Disease-associated Mutations in the Extracytoplasmic Loops of Cystic Fibrosis Transmembrane Conductance Regulator Do Not Impede Biosynthetic Processing but Impair Chloride Channel Stability

Journal of Biological Chemistry

Volumn 276, Issue 18, 2001, Pages 14848-14854

  Hämmerle, Marcus M ^b   Aleksandrov, Andrei A ^b   Riordan, John R ^a  

^a MAYO CLINIC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; BIOSYNTHESIS; CELLS; PATIENT MONITORING; POLYPEPTIDES; PROTEINS;

CYTOPLASMIC LOOPS;

DISEASES;

CHLORIDE CHANNEL; TRANSMEMBRANE CONDUCTANCE REGULATOR; PRIMER DNA;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL STRAIN BHK; CYSTIC FIBROSIS; ENDOPLASMIC RETICULUM; HUMAN; MISSENSE MUTATION; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; STRUCTURE ACTIVITY RELATION; ANIMAL; BIOSYNTHESIS; CELL LINE; CHANNEL GATING; CYTOPLASM; GENETICS; HAMSTER; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

ANIMALIA; CRICETINAE; MAMMALIA;

ANIMALS; BASE SEQUENCE; CELL LINE; CHLORIDE CHANNELS; CRICETINAE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOPLASM; DNA PRIMERS; ION CHANNEL GATING; MUTATION, MISSENSE;

EID: 0035805490     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011017200     Document Type: Article

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