples. Am. J. Hum. Genet. 98: 116-126.
    • (2016) Am. J. Hum. Genet , vol.98 , pp. 116-126
    • Browning, B.L.1    Browning, S.R.2
  • 11
    • 63349111567 scopus 로고    scopus 로고
    • Telomere length measurement by a novel monochrome multiplex quantitative PCR method
    • Cawthon, R. M., 2009 Telomere length measurement by a novel monochrome multiplex quantitative PCR method. Nucleic Acids Res. 37: 1-7.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-7
    • Cawthon, R.M.1
  • 12
    • 84861204297 scopus 로고    scopus 로고
    • Caenorhabditis elegans POT-2 telomere protein represses a mode of alternative lengthening of telomeres with normal telomere lengths
    • Cheng, C., L. Shtessel, M. M. Brady, and S. Ahmed, 2012 Caenorhabditis elegans POT-2 telomere protein represses a mode of alternative lengthening of telomeres with normal telomere lengths. Proc. Natl. Acad. Sci. USA 109: 7805-7810.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 7805-7810
    • Cheng, C.1    Shtessel, L.2    Brady, M.M.3    Ahmed, S.4
  • 13
    • 3242725203 scopus 로고    scopus 로고
    • Strain-specific telomere length revealed by single telomere length analysis in Caenorhabditis elegans
    • Cheung, I., M. Schertzer, A. Baross, A. M. Rose, P. M. Lansdorp et al., 2004 Strain-specific telomere length revealed by single telomere length analysis in Caenorhabditis elegans. Nucleic Acids Res. 32: 3383-3391.
    • (2004) Nucleic Acids Res , vol.32 , pp. 3383-3391
    • Cheung, I.1    Schertzer, M.2    Baross, A.3    Rose, A.M.4    Lansdorp, P.M.5
  • 14
    • 31544444692 scopus 로고    scopus 로고
    • High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans
    • Cheung, I., M. Schertzer, A. Rose, and P. M. Lansdorp, 2006 High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans. Nucleic Acids Res. 34: 96-103.
    • (2006) Nucleic Acids Res , vol.34 , pp. 96-103
    • Cheung, I.1    Schertzer, M.2    Rose, A.3    Lansdorp, P.M.4
  • 15
    • 84862506964 scopus 로고    scopus 로고
    • A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w 1118; iso-2; iso-3
    • Cingolani, P., A. Platts, L. L. L. Wang, M. Coon, T. Nguyen et al., 2012 A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w 1118; iso-2; iso-3. Fly (Austin) 6: 80-92.
    • (2012) Fly (Austin) , vol.6 , pp. 80-92
    • Cingolani, P.1    Platts, A.2    Wang, L.L.L.3    Coon, M.4    Nguyen, T.5
  • 16
    • 84874967142 scopus 로고    scopus 로고
    • Identification of seven loci affecting mean telomere length and their association with disease
    • Codd, V., C. P. Nelson, E. Albrecht, M. Mangino, J. Deelen et al., 2013 Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet. 45: 422-427e2.
    • (2013) Nat Genet , vol.45 , pp. 422-427
    • Codd, V.1    Nelson, C.P.2    Albrecht, E.3    Mangino, M.4    Deelen, J.5
  • 17
    • 44349136891 scopus 로고    scopus 로고
    • Telomere dysfunction and tumour suppression: The senescence connection
    • Deng, Y., S. S. Chan, and S. Chang, 2008 Telomere dysfunction and tumour suppression: the senescence connection. Nat. Rev. Cancer 8: 450-458.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 450-458
    • Deng, Y.1    Chan, S.S.2    Chang, S.3
  • 19
    • 3042666256 scopus 로고    scopus 로고
    • MUSCLE: Multiple sequence alignment with high accuracy and high throughput
    • Edgar, R. C., 2004 MUSCLE: Multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res. 32: 1792-1797.
    • (2004) Nucleic Acids Res , vol.32 , pp. 1792-1797
    • Edgar, R.C.1
  • 20
    • 85136354327 scopus 로고    scopus 로고
    • Ridge Regression and Other Kernels for Genomic Selection with R Package rrBLUP
    • Endelman, J. B., 2011 Ridge Regression and Other Kernels for Genomic Selection with R Package rrBLUP. Plant Genome J. 4: 250-255.
