-
1
-
-
85020249099
-
CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2008-2012
-
Oct
-
Q.T.Ostrom, H.Gittleman, J.Fulop, et al. CBTRUS statistical report:primary brain and central nervous system tumors diagnosed in the United States in 2008-2012. Neuro Oncol. 2015 Oct;17 Suppl 4:iv1–iv62. doi:10.1093/neuonc/nov189.
-
(2015)
Neuro Oncol
, vol.17 Suppl 4
, pp. iv1-iv62
-
-
Ostrom, Q.T.1
Gittleman, H.2
Fulop, J.3
-
2
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
R.Stupp, W.P.Mason, M.J.van den Bent, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352(10):987–996. doi:10.1056/NEJMoa043330.
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
-
3
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Aug
-
F.S.Hodi, S.J.O’Day, D.F.McDermott, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010 Aug 19;363(8):711–723.
-
(2010)
N Engl J Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O’Day, S.J.2
McDermott, D.F.3
-
4
-
-
84925222119
-
Nivolumab in previously untreated melanoma without BRAF mutation
-
Jan
-
C.Robert, G.V.Long, B.Brady, et al. Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med. 2015 Jan 22;372(4):320–330.
-
(2015)
N Engl J Med
, vol.372
, Issue.4
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
-
5
-
-
84908354848
-
Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
-
Sep
-
C.Robert, A.Ribas, J.D.Wolchok, et al. Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma:a randomised dose-comparison cohort of a phase 1 trial. Lancet. 2014 Sep 20;384(9948):1109–1117.
-
(2014)
Lancet
, vol.384
, Issue.9948
, pp. 1109-1117
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
-
6
-
-
84924809260
-
Nivolumab in NSCLC: latest evidence and clinical potential
-
Mar
-
R.Sundar, B.C.Cho, J.R.Brahmer, et al. Nivolumab in NSCLC:latest evidence and clinical potential. Ther Adv Med Oncol. 2015 Mar;7(2):85–96. doi:10.1177/1758834014567470.
-
(2015)
Ther Adv Med Oncol
, vol.7
, Issue.2
, pp. 85-96
-
-
Sundar, R.1
Cho, B.C.2
Brahmer, J.R.3
-
7
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Jul
-
P.W.Kantoff, C.S.Higano, N.D.Shore, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med. 2010 Jul 29;363(5):411–422.
-
(2010)
N Engl J Med
, vol.363
, Issue.5
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
8
-
-
84908073316
-
Chimeric antigen receptor T cells for sustained remissions in leukemia
-
Oct
-
S.L.Maude, N.Frey, P.A.Shaw, et al. Chimeric antigen receptor T cells for sustained remissions in leukemia. N Engl J Med. 2014 Oct 16;371(16):1507–1517.
-
(2014)
N Engl J Med
, vol.371
, Issue.16
, pp. 1507-1517
-
-
Maude, S.L.1
Frey, N.2
Shaw, P.A.3
-
9
-
-
84876325876
-
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
-
Apr
-
S.A.Grupp, M.Kalos, D.Barrett, et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N Engl J Med. 2013 Apr 18;368(16):1509–1518.
-
(2013)
N Engl J Med
, vol.368
, Issue.16
, pp. 1509-1518
-
-
Grupp, S.A.1
Kalos, M.2
Barrett, D.3
-
10
-
-
0029845753
-
Combined chemokine and cytokine gene transfer enhances antitumor immunity
-
Oct
-
D.Dilloo, K.Bacon, W.Holden, et al. Combined chemokine and cytokine gene transfer enhances antitumor immunity. Nat Med. 1996 Oct;2(10):1090–1095.
-
(1996)
Nat Med
, vol.2
, Issue.10
, pp. 1090-1095
-
-
Dilloo, D.1
Bacon, K.2
Holden, W.3
-
11
-
-
40149090821
-
Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas
-
H.Okada, F.S.Lieberman, K.A.Walter, et al. Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas. J Transl Med. 2007;5:67. doi:10.1186/1479-5876-5-67.
-
(2007)
J Transl Med
, vol.5
, pp. 67
-
-
Okada, H.1
Lieberman, F.S.2
Walter, K.A.3
-
12
-
-
0034851134
-
Phase 1 clinical trial of irradiated autologous melanoma cells adenovirally transduced with human GM-CSF gene
-
Sep
-
M.Kusumoto, S.Umeda, A.Ikubo, et al. Phase 1 clinical trial of irradiated autologous melanoma cells adenovirally transduced with human GM-CSF gene. Cancer Immunol Immunother. 2001 Sep;50(7):373–381.
-
(2001)
Cancer Immunol Immunother
, vol.50
, Issue.7
, pp. 373-381
-
-
Kusumoto, M.1
Umeda, S.2
Ikubo, A.3
-
13
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
-
Apr
-
G.Dranoff, E.Jaffee, A.Lazenby, et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA. 1993 Apr 15;90(8):3539–3543.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.8
, pp. 3539-3543
-
-
Dranoff, G.1
Jaffee, E.2
Lazenby, A.3
-
14
-
-
0038826485
-
Vaccination of women with metastatic breast cancer, using a costimulatory gene (CD80)-modified, HLA-A2-matched, allogeneic, breast cancer cell line: clinical and immunological results
-
Jul
-
A.Dols, J.W.Smith2nd, S.L.Meijer, et al. Vaccination of women with metastatic breast cancer, using a costimulatory gene (CD80)-modified, HLA-A2-matched, allogeneic, breast cancer cell line:clinical and immunological results. Hum Gene Ther. 2003 Jul 20;14(11):1117–1123.
-
(2003)
Hum Gene Ther
, vol.14
, Issue.11
, pp. 1117-1123
-
-
Dols, A.1
Smith, J.W.2
Meijer, S.L.3
-
15
-
-
0032991779
-
Effective cytokine gene therapy against an intracranial glioma using a retrovirally transduced IL-4 plus HSVtk tumor vaccine
-
Feb
-
H.Okada, K.M.Giezeman-Smits, H.Tahara, et al. Effective cytokine gene therapy against an intracranial glioma using a retrovirally transduced IL-4 plus HSVtk tumor vaccine. Gene Ther. 1999 Feb;6(2):219–226. doi:10.1038/sj.gt.3300798.
-
(1999)
Gene Ther
, vol.6
, Issue.2
, pp. 219-226
-
-
Okada, H.1
Giezeman-Smits, K.M.2
Tahara, H.3
-
16
-
-
0034886741
-
Cytokine gene therapy of gliomas: effective induction of therapeutic immunity to intracranial tumors by peripheral immunization with interleukin-4 transduced glioma cells
-
Aug
-
H.Okada, L.Villa, J.Attanucci, et al. Cytokine gene therapy of gliomas:effective induction of therapeutic immunity to intracranial tumors by peripheral immunization with interleukin-4 transduced glioma cells. Gene Ther. 2001 Aug;8(15):1157–1166. doi:10.1038/sj.gt.3301496.
-
(2001)
Gene Ther
, vol.8
, Issue.15
, pp. 1157-1166
-
-
Okada, H.1
Villa, L.2
Attanucci, J.3
-
17
-
-
18744382422
-
Interleukin-4 gene transduced tumor cells promote a potent tumor-specific Th1-type response in cooperation with interferon-alpha transduction
-
J.Eguchi, K.Hiroishi, S.Ishii, et al. Interleukin-4 gene transduced tumor cells promote a potent tumor-specific Th1-type response in cooperation with interferon-alpha transduction. GeneTher. 2005;12:733–741.
