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Volumn 50, Issue 15, 2014, Pages 2636-2648

De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma: A systematic review and meta-analysis of current clinical trials

Author keywords

De escalation of treatments; Human papillomavirus; Oropharyngeal carcinoma

Indexed keywords

CARCINOMA, SQUAMOUS CELL; CHEMORADIOTHERAPY; CLINICAL PROTOCOL; COMPLICATION; DRUG EFFECTS; HUMAN; META ANALYSIS; OROPHARYNGEAL NEOPLASMS; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; PHYSIOLOGY; PROCEDURES; RADIATION RESPONSE; RANDOMIZED CONTROLLED TRIAL (TOPIC); SURVIVAL; TREATMENT OUTCOME; VIROLOGY;

EID: 84907429580     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2014.07.001     Document Type: Review
Times cited : (244)

References (44)
  • 1
    • 84861648384 scopus 로고    scopus 로고
    • Global burden of cancers attributable to infections in 2008: A review and synthetic analysis
    • C. de Martel, F. Ferlay, and S. Franceschi Global burden of cancers attributable to infections in 2008: a review and synthetic analysis Lancet Oncol 13 2012 607 615
    • (2012) Lancet Oncol , vol.13 , pp. 607-615
    • De Martel, C.1    Ferlay, F.2    Franceschi, S.3
  • 2
    • 84869492886 scopus 로고    scopus 로고
    • Global burden of cancer in 2008: A systematic analysis of disability-adjusted life-years in 12 world regions
    • I. Soerjomataram, J. Lortet-Tieulent, and D.M. Parkin Global burden of cancer in 2008: a systematic analysis of disability-adjusted life-years in 12 world regions Lancet Oncol 380 2012 1840 1850
    • (2012) Lancet Oncol , vol.380 , pp. 1840-1850
    • Soerjomataram, I.1    Lortet-Tieulent, J.2    Parkin, D.M.3
  • 3
    • 10044248559 scopus 로고    scopus 로고
    • Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity
    • M.L. Gillison Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity Semin Oncol 31 2004 744 754
    • (2004) Semin Oncol , vol.31 , pp. 744-754
    • Gillison, M.L.1
  • 5
    • 84876062521 scopus 로고    scopus 로고
    • The prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer: A systematic review and meta-analysis of trends by time and region
    • H. Mehanna, T. Beech, and T. Nicholson The prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer: a systematic review and meta-analysis of trends by time and region Head Neck 35 2012 747 755
    • (2012) Head Neck , vol.35 , pp. 747-755
    • Mehanna, H.1    Beech, T.2    Nicholson, T.3
  • 6
    • 84907426306 scopus 로고    scopus 로고
    • Oropharyngeal cancer
    • N. Roland, V. Paleri, K. MacKenzie, P. Clarke, J. Homer, P. Pracy, British Association of Otorhinolaryngology, Head and Neck Surgery London
    • H. Mehanna Oropharyngeal cancer N. Roland, V. Paleri, K. MacKenzie, P. Clarke, J. Homer, P. Pracy, Head and neck cancer 2011 British Association of Otorhinolaryngology, Head and Neck Surgery London 137 146
    • (2011) Head and Neck Cancer , pp. 137-146
    • Mehanna, H.1
  • 7
    • 80055089099 scopus 로고    scopus 로고
    • Prevalence and impact of complications on outcomes in patients hospitalized for oral and oropharyngeal cancer treatment
    • M.K. Lee, R.P. Nalliah, and M.K. Kim Prevalence and impact of complications on outcomes in patients hospitalized for oral and oropharyngeal cancer treatment Oral Surg Oral Med Oral Pathol Oral Radiol Endod 112 2011 581 591
