메뉴 건너뛰기




Volumn 4, Issue 4, 2015, Pages 596-607

Current trends in the etiology and diagnosis of HPV-related head and neck cancers

Author keywords

HPV; Biomarkers; Epidemiology; Oropharyngeal cancer; Saliva diagnostics

Indexed keywords

IMMUNOGLOBULIN G; ONCOPROTEIN; PROTEIN E6; PROTEIN E7; VIRUS DNA; VIRUS RNA; WART VIRUS VACCINE; CYCLIN DEPENDENT KINASE INHIBITOR 2A;

EID: 84984905668     PISSN: None     EISSN: 20457634     Source Type: Journal    
DOI: 10.1002/cam4.424     Document Type: Review
Times cited : (101)

References (100)
  • 4
    • 34648825016 scopus 로고    scopus 로고
    • Trends in head and neck cancer incidence in relation to smoking prevalence
    • Sturgis, E. M., and P. M. Cinciripini 2007. Trends in head and neck cancer incidence in relation to smoking prevalence. Cancer 110:1429-1435.
    • (2007) Cancer , vol.110 , pp. 1429-1435
    • Sturgis, E.M.1    Cinciripini, P.M.2
  • 5
    • 34447266437 scopus 로고    scopus 로고
    • Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium
    • Hashibe, M., P. Brennan, S. Benhamou, X. Castellsague, C. Chen, M. P. Curado, et al. 2007. Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. J. Natl. Cancer Inst. 99:777-789.
    • (2007) J. Natl. Cancer Inst. , vol.99 , pp. 777-789
    • Hashibe, M.1    Brennan, P.2    Benhamou, S.3    Castellsague, X.4    Chen, C.5    Curado, M.P.6
  • 6
    • 33847651765 scopus 로고    scopus 로고
    • Cancer risk associated with alcohol and tobacco use: focus on upper aero-digestive tract and liver
    • Pelucchi, C., S. Gallus, W. Garavello, C. Bosetti, and C. La Vecchia 2006. Cancer risk associated with alcohol and tobacco use: focus on upper aero-digestive tract and liver. Alcohol Res. Health 29:193-198.
    • (2006) Alcohol Res. Health , vol.29 , pp. 193-198
    • Pelucchi, C.1    Gallus, S.2    Garavello, W.3    Bosetti, C.4    La Vecchia, C.5
  • 7
    • 77955282693 scopus 로고    scopus 로고
    • HPV-associated head and neck cancer: a virus-related cancer epidemic
    • Marur, S., G. D'Souza, W. H. Westra, and A. A. Forastiere 2010. HPV-associated head and neck cancer: a virus-related cancer epidemic. Lancet Oncol. 11:781-789.
    • (2010) Lancet Oncol. , vol.11 , pp. 781-789
    • Marur, S.1    D'Souza, G.2    Westra, W.H.3    Forastiere, A.A.4
  • 8
    • 84898775735 scopus 로고    scopus 로고
    • Role of human papillomavirus in non-oropharyngeal head and neck cancers
    • Combes, J.-D., and S. Franceschi 2014. Role of human papillomavirus in non-oropharyngeal head and neck cancers. Oral Oncol. 50:370-379.
    • (2014) Oral Oncol. , vol.50 , pp. 370-379
    • Combes, J.-D.1    Franceschi, S.2
  • 9
    • 0141523103 scopus 로고    scopus 로고
    • Comparative genomic hybridization analysis of tonsillar cancer reveals a different pattern of genomic imbalances in human papillomavirus-positive and-negative tumors
    • Dahlgren, L., H. Mellin, D. Wangsa, K. Heselmeyer-Haddad, L. Björnestål, J. Lindholm, et al. 2003. Comparative genomic hybridization analysis of tonsillar cancer reveals a different pattern of genomic imbalances in human papillomavirus-positive and-negative tumors. Int. J. Cancer 107:244-249.
    • (2003) Int. J. Cancer , vol.107 , pp. 244-249
    • Dahlgren, L.1    Mellin, H.2    Wangsa, D.3    Heselmeyer-Haddad, K.4    Björnestål, L.5    Lindholm, J.6
  • 10
    • 84900489886 scopus 로고    scopus 로고
    • The clinical impact of HPV tumor status upon head and neck squamous cell carcinomas
    • Benson, E., R. Li, D. Eisele, and C. Fakhry 2013. The clinical impact of HPV tumor status upon head and neck squamous cell carcinomas. Oral Oncol. 50:565-574.
    • (2013) Oral Oncol. , vol.50 , pp. 565-574
    • Benson, E.1    Li, R.2    Eisele, D.3    Fakhry, C.4
  • 11
  • 12
    • 41449085148 scopus 로고    scopus 로고
    • Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers
    • Gillison, M. L., G. D'Souza, W. Westra, E. Sugar, W. Xiao, S. Begum, et al. 2008. Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers. J. Natl. Cancer Inst. 100:407-420.
    • (2008) J. Natl. Cancer Inst. , vol.100 , pp. 407-420
    • Gillison, M.L.1    D'Souza, G.2    Westra, W.3    Sugar, E.4    Xiao, W.5    Begum, S.6
  • 13
    • 84898646054 scopus 로고    scopus 로고
    • Prevalence and risk factors for oral HPV infection in young Australians
    • Antonsson, A., M. Cornford, S. Perry, M. Davis, M. Dunne, and D. Whiteman 2013. Prevalence and risk factors for oral HPV infection in young Australians. PLoS One 9:e91761.
    • (2013) PLoS One , vol.9 , pp. e91761
    • Antonsson, A.1    Cornford, M.2    Perry, S.3    Davis, M.4    Dunne, M.5    Whiteman, D.6
  • 15
    • 84857065859 scopus 로고    scopus 로고
    • Prevalence of oral HPV infection in the United States, 2009-2010
    • Gillison, M. L., T. Broutian, R. K. Pickard, Z.-Y. Tong, W. Xiao, L. Kahle, et al. 2012. Prevalence of oral HPV infection in the United States, 2009-2010. JAMA 307:693-703.