-
(2005)
GeneTher
, vol.12
, pp. 733-741
-
-
Eguchi, J.1
Hiroishi, K.2
Ishii, S.3
-
18
-
-
23444439371
-
Delivery of dendritic cells engineered to secrete IFN-{alpha} into central nervous system tumors enhances the efficacy of peripheral tumor cell vaccines: dependence on apoptotic pathways
-
N.Kuwashima, F.Nishimura, J.Eguchi, et al. Delivery of dendritic cells engineered to secrete IFN-{alpha} into central nervous system tumors enhances the efficacy of peripheral tumor cell vaccines:dependence on apoptotic pathways. J Immunol. 2005;175(4):2730–2740. doi:10.4049/jimmunol.175.4.2730.
-
(2005)
J Immunol
, vol.175
, Issue.4
, pp. 2730-2740
-
-
Kuwashima, N.1
Nishimura, F.2
Eguchi, J.3
-
19
-
-
84907327423
-
Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma
-
Sep
-
E.Ishikawa, Y.Muragaki, T.Yamamoto, et al. Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma. J Neurosurg. 2014 Sep;121(3):543–553. doi:10.3171/2014.5.JNS132392.
-
(2014)
J Neurosurg
, vol.121
, Issue.3
, pp. 543-553
-
-
Ishikawa, E.1
Muragaki, Y.2
Yamamoto, T.3
-
20
-
-
84975078327
-
Vaccination with irradiated autologous tumor cells mixed with irradiated GM-K562 cells stimulates antitumor immunity and T lymphocyte activation in patients with recurrent malignant glioma
-
Feb
-
W.T.CurryJr., R.Gorrepati, M.Piesche, et al. Vaccination with irradiated autologous tumor cells mixed with irradiated GM-K562 cells stimulates antitumor immunity and T lymphocyte activation in patients with recurrent malignant glioma. Clin Cancer Res. 2016 Feb 12;22:2885–2896. doi:10.1158/1078-0432.CCR-15-2163.
-
(2016)
Clin Cancer Res
, vol.22
, pp. 2885-2896
-
-
Curry, W.T.1
Gorrepati, R.2
Piesche, M.3
-
21
-
-
79961170539
-
Dendritic cells in cancer immunotherapy: vaccines or autologous transplants?
-
Aug
-
P.Kalinski, H.Edington, H.J.Zeh, et al. Dendritic cells in cancer immunotherapy:vaccines or autologous transplants? Immunol Res. 2011 Aug;50(2–3):235–247. doi:10.1007/s12026-011-8224-z.
-
(2011)
Immunol Res
, vol.50
, Issue.2-3
, pp. 235-247
-
-
Kalinski, P.1
Edington, H.2
Zeh, H.J.3
-
22
-
-
84868033440
-
Immunotherapy with tumor vaccines for the treatment of malignant gliomas
-
Dec
-
D.Ajay, L.Sanchez-Perez, B.D.Choi, et al. Immunotherapy with tumor vaccines for the treatment of malignant gliomas. Curr Drug Discov Technol. 2012 Dec;9(4):237–255.
-
(2012)
Curr Drug Discov Technol
, vol.9
, Issue.4
, pp. 237-255
-
-
Ajay, D.1
Sanchez-Perez, L.2
Choi, B.D.3
-
23
-
-
12444288645
-
Immunotherapy for malignant gliomas: emphasis on strategies of active specific immunotherapy using autologous dendritic cells
-
Jan
-
S.De Vleeschouwer, S.W.Van Gool, F.Van Calenbergh Immunotherapy for malignant gliomas:emphasis on strategies of active specific immunotherapy using autologous dendritic cells. Childs Nerv Syst. 2005 Jan;21(1):7–18. doi:10.1007/s00381-004-0994-3.
-
(2005)
Childs Nerv Syst
, vol.21
, Issue.1
, pp. 7-18
-
-
De Vleeschouwer, S.1
Van Gool, S.W.2
Van Calenbergh, F.3
-
24
-
-
0142089462
-
Treatment of a patient by vaccination with autologous dendritic cells pulsed with allogeneic major histocompatibility complex class I-matched tumor peptides
-
L.M.Liau, K.L.Black, N.A.Martin, et al. Treatment of a patient by vaccination with autologous dendritic cells pulsed with allogeneic major histocompatibility complex class I-matched tumor peptides. Case Report Neurosurg Focus. 2000;9(6):e8.
-
(2000)
Case Report Neurosurg Focus
, vol.9
, Issue.6
, pp. e8
-
-
Liau, L.M.1
Black, K.L.2
Martin, N.A.3
-
25
-
-
0035107548
-
Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell infiltration
-
Feb
-
J.S.Yu, C.J.Wheeler, P.M.Zeltzer, et al. Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell infiltration. Cancer Res. 2001 Feb 1;61(3):842–847.
-
(2001)
Cancer Res
, vol.61
, Issue.3
, pp. 842-847
-
-
Yu, J.S.1
Wheeler, C.J.2
Zeltzer, P.M.3
-
26
-
-
48649096955
-
Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients
-
Jul
-
C.J.Wheeler, K.L.Black, G.Liu, et al. Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients. Cancer Res. 2008 Jul 15;68(14):5955–5964.
-
(2008)
Cancer Res
, vol.68
, Issue.14
, pp. 5955-5964
-
-
Wheeler, C.J.1
Black, K.L.2
Liu, G.3
-
27
-
-
84870985481
-
Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma: results of the HGG-2006 phase I/II trial
-
Nov
-
H.Ardon, S.W.Van Gool, T.Verschuere, et al. Integration of autologous dendritic cell-based immunotherapy in the standard of care treatment for patients with newly diagnosed glioblastoma:results of the HGG-2006 phase I/II trial. Cancer Immunol Immunother. 2012 Nov;61(11):2033–2044. doi:10.1007/s00262-012-1261-1.
-
(2012)
Cancer Immunol Immunother
, vol.61
, Issue.11
, pp. 2033-2044
-
-
Ardon, H.1
Van Gool, S.W.2
Verschuere, T.3
-
28
-
-
79952711945
-
Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy
-
Mar
-
R.M.Prins, H.Soto, V.Konkankit, et al. Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy. Clin Cancer Res. 2011 Mar 15;17(6):1603–1615.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.6
, pp. 1603-1615
-
-
Prins, R.M.1
Soto, H.2
Konkankit, V.3
-
29
-
-
70350448730
-
Brain tumor immunotherapy with type-1 polarizing strategies
-
Sep
-
H.Okada. Brain tumor immunotherapy with type-1 polarizing strategies. Ann NY Acad Sci. 2009 Sep;1174:18–23. doi:10.1111/j.1749-6632.2009.04932.x.
-
(2009)
Ann NY Acad Sci
, vol.1174
, pp. 18-23
-
-
Okada, H.1
-
30
-
-
85016924184
-
Vaccination strategies for neuro-oncology
-
Nov
-
J.H.Sampson, D.A.Mitchell. Vaccination strategies for neuro-oncology. Neuro Oncol. 2015 Nov;17 Suppl 7:vii15–vii25. doi:10.1093/neuonc/nov159.