    • (2011) Plant Genome J , vol.4 , pp. 250-255
    • Endelman, J.B.1
  • 21
    • 78649295230 scopus 로고    scopus 로고
    • The natural history of Caenorhabditis elegans
    • Félix, M.-A., and C. Braendle, 2010 The natural history of Caenorhabditis elegans. Curr. Biol. 20: R965-R969.
    • (2010) Curr. Biol , vol.20 , pp. R965-R969
    • Félix, M.-A.1    Braendle, C.2
  • 22
    • 77954589779 scopus 로고    scopus 로고
    • Oligonucleotide/oligosaccharidebinding fold proteins: A growing family of genome guardians
    • Flynn, R. L., and L. Zou, 2010 Oligonucleotide/oligosaccharidebinding fold proteins: a growing family of genome guardians. Crit. Rev. Biochem. Mol. Biol. 45: 266-275.
    • (2010) Crit. Rev. Biochem. Mol. Biol , vol.45 , pp. 266-275
    • Flynn, R.L.1    Zou, L.2
  • 23
    • 13144305133 scopus 로고    scopus 로고
    • The rate of telomere sequence loss in human leukocytes varies with age
    • Frenck, R. W., Jr., E. H. Blackburn, and K. M. Shannon, 1998 The rate of telomere sequence loss in human leukocytes varies with age. Proc. Natl. Acad. Sci. USA 95: 5607-5610.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5607-5610
    • Frenck, R.W.1    Blackburn, E.H.2    Shannon, K.M.3
  • 24
    • 84936777477 scopus 로고    scopus 로고
    • Genetic Architecture of Natural Variation of Telomere Length in Arabidopsis thaliana
    • Fulcher, N., A. Teubenbacher, E. Kerdaffrec, A. Farlow, M. Nordborg et al., 2014 Genetic Architecture of Natural Variation of Telomere Length in Arabidopsis thaliana. Genetics 199: 625-635.
    • (2014) Genetics , vol.199 , pp. 625-635
    • Fulcher, N.1    Teubenbacher, A.2    Kerdaffrec, E.3    Farlow, A.4    Nordborg, M.5
  • 25
    • 33645793749 scopus 로고    scopus 로고
    • Telomere length as a quantitative trait: Genomewide survey and genetic mapping of telomere length-control genes in yeast
    • Gatbonton, T., M. Imbesi, M. Nelson, J. M. Akey, D. M. Ruderfer et al., 2006 Telomere length as a quantitative trait: Genomewide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet. 2: e35.
    • (2006) Plos Genet , pp. 2
    • Gatbonton, T.1    Imbesi, M.2    Nelson, M.3    Akey, J.M.4    Ruderfer, D.M.5
  • 26
    • 84986331099 scopus 로고    scopus 로고
    • FASTX Toolkit, FASTQ/A short-reads pre-processing tools
    • Gordon, A., and G. J. Hannon, 2010 FASTX Toolkit, FASTQ/A short-reads pre-processing tools. Hannon Lab. Available at: http://hannonlab.cshl.edu/fastx_toolkit. Accessed January, 2016.
    • (2010) Hannon Lab
    • Gordon, A.1    Hannon, G.J.2
  • 28
    • 0026628668 scopus 로고
    • The telomere hypothesis of cellular aging. Exp
    • Harley, C. B., H. Vaziri, C. M. Counter, and R. C. Allsopp, 1992 The telomere hypothesis of cellular aging. Exp. Gerontol. 27: 375-382.
    • (1992) Gerontol , vol.27 , pp. 375-382
    • Harley, C.B.1    Vaziri, H.2    Counter, C.M.3    Allsopp, R.C.4
  • 31
    • 34248526205 scopus 로고    scopus 로고
    • Telomerase and the aging process
    • Hornsby, P. J., 2007 Telomerase and the aging process. Exp. Gerontol. 42: 575-581.
    • (2007) Exp. Gerontol , vol.42 , pp. 575-581
    • Hornsby, P.J.1
  • 32
    • 2642530948 scopus 로고    scopus 로고
    • Long lifespan in worms with long telomeric DNA
    • Joeng, K. S., E. J. Song, K.-J. Lee, and J. Lee, 2004 Long lifespan in worms with long telomeric DNA. Nat. Genet. 36: 607-611.
    • (2004) Nat. Genet , vol.36 , pp. 607-611
    • Joeng, K.S.1    Song, E.J.2    Lee, K.-J.3    Lee, J.4
  • 33
    • 84855194845 scopus 로고    scopus 로고
    • TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres
    • Jones, A. M., A. D. Beggs, L. Carvajal-Carmona, and S. Farrington, A. Tenesa et al., 2012 TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres. Gut. 61: 248-254.