    • (2012) JAMA , vol.307 , pp. 693-703
    • Gillison, M.L.1    Broutian, T.2    Pickard, R.K.3    Tong, Z.-Y.4    Xiao, W.5    Kahle, L.6
  • 17
    • 34249093548 scopus 로고    scopus 로고
    • A 2-year prospective study of human papillomavirus persistence among women with a cytological diagnosis of atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion
    • Plummer, M., M. Schiffman, P. E. Castle, D. Maucort-Boulch, and C. M. Wheeler 2007. A 2-year prospective study of human papillomavirus persistence among women with a cytological diagnosis of atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion. J. Infect. Dis. 195:1582-1589.
    • (2007) J. Infect. Dis. , vol.195 , pp. 1582-1589
    • Plummer, M.1    Schiffman, M.2    Castle, P.E.3    Maucort-Boulch, D.4    Wheeler, C.M.5
  • 18
    • 0037077876 scopus 로고    scopus 로고
    • Type specific persistence of high risk human papillomavirus (HPV) as indicator of high grade cervical squamous intraepithelial lesions in young women: population based prospective follow up study
    • Kjaer, S. K., A. J. C. van den Brule, G. Paull, E. I. Svare, M. E. Sherman, B. L. Thomsen, et al. 2002. Type specific persistence of high risk human papillomavirus (HPV) as indicator of high grade cervical squamous intraepithelial lesions in young women: population based prospective follow up study. BMJ 325:572.
    • (2002) BMJ , vol.325 , pp. 572
    • Kjaer, S.K.1    van den Brule, A.J.C.2    Paull, G.3    Svare, E.I.4    Sherman, M.E.5    Thomsen, B.L.6
  • 19
    • 84861648384 scopus 로고    scopus 로고
    • Global burden of cancers attributable to infections in 2008: a review and synthetic analysis
    • De Martel, C., J. Ferlay, S. Franceschi, J. Vignat, F. Bray, D. Forman, et al. 2012. Global burden of cancers attributable to infections in 2008: a review and synthetic analysis. Lancet Oncol. 13:607-615.
    • (2012) Lancet Oncol. , vol.13 , pp. 607-615
    • De Martel, C.1    Ferlay, J.2    Franceschi, S.3    Vignat, J.4    Bray, F.5    Forman, D.6
  • 20
    • 79956300394 scopus 로고    scopus 로고
    • Trends in head and neck cancer incidence in Denmark, 1978-2007: focus on human papillomavirus associated sites
    • Blomberg, M., A. Nielsen, C. Munk, and S. K. Kjaer 2011. Trends in head and neck cancer incidence in Denmark, 1978-2007: focus on human papillomavirus associated sites. Int. J. Cancer 129:733-741.
    • (2011) Int. J. Cancer , vol.129 , pp. 733-741
    • Blomberg, M.1    Nielsen, A.2    Munk, C.3    Kjaer, S.K.4
  • 21
    • 77950596891 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the oropharynx in Australian males induced by human papillomavirus vaccine targets
    • Hong, A. M., A. E. Grulich, D. Jones, C. S. Lee, S. M. Garland, T. A. Dobbins, et al. 2010. Squamous cell carcinoma of the oropharynx in Australian males induced by human papillomavirus vaccine targets. Vaccine 28:3269-3272.
    • (2010) Vaccine , vol.28 , pp. 3269-3272
    • Hong, A.M.1    Grulich, A.E.2    Jones, D.3    Lee, C.S.4    Garland, S.M.5    Dobbins, T.A.6
  • 22
    • 84887995124 scopus 로고    scopus 로고
    • Eurogin Roadmap: comparative epidemiology of HPV infection and associated cancers of the head and neck and cervix
    • Gillison, M. L., X. Castellsagué, A. Chaturvedi, M. T. Goodman, P. Snijders, M. Tommasino, et al. 2014. Eurogin Roadmap: comparative epidemiology of HPV infection and associated cancers of the head and neck and cervix. Int. J. Cancer 134:497-507.
    • (2014) Int. J. Cancer , vol.134 , pp. 497-507
    • Gillison, M.L.1    Castellsagué, X.2    Chaturvedi, A.3    Goodman, M.T.4    Snijders, P.5    Tommasino, M.6
  • 23
    • 0347915672 scopus 로고    scopus 로고
    • Age, sexual behavior and human papillomavirus infection in oral cavity and oropharyngeal cancers
    • Smith, E. M., J. M. Ritchie, K. F. Summersgill, J. P. Klussmann, J. H. Lee, D. Wang, et al. 2004. Age, sexual behavior and human papillomavirus infection in oral cavity and oropharyngeal cancers. Int. J. Cancer 108:766-772.
    • (2004) Int. J. Cancer , vol.108 , pp. 766-772
    • Smith, E.M.1    Ritchie, J.M.2    Summersgill, K.F.3    Klussmann, J.P.4    Lee, J.H.5    Wang, D.6
  • 24
    • 84876116144 scopus 로고    scopus 로고
    • Human papillomavirus, smoking status and outcomes in tonsillar squamous cell carcinoma
    • Hong, A. M., A. Martin, M. Chatfield, D. Jones, M. Zhang, B. Armstrong, et al. 2013. Human papillomavirus, smoking status and outcomes in tonsillar squamous cell carcinoma. Int. J. Cancer 132:2748-2754.