-
(2015)
Neuro Oncol
, vol.17 Suppl 7
, pp. vii15-vii25
-
-
Sampson, J.H.1
Mitchell, D.A.2
-
31
-
-
84911890607
-
Immunotherapy advances for glioblastoma
-
Nov
-
D.A.Reardon, G.Freeman, C.Wu, et al. Immunotherapy advances for glioblastoma. Neuro-oncology. 2014 Nov;16(11):1441–1458. doi:10.1093/neuonc/nou212.
-
(2014)
Neuro-oncology
, vol.16
, Issue.11
, pp. 1441-1458
-
-
Reardon, D.A.1
Freeman, G.2
Wu, C.3
-
32
-
-
84879066269
-
An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma
-
Jun
-
D.A.Reardon, K.W.Wucherpfennig, G.Freeman, et al. An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma. Expert Rev Vaccines. 2013 Jun;12(6):597–615. doi:10.1586/erv.13.41.• Excellent review providing an updated and comprehensive information on recent immunotherapy approaches for glioblastomas.
-
(2013)
Expert Rev Vaccines
, vol.12
, Issue.6
, pp. 597-615
-
-
Reardon, D.A.1
Wucherpfennig, K.W.2
Freeman, G.3
-
33
-
-
79951978155
-
Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma
-
January
-
H.Okada, P.Kalinski, R.Ueda, et al. Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma. J Clin Oncol. 2011 January 20;29(3):330–336.
-
(2011)
J Clin Oncol
, vol.29
, Issue.3
, pp. 330-336
-
-
Okada, H.1
Kalinski, P.2
Ueda, R.3
-
34
-
-
84872498982
-
Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma
-
Jan
-
S.Phuphanich, C.J.Wheeler, J.D.Rudnick, et al. Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma. Cancer Immunol Immunother. 2013 Jan;62(1):125–135. doi:10.1007/s00262-012-1319-0.
-
(2013)
Cancer Immunol Immunother
, vol.62
, Issue.1
, pp. 125-135
-
-
Phuphanich, S.1
Wheeler, C.J.2
Rudnick, J.D.3
-
35
-
-
0642311904
-
Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells
-
Nov
-
C.L.SlingluffJr., G.R.Petroni, G.V.Yamshchikov, et al. Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells. J Clin Oncol. 2003 Nov 1;21(21):4016–4026.
-
(2003)
J Clin Oncol
, vol.21
, Issue.21
, pp. 4016-4026
-
-
Slingluff, C.L.1
Petroni, G.R.2
Yamshchikov, G.V.3
-
36
-
-
4143103624
-
Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination
-
Aug
-
C.J.Wheeler, A.Das, G.Liu, et al. Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination. Clin Cancer Res. 2004 Aug 15;10(16):5316–5326.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.16
, pp. 5316-5326
-
-
Wheeler, C.J.1
Das, A.2
Liu, G.3
-
37
-
-
84893073441
-
Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: a phase II, single-arm trial
-
Jan
-
O.Bloch, C.A.Crane, Y.Fuks, et al. Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma:a phase II, single-arm trial. Neuro Oncol. 2014 Jan;16(2):274–279. doi:10.1093/neuonc/not203.
-
(2014)
Neuro Oncol
, vol.16
, Issue.2
, pp. 274-279
-
-
Bloch, O.1
Crane, C.A.2
Fuks, Y.3
-
38
-
-
84879112954
-
Profound impairment of adaptive immune responses by alkylating chemotherapy
-
Jun
-
A.J.Litterman, D.M.Zellmer, K.L.Grinnen, et al. Profound impairment of adaptive immune responses by alkylating chemotherapy. J Immunology. 2013 Jun 15;190(12):6259–6268. doi:10.4049/jimmunol.1203539.• A very well designed and considerate study evaluating impacts of chemotherapy on vaccine-reactive T cells in preclinical glioma vaccine models.
-
(2013)
J Immunology
, vol.190
, Issue.12
, pp. 6259-6268
-
-
Litterman, A.J.1
Zellmer, D.M.2
Grinnen, K.L.3
-
39
-
-
84859557807
-
Consensus on the role of human cytomegalovirus in glioblastoma
-
March
-
K.Dziurzynski, S.M.Chang, A.B.Heimberger, et al. Consensus on the role of human cytomegalovirus in glioblastoma. Neuro Oncol. 2012 March 1;14(3):246–255.
-
(2012)
Neuro Oncol
, vol.14
, Issue.3
, pp. 246-255
-
-
Dziurzynski, K.1
Chang, S.M.2
Heimberger, A.B.3
-
40
-
-
0037096733
-
Human cytomegalovirus infection and expression in human malignant glioma
-
C.S.Cobbs, L.Harkins, M.Samanta, et al. Human cytomegalovirus infection and expression in human malignant glioma. Cancer Res. 2002;62(12):3347–3350.
-
(2002)
Cancer Res
, vol.62
, Issue.12
, pp. 3347-3350
-
-
Cobbs, C.S.1
Harkins, L.2
Samanta, M.3
-
41
-
-
84925045090
-
Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients
-
Mar
-
D.A.Mitchell, K.A.Batich, M.D.Gunn, et al. Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients. Nature. 2015 Mar 19;519(7543):366–369. doi:10.1038/nature14320.• An important clinical study demonstrating the role of vaccine-site conditioning by Tetanus Toxoid.
-
(2015)
Nature
, vol.519
, Issue.7543
, pp. 366-369
-
-
Mitchell, D.A.1
Batich, K.A.2
Gunn, M.D.3
-
42
-
-
0025004766
-
Immunotherapy for malignant glioma using human recombinant interleukin-2 and activated autologous lymphocytes. A review of pre-clinical and clinical investigations
-
Apr
-
R.E.Merchant, M.D.Ellison, H.F.Young. Immunotherapy for malignant glioma using human recombinant interleukin-2 and activated autologous lymphocytes. A review of pre-clinical and clinical investigations. J Neurooncol. 1990 Apr;8(2):173–188.
-
(1990)
J Neurooncol
, vol.8
, Issue.2
, pp. 173-188
-
-
Merchant, R.E.1
Ellison, M.D.2
Young, H.F.3
-
43
-
-
84862992119
-
Adoptive cell transfer therapy for malignant gliomas
-
E.Ishikawa, S.Takano, T.Ohno, et al. Adoptive cell transfer therapy for malignant gliomas. Adv Exp Med Biol. 2012;746:109–120. doi:10.1007/978-1-4614-3146-6_9.
-
(2012)
Adv Exp Med Biol
, vol.746
, pp. 109-120
-
-
Ishikawa, E.1
Takano, S.2
Ohno, T.3
-
44
-
-
0029090362
-
Phase III randomized trial of interleukin-2 with or without lymphokine-activated killer cells in the treatment of patients with advanced renal cell carcinoma
-
Sep
-
T.M.Law, R.J.Motzer, M.Mazumdar, et al. Phase III randomized trial of interleukin-2 with or without lymphokine-activated killer cells in the treatment of patients with advanced renal cell carcinoma. Cancer. 1995 Sep 1;76(5):824–832.
