The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development

Genes and Development

Volumn 17, Issue 11, 2003, Pages 1380-1391

  Jaegle, Martine ^a   Ghazvini, Mehrnaz ^a   Mandemakers, Wim ^a,b   Piirsoo, Marko ^a,c   Driegen, Siska ^a   Levavasseur, Françoise ^a   Raghoenath, Smiriti ^a   Grosveld, Frank ^a   Meijer, Dies ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF CHEMICAL PHYSICS AND BIOPHYSICS   (Estonia)

Author keywords

Myelin; Nerve development; POU domain; Schwann cell

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 6; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BRN2; TRANSCRIPTION FACTOR POU; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; EMBRYO; GENE ACTIVATION; GENE DISRUPTION; GENE OVEREXPRESSION; MOUSE; MYELINATION; NERVE GROWTH; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCHWANN CELL;

ANIMALIA;

EID: 0038623319     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.258203     Document Type: Article

References (42)

1. Ambrosetti, D.C., Basilico, C., and Dailey, L. 1997. Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites. Mol. Cell. Biol. 17: 6321-6329.
2. Andersen, B., Weinberg, W.C., Rennekampff, O., McEvilly, R.J., Bermingham Jr., J.R., Hooshmand, F., Vasilyev, V., Hansbrough, J.F., Pittelkow, M.R., Yuspa, S.H., et al. 1997. Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/ SCIP in epidermal differentiation. Genes & Dev. 11: 1873-1884.
3. Archelos, J.J., Roggenbuck, K., Schneider-Schaulies, J., Linington, C., Toyka, K.V., and Hartung, H.P. 1993. Production and characterization of monoclonal antibodies to the extracellular domain of PO. J. Neurosci. Res. 35: 46-53.
4. Arroyo, E.J. and Scherer, S.S. 2000. On the molecular architecture of myelinated fibers. Histochem. Cell. Biol. 113: 1-18.
5. Arroyo, E.J., Bermingham Jr., J.R., Rosenfeld, M.G., and Scherer, S.S. 1998. Promyelinating Schwann cells express Tst-1/ SCIP/Oct-6. J. Neurosci. 18: 7891-7902.
6. Bermingham, J.R., Scherer, S.S., O'Connell, S., Arroyo, E., Kalla, K.A., Powell, F.L., and Rosenfeld, M.G. 1996. Tst-1/Oct-6/ SCIP regulates a unique step in peripheral myelination and is required for normal respiration. Genes & Dev. 10: 1751-1762.
7. Bitgood, M.J. and McMahon, A.P. 1995. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev. Biol. 172: 126-138.
8. Blanchard, A.D., Sinanan, A., Parmantier, E., Zwart, R., Broos, L., Meijer, D., Meier, C., Jessen, K.R., and Mirsky, R. 1996. Oct-6 (SCIP/Tst-1) is expressed in Schwann cell precursors, embryonic Schwann cells, and postnatal myelinating Schwann cells: Comparison with Oct-1, Krox-20, and Pax-3. J. Neurosci. Res. 46: 630-640.
9. Britsch, S., Goerich, D.E., Riethmacher, D., Peirano, R.I., Rossner, M., Nave, K.A., Birchmeier, C., and Wegner, M. 2001. The transcription factor Sox10 is a key regulator of peripheral glial development. Genes & Dev. 15: 66-78.
10. Estable-Puig, J.F., Bauer, W.C., and Blumberg, J.M. 1965. Technical note; paraphenylenediamine staining of osmium-fixed plastic embedded tissue for light and phase microscopy. J. Neuropathol. Exp. Neurol. 24: 531-536.
11. Fields, R.D. and Stevens-Graham, B. 2002. New insights into neuron-glia communication. Science 298: 556-562.
12. Ghazvini, M., Mandemakers, W., Jaegle, M., Piirsoo, M., Driegen, S., Koutsourakis, M., Smit, X., Grosveld, F., and Meijer, D. 2002. A cell type-specific allele of the POU gene Oct-6 reveals Schwann cell autonomous function in nerve development and regeneration. EMBO J. 21: 4612-4620.
13. Ghislain, J., Desmarquet-Trin-Dinh, C., Jaegle, M., Meijer, D., Charnay, P., and Frain, M. 2002. Characterization of cisacting sequences reveals a biphasic, axon-dependent regulation of Krox20 during Schwann cell development. Development 129: 155-166.
14. Hudson, L.D. 2001. Control of gene expression by oligodendrocytes. In Glial cell development (eds. K.R. Jessen, W.D. Richardson), pp. 209-222. Oxford University Press, Oxford, UK.
15. Ilia, M., Beasley, C., Meijer, D., Kerwin, R., Cotter, D., Everall, I., and Price, J. 2002. Expression of Oct-6, a POU III domain transcription factor, in schizophrenia. Am. J. Psychiatry 159: 1174-1182.
16. Jaegle, M. and Meijer, D. 1998. Role of Oct-6 in Schwann cell differentiation. Microsc. Res. Tech. 41: 372-378.
17. Jaegle, M., Mandemakers, W., Broos, L., Zwart, R., Karis, A., Visser, P., Grosveld, F., and Meijer, D. 1996. The POU factor Oct-6 and Schwann cell differentiation. Science 273: 507-510.
18. Kuhlbrodt, K., Herbarth, B., Sock, E., Enderich, J., HermansBorgmeyer, I., and Wegner, M. 1998a. Cooperative function of POU proteins and SOX proteins in glial cells. J. Biol. Chem. 273: 16050-16057.
