A powerful new quantitative genetics platform, combining caenorhabditis elegans high-throughput fitness assays with a large collection of recombinant strains

G3: Genes, Genomes, Genetics

Volumn 5, Issue 5, 2015, Pages 911-920

  Andersen, Erik C ^a   Shimko, Tyler C ^a   Crissman, Jonathan R ^b,d   Ghosh, Rajarshi ^b,e   Bloom, Joshua S ^c   Seidel, Hannah S ^b,f   Gerke, Justin P ^b,g   Kruglyak, Leonid ^c,h  

^a NORTHWESTERN UNIVERSITY   (United States)

^b PRINCETON UNIVERSITY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF WISCONSIN MADISON   (United States)

^g DUPONT COMPANY   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

C. elegans; Fitness assays; High throughput phenotyping; QTL mapping

Indexed keywords

NEUROPEPTIDE RECEPTOR; NEUROPEPTIDE RECEPTOR 1; UNCLASSIFIED DRUG; HERBICIDE;

ADVANCED INTERCROSS LINE; ARTICLE; ASSAY; BODY SIZE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; FERTILITY; GENE FREQUENCY; GENE IDENTIFICATION; GENE LOCUS; GENE MAPPING; GENETIC INCOMPATIBILITY; GENETIC LINKAGE; GENETIC VARIABILITY; GENOTYPE; HIDDEN MARKOV MODEL; HIGH THROUGHPUT FITNESS ASSAY; NONHUMAN; PHENOTYPE; QUANTITATIVE GENETICS; QUANTITATIVE TRAIT LOCUS; RECOMBINANT INBRED STRAIN; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; BIOLOGICAL MODEL; CHROMOSOMAL MAPPING; DRUG EFFECTS; GENETIC RECOMBINATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; QUANTITATIVE TRAIT; REPRODUCTIVE FITNESS;

BACTERIA (MICROORGANISMS); CAENORHABDITIS ELEGANS;

ANIMALS; CAENORHABDITIS ELEGANS; CHROMOSOME MAPPING; GENETIC FITNESS; GENETIC LINKAGE; HERBICIDES; MODELS, GENETIC; PHENOTYPE; QUANTITATIVE TRAIT LOCI; QUANTITATIVE TRAIT, HERITABLE; RECOMBINATION, GENETIC;

EID: 84929862501     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.115.017178     Document Type: Article

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