-
(1995)
Cancer
, vol.76
, Issue.5
, pp. 824-832
-
-
Law, T.M.1
Motzer, R.J.2
Mazumdar, M.3
-
45
-
-
65949111530
-
Expansion of highly cytotoxic human natural killer cells for cancer cell therapy
-
May
-
H.Fujisaki, H.Kakuda, N.Shimasaki, et al. Expansion of highly cytotoxic human natural killer cells for cancer cell therapy. Cancer Res. 2009 May 1;69(9):4010–4017.
-
(2009)
Cancer Res
, vol.69
, Issue.9
, pp. 4010-4017
-
-
Fujisaki, H.1
Kakuda, H.2
Shimasaki, N.3
-
46
-
-
77953404092
-
Safety analysis of ex vivo-expanded NK and NK-like T cells administered to cancer patients: a phase I clinical study
-
Sep
-
L.Barkholt, E.Alici, R.Conrad, et al. Safety analysis of ex vivo-expanded NK and NK-like T cells administered to cancer patients:a phase I clinical study. Immunotherapy. 2009 Sep;1(5):753–764. doi:10.2217/imt.09.47.
-
(2009)
Immunotherapy
, vol.1
, Issue.5
, pp. 753-764
-
-
Barkholt, L.1
Alici, E.2
Conrad, R.3
-
47
-
-
84949544206
-
The application of natural killer cell immunotherapy for the treatment of cancer
-
K.Rezvani, R.H.Rouce. The application of natural killer cell immunotherapy for the treatment of cancer. Front Immunol. 2015;6:578. doi:10.3389/fimmu.2015.00578.
-
(2015)
Front Immunol
, vol.6
, pp. 578
-
-
Rezvani, K.1
Rouce, R.H.2
-
48
-
-
0024592554
-
Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system
-
Apr
-
V.Groh, S.Porcelli, M.Fabbi, et al. Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system. J Exp Med. 1989 Apr 1;169(4):1277–1294.
-
(1989)
J Exp Med
, vol.169
, Issue.4
, pp. 1277-1294
-
-
Groh, V.1
Porcelli, S.2
Fabbi, M.3
-
49
-
-
33744501811
-
Activated gammadelta T cells express the natural cytotoxicity receptor natural killer p 44 and show cytotoxic activity against myeloma cells
-
Jun
-
M.von Lilienfeld-Toal, J.Nattermann, G.Feldmann, et al. Activated gammadelta T cells express the natural cytotoxicity receptor natural killer p 44 and show cytotoxic activity against myeloma cells. Clin Exp Immunol. 2006 Jun;144(3):528–533. doi:10.1111/j.1365-2249.2006.03078.x.
-
(2006)
Clin Exp Immunol
, vol.144
, Issue.3
, pp. 528-533
-
-
von Lilienfeld-Toal, M.1
Nattermann, J.2
Feldmann, G.3
-
50
-
-
0035914134
-
Regulation of cutaneous malignancy by gammadelta T cells
-
Oct
-
M.Girardi, D.E.Oppenheim, C.R.Steele, et al. Regulation of cutaneous malignancy by gammadelta T cells. Science. 2001 Oct 19;294(5542):605–609.
-
(2001)
Science
, vol.294
, Issue.5542
, pp. 605-609
-
-
Girardi, M.1
Oppenheim, D.E.2
Steele, C.R.3
-
51
-
-
84907491837
-
Activating and propagating polyclonal gamma delta T cells with broad specificity for malignancies
-
Nov
-
D.C.Deniger, S.N.Maiti, T.Mi, et al. Activating and propagating polyclonal gamma delta T cells with broad specificity for malignancies. Clin Cancer Res. 2014 Nov 15;20(22):5708–5719.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.22
, pp. 5708-5719
-
-
Deniger, D.C.1
Maiti, S.N.2
Mi, T.3
-
52
-
-
80052446521
-
Clinical evaluation of autologous gamma delta T cell-based immunotherapy for metastatic solid tumours
-
Sep
-
A.J.Nicol, H.Tokuyama, S.R.Mattarollo, et al. Clinical evaluation of autologous gamma delta T cell-based immunotherapy for metastatic solid tumours. Br J Cancer. 2011 Sep 6;105(6):778–786.
-
(2011)
Br J Cancer
, vol.105
, Issue.6
, pp. 778-786
-
-
Nicol, A.J.1
Tokuyama, H.2
Mattarollo, S.R.3
-
53
-
-
70349593630
-
Gammadelta T cells as immune effectors against high-grade gliomas
-
L.S.LambJr. Gammadelta T cells as immune effectors against high-grade gliomas. Immunol Res. 2009;45(1):85–95. doi:10.1007/s12026-009-8114-9.
-
(2009)
Immunol Res
, vol.45
, Issue.1
, pp. 85-95
-
-
Lamb, L.S.1
-
54
-
-
78651291782
-
Preclinical evaluation of ex vivo expanded/activated gammadelta T cells for immunotherapy of glioblastoma multiforme
-
Jan
-
N.L.Bryant, G.Y.Gillespie, R.D.Lopez, et al. Preclinical evaluation of ex vivo expanded/activated gammadelta T cells for immunotherapy of glioblastoma multiforme. J Neurooncol. 2011 Jan;101(2):179–188. doi:10.1007/s11060-010-0245-2.
-
(2011)
J Neurooncol
, vol.101
, Issue.2
, pp. 179-188
-
-
Bryant, N.L.1
Gillespie, G.Y.2
Lopez, R.D.3
-
55
-
-
84938417661
-
The safety of allogeneic innate lymphocyte therapy for glioma patients with prior cranial irradiation
-
May
-
L.Pereboeva, L.Harkins, S.Wong, et al. The safety of allogeneic innate lymphocyte therapy for glioma patients with prior cranial irradiation. Cancer Immunol Immunother. 2015 May;64(5):551–562. doi:10.1007/s00262-015-1662-z.
-
(2015)
Cancer Immunol Immunother
, vol.64
, Issue.5
, pp. 551-562
-
-
Pereboeva, L.1
Harkins, L.2
Wong, S.3
-
56
-
-
84872260923
-
Engineered drug resistant gammadelta T cells kill glioblastoma cell lines during a chemotherapy challenge: a strategy for combining chemo- and immunotherapy
-
L.S.LambJr., J.Bowersock, A.Dasgupta, et al. Engineered drug resistant gammadelta T cells kill glioblastoma cell lines during a chemotherapy challenge:a strategy for combining chemo- and immunotherapy. PLoS One. 2013;8(1):e51805. doi:10.1371/journal.pone.0051805.
-
(2013)
PLoS One
, vol.8
, Issue.1
, pp. e51805
-
-
Lamb, L.S.1
Bowersock, J.2
Dasgupta, A.3
-
57
-
-
84928759208
-
Adoptive cell transfer as personalized immunotherapy for human cancer
-
Apr
-
S.A.Rosenberg, N.P.Restifo. Adoptive cell transfer as personalized immunotherapy for human cancer. Science. 2015 Apr 3;348(6230):62–68. doi:10.1126/science.aaa4967.•• An updated, comprehensive and insightful review on adoptive cell transfer approach for cancer.
