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Volumn 116, Issue 1, 2016, Pages 159-170

Neuronal hyperexcitability in the ventral posterior thalamus of neuropathic rats: Modality selective effects of pregabalin

Author keywords

Nociceptive specific; Spinal nerve ligation; Ventral posterolateral thalamus; Vivo electrophysiology; Wide dynamic range

Indexed keywords

PREGABALIN; ANALGESIC AGENT;

EID: 84984621320     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00237.2016     Document Type: Article
Times cited : (39)

References (71)
  • 3
    • 65549132753 scopus 로고    scopus 로고
    • Sensitization of lamina I spinoparabrachial neurons parallels heat hyperalgesia in the chronic constriction injury model of neuropathic pain
    • Andrew D. Sensitization of lamina I spinoparabrachial neurons parallels heat hyperalgesia in the chronic constriction injury model of neuropathic pain. J Physiol 587:2005-2017, 2009.
    • (2009) J Physiol , vol.587 , pp. 2005-2017
    • Andrew, D.1
  • 4
    • 0028046102 scopus 로고
    • Squirrel monkey lateral thalamus. I. Somatic nociresponsive neurons and their relation to spinothalamic terminals
    • Apkarian AV, Shi T. Squirrel monkey lateral thalamus. I. Somatic nociresponsive neurons and their relation to spinothalamic terminals. J Neurosci 14:6779-6795, 1994.
    • (1994) J Neurosci , vol.14 , pp. 6779-6795
    • Apkarian, A.V.1    Shi, T.2
  • 5
    • 0031787829 scopus 로고    scopus 로고
    • Effects of gabapentin on the different components of peripheral and central neuropathic pain syndromes: A pilot study
    • Attal N, Brasseur L, Parker F, Chauvin M, Bouhassira D. Effects of gabapentin on the different components of peripheral and central neuropathic pain syndromes: a pilot study. Eur Neurol 40:191-200, 1998.
    • (1998) Eur Neurol , vol.40 , pp. 191-200
    • Attal, N.1    Brasseur, L.2    Parker, F.3    Chauvin, M.4    Bouhassira, D.5
  • 6
    • 79959523287 scopus 로고    scopus 로고
    • Pregabalin suppresses spinal neuronal hyperexcitability and visceral hypersensitivity in the absence of peripheral pathophysiology
    • Bannister K, Sikandar S, Bauer CS, Dolphin AC, Porreca F, Dickenson AH. Pregabalin suppresses spinal neuronal hyperexcitability and visceral hypersensitivity in the absence of peripheral pathophysiology. Anesthesiology 115:144-152, 2011.
    • (2011) Anesthesiology , vol.115 , pp. 144-152
    • Bannister, K.1    Sikandar, S.2    Bauer, C.S.3    Dolphin, A.C.4    Porreca, F.5    Dickenson, A.H.6
  • 7
    • 84867609839 scopus 로고    scopus 로고
    • Subgrouping of patients with neuropathic pain according to pain-related sensory abnormalities: A first step to a stratified treatment approach
    • Baron R, Forster M, Binder A. Subgrouping of patients with neuropathic pain according to pain-related sensory abnormalities: a first step to a stratified treatment approach. Lancet Neurol 11:999-1005, 2012.
    • (2012) Lancet Neurol , vol.11 , pp. 999-1005
    • Baron, R.1    Forster, M.2    Binder, A.3
  • 9
    • 54249121635 scopus 로고    scopus 로고
    • Descending facilitation from the brainstem determines behavioural and neuronal hypersensitivity following nerve injury and efficacy of pregabalin
    • Bee LA, Dickenson AH. Descending facilitation from the brainstem determines behavioural and neuronal hypersensitivity following nerve injury and efficacy of pregabalin. Pain 140:209-223, 2008.
    • (2008) Pain , vol.140 , pp. 209-223
    • Bee, L.A.1    Dickenson, A.H.2
  • 10
    • 0032520875 scopus 로고    scopus 로고
    • Electrophysiological characterization of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5-L6
    • Chapman V, Suzuki R, Dickenson AH. Electrophysiological characterization of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5-L6. J Physiol 507:881-894, 1998.