    • (2013) Int. J. Cancer , vol.132 , pp. 2748-2754
    • Hong, A.M.1    Martin, A.2    Chatfield, M.3    Jones, D.4    Zhang, M.5    Armstrong, B.6
  • 25
    • 77952312776 scopus 로고    scopus 로고
    • Sexual behaviours and the risk of head and neck cancers: a pooled analysis in the International Head and Neck Cancer Epidemiology (INHANCE) consortium
    • Heck, J. E., J. Berthiller, S. Vaccarella, D. M. Winn, E. M. Smith, O. Shan'gina, et al. 2010. Sexual behaviours and the risk of head and neck cancers: a pooled analysis in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. Int. J. Epidemiol. 39:166-181.
    • (2010) Int. J. Epidemiol. , vol.39 , pp. 166-181
    • Heck, J.E.1    Berthiller, J.2    Vaccarella, S.3    Winn, D.M.4    Smith, E.M.5    Shan'gina, O.6
  • 26
    • 79955913112 scopus 로고    scopus 로고
    • Differences in history of sexual behavior between patients with oropharyngeal squamous cell carcinoma and patients with squamous cell carcinoma at other head and neck sites
    • Dahlstrom, K. R., G. Li, G. Tortolero-Luna, Q. Wei, and E. M. Sturgis 2011. Differences in history of sexual behavior between patients with oropharyngeal squamous cell carcinoma and patients with squamous cell carcinoma at other head and neck sites. Head Neck 33:847-855.
    • (2011) Head Neck , vol.33 , pp. 847-855
    • Dahlstrom, K.R.1    Li, G.2    Tortolero-Luna, G.3    Wei, Q.4    Sturgis, E.M.5
  • 27
    • 0346258152 scopus 로고    scopus 로고
    • Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study
    • Herrero, R., X. Castellsagué, M. Pawlita, J. Lissowska, F. Kee, P. Balaram, et al. 2003. Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study. J. Natl. Cancer Inst. 95:1772-1783.
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 1772-1783
    • Herrero, R.1    Castellsagué, X.2    Pawlita, M.3    Lissowska, J.4    Kee, F.5    Balaram, P.6
  • 29
    • 33644849030 scopus 로고    scopus 로고
    • Molecular classification identifies a subset of human papillomavirus-associated oropharyngeal cancers with favorable prognosis
    • Weinberger, P. M., Z. Yu, B. G. Haffty, D. Kowalski, M. Harigopal, J. Brandsma, et al. 2006. Molecular classification identifies a subset of human papillomavirus-associated oropharyngeal cancers with favorable prognosis. J. Clin. Oncol. 24:736-747.
    • (2006) J. Clin. Oncol. , vol.24 , pp. 736-747
    • Weinberger, P.M.1    Yu, Z.2    Haffty, B.G.3    Kowalski, D.4    Harigopal, M.5    Brandsma, J.6
  • 30
    • 39649109915 scopus 로고    scopus 로고
    • Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial
    • Fakhry, C., W. H. Westra, S. Li, A. Cmelak, J. A. Ridge, H. Pinto, et al. 2008. Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J. Natl. Cancer Inst. 100:261-269.
    • (2008) J. Natl. Cancer Inst. , vol.100 , pp. 261-269
    • Fakhry, C.1    Westra, W.H.2    Li, S.3    Cmelak, A.4    Ridge, J.A.5    Pinto, H.6
  • 31
    • 0027050013 scopus 로고
    • Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic
    • Kirnbauer, R., F. Booy, N. Cheng, D. Lowy, and J. Schiller 1992. Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic. Proc. Natl. Acad. Sci. 89:12180-12184.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 12180-12184
    • Kirnbauer, R.1    Booy, F.2    Cheng, N.3    Lowy, D.4    Schiller, J.5
  • 32
    • 84855300842 scopus 로고    scopus 로고
    • Overall efficacy of HPV-16/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasia: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial
    • Lehtinen, M., J. Paavonen, C. M. Wheeler, U. Jaisamrarn, S. M. Garland, X. Castellsagué, et al. 2012. Overall efficacy of HPV-16/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasia: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial. Lancet Oncol. 13:89-99.
    • (2012) Lancet Oncol. , vol.13 , pp. 89-99
    • Lehtinen, M.1    Paavonen, J.2    Wheeler, C.M.3    Jaisamrarn, U.4    Garland, S.M.5    Castellsagué, X.6
  • 33
    • 77749279739 scopus 로고    scopus 로고
    • Impact of human papillomavirus (HPV)-6/11/16/18 vaccine on all HPV-associated genital diseases in young women
    • Muñoz, N., S. K. Kjaer, K. Sigurdsson, O.-E. Iversen, M. Hernandez-Avila, C. M. Wheeler, et al. 2010. Impact of human papillomavirus (HPV)-6/11/16/18 vaccine on all HPV-associated genital diseases in young women. J. Natl. Cancer Inst. 102:325-339.
    • (2010) J. Natl. Cancer Inst. , vol.102 , pp. 325-339
    • Muñoz, N.1    Kjaer, S.K.2    Sigurdsson, K.3    Iversen, O.-E.4    Hernandez-Avila, M.5    Wheeler, C.M.6
  • 36
    • 84880428460 scopus 로고    scopus 로고
    • Reduced prevalence of oral human papillomavirus (HPV) 4 years after bivalent HPV vaccination in a randomized clinical trial in Costa Rica
    • Herrero, R., W. Quint, A. Hildesheim, P. Gonzalez, L. Struijk, H. A. Katki, et al. 2013. Reduced prevalence of oral human papillomavirus (HPV) 4 years after bivalent HPV vaccination in a randomized clinical trial in Costa Rica. PLoS One 8:e68329.
    • (2013) PLoS One , vol.8 , pp. e68329
    • Herrero, R.1    Quint, W.2    Hildesheim, A.3    Gonzalez, P.4    Struijk, L.5    Katki, H.A.6
  • 38
    • 55749086974 scopus 로고    scopus 로고
    • Human papillomavirus in HNSCC: recognition of a distinct disease type
    • Vidal, L., and M. L. Gillison 2008. Human papillomavirus in HNSCC: recognition of a distinct disease type. Hematol. Oncol. Clin. North Am. 22:1125-1142.