-
(2015)
Science
, vol.348
, Issue.6230
, pp. 62-68
-
-
Rosenberg, S.A.1
Restifo, N.P.2
-
58
-
-
0026521970
-
Treatment of murine primary brain tumors with systemic interleukin-2 and tumor-infiltrating lymphocytes
-
Mar
-
S.C.Saris, P.Spiess, D.M.Lieberman, et al. Treatment of murine primary brain tumors with systemic interleukin-2 and tumor-infiltrating lymphocytes. J Neurosurg. 1992 Mar;76(3):513–519. doi:10.3171/jns.1992.76.3.0513.
-
(1992)
J Neurosurg
, vol.76
, Issue.3
, pp. 513-519
-
-
Saris, S.C.1
Spiess, P.2
Lieberman, D.M.3
-
59
-
-
0033506158
-
Pilot study of local autologous tumor infiltrating lymphocytes for the treatment of recurrent malignant gliomas
-
K.B.Quattrocchi, C.H.Miller, S.Cush, et al. Pilot study of local autologous tumor infiltrating lymphocytes for the treatment of recurrent malignant gliomas. J Neurooncol. 1999;45(2):141–157.
-
(1999)
J Neurooncol
, vol.45
, Issue.2
, pp. 141-157
-
-
Quattrocchi, K.B.1
Miller, C.H.2
Cush, S.3
-
60
-
-
84957588938
-
Intrathecal administration of tumor-infiltrating lymphocytes is well tolerated in a patient with leptomeningeal disease from metastatic melanoma: a case report
-
Nov
-
I.C.Glitza, C.Haymaker, C.Bernatchez, et al. Intrathecal administration of tumor-infiltrating lymphocytes is well tolerated in a patient with leptomeningeal disease from metastatic melanoma:a case report. Cancer Immunol Res. 2015 Nov;3(11):1201–1206. doi:10.1158/2326-6066.CIR-15-0071.
-
(2015)
Cancer Immunol Res
, vol.3
, Issue.11
, pp. 1201-1206
-
-
Glitza, I.C.1
Haymaker, C.2
Bernatchez, C.3
-
61
-
-
0025012845
-
Patterns of human tumor-infiltrating lymphocytes in 120 human cancers
-
Feb
-
C.M.Balch, L.B.Riley, Y.J.Bae, et al. Patterns of human tumor-infiltrating lymphocytes in 120 human cancers. Arch Surg. 1990 Feb;125(2):200–205.
-
(1990)
Arch Surg
, vol.125
, Issue.2
, pp. 200-205
-
-
Balch, C.M.1
Riley, L.B.2
Bae, Y.J.3
-
62
-
-
0031832638
-
Systemic T cell adoptive immunotherapy of malignant gliomas
-
Jul
-
G.E.Plautz, G.H.Barnett, D.W.Miller, et al. Systemic T cell adoptive immunotherapy of malignant gliomas. J Neurosurg. 1998 Jul;89(1):42–51. doi:10.3171/jns.1998.89.1.0042.
-
(1998)
J Neurosurg
, vol.89
, Issue.1
, pp. 42-51
-
-
Plautz, G.E.1
Barnett, G.H.2
Miller, D.W.3
-
63
-
-
0034044202
-
T cell adoptive immunotherapy of newly diagnosed gliomas
-
Jun
-
G.E.Plautz, D.W.Miller, G.H.Barnett, et al. T cell adoptive immunotherapy of newly diagnosed gliomas. Clin Cancer Res. 2000 Jun;6(6):2209–2218.
-
(2000)
Clin Cancer Res
, vol.6
, Issue.6
, pp. 2209-2218
-
-
Plautz, G.E.1
Miller, D.W.2
Barnett, G.H.3
-
64
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
R.A.Morgan, M.E.Dudley, J.R.Wunderlich, et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science. 2006;314(5796):126–129. doi:10.1126/science.1129003.
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
-
65
-
-
0034780027
-
Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer
-
Oct
-
T.Stanislawski, R.H.Voss, C.Lotz, et al. Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer. Nat Immunol. 2001 Oct;2(10):962–970. doi:10.1038/ni1001-962.
-
(2001)
Nat Immunol
, vol.2
, Issue.10
, pp. 962-970
-
-
Stanislawski, T.1
Voss, R.H.2
Lotz, C.3
-
66
-
-
70149114880
-
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
-
Jul
-
L.A.Johnson, R.A.Morgan, M.E.Dudley, et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood. 2009 Jul 16;114(3):535–546.
-
(2009)
Blood
, vol.114
, Issue.3
, pp. 535-546
-
-
Johnson, L.A.1
Morgan, R.A.2
Dudley, M.E.3
-
67
-
-
73949155918
-
Development of a Wilms’ tumor antigen-specific T-cell receptor for clinical trials: engineered patient’s T cells can eliminate autologous leukemia blasts in NOD/SCID mice
-
Jan
-
S.A.Xue, L.Gao, S.Thomas, et al. Development of a Wilms’ tumor antigen-specific T-cell receptor for clinical trials:engineered patient’s T cells can eliminate autologous leukemia blasts in NOD/SCID mice. Haematologica. 2010 Jan;95(1):126–134. doi:10.3324/haematol.2009.006486.
-
(2010)
Haematologica
, vol.95
, Issue.1
, pp. 126-134
-
-
Xue, S.A.1
Gao, L.2
Thomas, S.3
-
68
-
-
71549120379
-
Improved expression and reactivity of transduced tumor-specific TCRs in human lymphocytes by specific silencing of endogenous TCR
-
Dec
-
S.Okamoto, J.Mineno, H.Ikeda, et al. Improved expression and reactivity of transduced tumor-specific TCRs in human lymphocytes by specific silencing of endogenous TCR. Cancer Res. 2009 Dec 1;69(23):9003–9011.
-
(2009)
Cancer Res
, vol.69
, Issue.23
, pp. 9003-9011
-
-
Okamoto, S.1
Mineno, J.2
Ikeda, H.3
-
69
-
-
76349107571
-
T cell receptor gene therapy: strategies for optimizing transgenic TCR pairing
-
Feb
-
C.Govers, Z.Sebestyen, M.Coccoris, et al. T cell receptor gene therapy:strategies for optimizing transgenic TCR pairing. Trends Mol Med. 2010 Feb;16(2):77–87. doi:10.1016/j.molmed.2009.12.004.
-
(2010)
Trends Mol Med
, vol.16
, Issue.2
, pp. 77-87
-
-
Govers, C.1
Sebestyen, Z.2
Coccoris, M.3
-
70
-
-
84860611911
-
Genetic engineering with T cell receptors
-
Jun
-
L.Zhang, R.A.Morgan. Genetic engineering with T cell receptors. Adv Drug Deliv Rev. 2012 Jun 1;64(8):756–762.
-
(2012)
Adv Drug Deliv Rev
, vol.64
, Issue.8
, pp. 756-762
-
-
Zhang, L.1
Morgan, R.A.2
-
71
-
-
79952187823
-
T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
-
Mar
-
M.R.Parkhurst, J.C.Yang, R.C.Langan, et al. T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis. Mol Ther. 2011 Mar;19(3):620–626. doi:10.1038/mt.2010.272.
-
(2011)
Mol Ther
, vol.19
, Issue.3
, pp. 620-626
-
-
Parkhurst, M.R.1
Yang, J.C.2
Langan, R.C.3
-
72
-
-
84873991752
-
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
-
Feb
-
R.A.Morgan, N.Chinnasamy, D.Abate-Daga, et al. Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy. J Immunotherapy. 2013 Feb;36(2):133–151. doi:10.1097/CJI.0b013e3182829903.•• A very important report demonstrating the importance of selecting appropriate antigens as well as previously unrecognized levels of susceptibility of the brain to T cell responses.
