Inhibition of AMP-activated protein kinase alleviates focal cerebral ischemia injury in mice: Interference with mTOR and autophagy

Brain Research

Volumn 1650, Issue , 2016, Pages 103-111

  Fu, Le ^a   Huang, Liang ^a   Cao, Chunshui ^a   Yin, Qin ^a   Liu, Jian ^a  

^a NANCHANG UNIVERSITY   (China)

Author keywords

AMPK; Autophagy; Cerebral ischemia; MTOR

Indexed keywords

BECLIN 1; COMPOUND C; DORSOMORPHIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN; PROTEIN LC3; UNCLASSIFIED DRUG; MTOR PROTEIN, MOUSE; PROTEIN KINASE INHIBITOR; TARGET OF RAPAMYCIN KINASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BRAIN CORTEX; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PROTECTION; BRAIN WATER; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROLOGIC DISEASE; NISSL SUBSTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHAM PROCEDURE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BRAIN; BRAIN INJURIES; CEREBROVASCULAR ACCIDENT; DISEASE MODEL; DRUG EFFECTS; ISCHEMIA; METABOLISM; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AUTOPHAGY; BRAIN; BRAIN INJURIES; BRAIN ISCHEMIA; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; ISCHEMIA; MALE; MICE; MICE, INBRED BALB C; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION; STROKE; TOR SERINE-THREONINE KINASES;

EID: 84986293363     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2016.08.035     Document Type: Article

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