Long lifespan in worms with long telomeric DNA

Nature Genetics

Volumn 36, Issue 6, 2004, Pages 607-611

  Joeng, Kyu Sang ^a   Song, Eun Joo ^b   Lee, Kong Joo ^b   Lee, Junho ^a  

^a Yonsei University   (South Korea)

^b Ewha Womans University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DNA STRUCTURE; EMBRYO; GENE OVEREXPRESSION; GERM CELL; HEAT STRESS; LIFESPAN; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROGENY; SENESCENCE; SOMATIC CELL; STEM CELL; TELOMERE; WORM;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DNA, HELMINTH; GENE EXPRESSION; GENES, HELMINTH; LONGEVITY; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; TELOMERE; TELOMERE-BINDING PROTEINS;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 2642530948     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1356     Document Type: Article

References (27)

1. Krupp, G., Klapper, W. & Parwaresch, R. Cell proliferation, carcinogenesis and diverse mechanisms of telomerase regulation. Cell Mol. Life Sci. 57, 464-486 (2000).
2. Morin, G.B. Telomere control of replicative lifespan. Exp. Gerontol. 32, 375-382 (1997).
3. Harley, C.B., Vaziri, H., Counter, C.M. & Allsopp, R.C. The telomere hypothesis of cellular aging. Exp. Gerontol. 27, 375-382 (1992).
4. Rudolph, K.L. et al. Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 96, 701-712 (1999).
5. Bodnar, A.G. et al. Extension of life-span by introduction of telomerase into normal human cells. Science 279, 349-352 (1998).
6. Hemann, M.T. & Greider, C.W. Wild-derived inbred mouse strains have short telomeres. Nucleic Acids Res. 28, 4474-447 (2000).
7. Wicky, C. et al. Telomeric repeats (TTAGGC)n are sufficient for chromosome capping function in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 93, 8983-8988 (1996).
8. Lin, J.J. & Zakian, V.A. Isolation and characterization of two Saccharomyces cerevisiae genes that encode proteins that bind to (TG1-3)n single strand telomeric DNA in vitro. Nucleic Acids Res. 22, 4906-4913 (1994).
9. LaBranche, H. et al. Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase. Nat. Genet. 19, 199-202 (1998).
10. Fiset, S. & Chabot, B. hnRNP A1 may interact simultaneously with telomeric DNA and the human telomerase RNA in vitro. Nucleic Acids Res. 29, 2268-2275 (2001).
11. Ketting, R.F., Haverkamp, T.H., van Luenen, H.G. & Plasterk, R.H. Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. Cell 99, 133-141 (1999).
12. Lithgow, G.J., White, T.M., Hinerfeld, D.A. & Johnson, T.E. Thermotolerance of a long-lived mutant of Caenorhabditis elegans. J. Gerontol. 49, B270-276 (1994).
13. Lithgow, G.J., White, T.M., Melov, S. & Johnson, T.E. Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc. Natl. Acad. Sci. USA 92, 7540-7544 (1995).
14. Honda, Y. & Honda, S. The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB J. 13, 1385-1393 (1999).
15. Larsen, P.L. Aging and resistance to oxidative damage in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 90, 8905-8909 (1993).
16. Lin, K., Dorman, J.B., Rodan, A. & Kenyon, C. daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278, 1319-1322 (1997).
17. Ogg, S. et al. The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389, 994-999 (1997).
18. Lin, K., Hsin, H., Libina, N. & Kenyon, C. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat. Genet. 28, 139-145 (2001).
19. Hsin, H. & Kenyon, C. Signals from the reproductive system regulate the lifespan of C. elegans. Nature 399, 362-366 (1999).
20. Benard, C. et al. The C. elegans maternal-effect gene clk-2 is essential for embryonic development, encodes a protein homologous to yeast Tel2p and affects telomere length. Development 128, 4045-4055 (2001).
21. Lim, C.S., Mian, I.S., Dernburg, A.F. & Campisi, J. C. elegans clk-2, a gene that limits life span, encodes a telomere length regulator similar to yeast telomere binding protein Tel2p. Curr. Biol. 11, 1706-1710 (2001).
22. Ahmed, S., Alpi, A., Hengartner, M.O. & Gartner, A. C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein. Curr. Biol. 11, 1934-194. (2001).
23. Benard, C. & Hekimi, S. Long-lived mutants, the rate of aging, telomeres and the germline in Caenorhabditis elegans. Mech. Ageing Dev. 123, 869-880 (2002).
24. Cawthon, R.M., Smith, K.R., O'Brien, E., Sivatchenko, A. & Kerber, R.A. Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 361, 393-395 (2003).
25. Kwon, J.Y. et al. Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation. Proc. Natl. Acad. Sci. USA 96, 14990-14995 (1999).
26. Mello, C.C., Kramer, J.M., Stinchcomb, D. & Ambros, V. Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10, 3959-3970 (1991).
27. Garigan, D. et al. Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. Genetics 161, 1101-1112 (2002).