    • (1998) J Physiol , vol.507 , pp. 881-894
    • Chapman, V.1    Suzuki, R.2    Dickenson, A.H.3
  • 11
    • 0022482931 scopus 로고
    • Response characteristics of neurons in the ventral posterior lateral nucleus of the monkey thalamus
    • Chung JM, Lee KH, Surmeier DJ, Sorkin LS, Kim J, Willis WD. Response characteristics of neurons in the ventral posterior lateral nucleus of the monkey thalamus. J Neurophysiol 56:370-390, 1986.
    • (1986) J Neurophysiol , vol.56 , pp. 370-390
    • Chung, J.M.1    Lee, K.H.2    Surmeier, D.J.3    Sorkin, L.S.4    Kim, J.5    Willis, W.D.6
  • 12
    • 0027217539 scopus 로고
    • The roles of spatial recruitment and discharge frequency in spinal cord coding of pain: A combined electrophysiological and imaging investigation
    • Coghill RC, Mayer DJ, Price DD. The roles of spatial recruitment and discharge frequency in spinal cord coding of pain: a combined electrophysiological and imaging investigation. Pain 53:295-309, 1993.
    • (1993) Pain , vol.53 , pp. 295-309
    • Coghill, R.C.1    Mayer, D.J.2    Price, D.D.3
  • 13
    • 0027997304 scopus 로고
    • The thermal grill illusion: Unmasking the burn of cold pain
    • Craig A, Bushnell M. The thermal grill illusion: unmasking the burn of cold pain. Science 265:252-255, 1994.
    • (1994) Science , vol.265 , pp. 252-255
    • Craig, A.1    Bushnell, M.2
  • 15
    • 0036304276 scopus 로고    scopus 로고
    • Gabapentin suppresses cutaneous hyperalgesia following heat-capsaicin sensitization
    • Dirks J, Petersen KL, Rowbotham MC, Dahl JB. Gabapentin suppresses cutaneous hyperalgesia following heat-capsaicin sensitization. Anesthesiology 97:102-107, 2002.
    • (2002) Anesthesiology , vol.97 , pp. 102-107
    • Dirks, J.1    Petersen, K.L.2    Rowbotham, M.C.3    Dahl, J.B.4
  • 16
    • 11444252737 scopus 로고    scopus 로고
    • Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain
    • Donovan-Rodriguez T, Dickenson AH, Urch CE. Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain. Anesthesiology 102:132-140, 2005.
    • (2005) Anesthesiology , vol.102 , pp. 132-140
    • Donovan-Rodriguez, T.1    Dickenson, A.H.2    Urch, C.E.3
  • 17
    • 0024321359 scopus 로고
    • The correlation of monkey medullary dorsal horn neuronal activity and the perceived intensity of noxious heat stimuli
    • Dubner R, Kenshalo DR Jr, Maixner W, Bushnell MC, Oliveras JL. The correlation of monkey medullary dorsal horn neuronal activity and the perceived intensity of noxious heat stimuli. J Neurophysiol 62:450-457, 1989.
    • (1989) J Neurophysiol , vol.62 , pp. 450-457
    • Dubner, R.1    Kenshalo Jr, D.R.2    Maixner, W.3    Bushnell, M.C.4    Oliveras, J.L.5
  • 18
    • 33751232667 scopus 로고    scopus 로고
    • Identification of the α2-δ-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin
    • Field MJ, Cox PJ, Stott E, Melrose H, Offord J, Su TZ, Bramwell S, Corradini L, England S, Winks J. Identification of the α2-δ-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin. Proc Natl Acad Sci USA 103:17537-17542, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17537-17542
    • Field, M.J.1    Cox, P.J.2    Stott, E.3    Melrose, H.4    Offord, J.5    Su, T.Z.6    Bramwell, S.7    Corradini, L.8    England, S.9    Winks, J.10
  • 19
    • 0030796031 scopus 로고    scopus 로고
    • Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents
    • Field MJ, Oles RJ, Lewis AS, McCleary S, Hughes J, Singh L. Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents. Br J Pharmacol 121:1513-1522, 1997.
    • (1997) Br J Pharmacol , vol.121 , pp. 1513-1522
    • Field, M.J.1    Oles, R.J.2    Lewis, A.S.3    McCleary, S.4    Hughes, J.5    Singh, L.6
  • 21
    • 64149089630 scopus 로고    scopus 로고
    • Thalamic neuron hyperexcitability and enlarged receptive fields in the STZ model of diabetic pain
    • Fischer TZ, Tan AM, Waxman SG. Thalamic neuron hyperexcitability and enlarged receptive fields in the STZ model of diabetic pain. Brain Res 1268:154-161, 2009.
