Erratum: γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation (Cell (2016) 166(6) (1485–1499.e15), (S0092867416309965), (10.1016/j.cell.2016.07.046));γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation

Cell

Volumn 166, Issue 6, 2016, Pages 1485-1499.e15

  Daley, Donnele ^a   Zambirinis, Constantinos Pantelis ^a   Seifert, Lena ^a   Akkad, Neha ^a   Mohan, Navyatha ^a   Werba, Gregor ^a   Barilla, Rocky ^a   Torres Hernandez, Alejandro ^a   Hundeyin, Mautin ^a   Mani, Vishnu Raj Kumar ^a   Avanzi, Antonina ^a   Tippens, Daniel ^a   Narayanan, Rajkishen ^a   Jang, Jung Eun ^a   Newman, Elliot ^a   Pillarisetty, Venu Gopal ^b   Dustin, Michael Loran ^a,c   Bar Sagi, Dafna ^a   Hajdu, Cristina ^a   Miller, George ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

cancer; checkpoint ligands; Kras

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; ECALECTIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; PROGRAMMED DEATH 1 LIGAND 1; TUMOR NECROSIS FACTOR; CHEMOKINE; LIGAND;

ADOPTIVE TRANSFER; ALPHA BETA T CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INTERACTION; CELLS; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPITHELIUM CELL; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GAMMA DELTA T LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNOGENICITY; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR GROWTH; TUMOR IMMUNITY; TUMOR MICROENVIRONMENT; TUMOR SUPPRESSOR GENE; ADAPTIVE IMMUNITY; ANIMAL; C57BL MOUSE; CELL CULTURE; IMMUNOLOGY; PANCREAS CARCINOMA; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADAPTIVE IMMUNITY; ANIMALS; CARCINOGENESIS; CARCINOMA, PANCREATIC DUCTAL; CELLS, CULTURED; CHEMOKINES; EPITHELIAL CELLS; FEMALE; HUMANS; LIGANDS; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED C57BL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TUMOR MICROENVIRONMENT;

EID: 84986296840     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2020.10.041     Document Type: Erratum

References (44)