    • (2012) Gut , vol.61 , pp. 248-254
    • Jones, A.M.1    Beggs, A.D.2    Carvajal-Carmona, L.3    Farrington, S.4    Tenesa, A.5
  • 34
    • 80052325960 scopus 로고    scopus 로고
    • Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast
    • Kwan, E. X., E. Foss, L. Kruglyak, and A. Bedalov, 2011 Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast. PLoS Genet. 7: e1002250.
    • (2011) Plos Genet , pp. 7
    • Kwan, E.X.1    Foss, E.2    Kruglyak, L.3    Bedalov, A.4
  • 35
    • 84924966448 scopus 로고    scopus 로고
    • The Drosophila Genome Nexus: A Population Genomic Resource of 623 Drosophila melanogaster Genomes, Including 197 from a Single Ancestral Range Population
    • Lack, J. B., C. M. Cardeno, M. W. Crepeau, W. Taylor, R. B. Corbett-Detig et al., 2015 The Drosophila Genome Nexus: A Population Genomic Resource of 623 Drosophila melanogaster Genomes, Including 197 from a Single Ancestral Range Population. Genetics 199: 1229-1241.
    • (2015) Genetics , vol.199 , pp. 1229-1241
    • Lack, J.B.1    Cardeno, C.M.2    Crepeau, M.W.3    Taylor, W.4    Corbett-Detig, R.B.5
  • 36
    • 80052398381 scopus 로고    scopus 로고
    • How shelterin solves the telomere end-protection problem. Cold Spring Harb
    • De Lange, T., 2010 How shelterin solves the telomere end-protection problem. Cold Spring Harb. Symp. Quant. Biol. 75: 167-177.
    • (2010) Symp. Quant. Biol , vol.75 , pp. 167-177
    • De Lange, T.1
  • 37
    • 12844265975 scopus 로고    scopus 로고
    • Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
    • Lei, M., E. R. Podell, and T. R. Cech, 2004 Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection. Nat. Struct. Mol. Biol. 11: 1223-1229.
    • (2004) Nat. Struct. Mol. Biol , vol.11 , pp. 1223-1229
    • Lei, M.1    Podell, E.R.2    Cech, T.R.3
  • 38
    • 77952703980 scopus 로고    scopus 로고
    • Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology
    • Levy, D., S. L. Neuhausen, S. C. Hunt, M. Kimura, S.-J. Hwang et al., 2010 Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proc. Natl. Acad. Sci. USA 107: 9293-9298.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 9293-9298
    • Levy, D.1    Neuhausen, S.L.2    Hunt, S.C.3    Kimura, M.4    Hwang, S.-J.5
  • 40
    • 80054915847 scopus 로고    scopus 로고
    • A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data
    • Li, H., 2011 A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data. Bioinformatics 27: 2987-2993.
    • (2011) Bioinformatics , vol.27 , pp. 2987-2993
    • Li, H.1
  • 41
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • Li, H., and R. Durbin, 2009 Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25: 1754-1760.
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 42
    • 70349668987 scopus 로고    scopus 로고
    • Segregating YKU80 and TLC1 alleles underlying natural variation in telomere properties in wild yeast
    • Liti, G., S. Haricharan, F. A. Cubillos, A. L. Tierney, S. Sharp et al., 2009 Segregating YKU80 and TLC1 alleles underlying natural variation in telomere properties in wild yeast. PLoS Genet. 5: e1000659.
    • (2009) Plos Genet , pp. 5
    • Liti, G.1    Haricharan, S.2    Cubillos, F.A.3    Tierney, A.L.4    Sharp, S.5
  • 44
    • 0034720806 scopus 로고    scopus 로고
    • Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans
    • Malik, H. S., W. D. Burke, and T. H. Eickbush, 2000 Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans. Gene 251: 101-108.
    • (2000) Gene , vol.251 , pp. 101-108
    • Malik, H.S.1    Burke, W.D.2    Eickbush, T.H.3
  • 45
    • 19444383162 scopus 로고    scopus 로고
    • Dyskeratosis congenita: Telomerase, telomeres and anticipation
    • Marrone, A., A. Walne, and I. Dokal, 2005 Dyskeratosis congenita: Telomerase, telomeres and anticipation. Curr. Opin. Genet. Dev. 15: 249-257.