    • (2011) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.112 , pp. 581-591
    • Lee, M.K.1    Nalliah, R.P.2    Kim, M.K.3
  • 8
    • 84857065859 scopus 로고    scopus 로고
    • Prevalence of oral HPV infection in the United States, 2009-2010
    • M.L. Gillison, T. Broutian, and R.K. Pickard Prevalence of oral HPV infection in the United States, 2009-2010 JAMA 307 2012 693 703
    • (2012) JAMA , vol.307 , pp. 693-703
    • Gillison, M.L.1    Broutian, T.2    Pickard, R.K.3
  • 9
    • 77954190940 scopus 로고    scopus 로고
    • Human papillomavirus and survival of patients with oropharyngeal cancer
    • K. Ang, J. Harris, and R. Wheeler Human papillomavirus and survival of patients with oropharyngeal cancer N Engl J Med 363 2010 24 35
    • (2010) N Engl J Med , vol.363 , pp. 24-35
    • Ang, K.1    Harris, J.2    Wheeler, R.3
  • 10
    • 80053520906 scopus 로고    scopus 로고
    • Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: Sensitivity, specificity, and prognostic discrimination
    • A.G. Schache, T. Liloglou, J.M. Risk, A. Filia, T.M. Jones, and J. Sheard Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination Clin Cancer Res 17 2011 6262 6271
    • (2011) Clin Cancer Res , vol.17 , pp. 6262-6271
    • Schache, A.G.1    Liloglou, T.2    Risk, J.M.3    Filia, A.4    Jones, T.M.5    Sheard, J.6
  • 11
    • 63449140288 scopus 로고    scopus 로고
    • The changing face of head and neck cancer in the 21st century: The impact of HPV on the epidemiology and pathology of oral cancer
    • W.H. Westra The changing face of head and neck cancer in the 21st century: the impact of HPV on the epidemiology and pathology of oral cancer Head Neck Pathol 3 2009 78 81
    • (2009) Head Neck Pathol , vol.3 , pp. 78-81
    • Westra, W.H.1
  • 12
    • 0021203931 scopus 로고
    • Correlation between response to cisplatinum-combination chemotherapy and subsequent radiotherapy in previously untreated patients with advanced squamous cell cancers of the head and neck
    • J.F. Ensley, J.R. Jacobs, and A. Weaver Correlation between response to cisplatinum-combination chemotherapy and subsequent radiotherapy in previously untreated patients with advanced squamous cell cancers of the head and neck Clin Cancer Res 54 1984 811 814
    • (1984) Clin Cancer Res , vol.54 , pp. 811-814
    • Ensley, J.F.1    Jacobs, J.R.2    Weaver, A.3
  • 13
    • 79958272187 scopus 로고    scopus 로고
    • Transoral laser microsurgery as primary treatment for advanced-stage oropharyngeal cancer: A United States multicenter study
    • B.H. Haughey, M.L. Hinni, and J.R. Salassa Transoral laser microsurgery as primary treatment for advanced-stage oropharyngeal cancer: a United States multicenter study Head Neck 33 2011 1683 1694
    • (2011) Head Neck , vol.33 , pp. 1683-1694
    • Haughey, B.H.1    Hinni, M.L.2    Salassa, J.R.3
  • 14
    • 73249143536 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
    • J.A. Bonner, P.M. Harari, J. Giralt, R.B. Cohen, C.U. Jones, and R.K. Sur Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival Lancet Oncol 11 2010 21 28
    • (2010) Lancet Oncol , vol.11 , pp. 21-28
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3    Cohen, R.B.4    Jones, C.U.5    Sur, R.K.6
  • 15
    • 80053368876 scopus 로고    scopus 로고