    • (2008) Hematol. Oncol. Clin. North Am. , vol.22 , pp. 1125-1142
    • Vidal, L.1    Gillison, M.L.2
  • 40
    • 33748761925 scopus 로고    scopus 로고
    • The burden of HPV-related cancers
    • Parkin, D. M., and F. Bray 2006. The burden of HPV-related cancers. Vaccine 24:S11-S25.
    • (2006) Vaccine , vol.24 , pp. S11-S25
    • Parkin, D.M.1    Bray, F.2
  • 41
    • 33750920705 scopus 로고    scopus 로고
    • Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis
    • DeGregori, J., and D. G. Johnson 2006. Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis. Curr. Mol. Med. 6:739-748.
    • (2006) Curr. Mol. Med. , vol.6 , pp. 739-748
    • DeGregori, J.1    Johnson, D.G.2
  • 42
    • 0026568793 scopus 로고
    • Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product
    • Chellappan, S., V. B. Kraus, B. Kroger, K. Munger, P. M. Howley, W. Phelps, et al. 1992. Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc. Natl. Acad. Sci. 89:4549-4553.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 4549-4553
    • Chellappan, S.1    Kraus, V.B.2    Kroger, B.3    Munger, K.4    Howley, P.M.5    Phelps, W.6
  • 43
    • 0029134617 scopus 로고
    • Sequential activation of cyclin E and cyclin A gene expression by human papillomavirus type 16 E7 through sequences necessary for transformation
    • Zerfass, K., A. Schulze, D. Spitkovsky, V. Friedman, B. Henglein, and P. Jansen-Dürr 1995. Sequential activation of cyclin E and cyclin A gene expression by human papillomavirus type 16 E7 through sequences necessary for transformation. J. Virol. 69:6389-6399.
    • (1995) J. Virol. , vol.69 , pp. 6389-6399
    • Zerfass, K.1    Schulze, A.2    Spitkovsky, D.3    Friedman, V.4    Henglein, B.5    Jansen-Dürr, P.6
  • 44
    • 84885076128 scopus 로고    scopus 로고
    • Tumor suppressor p16INK4A is necessary for survival of cervical carcinoma cell lines
    • McLaughlin-Drubin, M. E., D. Park, and K. Munger 2013. Tumor suppressor p16INK4A is necessary for survival of cervical carcinoma cell lines. Proc. Natl. Acad. Sci. 110:16175-16180.
    • (2013) Proc. Natl. Acad. Sci. , vol.110 , pp. 16175-16180
    • McLaughlin-Drubin, M.E.1    Park, D.2    Munger, K.3
  • 45
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner, M., B. A. Werness, J. M. Huibregtse, A. J. Levine, and P. M. Howley 1990. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63:1129-1136.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 46
    • 65349107653 scopus 로고    scopus 로고
    • E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells
    • Rampias, T., C. Sasaki, P. Weinberger, and A. Psyrri 2009. E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells. J. Natl. Cancer Inst. 101:412-423.
    • (2009) J. Natl. Cancer Inst. , vol.101 , pp. 412-423
    • Rampias, T.1    Sasaki, C.2    Weinberger, P.3    Psyrri, A.4
  • 47
    • 0037077205 scopus 로고    scopus 로고
    • The human papillomavirus 16 E6 protein binds to tumor necrosis factor (TNF) R1 and protects cells from TNF-induced apoptosis
    • Filippova, M., H. Song, J. L. Connolly, T. S. Dermody, and P. J. Duerksen-Hughes 2002. The human papillomavirus 16 E6 protein binds to tumor necrosis factor (TNF) R1 and protects cells from TNF-induced apoptosis. J. Biol. Chem. 277:21730-21739.
    • (2002) J. Biol. Chem. , vol.277 , pp. 21730-21739
    • Filippova, M.1    Song, H.2    Connolly, J.L.3    Dermody, T.S.4    Duerksen-Hughes, P.J.5
  • 48
    • 33751398479 scopus 로고    scopus 로고
    • Modulation of apoptosis by human papillomavirus (HPV) oncoproteins
    • Garnett, T., and P. Duerksen-Hughes 2006. Modulation of apoptosis by human papillomavirus (HPV) oncoproteins. Arch. Virol. 151:2321-2335.
    • (2006) Arch. Virol. , vol.151 , pp. 2321-2335
    • Garnett, T.1    Duerksen-Hughes, P.2
  • 49
    • 0028331229 scopus 로고
    • Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins
    • White, A. E., E. M. Livanos, and T. D. Tlsty 1994. Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins. Genes Dev. 8:666-677.
    • (1994) Genes Dev. , vol.8 , pp. 666-677
    • White, A.E.1    Livanos, E.M.2    Tlsty, T.D.3
  • 50
    • 70349905411 scopus 로고    scopus 로고
    • Centrosome overduplication, chromosomal instability, and human papillomavirus oncoproteins
    • Duensing, A., N. Spardy, P. Chatterjee, L. Zheng, J. Parry, R. Cuevas, et al. 2009. Centrosome overduplication, chromosomal instability, and human papillomavirus oncoproteins. Environ. Mol. Mutagen. 50:741-747.
    • (2009) Environ. Mol. Mutagen. , vol.50 , pp. 741-747
    • Duensing, A.1    Spardy, N.2    Chatterjee, P.3    Zheng, L.4    Parry, J.5    Cuevas, R.6
  • 51
    • 1242338787 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 and E7 cause polyploidy in human keratinocytes and up-regulation of G2-M-phase proteins
    • Patel, D., A. Incassati, N. Wang, and D. J. McCance 2004. Human papillomavirus type 16 E6 and E7 cause polyploidy in human keratinocytes and up-regulation of G2-M-phase proteins. Cancer Res. 64:1299-1306.
