Modulation of acid-sensing ion channel 1a by intracellular pH and its role in ischemic stroke

Journal of Biological Chemistry

Volumn 291, Issue 35, 2016, Pages 18370-18383

  Li, Ming Hua ^a   Leng, Tian Dong ^b   Feng, Xue Chao ^c   Yang, Tao ^b   Simon, Roger P ^b   Xiong, Zhi Gang ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b MOREHOUSE SCHOOL OF MEDICINE   (United States)

^c NORTHEAST NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIFICATION; ACTIVATION ANALYSIS; APPLICATION SPECIFIC INTEGRATED CIRCUITS; CHEMICAL ACTIVATION; ELECTROPHYSIOLOGY; MODULATION; MOLECULAR OXYGEN;

ACID-SENSING ION CHANNELS; BIOLOGICAL APPROACH; EXTRACELLULAR PH; IN-VITRO MODELS; INTRACELLULAR PH; ISCHEMIC STROKES; OXYGEN GLUCOSE DEPRIVATION; THERAPEUTIC STRATEGY;

ENZYME ACTIVITY;

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1A; LACTATE DEHYDROGENASE; UNCLASSIFIED DRUG; ACCN1 PROTEIN, MOUSE; ACCN2 PROTEIN, MOUSE; ACCN3 PROTEIN, MOUSE; PROPIONIC ACID DERIVATIVE;

ACIDIFICATION; ADULT; ALKALINIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCHEMISTRY; BRAIN ISCHEMIA; CHO CELL LINE; CONTROLLED STUDY; DESENSITIZATION; ELECTROPHYSIOLOGY; ENZYME RELEASE; IN VITRO STUDY; IN VIVO STUDY; LEARNING; MALE; MOUSE; NERVE CELL PLASTICITY; NEUROMODULATION; NONHUMAN; OXIDATION; PATHOGENESIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS; THERMOSTABILITY; ANIMAL; CEREBROVASCULAR ACCIDENT; DISEASE MODEL; METABOLISM; PATHOPHYSIOLOGY; PH;

ACID SENSING ION CHANNELS; ANIMALS; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; HYDROGEN-ION CONCENTRATION; MICE; PROPIONATES; STROKE;

EID: 84984689022     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.713636     Document Type: Article

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