    • (2009) Brain Res , vol.1268 , pp. 154-161
    • Fischer, T.Z.1    Tan, A.M.2    Waxman, S.G.3
  • 22
    • 84892701578 scopus 로고    scopus 로고
    • Sensory profiles of patients with neuropathic pain based on the neuropathic pain symptoms and signs
    • Freeman R, Baron R, Bouhassira D, Cabrera J, Emir B. Sensory profiles of patients with neuropathic pain based on the neuropathic pain symptoms and signs. Pain 155:367-376, 2014.
    • (2014) Pain , vol.155 , pp. 367-376
    • Freeman, R.1    Baron, R.2    Bouhassira, D.3    Cabrera, J.4    Emir, B.5
  • 23
    • 0020044719 scopus 로고
    • Somatic responses of ventrobasal thalamic neurones in polyarthritic rats
    • Gautron M, Guilbaud G. Somatic responses of ventrobasal thalamic neurones in polyarthritic rats. Brain Res 237:459-471, 1982.
    • (1982) Brain Res , vol.237 , pp. 459-471
    • Gautron, M.1    Guilbaud, G.2
  • 24
    • 84868558560 scopus 로고    scopus 로고
    • Asymmetric time-dependent activation of right central amygdala neurones in rats with peripheral neuropathy and pregabalin modulation
    • Gonçalves L, Dickenson AH. Asymmetric time-dependent activation of right central amygdala neurones in rats with peripheral neuropathy and pregabalin modulation. Eur J Neurosci 36:3204-3213, 2012.
    • (2012) Eur J Neurosci , vol.36 , pp. 3204-3213
    • Gonçalves, L.1    Dickenson, A.H.2
  • 25
    • 2442426567 scopus 로고    scopus 로고
    • Allodynia in patients with post-stroke central pain (CPSP) studied by statistical quantitative sensory testing within individuals
    • Greenspan JD, Ohara S, Sarlani E, Lenz FA. Allodynia in patients with post-stroke central pain (CPSP) studied by statistical quantitative sensory testing within individuals. Pain 109:357-366, 2004.
    • (2004) Pain , vol.109 , pp. 357-366
    • Greenspan, J.D.1    Ohara, S.2    Sarlani, E.3    Lenz, F.A.4
  • 26
    • 0025242773 scopus 로고
    • Neuronal responsiveness in the ventrobasal thalamic complex of rats with an experimental peripheral mononeuropathy
    • Guilbaud G, Benoist JM, Jazat F, Gautron M. Neuronal responsiveness in the ventrobasal thalamic complex of rats with an experimental peripheral mononeuropathy. J Neurophysiol 64:1537-1554, 1990.
    • (1990) J Neurophysiol , vol.64 , pp. 1537-1554
    • Guilbaud, G.1    Benoist, J.M.2    Jazat, F.3    Gautron, M.4
  • 27
    • 0018886199 scopus 로고
    • Neurones responding to noxious stimulation in VB complex and caudal adjacent regions in the thalamus of the rat
    • Guilbaud G, Peschanski M, Gautron M, Binder D. Neurones responding to noxious stimulation in VB complex and caudal adjacent regions in the thalamus of the rat. Pain 8:303-318, 1980.
    • (1980) Pain , vol.8 , pp. 303-318
    • Guilbaud, G.1    Peschanski, M.2    Gautron, M.3    Binder, D.4
  • 28
    • 26044434843 scopus 로고    scopus 로고
    • Changes in electrophysiological properties and sodium channel Nav1.3 expression in thalamic neurons after spinal cord injury
    • Hains BC, Saab CY, Waxman SG. Changes in electrophysiological properties and sodium channel Nav1.3 expression in thalamic neurons after spinal cord injury. Brain 128:2359-2371, 2005.
    • (2005) Brain , vol.128 , pp. 2359-2371
    • Hains, B.C.1    Saab, C.Y.2    Waxman, S.G.3
  • 30
    • 84861612018 scopus 로고    scopus 로고
    • Negative reinforcement reveals non-evoked ongoing pain in mice with tissue or nerve injury
    • He Y, Tian X, Hu X, Porreca F, Wang ZJ. Negative reinforcement reveals non-evoked ongoing pain in mice with tissue or nerve injury. Pain 13:598-607, 2012.