    • (2004) Cancer Res. , vol.64 , pp. 1299-1306
    • Patel, D.1    Incassati, A.2    Wang, N.3    McCance, D.J.4
  • 52
    • 0037114361 scopus 로고    scopus 로고
    • The role of human papillomavirus oncoproteins E6 and E7 in apoptosis
    • Finzer, P., A. Aguilar-Lemarroy, and F. Rösl 2002. The role of human papillomavirus oncoproteins E6 and E7 in apoptosis. Cancer Lett. 188:15-24.
    • (2002) Cancer Lett. , vol.188 , pp. 15-24
    • Finzer, P.1    Aguilar-Lemarroy, A.2    Rösl, F.3
  • 53
    • 0036897282 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability
    • Duensing, S., and K. Münger 2002. The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Res. 62:7075-7082.
    • (2002) Cancer Res. , vol.62 , pp. 7075-7082
    • Duensing, S.1    Münger, K.2
  • 54
    • 0029809740 scopus 로고    scopus 로고
    • Expression of HPV16 E6 or E7 increases integration of foreign DNA
    • Kessis, T. D., D. C. Connolly, L. Hedrick, and K. R. Cho 1996. Expression of HPV16 E6 or E7 increases integration of foreign DNA. Oncogene 13:427-431.
    • (1996) Oncogene , vol.13 , pp. 427-431
    • Kessis, T.D.1    Connolly, D.C.2    Hedrick, L.3    Cho, K.R.4
  • 55
    • 73349125474 scopus 로고    scopus 로고
    • Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation
    • Moody, C. A., and L. A. Laimins 2009. Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation. PLoS Pathog. 5:e1000605.
    • (2009) PLoS Pathog. , vol.5 , pp. e1000605
    • Moody, C.A.1    Laimins, L.A.2
  • 56
    • 70149098944 scopus 로고    scopus 로고
    • Human papillomavirus 16 E7 oncoprotein attenuates DNA damage checkpoint control by increasing the proteolytic turnover of claspin
    • Spardy, N., K. Covella, E. Cha, E. E. Hoskins, S. I. Wells, A. Duensing, et al. 2009. Human papillomavirus 16 E7 oncoprotein attenuates DNA damage checkpoint control by increasing the proteolytic turnover of claspin. Cancer Res. 69:7022-7029.
    • (2009) Cancer Res. , vol.69 , pp. 7022-7029
    • Spardy, N.1    Covella, K.2    Cha, E.3    Hoskins, E.E.4    Wells, S.I.5    Duensing, A.6
  • 57
    • 0035849153 scopus 로고    scopus 로고
    • Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck
    • Mork, J., A. K. Lie, E. Glattre, S. Clark, G. Hallmans, E. Jellum, et al. 2001. Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck. N. Engl. J. Med. 344:1125-1131.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1125-1131
    • Mork, J.1    Lie, A.K.2    Glattre, E.3    Clark, S.4    Hallmans, G.5    Jellum, E.6
  • 60
    • 77953359433 scopus 로고    scopus 로고
    • Refining the diagnosis of oropharyngeal squamous cell carcinoma using human papillomavirus testing
    • Robinson, M., P. Sloan, and R. Shaw 2010. Refining the diagnosis of oropharyngeal squamous cell carcinoma using human papillomavirus testing. Oral Oncol. 46:492-496.
    • (2010) Oral Oncol. , vol.46 , pp. 492-496
    • Robinson, M.1    Sloan, P.2    Shaw, R.3
  • 61
    • 77955176135 scopus 로고    scopus 로고
    • p16 positive oropharyngeal squamous cell carcinoma: an entity with a favorable prognosis regardless of tumor HPV status
    • Lewis, J. S. Jr, W. L. Thorstad, R. D. Chernock, B. H. Haughey, J. H. Yip, Q. Zhang, et al. 2010. p16 positive oropharyngeal squamous cell carcinoma: an entity with a favorable prognosis regardless of tumor HPV status. Am. J. Surg. Pathol. 34:1088-1096.
    • (2010) Am. J. Surg. Pathol. , vol.34 , pp. 1088-1096
    • Lewis Jr, J.S.1    Thorstad, W.L.2    Chernock, R.D.3    Haughey, B.H.4    Yip, J.H.5    Zhang, Q.6
  • 62
    • 84861837913 scopus 로고    scopus 로고
    • HPV DNA, E6* I-mRNA expression and p16INK4A immunohistochemistry in head and neck cancer-how valid is p16INK4A as surrogate marker?
    • Hoffmann, M., S. Tribius, E. S. Quabius, H. Henry, S. Pfannenschmidt, C. Burkhardt, et al. 2012. HPV DNA, E6* I-mRNA expression and p16INK4A immunohistochemistry in head and neck cancer-how valid is p16INK4A as surrogate marker? Cancer Lett. 323:88-96.
    • (2012) Cancer Lett. , vol.323 , pp. 88-96
    • Hoffmann, M.1    Tribius, S.2    Quabius, E.S.3    Henry, H.4    Pfannenschmidt, S.5    Burkhardt, C.6
  • 63
    • 80054042271 scopus 로고    scopus 로고
    • Neil Hayes D., Couch M.E., and Kimple R.J., Association of p16INK4a overexpression with improved outcomes in young patients with squamous cell cancers of the oral tongue
    • Harris, S. L., L. B. Thorne, and W. T. Seaman 2011. Neil Hayes D., Couch M.E., and Kimple R.J., Association of p16INK4a overexpression with improved outcomes in young patients with squamous cell cancers of the oral tongue. Head Neck 33:1622-1627.
    • (2011) Head Neck , vol.33 , pp. 1622-1627
    • Harris, S.L.1    Thorne, L.B.2    Seaman, W.T.3
  • 65
    • 84864117690 scopus 로고    scopus 로고
    • p16 Immunohistochemistry as a standalone test for risk stratification in oropharyngeal squamous cell carcinoma
    • Lewis, J. S. Jr. 2012. p16 Immunohistochemistry as a standalone test for risk stratification in oropharyngeal squamous cell carcinoma. Head Neck Pathol. 6:75-82.