    • A randomized phase III trial (RTOG 0522) of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III-IV head and neck squamous cell carcinomas
    • K.K. Ang, and Q.E. Zhang A randomized phase III trial (RTOG 0522) of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III-IV head and neck squamous cell carcinomas J Clin Oncol 29 2011 5500
    • (2011) J Clin Oncol , vol.29 , pp. 5500
    • Ang, K.K.1    Zhang, Q.E.2
  • 16
    • 80255134559 scopus 로고    scopus 로고
    • Concurrent cisplatin and radiation versus cetuximab and radiation for locally advanced head and neck cancer
    • L. Koutcher, E. Sherman, and M. Fury Concurrent cisplatin and radiation versus cetuximab and radiation for locally advanced head and neck cancer Int J Radiat Oncol Biol Phys 81 2011 915 922
    • (2011) Int J Radiat Oncol Biol Phys , vol.81 , pp. 915-922
    • Koutcher, L.1    Sherman, E.2    Fury, M.3
  • 17
    • 84879785532 scopus 로고    scopus 로고
    • Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): An open-label phase 3 randomised trial
    • J.B. Vermorken, J. Stöhlmacher-Williams, and I. Davidenko Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial Lancet Oncol 14 2013 697 710
    • (2013) Lancet Oncol , vol.14 , pp. 697-710
    • Vermorken, J.B.1    Stöhlmacher-Williams, J.2    Davidenko, I.3
  • 18
    • 66949128922 scopus 로고    scopus 로고
    • Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomized trials and 17,346 patients
    • J.P. Pignon, A. Maître, E. Maillard, and J. Bourhis Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomized trials and 17,346 patients Radiother Oncol 92 2009 4 14
    • (2009) Radiother Oncol , vol.92 , pp. 4-14
    • Pignon, J.P.1    Maître, A.2    Maillard, E.3    Bourhis, J.4
  • 19
    • 49249095295 scopus 로고    scopus 로고
    • EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer
    • B. Kumar, K.G. Cordell, and J.S. Lee EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer J Clin Oncol 26 2008 128 137
    • (2008) J Clin Oncol , vol.26 , pp. 128-137
    • Kumar, B.1    Cordell, K.G.2    Lee, J.S.3
  • 20
    • 77954213063 scopus 로고    scopus 로고
    • Relationships between epidermal growth factor receptor expression and human papillomavirus status as markers of prognosis in oropharyngeal cancer
    • A. Hong, T. Dobbins, and C.S. Lee Relationships between epidermal growth factor receptor expression and human papillomavirus status as markers of prognosis in oropharyngeal cancer Eur J Cancer 46 2010 2088 2096
    • (2010) Eur J Cancer , vol.46 , pp. 2088-2096
    • Hong, A.1    Dobbins, T.2    Lee, C.S.3
  • 21
    • 84884691303 scopus 로고    scopus 로고
    • The Cancer Genome Atlas integrated analysis of genome alterations in squamous cell carcinoma of the head and neck
    • abstr 6009
    • D.N. Hayes, J.R. Grandis, and A.K. El-Naggar The Cancer Genome Atlas integrated analysis of genome alterations in squamous cell carcinoma of the head and neck Proc Am Soc Clin Oncol 31 Suppl. 2013 abstr 6009
    • (2013) Proc Am Soc Clin Oncol , vol.31 , Issue.SUPPL.
    • Hayes, D.N.1    Grandis, J.R.2    El-Naggar, A.K.3
  • 23
    • 10044289431 scopus 로고    scopus 로고
    • Dysphagia and aspiration after chemoradiotherapy for head and neck cancer: Which anatomic structures are affected and can they be spared by IMRT?
