The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6

Nature

Volumn 536, Issue 7617, 2016, Pages 464-468

  Küffer, Alexander ^a   Lakkaraju, Asvin K K ^a   Mogha, Amit ^b   Petersen, Sarah C ^b   Airich, Kristina ^a   Doucerain, Cédric ^a   Marpakwar, Rajlakshmi ^a   Bakirci, Pamela ^a   Senatore, Assunta ^a   Monnard, Arnaud ^a   Schiavi, Carmen ^a   Nuvolone, Mario ^a   Grosshans, Bianka ^c   Hornemann, Simone ^a   Bassilana, Frederic ^c   Monk, Kelly R ^b   Aguzzi, Adriano ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADGRG6 PROTEIN; ALANINE; COLLAGEN TYPE 4; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; LYSINE; MYELIN; MYELIN BASIC PROTEIN; PRION PROTEIN; UNCLASSIFIED DRUG; GPR126 PROTEIN, MOUSE; GPR126 PROTEIN, ZEBRAFISH; LIGAND; PEPTIDE FRAGMENT; PRION; PRNP PROTEIN, MOUSE; ZEBRAFISH PROTEIN;

CELLS AND CELL COMPONENTS; CYPRINID; GENE; GENE EXPRESSION; HOMEOSTASIS; LIGAND; MUTATION; PHYSIOLOGY; PROTEIN; RODENT;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION CAMP; CONTROLLED STUDY; DEMYELINATION; FEMALE; HEART; HEK293 CELL LINE; HUMAN; HUMAN CELL; MALE; MOUSE; MYELINATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHWANN CELL; SCIATIC NERVE; ZEBRA FISH; AGONISTS; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; DEFICIENCY; DEMYELINATING DISEASE; DRUG EFFECTS; GENETICS; HOMEOSTASIS; METABOLISM; MOLECULAR GENETICS; MYELIN SHEATH; PHARMACOLOGY; PLIABILITY; PRION; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE;

DANIO RERIO; MUS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; COLLAGEN TYPE IV; CYCLIC AMP; DEMYELINATING DISEASES; FEMALE; HEK293 CELLS; HOMEOSTASIS; HUMANS; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; MYELIN SHEATH; PEPTIDE FRAGMENTS; PLIABILITY; PRIONS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED; SCHWANN CELLS; SCIATIC NERVE; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84984890582     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature19312     Document Type: Article

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