    • (2012) Pain , vol.13 , pp. 598-607
    • He, Y.1    Tian, X.2    Hu, X.3    Porreca, F.4    Wang, Z.J.5
  • 32
    • 0018859593 scopus 로고
    • Responses of neurons in primate ventral posterior lateral nucleus to noxious stimuli
    • Kenshalo DR Jr, Giesler GJ Jr, Leonard RB, Willis WD. Responses of neurons in primate ventral posterior lateral nucleus to noxious stimuli. J Neurophysiol 43:1594-1614, 1980.
    • (1980) J Neurophysiol , vol.43 , pp. 1594-1614
    • Kenshalo Jr, D.R.1    Giesler Jr, G.J.2    Leonard, R.B.3    Willis, W.D.4
  • 33
    • 34247882866 scopus 로고    scopus 로고
    • Lesions limited to the human thalamic principal somatosensory nucleus (ventral caudal) are associated with loss of cold sensations and central pain
    • Kim JH, Greenspan JD, Coghill RC, Ohara S, Lenz FA. Lesions limited to the human thalamic principal somatosensory nucleus (ventral caudal) are associated with loss of cold sensations and central pain. J Neurosci 27:4995-5004, 2007.
    • (2007) J Neurosci , vol.27 , pp. 4995-5004
    • Kim, J.H.1    Greenspan, J.D.2    Coghill, R.C.3    Ohara, S.4    Lenz, F.A.5
  • 34
    • 84894586034 scopus 로고    scopus 로고
    • Enhancing K-Cl co-transport restores normal spinothalamic sensory coding in a neuropathic pain model
    • Lavertu G, Cote SL, De Koninck Y. Enhancing K-Cl co-transport restores normal spinothalamic sensory coding in a neuropathic pain model. Brain 137:724-738, 2014.
    • (2014) Brain , vol.137 , pp. 724-738
    • Lavertu, G.1    Cote, S.L.2    De Koninck, Y.3
  • 36
    • 77950625746 scopus 로고    scopus 로고
    • Spinal processing of noxious and innocuous cold information: Differential modulation by the periaqueductal gray
    • Leith JL, Koutsikou S, Lumb BM, Apps R. Spinal processing of noxious and innocuous cold information: differential modulation by the periaqueductal gray. J Neurosci 30:4933-4942, 2010.
    • (2010) J Neurosci , vol.30 , pp. 4933-4942
    • Leith, J.L.1    Koutsikou, S.2    Lumb, B.M.3    Apps, R.4
  • 39
    • 0022508683 scopus 로고
    • Wide-dynamic-range dorsal horn neurons participate in the encoding process by which monkeys perceive the intensity of noxious heat stimuli
    • Maixner W, Dubner R, Bushnell MC, Kenshalo DR Jr, Oliveras JL. Wide-dynamic-range dorsal horn neurons participate in the encoding process by which monkeys perceive the intensity of noxious heat stimuli. Brain Res 374:385-388, 1986.
    • (1986) Brain Res , vol.374 , pp. 385-388
    • Maixner, W.1    Dubner, R.2    Bushnell, M.C.3    Kenshalo Jr, D.R.4    Oliveras, J.L.5
  • 40
    • 84876090616 scopus 로고    scopus 로고
    • Peptidergic CGRPα primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold
    • McCoy ES, Taylor-Blake B, Street SE, Pribisko AL, Zheng J, Zylka MJ. Peptidergic CGRPα primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold. Neuron 78:138-151, 2013.
    • (2013) Neuron , vol.78 , pp. 138-151
    • McCoy, E.S.1    Taylor-Blake, B.2    Street, S.E.3    Pribisko, A.L.4    Zheng, J.5    Zylka, M.J.6
  • 41
    • 0033961211 scopus 로고    scopus 로고
    • Dorsal column-thalamic pathway is involved in thalamic hyperexcitability following peripheral nerve injury: A lesion study in rats with experimental mononeuropathy
    • Miki K, Iwata K, Tsuboi Y, Morimoto T, Kondo E, Dai Y, Ren K, Noguchi K. Dorsal column-thalamic pathway is involved in thalamic hyperexcitability following peripheral nerve injury: a lesion study in rats with experimental mononeuropathy. Pain 85:263-271, 2000.