    • (2005) Curr. Opin. Genet. Dev , vol.15 , pp. 249-257
    • Marrone, A.1    Walne, A.2    Dokal, I.3
  • 46
    • 42349112088 scopus 로고    scopus 로고
    • Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
    • McCarthy, M. I., G.R. Abecasis, L. R. Cardon, D. B. Goldstein, and J. Little et al., 2008 Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat. Rev. Genet. 9: 356-369.
    • (2008) Nat. Rev. Genet , vol.9 , pp. 356-369
    • McCarthy, M.I.1    Abecasis, G.R.2    Cardon, L.R.3    Goldstein, D.B.4    Little, J.5
  • 48
    • 61849084704 scopus 로고    scopus 로고
    • Quantitative Mapping of a Digenic Behavioral Trait Implicates Globin Variation in C. Elegans Sensory Behaviors
    • McGrath, P. T., M. V. Rockman, M. Zimmer, H. Jang, E. Z. Macosko et al., 2009 Quantitative Mapping of a Digenic Behavioral Trait Implicates Globin Variation in C. elegans Sensory Behaviors. Neuron 61: 692-699.
    • (2009) Neuron , vol.61 , pp. 692-699
    • McGrath, P.T.1    Rockman, M.V.2    Zimmer, M.3    Jang, H.4    Macosko, E.Z.5
  • 49
    • 84876427223 scopus 로고    scopus 로고
    • Phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data
    • McMurdie, P. J., and S. Holmes, 2013 Phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data. PLoS One 8: e61217.
    • (2013) Plos One , pp. 8
    • McMurdie, P.J.1    Holmes, S.2
  • 50
    • 33645512251 scopus 로고    scopus 로고
    • Trt-1 is the Caenorhabditis elegans catalytic subunit of telomerase
    • Meier, B., I. Clejan, Y. Liu, M. Lowden, A. Gartner et al., 2006 trt-1 is the Caenorhabditis elegans catalytic subunit of telomerase. PLoS Genet. 2: 187-197.
    • (2006) Plos Genet , vol.2 , pp. 187-197
    • Meier, B.1    Clejan, I.2    Liu, Y.3    Lowden, M.4    Gartner, A.5
  • 51
    • 70450222723 scopus 로고    scopus 로고
    • The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans
    • Meier, B., L. J. Barber, L. Shtessel, S. J. Boulton, A. Gartner et al., 2009 The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans. EMBO J. 28: 3549-3563.
    • (2009) EMBO J , vol.28 , pp. 3549-3563
    • Meier, B.1    Barber, L.J.2    Shtessel, L.3    Boulton, S.J.4    Gartner, A.5
  • 52
    • 84945532586 scopus 로고    scopus 로고
    • Natural Variation in plep-1 Causes Male-Male Copulatory Behavior in C. Elegans
    • Noble, L. M., A. S. Chang, D. McNelis, M. Kramer, M. Yen et al., 2015 Natural Variation in plep-1 Causes Male-Male Copulatory Behavior in C. Elegans. Curr. Biol. 25: 2730-2737.
    • (2015) Curr. Biol , vol.25 , pp. 2730-2737
    • Noble, L.M.1    Chang, A.S.2    McNelis, D.3    Kramer, M.4    Yen, M.5
  • 53
    • 77649180958 scopus 로고    scopus 로고
    • Telomeres: Protecting chromosomes against genome instability
    • O’Sullivan, R. J., and J. Karlseder, 2010 Telomeres: protecting chromosomes against genome instability. Nat. Rev. Mol. Cell Biol. 11: 171-181.
    • (2010) Nat. Rev. Mol. Cell Biol , vol.11 , pp. 171-181
    • O’Sullivan, R.J.1    Karlseder, J.2
  • 54
    • 1042304216 scopus 로고    scopus 로고
    • APE: Analyses of phylogenetics and evolution in R language
    • Paradis, E., J. Claude, and K. Strimmer, 2004 APE: Analyses of phylogenetics and evolution in R language. Bioinformatics 20: 289-290.
    • (2004) Bioinformatics , vol.20 , pp. 289-290
    • Paradis, E.1    Claude, J.2    Strimmer, K.3
  • 55
    • 0033178240 scopus 로고    scopus 로고
    • Telomere length measurements using digital fluorescence microscopy
    • Poon, S. S., U. M. Martens, R. K. Ward, and P. M. Lansdorp, 1999 Telomere length measurements using digital fluorescence microscopy. Cytometry 36: 267-278.
