Positioning of extracellular loop 1 affects pore gating of the cystic fibrosis transmembrane conductance regulator

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 310, Issue 5, 2016, Pages L403-L414

  Infield, Daniel T ^a,b   Cui, Guiying ^a   Kuang, Christopher ^a   McCarty, Nael A ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

ATP binding cassette transporter; Chloride channel; Cysteine mediated cross linking; Cystic fibrosis transmembrane conductance regulator; Structure function

Indexed keywords

CELL PROTEIN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EXTRACELLULAR LOOP 1; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; CHLORIDE CHANNEL; CYSTEINE;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DISULFIDE BOND; EPITHELIUM CELL; HUMAN; HUMAN CELL; INSIDE OUT PATCH CLAMP; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN FUNCTION; ROOM TEMPERATURE; SIGNAL TRANSDUCTION; CELL CULTURE; DRUG EFFECTS; MEMBRANE POTENTIAL; METABOLISM; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; PROCEDURES; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; CELLS, CULTURED; CHLORIDE CHANNELS; CYSTEINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84984633504     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00259.2015     Document Type: Article

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