    • (2000) Pain , vol.85 , pp. 263-271
    • Miki, K.1    Iwata, K.2    Tsuboi, Y.3    Morimoto, T.4    Kondo, E.5    Dai, Y.6    Ren, K.7    Noguchi, K.8
  • 42
    • 42549170053 scopus 로고    scopus 로고
    • Glycine inhibitory dysfunction turns touch into pain through PKCγ interneurons
    • Miraucourt LS, Dallel R, Voisin DL. Glycine inhibitory dysfunction turns touch into pain through PKCγ interneurons. PLoS One 2: e1116, 2007.
    • (2007) PLoS One , vol.2
    • Miraucourt, L.S.1    Dallel, R.2    Voisin, D.L.3
  • 43
    • 33748139371 scopus 로고    scopus 로고
    • Corticofugal output from the primary somatosensory cortex selectively modulates innocuous and noxious inputs in the rat spinothalamic system
    • Monconduit L, Lopez-Avila A, Molat JL, Chalus M, Villanueva L. Corticofugal output from the primary somatosensory cortex selectively modulates innocuous and noxious inputs in the rat spinothalamic system. J Neurosci 26:8441-8450, 2006.
    • (2006) J Neurosci , vol.26 , pp. 8441-8450
    • Monconduit, L.1    Lopez-Avila, A.2    Molat, J.L.3    Chalus, M.4    Villanueva, L.5
  • 44
    • 0036703985 scopus 로고    scopus 로고
    • Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord
    • Moore KA, Kohno T, Karchewski LA, Scholz J, Baba H, Woolf CJ. Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord. J Neurosci 22:6724-6731, 2002.
    • (2002) J Neurosci , vol.22 , pp. 6724-6731
    • Moore, K.A.1    Kohno, T.2    Karchewski, L.A.3    Scholz, J.4    Baba, H.5    Woolf, C.J.6
  • 47
    • 0028209055 scopus 로고
    • The triple cold syndrome: Cold hyperalgesia, cold hypoaesthesia and cold skin in peripheral nerve disease
    • Ochoa JL, Yarnitsky D. The triple cold syndrome: cold hyperalgesia, cold hypoaesthesia and cold skin in peripheral nerve disease. Brain 117:185-197, 1994.
    • (1994) Brain , vol.117 , pp. 185-197
    • Ochoa, J.L.1    Yarnitsky, D.2
  • 48
    • 0842349520 scopus 로고    scopus 로고
    • Microstimulation in the region of the human thalamic principal somatic sensory nucleus evokes sensations like those of mechanical stimulation and movement
    • Ohara S, Weiss N, Lenz FA. Microstimulation in the region of the human thalamic principal somatic sensory nucleus evokes sensations like those of mechanical stimulation and movement. J Neurophysiol 91:736-745, 2004.
    • (2004) J Neurophysiol , vol.91 , pp. 736-745
    • Ohara, S.1    Weiss, N.2    Lenz, F.A.3
  • 49
    • 84940575048 scopus 로고    scopus 로고
    • Human psychophysics and rodent spinal neurones exhibit peripheral and central mechanisms of inflammatory pain in the UVB and UVB heat rekindling models
    • O’Neill J, Sikandar S, McMahon SB, Dickenson AH. Human psychophysics and rodent spinal neurones exhibit peripheral and central mechanisms of inflammatory pain in the UVB and UVB heat rekindling models. J Physiol 593:4029-4042, 2015.
    • (2015) J Physiol , vol.593 , pp. 4029-4042
    • O’Neill, J.1    Sikandar, S.2    McMahon, S.B.3    Dickenson, A.H.4
  • 50
    • 0026751792 scopus 로고
    • Responses of spinothalamic tract cells to mechanical and thermal stimulation of skin in rats with experimental peripheral neuropathy
    • Palecek J, Paleckova V, Dougherty PM, Carlton SM, Willis WD. Responses of spinothalamic tract cells to mechanical and thermal stimulation of skin in rats with experimental peripheral neuropathy. J Neurophysiol 67:1562-1573, 1992.
    • (1992) J Neurophysiol , vol.67 , pp. 1562-1573
    • Palecek, J.1    Paleckova, V.2    Dougherty, P.M.3    Carlton, S.M.4    Willis, W.D.5
  • 52
    • 84954315708 scopus 로고    scopus 로고
    • Ionic mechanisms of spinal neuronal cold hypersensitivity in ciguatera
    • Patel R, Brice NL, Lewis RJ, Dickenson AH. Ionic mechanisms of spinal neuronal cold hypersensitivity in ciguatera. Eur J Neurosci 42:3004-3011, 2015.