    • (1999) Cytometry , vol.36 , pp. 267-278
    • Poon, S.S.1    Martens, U.M.2    Ward, R.K.3    Lansdorp, P.M.4
  • 56
  • 57
    • 33644796076 scopus 로고    scopus 로고
    • Uncoupling of longevity and telomere length in C, elegans
    • Raices, M., H. Maruyama, A. Dillin, and J. Kariseder, 2005 Uncoupling of longevity and telomere length in C, elegans. PLoS Genet. 1: 295-301.
    • (2005) Plos Genet , vol.1 , pp. 295-301
    • Raices, M.1    Maruyama, H.2    Dillin, A.3    Kariseder, J.4
  • 58
    • 39749176333 scopus 로고    scopus 로고
    • C. Elegans Telomeres Contain G-Strand and C-Strand Overhangs that Are Bound by Distinct Proteins
    • Raices, M., R. E. Verdun, S. A. Compton, C. I. Haggblom, J. D. Griffith et al., 2008 C. elegans Telomeres Contain G-Strand and C-Strand Overhangs that Are Bound by Distinct Proteins. Cell 132: 745-757.
    • (2008) Cell , vol.132 , pp. 745-757
    • Raices, M.1    Verdun, R.E.2    Compton, S.A.3    Haggblom, C.I.4    Griffith, J.D.5
  • 59
    • 61849143272 scopus 로고    scopus 로고
    • Recombinational landscape and population genomics of Caenorhabditis elegans
    • Rockman, M. V., and L. Kruglyak, 2009 Recombinational landscape and population genomics of Caenorhabditis elegans. PLoS Genet. 5: e1000419.
    • (2009) Plos Genet , pp. 5
    • Rockman, M.V.1    Kruglyak, L.2
  • 60
    • 0033990048 scopus 로고    scopus 로고
    • Bioinformatics Methods and Protocols, edited by S. Misener and S. A. Krawetz. Methods Mol. Biol. TM 132. Humana Press
    • Rozen, S., and H. J. Skaletsky, 2000 Primer3 on the WWW for General Users and for Biologist Programmers, pp. 365-386 in Bioinformatics Methods and Protocols, edited by S. Misener and S. A. Krawetz. Methods Mol. Biol. TM 132. Humana Press.
    • (2000) Primer3 on the WWW for General Users and for Biologist Programmers , pp. 365-386
    • Rozen, S.1    Skaletsky, H.J.2
  • 61
    • 77956615870 scopus 로고    scopus 로고
    • Sizing the ends: Normal length of human telomeres
    • Samassekou, O., M. Gadji, R. Drouin, and J. Yan, 2010 Sizing the ends: Normal length of human telomeres. Ann. Anat. 192: 284-291.
    • (2010) Ann. Anat , vol.192 , pp. 284-291
    • Samassekou, O.1    Gadji, M.2    Drouin, R.3    Yan, J.4
  • 62
    • 84942016751 scopus 로고    scopus 로고
    • Telomere maintenance through recruitment of internal genomic regions
    • Seo, B., C. Kim, M. Hills, S. Sung, H. Kim et al., 2015 Telomere maintenance through recruitment of internal genomic regions. Nat. Commun. 6: 8189.
    • (2015) Nat. Commun , vol.6 , pp. 8189
    • Seo, B.1    Kim, C.2    Hills, M.3    Sung, S.4    Kim, H.5
  • 63
    • 84908179510 scopus 로고    scopus 로고
    • COPASutils: An R Package for Reading, Processing, and Visualizing Data from COPAS Large-Particle Flow Cytometers
    • Shimko, T. C., and E. C. Andersen, 2014 COPASutils: An R Package for Reading, Processing, and Visualizing Data from COPAS Large-Particle Flow Cytometers. PLoS One 9: e111090.
    • (2014) Plos One , pp. 9
    • Shimko, T.C.1    Andersen, E.C.2
  • 64
    • 84883187057 scopus 로고    scopus 로고
    • Caenorhabditis elegans POT-1 and POT-2 repress telomere maintenance pathways
    • Shtessel, L., M. R. Lowden, C. Cheng, M. Simon, K. Wang et al., 2013 Caenorhabditis elegans POT-1 and POT-2 repress telomere maintenance pathways. G3 (Bethesda) 3: 305-313.
    • (2013) G3 (Bethesda) , vol.3 , pp. 305-313
    • Shtessel, L.1    Lowden, M.R.2    Cheng, C.3    Simon, M.4    Wang, K.5
  • 65
    • 84858337182 scopus 로고    scopus 로고
    • Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: A cross-sectional and longitudinal analysis
    • Soerensen, M., M. Thinggaard, M. Nygaard, S. Dato, Q. Tan et al., 2012 Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: A cross-sectional and longitudinal analysis. Aging Cell 11: 223-227.
