Dysregulated lysine acetyltransferase 2B promotes inflammatory bowel disease pathogenesis through transcriptional repression of interleukin-10

Journal of Crohn's and Colitis

Volumn 10, Issue 6, 2016, Pages 726-734

  Bai, Alfa H C ^a   Wu, William K K ^a,b   Xu, Liangliang ^b   Wong, Sunny H ^a   Go, Minnie Y ^a   Chan, Anthony W H ^b   Harbord, Marcus ^c   Zhang, Shenghong ^d   Chen, Minhu ^d   Wu, Justin C Y ^a   Chan, Michael W Y ^e   Chan, Matthew T V ^b   Chan, Francis K L ^a   Sung, Joseph J Y ^a   Yu, Jun ^a   Cheng, Alfred S L ^a,b   Ng, Siew Chien ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^c CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

^d SUN YAT SEN UNIVERSITY   (China)

^e NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

Author keywords

Epigenetics; Histone acetylation; IL 10; KAT2B

Indexed keywords

ACYLTRANSFERASE; ANACARDIC ACID; HISTONE H4; HISTONE H4 LYSINE 5; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 23P19; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; LUCIFERASE; LYSINE; LYSINE ACETYLTRANSFERASE 2B; MESSENGER RNA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; HISTONE ACETYLTRANSFERASE PCAF; IL10 PROTEIN, HUMAN; KAT2B PROTEIN, HUMAN; P300-CBP-ASSOCIATED FACTOR;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; COLON MUCOSA; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROHN DISEASE; DOWN REGULATION; ENZYME ACTIVITY; EPIGENETIC REPRESSION; GENE EXPRESSION; GENE EXPRESSION PROFILING; HISTONE ACETYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINAL TISSUE; INTESTINE EPITHELIUM CELL; MOLECULAR PATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ULCERATIVE COLITIS; WESTERN BLOTTING; CASE CONTROL STUDY; CELL LINE; COLON; DNA MICROARRAY; GENETIC EPIGENESIS; GENETICS; HISTONE CODE; IMMUNOLOGY; INFLAMMATORY BOWEL DISEASE; METABOLISM;

BIOMARKERS; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CELL LINE; COLON; DOWN-REGULATION; EPIGENESIS, GENETIC; GENE EXPRESSION PROFILING; HISTONE CODE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-10; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; P300-CBP TRANSCRIPTION FACTORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84984972931     PISSN: 18739946     EISSN: 18764479     Source Type: Journal    
DOI: 10.1093/ecco-jcc/jjw020     Document Type: Article

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