Guttiferone K suppresses cell motility and metastasis of hepatocellular carcinoma by restoring aberrantly reduced profilin 1

Oncotarget

Volumn 7, Issue 35, 2016, Pages 56650-56663

  Shen, Kaikai ^a   Xi, Zhichao ^a   Xie, Jianling ^c   Wang, Hua ^d   Xie, Chanlu ^e   Lee, C Soon ^e,f   Fahey, Paul ^e   Dong, Qihan ^e,f,g   Xu, Hongxi ^a,b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery   (China)

^c SOUTH AUSTRALIAN HEALTH AND MEDICAL RESEARCH INSTITUTE   (Australia)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^e UNIVERSITY OF WESTERN SYDNEY   (Australia)

^f UNIVERSITY OF SYDNEY   (Australia)

^g ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

Actin; Cancer metastasis; Guttiferone K; Hepatocellular carcinoma; Profilin1

Indexed keywords

ANTINEOPLASTIC AGENT; F ACTIN; GUTTIFERONE K; PROFILIN; PROFILIN 1; UNCLASSIFIED DRUG; ACTIN; BENZOPHENONE DERIVATIVE; PFN1 PROTEIN, HUMAN; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MOTILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; LUNG METASTASIS; MALE; METASTASIS INHIBITION; MIGRATION INHIBITION; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; ADULT; AGED; ANIMAL; BAGG ALBINO MOUSE; CELL MOTION; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; FEMALE; GARCINIA; HEP-G2 CELL LINE; LIVER TUMOR; METABOLISM; METASTASIS; MIDDLE AGED; PROTEOMICS; TREATMENT OUTCOME; TUMOR CELL LINE; TUMOR INVASION;

ACTINS; ADULT; AGED; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BENZOPHENONES; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MOVEMENT; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; GARCINIA; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PLANT EXTRACTS; PROFILINS; PROTEOMICS; TREATMENT OUTCOME;

EID: 84984903670     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.10992     Document Type: Article

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