    • (2012) Head Neck Pathol. , vol.6 , pp. 75-82
    • Lewis Jr, J.S.1
  • 66
    • 0001115323 scopus 로고
    • Detection and typing of genital human papillomaviruses
    • in Michael A. Innis, David H. Gelfand, John J. Sninsky, Thomas J. White ed. Academic Press Inc, San Diego, CA, USA.
    • Y., T., and M. M. Manos 1990. Detection and typing of genital human papillomaviruses. Pp. 356-367 in Michael A. Innis, David H. Gelfand, John J. Sninsky, Thomas J. White ed. PCR protocols: a guide to methods and applications. Academic Press Inc, San Diego, CA, USA.
    • (1990) PCR protocols: a guide to methods and applications , pp. 356-367
    • Manos, M.M.1
  • 67
    • 0028915024 scopus 로고
    • The use of general primers GP5 and GP6 elongated at their 3′ ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR
    • De Roda Husman, A. M., J. M. Walboomers, van den Brule A. J., C. J. Meijer, and P. J. Snijders 1995. The use of general primers GP5 and GP6 elongated at their 3′ ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR. J. Gen. Virol. 76: 1057-1062.
    • (1995) J. Gen. Virol. , vol.76 , pp. 1057-1062
    • De Roda Husman, A.M.1    Walboomers, J.M.2    van den Brule, A.J.3    Meijer, C.J.4    Snijders, P.J.5
  • 68
    • 27744514003 scopus 로고    scopus 로고
    • Cervical human papillomavirus screening by PCR: advantages of targeting the E6/E7 region
    • Morris, B. J. 2005. Cervical human papillomavirus screening by PCR: advantages of targeting the E6/E7 region. Clin. Chem. Lab. Med. 43:1171-1177.
    • (2005) Clin. Chem. Lab. Med. , vol.43 , pp. 1171-1177
    • Morris, B.J.1
  • 69
    • 0029058625 scopus 로고
    • Differential sensitivities of E6 type-specific and L1 consensus primers in the detection of human papillomavirus in anal carcinoma
    • Noffsinger, A. E., L. Suzuk, Y. Z. Hui, A. A. Gal, and C. M. Fenoglio-Preiser 1995. Differential sensitivities of E6 type-specific and L1 consensus primers in the detection of human papillomavirus in anal carcinoma. Mod. Pathol. 8:509-514.
    • (1995) Mod. Pathol. , vol.8 , pp. 509-514
    • Noffsinger, A.E.1    Suzuk, L.2    Hui, Y.Z.3    Gal, A.A.4    Fenoglio-Preiser, C.M.5
  • 70
    • 31844436239 scopus 로고    scopus 로고
    • Genome variation of human papillomavirus types: phylogenetic and medical implications
    • Bernard, H. U., I. E. Calleja-Macias, and S. T. Dunn 2006. Genome variation of human papillomavirus types: phylogenetic and medical implications. Int. J. Cancer 118:1071-1076.
    • (2006) Int. J. Cancer , vol.118 , pp. 1071-1076
    • Bernard, H.U.1    Calleja-Macias, I.E.2    Dunn, S.T.3
  • 71
    • 0344837908 scopus 로고    scopus 로고
    • International proficiency study of a consensus L1 PCR assay for the detection and typing of human papillomavirus DNA: evaluation of accuracy and intralaboratory and interlaboratory agreement
    • Kornegay, J. R., M. Roger, P. O. Davies, A. P. Shepard, N. A. Guerrero, B. Lloveras, et al. 2003. International proficiency study of a consensus L1 PCR assay for the detection and typing of human papillomavirus DNA: evaluation of accuracy and intralaboratory and interlaboratory agreement. J. Clin. Microbiol. 41:1080-1086.
    • (2003) J. Clin. Microbiol. , vol.41 , pp. 1080-1086
    • Kornegay, J.R.1    Roger, M.2    Davies, P.O.3    Shepard, A.P.4    Guerrero, N.A.5    Lloveras, B.6
  • 72
    • 84864127158 scopus 로고    scopus 로고
    • HPV detection methods in head and neck cancer
    • Venuti, A., and F. Paolini 2012. HPV detection methods in head and neck cancer. Head Neck Pathol. 6:63-74.
    • (2012) Head Neck Pathol. , vol.6 , pp. 63-74
    • Venuti, A.1    Paolini, F.2
  • 73
    • 77951457224 scopus 로고    scopus 로고
    • Comparison of human papillomavirus in situ hybridization and p16 immunohistochemistry in the detection of human papillomavirus-associated head and neck cancer based on a prospective clinical experience
    • Singhi, A. D., and W. H. Westra 2010. Comparison of human papillomavirus in situ hybridization and p16 immunohistochemistry in the detection of human papillomavirus-associated head and neck cancer based on a prospective clinical experience. Cancer 116:2166-2173.
    • (2010) Cancer , vol.116 , pp. 2166-2173
    • Singhi, A.D.1    Westra, W.H.2
  • 74
    • 35648937953 scopus 로고    scopus 로고
    • A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen
    • Smeets, S. J., A. T. Hesselink, E. J. M. Speel, A. Haesevoets, P. J. Snijders, M. Pawlita, et al. 2007. A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen. Int. J. Cancer 121:2465-2472.
    • (2007) Int. J. Cancer , vol.121 , pp. 2465-2472
    • Smeets, S.J.1    Hesselink, A.T.2    Speel, E.J.M.3    Haesevoets, A.4    Snijders, P.J.5    Pawlita, M.6
  • 75
    • 79953107664 scopus 로고    scopus 로고
    • Evaluation of human papillomavirus testing for squamous cell carcinoma of the tonsil in clinical practice
    • Thavaraj, S., A. Stokes, E. Guerra, J. Bible, E. Halligan, A. Long, et al. 2011. Evaluation of human papillomavirus testing for squamous cell carcinoma of the tonsil in clinical practice. J. Clin. Pathol. 64:308-312.