-
(2013)
J Immunotherapy
, vol.36
, Issue.2
, pp. 133-151
-
-
Morgan, R.A.1
Chinnasamy, N.2
Abate-Daga, D.3
-
73
-
-
84928912377
-
A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response
-
Mar
-
P.F.Robbins, S.H.Kassim, T.L.Tran, et al. A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor:long-term follow-up and correlates with response. Clin Cancer Res. 2015 Mar 1;21(5):1019–1027.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.5
, pp. 1019-1027
-
-
Robbins, P.F.1
Kassim, S.H.2
Tran, T.L.3
-
74
-
-
84938963928
-
NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma
-
Aug
-
A.P.Rapoport, E.A.Stadtmauer, G.K.Binder-Scholl, et al. NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma. Nat Med. 2015 Aug;21(8):914–921. doi:10.1038/nm.3910.
-
(2015)
Nat Med
, vol.21
, Issue.8
, pp. 914-921
-
-
Rapoport, A.P.1
Stadtmauer, E.A.2
Binder-Scholl, G.K.3
-
75
-
-
79956028898
-
Ex vivo gene transfer for improved adoptive immunotherapy of cancer
-
April
-
M.C.Ngo, C.M.Rooney, J.M.Howard, et al. Ex vivo gene transfer for improved adoptive immunotherapy of cancer. Hum Mol Genet. 2011 April 15;20(R1):R93–R99.
-
(2011)
Hum Mol Genet
, vol.20
, Issue.R1
, pp. R93-R99
-
-
Ngo, M.C.1
Rooney, C.M.2
Howard, J.M.3
-
76
-
-
2342534535
-
A functional role for CD28 costimulation in tumor recognition by single-chain receptor-modified T cells
-
M.Moeller, N.M.Haynes, J.A.Trapani, et al. A functional role for CD28 costimulation in tumor recognition by single-chain receptor-modified T cells. Cancer Gene Ther. 2004;11(5):371–379. doi:10.1038/sj.cgt.7700710.
-
(2004)
Cancer Gene Ther
, vol.11
, Issue.5
, pp. 371-379
-
-
Moeller, M.1
Haynes, N.M.2
Trapani, J.A.3
-
77
-
-
33846215917
-
Antibody constructs in cancer therapy - protein engineering strategies to improve exposure in solid tumors
-
Jan
-
R.A.Beckman, L.M.Weiner, H.M.Davis. Antibody constructs in cancer therapy - protein engineering strategies to improve exposure in solid tumors. Cancer. 2007 Jan;109(2):170–179. doi:10.1002/cncr.22402.
-
(2007)
Cancer
, vol.109
, Issue.2
, pp. 170-179
-
-
Beckman, R.A.1
Weiner, L.M.2
Davis, H.M.3
-
78
-
-
0030014521
-
Single chain Ig/gamma gene-redirected human T lymphocytes produce cytokines, specifically lyse tumor cells, and recycle lytic capacity
-
July
-
M.Weijtens, R.Willemsen, D.Valerio, et al. Single chain Ig/gamma gene-redirected human T lymphocytes produce cytokines, specifically lyse tumor cells, and recycle lytic capacity. J Immunol. 1996 July 15;157(2):836–843.
-
(1996)
J Immunol
, vol.157
, Issue.2
, pp. 836-843
-
-
Weijtens, M.1
Willemsen, R.2
Valerio, D.3
-
79
-
-
84967145937
-
Making better chimeric antigen receptors for adoptive T-cell therapy
-
Apr
-
M.V.Maus, C.H.June. Making better chimeric antigen receptors for adoptive T-cell therapy. Clin Cancer Res. 2016 Apr 15;22(8):1875–1884.
-
(2016)
Clin Cancer Res
, vol.22
, Issue.8
, pp. 1875-1884
-
-
Maus, M.V.1
June, C.H.2
-
80
-
-
10844296758
-
Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells
-
Dec
-
K.S.Kahlon, C.Brown, L.J.Cooper, et al. Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells. Cancer Res. 2004 Dec 15;64(24):9160–9166.
-
(2004)
Cancer Res
, vol.64
, Issue.24
, pp. 9160-9166
-
-
Kahlon, K.S.1
Brown, C.2
Cooper, L.J.3
-
81
-
-
74549196076
-
HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors
-
Jan
-
N.Ahmed, V.S.Salsman, Y.Kew, et al. HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors. Clin Cancer Res. 2010 Jan 15;16(2):474–485.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.2
, pp. 474-485
-
-
Ahmed, N.1
Salsman, V.S.2
Kew, Y.3
-
82
-
-
84875215925
-
T cells redirected to EphA2 for the immunotherapy of glioblastoma
-
Mar
-
K.K.Chow, S.Naik, S.Kakarla, et al. T cells redirected to EphA2 for the immunotherapy of glioblastoma. Mol Ther. 2013 Mar;21(3):629–637. doi:10.1038/mt.2012.210.
-
(2013)
Mol Ther
, vol.21
, Issue.3
, pp. 629-637
-
-
Chow, K.K.1
Naik, S.2
Kakarla, S.3
-
83
-
-
84991035101
-
Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts
-
M.Ohno, T.Ohkuri, A.Kosaka, et al. Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts. J Immunother Cancer. 2013;1:21. doi:10.1186/2051-1426-1-21.
-
(2013)
J Immunother Cancer
, vol.1
, pp. 21
-
-
Ohno, M.1
Ohkuri, T.2
Kosaka, A.3
-
84
-
-
84923078274
-
Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma
-
Feb
-
L.A.Johnson, J.Scholler, T.Ohkuri, et al. Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma. Sci Transl Med. 2015 Feb 18;7(275):275ra22.
-
(2015)
Sci Transl Med
, vol.7
, Issue.275
, pp. 275ra22
-
-
Johnson, L.A.1
Scholler, J.2
Ohkuri, T.3
-
85
-
-
69249248185
-
Genetically engineered T cells to target EGFRvIII expressing glioblastoma
-
Sep
-
S.S.Bullain, A.Sahin, O.Szentirmai, et al. Genetically engineered T cells to target EGFRvIII expressing glioblastoma. J Neurooncol. 2009 Sep;94(3):373–382. doi:10.1007/s11060-009-9889-1.
-
(2009)
J Neurooncol
, vol.94
, Issue.3
, pp. 373-382
-
-
Bullain, S.S.1
Sahin, A.2
Szentirmai, O.3
-
86
-
-
77950475517
-
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
-
R.A.Morgan, J.C.Yang, M.Kitano, et al. Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther. 2010;18(4):843–851. doi:10.1038/mt.2010.24.
