Tumor suppressor p16INK4A is necessary for survival of cervical carcinoma cell lines

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 40, 2013, Pages 16175-16180

  McLaughlin Drubin, Margaret E ^a,b   Park, Donglim ^b   Munger, Karl ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Biomarker; Cancer therapy; Synthetic lethality

Indexed keywords

ARGININE; CASPASE 3; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYSTEINE; HISTONE DEMETHYLASE; KDM6B PROTEIN; PROCASPASE 3; PROTEIN E7; RETROVIRUS VECTOR; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; KDM6B PROTEIN, HUMAN; ONCOGENE PROTEIN E7, HUMAN PAPILLOMAVIRUS TYPE 16; TUMOR SUPPRESSOR PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL AGING; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; EPIGENETIC REPRESSION; GENE MUTATION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 18; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN INDUCTION; UTERINE CERVIX CARCINOMA; CARCINOMA; FEMALE; GENETICS; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE; UTERINE CERVIX TUMOR;

CARCINOMA; CELL LINE, TUMOR; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FEMALE; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; PAPILLOMAVIRUS E7 PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR SUPPRESSOR PROTEINS; UTERINE CERVICAL NEOPLASMS;

EID: 84885076128     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1310432110     Document Type: Article

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