    • (2011) J. Clin. Pathol. , vol.64 , pp. 308-312
    • Thavaraj, S.1    Stokes, A.2    Guerra, E.3    Bible, J.4    Halligan, E.5    Long, A.6
  • 76
    • 84899121619 scopus 로고    scopus 로고
    • Molecular mechanisms of HPV induced carcinogenesis in head and neck
    • Rampias, T., C. Sasaki, and A. Psyrri 2013. Molecular mechanisms of HPV induced carcinogenesis in head and neck. Oral Oncol. 50:356-363.
    • (2013) Oral Oncol. , vol.50 , pp. 356-363
    • Rampias, T.1    Sasaki, C.2    Psyrri, A.3
  • 77
    • 84878013899 scopus 로고    scopus 로고
    • Viral load, physical status, and E6/E7 mRNA expression of human papillomavirus in head and neck squamous cell carcinoma
    • Deng, Z., M. Hasegawa, A. Kiyuna, S. Matayoshi, T. Uehara, S. Agena, et al. 2013. Viral load, physical status, and E6/E7 mRNA expression of human papillomavirus in head and neck squamous cell carcinoma. Head Neck 35:800-808.
    • (2013) Head Neck , vol.35 , pp. 800-808
    • Deng, Z.1    Hasegawa, M.2    Kiyuna, A.3    Matayoshi, S.4    Uehara, T.5    Agena, S.6
  • 78
    • 84867116870 scopus 로고    scopus 로고
    • Viral RNA patterns and high viral load reliably define oropharynx carcinomas with active HPV16 involvement
    • Holzinger, D., M. Schmitt, G. Dyckhoff, A. Benner, M. Pawlita, and F. X. Bosch 2012. Viral RNA patterns and high viral load reliably define oropharynx carcinomas with active HPV16 involvement. Cancer Res. 72:4993-5003.
    • (2012) Cancer Res. , vol.72 , pp. 4993-5003
    • Holzinger, D.1    Schmitt, M.2    Dyckhoff, G.3    Benner, A.4    Pawlita, M.5    Bosch, F.X.6
  • 79
    • 81155161063 scopus 로고    scopus 로고
    • High-risk human papillomavirus E6/E7 mRNA detection by a novel in situ hybridization assay strongly correlates with p16 expression and patient outcomes in oropharyngeal squamous cell carcinoma
    • Ukpo, O. C., J. J. Flanagan, X.-J. Ma, Y. Luo, W. L. Thorstad, and J. S. Lewis 2011. High-risk human papillomavirus E6/E7 mRNA detection by a novel in situ hybridization assay strongly correlates with p16 expression and patient outcomes in oropharyngeal squamous cell carcinoma. Am. J. Surg. Pathol. 35:1343-1350.
    • (2011) Am. J. Surg. Pathol. , vol.35 , pp. 1343-1350
    • Ukpo, O.C.1    Flanagan, J.J.2    Ma, X.-J.3    Luo, Y.4    Thorstad, W.L.5    Lewis, J.S.6
  • 80
    • 84876414366 scopus 로고    scopus 로고
    • Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma
    • Schache, A. G., T. Liloglou, J. M. Risk, T. M. Jones, X. J. Ma, H. Wang, et al. 2013. Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma. Br. J. Cancer 108:1332-1339.
    • (2013) Br. J. Cancer , vol.108 , pp. 1332-1339
    • Schache, A.G.1    Liloglou, T.2    Risk, J.M.3    Jones, T.M.4    Ma, X.J.5    Wang, H.6
  • 81
    • 80053520906 scopus 로고    scopus 로고
    • Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination
    • Schache, A. G., T. Liloglou, J. M. Risk, A. Filia, T. M. Jones, J. Sheard, et al. 2011. Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination. Clin. Cancer Res. 17:6262-6271.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 6262-6271
    • Schache, A.G.1    Liloglou, T.2    Risk, J.M.3    Filia, A.4    Jones, T.M.5    Sheard, J.6
  • 82
    • 0036123531 scopus 로고    scopus 로고
    • Sexual behavior, human papillomavirus type 16 (HPV 16) infection, and HPV 16 seropositivity
    • Castle, P. E., T. Shields, R. Kirnbauer, M. M. Manos, R. D. Burk, A. G. Glass, et al. 2002. Sexual behavior, human papillomavirus type 16 (HPV 16) infection, and HPV 16 seropositivity. Sex. Transm. Dis. 29:182-187.
    • (2002) Sex. Transm. Dis. , vol.29 , pp. 182-187
    • Castle, P.E.1    Shields, T.2    Kirnbauer, R.3    Manos, M.M.4    Burk, R.D.5    Glass, A.G.6
  • 83
    • 0037619047 scopus 로고    scopus 로고
    • Human papillomavirus-specific antibody status in oral fluids modestly reflects serum status in human immunodeficiency virus-positive individuals
    • Cameron, J. E., I. V. Snowhite, A. K. Chaturvedi, and M. E. Hagensee 2003. Human papillomavirus-specific antibody status in oral fluids modestly reflects serum status in human immunodeficiency virus-positive individuals. Clin. Diagn. Lab. Immunol. 10:431-438.
    • (2003) Clin. Diagn. Lab. Immunol. , vol.10 , pp. 431-438
    • Cameron, J.E.1    Snowhite, I.V.2    Chaturvedi, A.K.3    Hagensee, M.E.4
  • 84
    • 79958087380 scopus 로고    scopus 로고
    • Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer
    • Anderson, K., J. Wong, G. D'Souza, A. Riemer, J. Lorch, R. Haddad, et al. 2011. Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer. Br. J. Cancer 104:1896-1905.