-
(2010)
Mol Ther
, vol.18
, Issue.4
, pp. 843-851
-
-
Morgan, R.A.1
Yang, J.C.2
Kitano, M.3
-
87
-
-
84942908170
-
Bioactivity and safety of IL13Ralpha2-redirected chimeric antigen receptor CD8+ T cells in patients with recurrent glioblastoma
-
Sep
-
C.E.Brown, B.Badie, M.E.Barish, et al. Bioactivity and safety of IL13Ralpha2-redirected chimeric antigen receptor CD8+ T cells in patients with recurrent glioblastoma. Clin Cancer Res. 2015 Sep 15;21(18):4062–4072.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.18
, pp. 4062-4072
-
-
Brown, C.E.1
Badie, B.2
Barish, M.E.3
-
88
-
-
55549145071
-
Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
-
Nov
-
M.A.Pule, B.Savoldo, G.D.Myers, et al. Virus-specific T cells engineered to coexpress tumor-specific receptors:persistence and antitumor activity in individuals with neuroblastoma. Nat Med. 2008 Nov;14(11):1264–1270. doi:10.1038/nm.1882.
-
(2008)
Nat Med
, vol.14
, Issue.11
, pp. 1264-1270
-
-
Pule, M.A.1
Savoldo, B.2
Myers, G.D.3
-
89
-
-
84887471195
-
Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma
-
Nov
-
M.Hegde, A.Corder, K.K.Chow, et al. Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma. Mol Ther. 2013 Nov;21(11):2087–2101. doi:10.1038/mt.2013.185.
-
(2013)
Mol Ther
, vol.21
, Issue.11
, pp. 2087-2101
-
-
Hegde, M.1
Corder, A.2
Chow, K.K.3
-
90
-
-
84872196489
-
Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
-
Jan
-
C.C.Kloss, M.Condomines, M.Cartellieri, et al. Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells. Nat Biotechnol. 2013 Jan;31(1):71–75. doi:10.1038/nbt.2459.
-
(2013)
Nat Biotechnol
, vol.31
, Issue.1
, pp. 71-75
-
-
Kloss, C.C.1
Condomines, M.2
Cartellieri, M.3
-
91
-
-
84866740895
-
Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling
-
Oct
-
S.Wilkie, M.C.Van Schalkwyk, S.Hobbs, et al. Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling. J Clin Immunol. 2012 Oct;32(5):1059–1070. doi:10.1007/s10875-012-9689-9.
-
(2012)
J Clin Immunol
, vol.32
, Issue.5
, pp. 1059-1070
-
-
Wilkie, S.1
Van Schalkwyk, M.C.2
Hobbs, S.3
-
92
-
-
84880259439
-
TanCAR: a novel bispecific chimeric antigen receptor for cancer immunotherapy
-
Z.Grada, M.Hegde, T.Byrd, et al. TanCAR:a novel bispecific chimeric antigen receptor for cancer immunotherapy. Mol Ther Nucleic Acids. 2013;2:e105. doi:10.1038/mtna.2013.32.
-
(2013)
Mol Ther Nucleic Acids
, vol.2
, pp. e105
-
-
Grada, Z.1
Hegde, M.2
Byrd, T.3
-
93
-
-
84930199712
-
Seatbelts in CAR therapy: how safe are CARS?
-
K.Minagawa, X.Zhou, S.Mineishi, et al. Seatbelts in CAR therapy:how safe are CARS? Pharmaceuticals (Basel). 2015;8(2):230–249. doi:10.3390/ph8020230.
-
(2015)
Pharmaceuticals (Basel)
, vol.8
, Issue.2
, pp. 230-249
-
-
Minagawa, K.1
Zhou, X.2
Mineishi, S.3
-
94
-
-
84958214384
-
Precision tumor recognition by T cells with combinatorial antigen-sensing circuits
-
Feb
-
K.T.Roybal, L.J.Rupp, L.Morsut, et al. Precision tumor recognition by T cells with combinatorial antigen-sensing circuits. Cell. 2016 Feb 11;164(4):770–779.
-
(2016)
Cell
, vol.164
, Issue.4
, pp. 770-779
-
-
Roybal, K.T.1
Rupp, L.J.2
Morsut, L.3
-
95
-
-
84906557615
-
A vaccine targeting mutant IDH1 induces antitumour immunity
-
Jun
-
T.Schumacher, L.Bunse, S.Pusch, et al. A vaccine targeting mutant IDH1 induces antitumour immunity. Nature. 2014 Jun 25;512:324–327. doi:10.1038/nature13387.
-
(2014)
Nature
, vol.512
, pp. 324-327
-
-
Schumacher, T.1
Bunse, L.2
Pusch, S.3
-
96
-
-
84883866836
-
Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells
-
Aug
-
B.J.Cameron, A.B.Gerry, J.Dukes, et al. Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells. Sci Transl Med. 2013 Aug 7;5(197):197ra03.
-
(2013)
Sci Transl Med
, vol.5
, Issue.197
, pp. 197ra03
-
-
Cameron, B.J.1
Gerry, A.B.2
Dukes, J.3
-
97
-
-
78149254368
-
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
-
Nov
-
J.H.Sampson, A.B.Heimberger, G.E.Archer, et al. Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. J Clin Oncol. 2010 Nov 1;28(31):4722–4729.
-
(2010)
J Clin Oncol
, vol.28
, Issue.31
, pp. 4722-4729
-
-
Sampson, J.H.1
Heimberger, A.B.2
Archer, G.E.3
-
98
-
-
84866941861
-
Myeloid-derived suppressor cells in gliomas and glioma-development
-
G.Kohanbash, H.Okada. Myeloid-derived suppressor cells in gliomas and glioma-development. Immunol Invest. 2012;41(6–7):658–679. doi:10.3109/08820139.2012.689591.
-
(2012)
Immunol Invest
, vol.41
, Issue.6-7
, pp. 658-679
-
-
Kohanbash, G.1
Okada, H.2
-
99
-
-
84920969943
-
Induction of robust type-I CD8+ T-cell responses in WHO grade 2 low-grade glioma patients receiving peptide-based vaccines in combination with Poly-ICLC
-
Jan
-
H.Okada, L.H.Butterfield, R.L.Hamilton, et al. Induction of robust type-I CD8+ T-cell responses in WHO grade 2 low-grade glioma patients receiving peptide-based vaccines in combination with Poly-ICLC. Clin Cancer Res. 2015 Jan 15;21(2):286–294.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.2
, pp. 286-294
-
-
Okada, H.1
Butterfield, L.H.2
Hamilton, R.L.3
-
100
-
-
4143114769
-
Delivery of interferon-alpha transfected dendritic cells into central nervous system tumors enhances the antitumor efficacy of peripheral peptide-based vaccines
-
H.Okada, T.Tsugawa, H.Sato, et al. Delivery of interferon-alpha transfected dendritic cells into central nervous system tumors enhances the antitumor efficacy of peripheral peptide-based vaccines. Cancer Res. 2004;64(16):5830–5838. doi:10.1158/0008-5472.CAN-04-0130.
-
(2004)
Cancer Res
, vol.64
, Issue.16
, pp. 5830-5838
-
-
Okada, H.1
Tsugawa, T.2
Sato, H.3
-
101
-
-
84905817445
-
Antigen-specific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and nonbrainstem gliomas
-
Jul
-
I.F.Pollack, R.I.Jakacki, L.H.Butterfield, et al. Antigen-specific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and nonbrainstem gliomas. J Clin Oncol. 2014 Jul 1;32(19):2050–2058.
-
(2014)
J Clin Oncol
, vol.32
, Issue.19
, pp. 2050-2058
-
-
Pollack, I.F.1
Jakacki, R.I.2
Butterfield, L.H.3
-
102
-
-
0036428790
-
Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2
-
Nov
-
M.H.Kershaw, G.Wang, J.A.Westwood, et al. Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2. Hum Gene Ther. 2002 Nov 1;13(16):1971–1980.