    • A. Eisbruch, M. Schwartz, and C. Rasch Dysphagia and aspiration after chemoradiotherapy for head and neck cancer: which anatomic structures are affected and can they be spared by IMRT? Int J Radiat Oncol Biol Phys 60 2004 1425 1439
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , pp. 1425-1439
    • Eisbruch, A.1    Schwartz, M.2    Rasch, C.3
  • 24
    • 34547404180 scopus 로고    scopus 로고
    • Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: Early dose-effect relationships for the swallowing structures
    • F.Y. Feng, H.M. Kim, and T.H. Lyden Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: early dose-effect relationships for the swallowing structures Radiat Oncol Biol Phys 68 2007 1289 1298
    • (2007) Radiat Oncol Biol Phys , vol.68 , pp. 1289-1298
    • Feng, F.Y.1    Kim, H.M.2    Lyden, T.H.3
  • 25
    • 34548392333 scopus 로고    scopus 로고
    • Dysphagia disorders in patients with cancer of the oropharynx are significantly affected by the radiation therapy dose to the superior and middle constrictor muscle: A dose-effect relationship
    • P.C. Levendag, D.N. Teguh, and P. Voet Dysphagia disorders in patients with cancer of the oropharynx are significantly affected by the radiation therapy dose to the superior and middle constrictor muscle: a dose-effect relationship Radiother Oncol 85 2007 64 73
    • (2007) Radiother Oncol , vol.85 , pp. 64-73
    • Levendag, P.C.1    Teguh, D.N.2    Voet, P.3
  • 26
    • 84862829059 scopus 로고    scopus 로고
    • Outcomes of HPV-related oropharyngeal cancer patients treated by radiotherapy alone using altered fractionation
    • B. O'Sullivan, and S.H. Huang Outcomes of HPV-related oropharyngeal cancer patients treated by radiotherapy alone using altered fractionation Radiother Oncol 103 2012 49 56
    • (2012) Radiother Oncol , vol.103 , pp. 49-56
    • O'Sullivan, B.1    Huang, S.H.2
  • 27
    • 84863230211 scopus 로고    scopus 로고
    • Transcriptional profiling by sequencing of oropharyngeal cancer
    • R.R. Laborde, V.W. Wang, and T.M. Smith Transcriptional profiling by sequencing of oropharyngeal cancer Mayo Clin Proc 87 2012 226 232
    • (2012) Mayo Clin Proc , vol.87 , pp. 226-232
    • Laborde, R.R.1    Wang, V.W.2    Smith, T.M.3
  • 28
    • 84892948376 scopus 로고    scopus 로고
    • Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer
    • M.J. Ward, S.M. Thirdborough, and T. Mellows Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer Br J Cancer 110 2014 489 500
    • (2014) Br J Cancer , vol.110 , pp. 489-500
    • Ward, M.J.1    Thirdborough, S.M.2    Mellows, T.3
  • 29
    • 79960935331 scopus 로고    scopus 로고
    • Transoral robotic resection and reconstruction for head and neck cancer
    • E.M. Genden, T. Kotz, and C.C. Tong Transoral robotic resection and reconstruction for head and neck cancer Laryngoscope 121 2011 1668 1674
    • (2011) Laryngoscope , vol.121 , pp. 1668-1674
    • Genden, E.M.1    Kotz, T.2    Tong, C.C.3
  • 30
    • 84907438765 scopus 로고    scopus 로고
    • Temporal regression of cervical lymph node in N2-N3 head-and-neck cancer treated with primary radiation therapy +/- chemotherapy: Stratified by HPV status
    • S. Huang, and B. O'Sullivan Temporal regression of cervical lymph node in N2-N3 head-and-neck cancer treated with primary radiation therapy +/- chemotherapy: stratified by HPV status Int J Radiat Oncol Biol Phys 1 2012 S205
    • (2012) Int J Radiat Oncol Biol Phys , vol.1 , pp. 205
    • Huang, S.1    O'Sullivan, B.2
  • 31
    • 0030916838 scopus 로고    scopus 로고
    • Expanded application of selective neck dissection with regard to nodal status
    • P.K. Pellitteri, K.T. Robbins, and T. Neuman Expanded application of selective neck dissection with regard to nodal status Head Neck 19 1997 260 265
    • (1997) Head Neck , vol.19 , pp. 260-265
    • Pellitteri, P.K.1    Robbins, K.T.2    Neuman, T.3
  • 32
    • 32944464047 scopus 로고    scopus 로고
    • Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma
    • R.J. Slebos, Y. Yi, and K. Ely Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma Clin Cancer Res 12 2006 701 709