    • (2011) Br. J. Cancer , vol.104 , pp. 1896-1905
    • Anderson, K.1    Wong, J.2    D'Souza, G.3    Riemer, A.4    Lorch, J.5    Haddad, R.6
  • 85
    • 85006199207 scopus 로고    scopus 로고
    • Saliva as an emerging biofluid for clinical diagnosis and applications of MEMS/NEMS in salivary diagnostics
    • in K. Subramani, W. Ahmed, J. K. Hartsfield Jr., eds. Nanobiomaterials in clinical dentistry, Elsevier, Oxford, UK.
    • Punyadeera, C., and P. D. Slowey 2013. Saliva as an emerging biofluid for clinical diagnosis and applications of MEMS/NEMS in salivary diagnostics in K. Subramani, W. Ahmed, J. K. Hartsfield Jr., eds. Nanobiomaterials in clinical dentistry, Elsevier, Oxford, UK.
    • (2013)
    • Punyadeera, C.1    Slowey, P.D.2
  • 90
    • 27144487513 scopus 로고    scopus 로고
    • Feasibility of quantitative PCR-based saliva rinse screening of HPV for head and neck cancer
    • Zhao, M., E. Rosenbaum, A. L. Carvalho, W. Koch, W. Jiang, D. Sidransky, et al. 2005. Feasibility of quantitative PCR-based saliva rinse screening of HPV for head and neck cancer. Int. J. Cancer 117:605-610.
    • (2005) Int. J. Cancer , vol.117 , pp. 605-610
    • Zhao, M.1    Rosenbaum, E.2    Carvalho, A.L.3    Koch, W.4    Jiang, W.5    Sidransky, D.6
  • 91
    • 51649094603 scopus 로고    scopus 로고
    • Presence of HPV DNA in convalescent salivary rinses is an adverse prognostic marker in head and neck squamous cell carcinoma
    • Chuang, A. Y., T. C. Chuang, S. Chang, S. Zhou, S. Begum, W. H. Westra, et al. 2008. Presence of HPV DNA in convalescent salivary rinses is an adverse prognostic marker in head and neck squamous cell carcinoma. Oral Oncol. 44:915-919.
    • (2008) Oral Oncol. , vol.44 , pp. 915-919
    • Chuang, A.Y.1    Chuang, T.C.2    Chang, S.3    Zhou, S.4    Begum, S.5    Westra, W.H.6
  • 92
    • 58149269562 scopus 로고    scopus 로고
    • Oral human papillomavirus infection before and after treatment for human papillomavirus 16-positive and human papillomavirus 16-negative head and neck squamous cell carcinoma
    • Agrawal, Y., W. M. Koch, W. Xiao, W. H. Westra, A. L. Trivett, D. E. Symer, et al. 2008. Oral human papillomavirus infection before and after treatment for human papillomavirus 16-positive and human papillomavirus 16-negative head and neck squamous cell carcinoma. Clin. Cancer Res. 14:7143-7150.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 7143-7150
    • Agrawal, Y.1    Koch, W.M.2    Xiao, W.3    Westra, W.H.4    Trivett, A.L.5    Symer, D.E.6
  • 95
    • 80052605310 scopus 로고    scopus 로고
    • Associations between oral HPV16 infection and cytopathology: evaluation of an oropharyngeal "pap-test equivalent" in high-risk populations
    • Fakhry, C., B. T. Rosenthal, D. P. Clark, and M. L. Gillison 2011. Associations between oral HPV16 infection and cytopathology: evaluation of an oropharyngeal "pap-test equivalent" in high-risk populations. Cancer Prev. Res. 4:1378-1384.
    • (2011) Cancer Prev. Res. , vol.4 , pp. 1378-1384
    • Fakhry, C.1    Rosenthal, B.T.2    Clark, D.P.3    Gillison, M.L.4
  • 97
    • 84898803843 scopus 로고    scopus 로고
    • Human papillomavirus prevalence is high in oral samples of patients with tonsillar and base of tongue cancer
    • Nordfors, C., A. Vlastos, J. Du, A. Ährlund-Richter, N. Tertipis, N. Grün, et al. 2014. Human papillomavirus prevalence is high in oral samples of patients with tonsillar and base of tongue cancer. Oral Oncol. 50:491-497.
    • (2014) Oral Oncol. , vol.50 , pp. 491-497
    • Nordfors, C.1    Vlastos, A.2    Du, J.3    Ährlund-Richter, A.4    Tertipis, N.5    Grün, N.6
  • 99
    • 8644249908 scopus 로고    scopus 로고
    • Human papillomavirus is more common in base of tongue than in mobile tongue cancer and is a favorable prognostic factor in base of tongue cancer patients
    • Dahlgren, L., H. M. Dahlstrand, D. Lindquist, A. Högmo, L. Björnestål, J. Lindholm, et al. 2004. Human papillomavirus is more common in base of tongue than in mobile tongue cancer and is a favorable prognostic factor in base of tongue cancer patients. Int. J. Cancer 112:1015-1019.
    • (2004) Int. J. Cancer , vol.112 , pp. 1015-1019
    • Dahlgren, L.1    Dahlstrand, H.M.2    Lindquist, D.3    Högmo, A.4    Björnestål, L.5    Lindholm, J.6
  • 100
    • 84907429580 scopus 로고    scopus 로고
    • De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma: a systematic review and meta-analysis of current clinical trials
    • Masterson, L., D. Moualed, Z. W. Liu, J. E. F. Howard, R. C. Dwivedi, J. R. Tysome, et al. 2014. De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma: a systematic review and meta-analysis of current clinical trials. Eur. J. Cancer 50:2636-2648.
    • (2014) Eur. J. Cancer , vol.50 , pp. 2636-2648
    • Masterson, L.1    Moualed, D.2    Liu, Z.W.3    Howard, J.E.F.4    Dwivedi, R.C.5    Tysome, J.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.