1. Andrén-Sandberg, A., Dervenis, C., Lowenfels, B., Etiologic links between chronic pancreatitis and pancreatic cancer. Scand. J. Gastroenterol. 32 (1997), 97–103.
2. Bayne, L.J., Beatty, G.L., Jhala, N., Clark, C.E., Rhim, A.D., Stanger, B.Z., Vonderheide, R.H., Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer. Cancer Cell 21 (2012), 822–835.
3. Bedrosian, A.S., Nguyen, A.H., Hackman, M., Connolly, M.K., Malhotra, A., Ibrahim, J., Cieza-Rubio, N.E., Henning, J.R., Barilla, R., Rehman, A., et al. Dendritic cells promote pancreatic viability in mice with acute pancreatitis. Gastroenterology 141 (2011), 1915–1926.
4. Clark, C.E., Hingorani, S.R., Mick, R., Combs, C., Tuveson, D.A., Vonderheide, R.H., Dynamics of the immune reaction to pancreatic cancer from inception to invasion. Cancer Res. 67 (2007), 9518–9527.
5. Coffelt, S.B., Kersten, K., Doornebal, C.W., Weiden, J., Vrijland, K., Hau, C.S., Verstegen, N.J., Ciampricotti, M., Hawinkels, L.J., Jonkers, J., et al. 17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis. Nature 522 (2015), 345–348.
6. Connolly, M.K., Mallen-St Clair, J., Bedrosian, A.S., Malhotra, A., Vera, V., Ibrahim, J., Henning, J., Pachter, H.L., Bar-Sagi, D., Frey, A.B., Miller, G., Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor. J. Leukoc. Biol. 87 (2010), 713–725.
7. Cordova, A., Toia, F., La Mendola, C., Orlando, V., Meraviglia, S., Rinaldi, G., Todaro, M., Cicero, G., Zichichi, L., Donni, P.L., et al. Characterization of human γδ T lymphocytes infiltrating primary malignant melanomas. PLoS ONE, 7, 2012, e49878.
8. De Monte, L., Reni, M., Tassi, E., Clavenna, D., Papa, I., Recalde, H., Braga, M., Di Carlo, V., Doglioni, C., Protti, M.P., Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer. J. Exp. Med. 208 (2011), 469–478.
9. Feig, C., Jones, J.O., Kraman, M., Wells, R.J., Deonarine, A., Chan, D.S., Connell, C.M., Roberts, E.W., Zhao, Q., Caballero, O.L., et al. Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer. Proc. Natl. Acad. Sci. USA 110 (2013), 20212–20217.
10. Fukunaga, A., Miyamoto, M., Cho, Y., Murakami, S., Kawarada, Y., Oshikiri, T., Kato, K., Kurokawa, T., Suzuoki, M., Nakakubo, Y., et al. CD8+ tumor-infiltrating lymphocytes together with CD4+ tumor-infiltrating lymphocytes and dendritic cells improve the prognosis of patients with pancreatic adenocarcinoma. Pancreas 28 (2004), e26–e31.
11. Gao, Y., Yang, W., Pan, M., Scully, E., Girardi, M., Augenlicht, L.H., Craft, J., Yin, Z., Gamma delta T cells provide an early source of interferon gamma in tumor immunity. J. Exp. Med. 198 (2003), 433–442.
12. Girardi, M., Oppenheim, D.E., Steele, C.R., Lewis, J.M., Glusac, E., Filler, R., Hobby, P., Sutton, B., Tigelaar, R.E., Hayday, A.C., Regulation of cutaneous malignancy by gammadelta T cells. Science 294 (2001), 605–609.
13. Goggins, M., Shekher, M., Turnacioglu, K., Yeo, C.J., Hruban, R.H., Kern, S.E., Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas. Cancer Res. 58 (1998), 5329–5332.
14. Greco, S.H., Tomkötter, L., Vahle, A.K., Rokosh, R., Avanzi, A., Mahmood, S.K., Deutsch, M., Alothman, S., Alqunaibit, D., Ochi, A., et al. TGF-β blockade reduces mortality and metabolic changes in a validated murine model of pancreatic cancer cachexia. PLoS ONE, 10, 2015, e0132786.
15. Guerra, C., Schuhmacher, A.J., Cañamero, M., Grippo, P.J., Verdaguer, L., Pérez-Gallego, L., Dubus, P., Sandgren, E.P., Barbacid, M., Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice. Cancer Cell 11 (2007), 291–302.
16. Hao, J., Dong, S., Xia, S., He, W., Jia, H., Zhang, S., Wei, J., O'Brien, R.L., Born, W.K., Wu, Z., et al. Regulatory role of Vγ1 γδ T cells in tumor immunity through IL-4 production. J. Immunol. 187 (2011), 4979–4986.
17. Hingorani, S.R., Petricoin, E.F., Maitra, A., Rajapakse, V., King, C., Jacobetz, M.A., Ross, S., Conrads, T.P., Veenstra, T.D., Hitt, B.A., et al. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 4 (2003), 437–450.
18. Hruban, R.H., Adsay, N.V., Albores-Saavedra, J., Compton, C., Garrett, E.S., Goodman, S.N., Kern, S.E., Klimstra, D.S., Klöppel, G., Longnecker, D.S., et al. Pancreatic intraepithelial neoplasia: A new nomenclature and classification system for pancreatic duct lesions. Am. J. Surg. Pathol. 25 (2001), 579–586.
19. Izumi, T., Kondo, M., Takahashi, T., Fujieda, N., Kondo, A., Tamura, N., Murakawa, T., Nakajima, J., Matsushita, H., Kakimi, K., Ex vivo characterization of γδ T-cell repertoire in patients after adoptive transfer of Vγ9Vδ2 T cells expressing the interleukin-2 receptor β-chain and the common γ-chain. Cytotherapy 15 (2013), 481–491.
20. Joyce, J.A., Fearon, D.T., T cell exclusion, immune privilege, and the tumor microenvironment. Science 348 (2015), 74–80.
21. Kang, N., Tang, L., Li, X., Wu, D., Li, W., Chen, X., Cui, L., Ba, D., He, W., Identification and characterization of Foxp3(+) gammadelta T cells in mouse and human. Immunol. Lett. 125 (2009), 105–113.