-
(2002)
Hum Gene Ther
, vol.13
, Issue.16
, pp. 1971-1980
-
-
Kershaw, M.H.1
Wang, G.2
Westwood, J.A.3
-
103
-
-
67650638846
-
T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model
-
Jun
-
A.Di Stasi, B.De Angelis, C.M.Rooney, et al. T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model. Blood. 2009 Jun 18;113(25):6392–6402.
-
(2009)
Blood
, vol.113
, Issue.25
, pp. 6392-6402
-
-
Di Stasi, A.1
De Angelis, B.2
Rooney, C.M.3
-
104
-
-
77958063691
-
Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b
-
Oct
-
J.A.Craddock, A.Lu, A.Bear, et al. Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b. J Immunother. 2010 Oct;33(8):780–788. doi:10.1097/CJI.0b013e3181ee6675.
-
(2010)
J Immunother
, vol.33
, Issue.8
, pp. 780-788
-
-
Craddock, J.A.1
Lu, A.2
Bear, A.3
-
105
-
-
79960403269
-
Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor
-
Jul
-
E.K.Moon, C.Carpenito, J.Sun, et al. Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor. Clin Cancer Res. 2011 Jul 15;17(14):4719–4730.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.14
, pp. 4719-4730
-
-
Moon, E.K.1
Carpenito, C.2
Sun, J.3
-
106
-
-
80051693219
-
Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide
-
Aug
-
S.A.Grossman, X.Ye, G.Lesser, et al. Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide. Clin Cancer Res. 2011 Aug 15;17(16):5473–5480.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.16
, pp. 5473-5480
-
-
Grossman, S.A.1
Ye, X.2
Lesser, G.3
-
107
-
-
84936934796
-
TRUCKs: the fourth generation of CARs
-
M.Chmielewski, H.Abken. TRUCKs:the fourth generation of CARs. Expert Opin Biol Ther. 2015;15(8):1145–1154. doi:10.1517/14712598.2015.1046430.
-
(2015)
Expert Opin Biol Ther
, vol.15
, Issue.8
, pp. 1145-1154
-
-
Chmielewski, M.1
Abken, H.2
-
108
-
-
77956280888
-
Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts
-
Sep
-
S.P.Kerkar, P.Muranski, A.Kaiser, et al. Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts. Cancer Res. 2010 Sep 1;70(17):6725–6734.
-
(2010)
Cancer Res
, vol.70
, Issue.17
, pp. 6725-6734
-
-
Kerkar, S.P.1
Muranski, P.2
Kaiser, A.3
-
109
-
-
79953325686
-
Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment
-
Apr
-
L.Zhang, S.P.Kerkar, Z.Yu, et al. Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment. Mol Ther. 2011 Apr;19(4):751–759. doi:10.1038/mt.2010.313.
-
(2011)
Mol Ther
, vol.19
, Issue.4
, pp. 751-759
-
-
Zhang, L.1
Kerkar, S.P.2
Yu, Z.3
-
110
-
-
80052257433
-
IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression
-
Sep
-
M.Chmielewski, C.Kopecky, A.A.Hombach, et al. IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression. Cancer Res. 2011 Sep 1;71(17):5697–5706.
-
(2011)
Cancer Res
, vol.71
, Issue.17
, pp. 5697-5706
-
-
Chmielewski, M.1
Kopecky, C.2
Hombach, A.A.3
-
111
-
-
0036566184
-
Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity
-
May
-
C.M.Bollard, C.Rossig, M.J.Calonge, et al. Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity. Blood. 2002 May 1;99(9):3179–3187.
-
(2002)
Blood
, vol.99
, Issue.9
, pp. 3179-3187
-
-
Bollard, C.M.1
Rossig, C.2
Calonge, M.J.3
-
112
-
-
84886856247
-
Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytes
-
Aug
-
D.Abate-Daga, K.Hanada, J.L.Davis, et al. Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytes. Blood. 2013 Aug 22;122(8):1399–1410.
-
(2013)
Blood
, vol.122
, Issue.8
, pp. 1399-1410
-
-
Abate-Daga, D.1
Hanada, K.2
Davis, J.L.3
-
113
-
-
84886397930
-
Anti-PD-1 antibody therapy potently enhances the eradication of established tumors by gene-modified T cells
-
Oct
-
L.B.John, C.Devaud, C.P.Duong, et al. Anti-PD-1 antibody therapy potently enhances the eradication of established tumors by gene-modified T cells. Clin Cancer Res. 2013 Oct 15;19(20):5636–5646.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.20
, pp. 5636-5646
-
-
John, L.B.1
Devaud, C.2
Duong, C.P.3
-
114
-
-
84904609350
-
Blockade of PD-1 immunosuppression boosts CAR T-cell therapy
-
Oct
-
L.B.John, M.H.Kershaw, P.K.Darcy. Blockade of PD-1 immunosuppression boosts CAR T-cell therapy. Oncoimmunology. 2013 Oct 1;2(10):e26286.
-
(2013)
Oncoimmunology
, vol.2
, Issue.10
, pp. e26286
-
-
John, L.B.1
Kershaw, M.H.2
Darcy, P.K.3
-
115
-
-
79955667525
-
Do we need novel radiologic response criteria for brain tumor immunotherapy?
-
H.Okada, I.F.Pollack. Do we need novel radiologic response criteria for brain tumor immunotherapy? Expert Rev Neurother. 2011;11(5):619–622. doi:10.1586/ern.11.49.
-
(2011)
Expert Rev Neurother
, vol.11
, Issue.5
, pp. 619-622
-
-
Okada, H.1
Pollack, I.F.2
-
116
-
-
84960956996
-
Immunotherapy Response Assessment in Neuro-Oncology (iRANO): a report of the RANO working group
-
H.Okada, M.Weller, R.Huang, et al. immunotherapy Response Assessment in Neuro-Oncology (iRANO):a report of the RANO working group. Lancet Oncol. 2015;15:534–542. doi:10.1016/S1470-2045(15)00088-1.• This proposes a novel response criteria specifically designed for immunotherapy of brain tumors.
-
(2015)
Lancet Oncol
, vol.15
, pp. 534-542
-
-
Okada, H.1
Weller, M.2
Huang, R.3
-
117
-
-
73149092567
-
Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria
-
Dec
-
J.D.Wolchok, A.Hoos, S.O’Day, et al. Guidelines for the evaluation of immune therapy activity in solid tumors:immune-related response criteria. Clin Cancer Res. 2009 Dec 1;15(23):7412–7420.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.23
, pp. 7412-7420
-
-
Wolchok, J.D.1
Hoos, A.2
O’Day, S.3
-
118
-
-
77951625266
-
Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group
-
April
-
P.Y.Wen, D.R.Macdonald, D.A.Reardon, et al. Updated response assessment criteria for high-grade gliomas:response assessment in neuro-oncology working group. J Clin Oncol. 2010 April 10;28(11):1963–1972.
-
(2010)
J Clin Oncol
, vol.28
, Issue.11
, pp. 1963-1972
-
-
Wen, P.Y.1
Macdonald, D.R.2
Reardon, D.A.3
|