19. Kuhlbrodt, K., Herbarth, B., Sock, S., Hermans-Borgmeyer, I., and Wegner, M. 1998b. Sox 10, a novel transcriptional modulator in glial cells. J. Neurosci. 18: 237-250.
20. Kuhn, R., Monuki, E.S., and Lemke, G. 1991. The gene encoding the transcription factor SCIP has features of an expressed retroposon. Mol. Cell. Biol. 11: 4642-4650.
21. Le Douarin, N.M. and Kalcheim, C. 1999. The neural crest, pp. 328-335. Cambridge University Press, Cambridge, UK.
22. Levavasseur, F., Mandemakers, W., Visser, P., Broos, L., Grosveld, F., Zivkovic, D., and Meijer, D. 1998. Comparison of sequence and function of the Oct-6 genes in zebrafish, chicken, and mouse. Mech. Dev. 74: 89-98.
23. Mandemakers, W., Zwart, R., Jaegle, M., Walbeehm, E., Visser, P., Grosveld, F., and Meijer, D. 2000. A distal Schwann cellspecific enhancer mediates axonal regulation of the Oct-6 transcription factor during peripheral nerve development and regeneration. EMBO J. 19: 2992-3003.
24. McEvilly, R.J., de Diaz, M.O., Schonemann, M.D., Hooshmand, F., and Rosenfeld, M.G. 2002. Transcriptional regulation of cortical neuron migration by POU domain factors. Science 295: 1528-1532.
25. Meijer, D., Graus, A., Kraay, R., Langeveld, A., Mulder, M.P., and Grosveld, G. 1990. The octamer binding factor Oct6: cDNA cloning and expression in early embryonic cells. Nucleic Acids Res. 18: 7357-7365.
26. Meijer, D., Graus, A., and Grosveld, G. 1992. Mapping the transactivation domain of the Oct6 POU transcription factor. Nucleic Acids Res. 20: 2241-2247.
27. Mirsky, R., Jessen, K.R., Brennan, A., Parkinson, D., Dong, Z., Meier, C., Parmantier, E., and Lawson, D. 2002. Schwann cells as regulators of nerve development. J. Physiol. Paris 96: 17-24.
28. Nagarajan, R., Svaren, J., Le, N., Araki, T., Watson, M., and Milbrandt, J. 2001. EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression. Neuron 30: 355-368.
29. Nakai, S., Kawano, H., Yudate, T., Nishi, M., Kuno, J., Nagata, A., Jishage, K., Hamada, H., Fujii, H., Kawamura, K., et al. 1995. The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse. Genes & Dev. 9: 3109-3121.
30. Nickols, J.C., Valentine, W., Kanwal, S., and Carter, B.D. 2003. Activation of the transcription factor NF-κB in Schwann cells is required for peripheral myelin formation. Nat. Neurosci. 6: 161-167.
31. Richardson, W.D. 2001. Oligodendrocyte development. In Glial cell development (eds. K.R. Jessen and W.D. Richardson), pp. 21-54. Oxford University Press, Oxford.
32. Ryan, A.K. and Rosenfeld, M.G. 1997. POU domain family values: Flexibility, partnerships, and developmental codes. Genes & Dev. 11: 1207-1225.
33. Scherer, S.S., Wang, D.Y., Kuhn, R., Lemke, G., Wrabetz, L., and Kamholz, J. 1994. Axons regulate Schwann cell expression of the POU transcription factor SCIP. J. Neurosci. 14: 1930-1942.
34. Schonemann, M.D., Ryan, A.K., McEvilly, R.J., O'Connell, S.M., Arias, C.A., Kalla, K.A., Li, P., Sawchenko, P.E., and Rosenfeld, M.G. 1995. Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2. Genes & Dev. 9:3122-3135.
35. Sim, F., Zhao, C., Li, W., Lakatos, A., and Franklin, R. 2002. Expression of the POU-domain transcription factors SCIP/ Oct-6 and Brn-2 is associated with Schwann cell but not oligodendrocyte remyelination of the CNS. Mol. Cell. Neurosci. 20: 669.
36. Soriano, P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21: 70-71.
37. Sugitani, Y., Nakai, S., Minowa, O., Nishi, M., Jishage, K., Kawano, H., Mori, K., Ogawa, M., and Noda, T. 2002. Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes & Dev. 16: 1760-1765.
38. Topilko, P. and Meijer, D. 2001. Transcription factors that control Schwann cell development and myelination. In Glial cell development (eds. K.R. Jessen and W.D. Richardson), pp. 223-244. Oxford University Press, Oxford.
39. Topilko, P., Schneider-Maunoury, S., Levi, G., Baron-Van Evercooren, A., Chennoufi, A.B., Seitanidou, T., Babinet, C., and Charnay, P. 1994. Krox-20 controls myelination in the peripheral nervous system. Nature 371: 796-799.
40. Waragai, M., Lammers, C.H., Takeuchi, S., Imafuku, I., Udagawa, Y., Kanazawa, I., Kawabata, M., Mouradian, M.M., and Okazawa, H. 1999. PQBP-1, a novel polyglutamine tract-binding protein, inhibits transcription activation by Brn-2 and affects cell survival. Hum. Mol. Genet. 8: 977-987.
41. Webster, H.d. 1993. Development of peripheral nerve fibers. In Peripheral neuropathy (eds. P.J. Dyck, P.K. Thomas, J.W. Griffin, P.A. Low, and J.F. Poduslo), pp. 243-266. W.B. Saunders, Philadelphia.
42. Wu, R., Jurek, M., Sundarababu, S., and Weinstein, D.E. 2001. The POU gene Brn-5 is induced by neuregulin and is restricted to myelinating Schwann cells. Mol. Cell. Neurosci. 17: 683-695.