22. Kunzmann, V., Smetak, M., Kimmel, B., Weigang-Koehler, K., Goebeler, M., Birkmann, J., Becker, J., Schmidt-Wolf, I.G., Einsele, H., Wilhelm, M., Tumor-promoting versus tumor-antagonizing roles of γδ T cells in cancer immunotherapy: Results from a prospective phase I/II trial. J. Immunother. 35 (2012), 205–213.
23. Lança, T., Silva-Santos, B., The split nature of tumor-infiltrating leukocytes: Implications for cancer surveillance and immunotherapy. OncoImmunology 1 (2012), 717–725.
24. Liou, G.Y., Döppler, H., Necela, B., Edenfield, B., Zhang, L., Dawson, D.W., Storz, P., Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions. Cancer Discov. 5 (2015), 52–63.
25. Ma, S., Cheng, Q., Cai, Y., Gong, H., Wu, Y., Yu, X., Shi, L., Wu, D., Dong, C., Liu, H., IL-17A produced by γδ T cells promotes tumor growth in hepatocellular carcinoma. Cancer Res. 74 (2014), 1969–1982.
26. McAllister, F., Bailey, J.M., Alsina, J., Nirschl, C.J., Sharma, R., Fan, H., Rattigan, Y., Roeser, J.C., Lankapalli, R.H., Zhang, H., et al. Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia. Cancer Cell 25 (2014), 621–637.
27. Nomi, T., Sho, M., Akahori, T., Hamada, K., Kubo, A., Kanehiro, H., Nakamura, S., Enomoto, K., Yagita, H., Azuma, M., et al. Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer. Clin. Cancer Res. 13 (2007), 2151–2157.
28. Oberg, H.H., Peipp, M., Kellner, C., Sebens, S., Krause, S., Petrick, D., Adam-Klages, S., Röcken, C., Becker, T., Vogel, I., et al. Novel bispecific antibodies increase γδ T-cell cytotoxicity against pancreatic cancer cells. Cancer Res. 74 (2014), 1349–1360.
29. Ochi, A., Graffeo, C.S., Zambirinis, C.P., Rehman, A., Hackman, M., Fallon, N., Barilla, R.M., Henning, J.R., Jamal, M., Rao, R., et al. Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans. J. Clin. Invest. 122 (2012), 4118–4129.
30. Ochi, A., Nguyen, A.H., Bedrosian, A.S., Mushlin, H.M., Zarbakhsh, S., Barilla, R., Zambirinis, C.P., Fallon, N.C., Rehman, A., Pylayeva-Gupta, Y., et al. MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells. J. Exp. Med. 209 (2012), 1671–1687.
31. Peng, G., Wang, H.Y., Peng, W., Kiniwa, Y., Seo, K.H., Wang, R.F., Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway. Immunity 27 (2007), 334–348.
32. Pylayeva-Gupta, Y., Lee, K.E., Hajdu, C.H., Miller, G., Bar-Sagi, D., Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia. Cancer Cell 21 (2012), 836–847.
33. Rehman, A., Hemmert, K.C., Ochi, A., Jamal, M., Henning, J.R., Barilla, R., Quesada, J.P., Zambirinis, C.P., Tang, K., Ego-Osuala, M., et al. Role of fatty-acid synthesis in dendritic cell generation and function. J. Immunol. 190 (2013), 4640–4649.
34. Sallusto, F., Geginat, J., Lanzavecchia, A., Central memory and effector memory T cell subsets: Function, generation, and maintenance. Annu. Rev. Immunol. 22 (2004), 745–763.
35. Seifert, L., Werba, G., Tiwari, S., Giao Ly, N.N., Alothman, S., Alqunaibit, D., Avanzi, A., Barilla, R., Daley, D., Greco, S.H., et al. The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression. Nature 532 (2016), 245–249.
36. Sharma, P., Allison, J.P., The future of immune checkpoint therapy. Science 348 (2015), 56–61.
37. Todaro, M., D'Asaro, M., Caccamo, N., Iovino, F., Francipane, M.G., Meraviglia, S., Orlando, V., La Mendola, C., Gulotta, G., Salerno, A., et al. Efficient killing of human colon cancer stem cells by gammadelta T lymphocytes. J. Immunol. 182 (2009), 7287–7296.
38. Wu, P., Wu, D., Ni, C., Ye, J., Chen, W., Hu, G., Wang, Z., Wang, C., Zhang, Z., Xia, W., et al. γδT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer. Immunity 40 (2014), 785–800.
39. Wu, H.H., Hwang-Verslues, W.W., Lee, W.H., Huang, C.K., Wei, P.C., Chen, C.L., Shew, J.Y., Lee, E.Y., Jeng, Y.M., Tien, Y.W., et al. Targeting IL-17B-IL-17RB signaling with an anti-IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines. J. Exp. Med. 212 (2015), 333–349.
40. Yadav, D., Lowenfels, A.B., The epidemiology of pancreatitis and pancreatic cancer. Gastroenterology 144 (2013), 1252–1261.
41. Yang, J., Sanderson, N.S., Wawrowsky, K., Puntel, M., Castro, M.G., Lowenstein, P.R., Kupfer-type immunological synapse characteristics do not predict anti-brain tumor cytolytic T-cell function in vivo. Proc. Natl. Acad. Sci. USA 107 (2010), 4716–4721.
42. Zambirinis, C.P., Levie, E., Nguy, S., Avanzi, A., Barilla, R., Xu, Y., Seifert, L., Daley, D., Greco, S.H., Deutsch, M., et al. TLR9 ligation in pancreatic stellate cells promotes tumorigenesis. J. Exp. Med. 212 (2015), 2077–2094.
43. Zheng, L., Xue, J., Jaffee, E.M., Habtezion, A., Role of immune cells and immune-based therapies in pancreatitis and pancreatic ductal adenocarcinoma. Gastroenterology 144 (2013), 1230–1240.
44. Zhu, Y., Knolhoff, B.L., Meyer, M.A., Nywening, T.M., West, B.L., Luo, J., Wang-Gillam, A., Goedegebuure, S.P., Linehan, D.C., DeNardo, D.G., CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models. Cancer Res. 74 (2014), 5057–5069.