    • (2012) Aging Cell , vol.11 , pp. 223-227
    • Soerensen, M.1    Thinggaard, M.2    Nygaard, M.3    Dato, S.4    Tan, Q.5
  • 66
    • 0035165576 scopus 로고    scopus 로고
    • WormBase: Network access to the genome and biology of Caenorhabditis elegans
    • Stein, L., P. Sternberg, R. Durbin, J. Thierry-Mieg, and J. Spieth, 2001 WormBase: network access to the genome and biology of Caenorhabditis elegans. Nucleic Acids Res. 29: 82-86.
    • (2001) Nucleic Acids Res , vol.29 , pp. 82-86
    • Stein, L.1    Sternberg, P.2    Durbin, R.3    Thierry-Mieg, J.4    Spieth, J.5
  • 68
    • 84986311177 scopus 로고    scopus 로고
    • Maintenance of C. Elegans. WormBook 11: 1-11. The 1000 Genomes Project Consortium, 2012 An integrated map of genetic variation from 1,092 human genomes
    • Stiernagle, T., 2006 Maintenance of C. elegans. WormBook 11: 1-11. The 1000 Genomes Project Consortium, 2012 An integrated map of genetic variation from 1,092 human genomes. Nature 491: 56-65.
    • (2006) Nature , vol.491 , pp. 56-65
    • Stiernagle, T.1
  • 70
    • 84884266257 scopus 로고    scopus 로고
    • The million mutation project: A new approach to genetics in Caenorhabditis elegans
    • Thompson, O., M. Edgley, P. Strasbourger, S. Flibotte, B. Ewing et al., 2013 The million mutation project: A new approach to genetics in Caenorhabditis elegans. Genome Res. 23: 1749-1762.
    • (2013) Genome Res , vol.23 , pp. 1749-1762
    • Thompson, O.1    Edgley, M.2    Strasbourger, P.3    Flibotte, S.4    Ewing, B.5
  • 71
    • 2442617343 scopus 로고    scopus 로고
    • Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC
    • Vulliamy, T., A. Marrone, R. Szydlo, A. Walne, P. J. Mason et al., 2004 Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC. Nat. Genet. 36: 447-449.
    • (2004) Nat. Genet , vol.36 , pp. 447-449
    • Vulliamy, T.1    Marrone, A.2    Szydlo, R.3    Walne, A.4    Mason, P.J.5
  • 72
    • 0015515155 scopus 로고
    • Origin of concatemeric T7 DNA
    • Watson, J. D., 1972 Origin of concatemeric T7 DNA. Nat. New Biol. 239: 197-201.
    • (1972) Nat. New Biol , vol.239 , pp. 197-201
    • Watson, J.D.1
  • 73
    • 68249140383 scopus 로고    scopus 로고
    • The 1001 genomes project for Arabidopsis thaliana
    • Weigel, D., and R. Mott, 2009 The 1001 genomes project for Arabidopsis thaliana. Genome Biol. 10: 107.
    • (2009) Genome Biol , vol.10 , pp. 107
    • Weigel, D.1    Mott, R.2
  • 74
    • 0034978075 scopus 로고    scopus 로고
    • Rapid gene mapping in Caenorhabditis elegans using a high density polymorphism map
    • Wicks, S. R., R. T. Yeh, W. R. Gish, R. H. Waterston, and R. H. Plasterk, 2001 Rapid gene mapping in Caenorhabditis elegans using a high density polymorphism map. Nat. Genet. 28: 160-164.
    • (2001) Nat. Genet , vol.28 , pp. 160-164
    • Wicks, S.R.1    Yeh, R.T.2    Gish, W.R.3    Waterston, R.H.4    Plasterk, R.H.5
  • 75
    • 0029787013 scopus 로고    scopus 로고
    • Telomeric repeats (TTAGGC)n are sufficient for chromosome capping function in Caenorhabditis elegans
    • Wicky, C., A. M. Villeneuve, N. Lauper, L. Codourey, H. Tobler, and F. Müller, 1996 Telomeric repeats (TTAGGC)n are sufficient for chromosome capping function in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 93: 8983-8988.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8983-8988
    • Wicky, C.1    Villeneuve, A.M.2    Lauper, N.3    Codourey, L.4    Tobler, H.5    Müller, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.