    • (2006) Clin Cancer Res , vol.12 , pp. 701-709
    • Slebos, R.J.1    Yi, Y.2    Ely, K.3
  • 33
    • 84875990922 scopus 로고    scopus 로고
    • The HPV16 E6 oncoprotein causes prolonged receptor protein tyrosine kinase signaling and enhances internalization of phosphorylated receptor species
    • J.M. Spangle, and K. Munger The HPV16 E6 oncoprotein causes prolonged receptor protein tyrosine kinase signaling and enhances internalization of phosphorylated receptor species PLoS Pathog 9 2013 e1003237
    • (2013) PLoS Pathog , vol.9 , pp. 1003237
    • Spangle, J.M.1    Munger, K.2
  • 34
    • 84897101976 scopus 로고    scopus 로고
    • Impact of tumor HPV status on outcome in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck receiving chemotherapy with or without cetuximab: Retrospective analysis of the phase III EXTREME trial
    • J.B. Vermorken, A. Psyrri, and R. Mesia Impact of tumor HPV status on outcome in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck receiving chemotherapy with or without cetuximab: retrospective analysis of the phase III EXTREME trial Ann Oncol 25 2014 801 807
    • (2014) Ann Oncol , vol.25 , pp. 801-807
    • Vermorken, J.B.1    Psyrri, A.2    Mesia, R.3
  • 35
    • 84875475811 scopus 로고    scopus 로고
    • Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
    • S. Lyford-Pike, S. Peng, and G.D. Young Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma Clin Cancer Res 73 2013 1733 1741
    • (2013) Clin Cancer Res , vol.73 , pp. 1733-1741
    • Lyford-Pike, S.1    Peng, S.2    Young, G.D.3
  • 37
    • 84880259398 scopus 로고    scopus 로고
    • Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers
    • V.W. Lui, M.L. Hedberg, and H. Li Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers Cancer Discov 3 2013 761 769
    • (2013) Cancer Discov , vol.3 , pp. 761-769
    • Lui, V.W.1    Hedberg, M.L.2    Li, H.3
  • 38
    • 84890275508 scopus 로고    scopus 로고
    • PIK3CA, HRAS and PTEN in human papillomavirus positive oropharyngeal squamous cell carcinoma
    • S.I. Chiosea, J.R. Grandis, and V.W. Lui PIK3CA, HRAS and PTEN in human papillomavirus positive oropharyngeal squamous cell carcinoma BMC Cancer 13 2013 602
    • (2013) BMC Cancer , vol.13 , pp. 602
    • Chiosea, S.I.1    Grandis, J.R.2    Lui, V.W.3
  • 40
    • 77953203518 scopus 로고    scopus 로고
    • P16 INK4A overexpression is frequently detected in tumour-free tonsil tissue without association with HPV
    • B. Klingenberg, H.C. Hafkamp, and A. Haesevoets P16 INK4A overexpression is frequently detected in tumour-free tonsil tissue without association with HPV Histopathology 56 2010 957 967
    • (2010) Histopathology , vol.56 , pp. 957-967
    • Klingenberg, B.1    Hafkamp, H.C.2    Haesevoets, A.3
  • 42
    • 77957955293 scopus 로고    scopus 로고
    • Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial
    • D. Rischin, and R.J. Young Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial J Clin Oncol 28 2010 4142 4148
    • (2010) J Clin Oncol , vol.28 , pp. 4142-4148
    • Rischin, D.1    Young, R.J.2
  • 43
    • 79955514313 scopus 로고    scopus 로고
    • Survival and human papillomavirus in oropharynx cancer in TAX 324: A subset analysis from an international phase III trial
    • M.R. Posner, J.H. Lorch, and O. Goloubeva Survival and human papillomavirus in oropharynx cancer in TAX 324: a subset analysis from an international phase III trial Ann Oncol 22 2011 1071 1077
    • (2011) Ann Oncol , vol.22 , pp. 1071-1077
    • Posner, M.R.1    Lorch, J.H.2    Goloubeva, O.3
  • 44
    • 84863975396 scopus 로고    scopus 로고
    • Tobacco smoking and increased risk of death and progression for patients with p16-positive and p16-negative oropharyngeal cancer
    • M.L. Gillison, Q. Zhang, and R. Jordan Tobacco smoking and increased risk of death and progression for patients with p16-positive and p16-negative oropharyngeal cancer J Clin Oncol 10 2012 2102 2111
    • (2012) J Clin Oncol , vol.10 , pp. 2102-2111
    • Gillison, M.L.1    Zhang, Q.2    Jordan, R.3


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