    • (2015) Eur J Neurosci , vol.42 , pp. 3004-3011
    • Patel, R.1    Brice, N.L.2    Lewis, R.J.3    Dickenson, A.H.4
  • 53
    • 84995532799 scopus 로고    scopus 로고
    • Mechanisms of the gabapentinoids and α2δ-1 calcium channel subunit in neuropathic pain
    • Patel R, Dickenson AH. Mechanisms of the gabapentinoids and α2δ-1 calcium channel subunit in neuropathic pain. Pharmacol Res Perspect 4:e00205, 2016.
    • (2016) Pharmacol Res Perspect , vol.4 , pp. e00205
    • Patel, R.1    Dickenson, A.H.2
  • 54
    • 84908082837 scopus 로고    scopus 로고
    • Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: A comparison with topical menthol
    • Patel R, Gonçalves L, Leveridge M, Mack SR, Hendrick A, Brice NL, Dickenson AH. Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: a comparison with topical menthol. Pain 155: 2097-2107, 2014a.
    • (2014) Pain , vol.155 , pp. 2097-2107
    • Patel, R.1    Gonçalves, L.2    Leveridge, M.3    Mack, S.R.4    Hendrick, A.5    Brice, N.L.6    Dickenson, A.H.7
  • 56
    • 40049085287 scopus 로고    scopus 로고
    • Spread of excitation across modality borders in spinal dorsal horn of neuropathic rats
    • Schoffnegger D, Ruscheweyh R, Sandkuhler J. Spread of excitation across modality borders in spinal dorsal horn of neuropathic rats. Pain 135:300-310, 2008.
    • (2008) Pain , vol.135 , pp. 300-310
    • Schoffnegger, D.1    Ruscheweyh, R.2    Sandkuhler, J.3
  • 57
    • 0030657504 scopus 로고    scopus 로고
    • Altered receptive fields and sensory modalities of rat VPL thalamic neurons during spinal strychnine-induced allodynia
    • Sherman SE, Luo L, Dostrovsky JO. Altered receptive fields and sensory modalities of rat VPL thalamic neurons during spinal strychnine-induced allodynia. J Neurophysiol 78:2296-2308, 1997.
    • (1997) J Neurophysiol , vol.78 , pp. 2296-2308
    • Sherman, S.E.1    Luo, L.2    Dostrovsky, J.O.3
  • 58
    • 84879787044 scopus 로고    scopus 로고
    • Neural coding of nociceptive stimuli-from rat spinal neurones to human perception
    • Sikandar S, Ronga I, Iannetti GD, Dickenson AH. Neural coding of nociceptive stimuli-from rat spinal neurones to human perception. Pain 154:1263-1273, 2013.
    • (2013) Pain , vol.154 , pp. 1263-1273
    • Sikandar, S.1    Ronga, I.2    Iannetti, G.D.3    Dickenson, A.H.4
  • 61
    • 32644443819 scopus 로고    scopus 로고
    • Differential pharmacological modulation of the spontaneous stimulus-independent activity in the rat spinal cord following peripheral nerve injury
    • Suzuki R, Dickenson AH. Differential pharmacological modulation of the spontaneous stimulus-independent activity in the rat spinal cord following peripheral nerve injury. Exp Neurol 198:72-80, 2006.
    • (2006) Exp Neurol , vol.198 , pp. 72-80
    • Suzuki, R.1    Dickenson, A.H.2
  • 62
    • 0037156486 scopus 로고    scopus 로고
    • Nerve injury-induced changes in opioid modulation of wide dynamic range dorsal column nuclei neurones
    • Suzuki R, Dickenson AH. Nerve injury-induced changes in opioid modulation of wide dynamic range dorsal column nuclei neurones. Neuroscience 111:215-228, 2002.
    • (2002) Neuroscience , vol.111 , pp. 215-228
    • Suzuki, R.1    Dickenson, A.H.2
  • 63
    • 0034125842 scopus 로고    scopus 로고
    • Enlargement of the receptive field size to low intensity mechanical stimulation in the rat spinal nerve ligation model of neuropathy
    • Suzuki R, Kontinen VK, Matthews E, Williams E, Dickenson AH. Enlargement of the receptive field size to low intensity mechanical stimulation in the rat spinal nerve ligation model of neuropathy. Exp Neurol 163:408-413, 2000.
    • (2000) Exp Neurol , vol.163 , pp. 408-413
    • Suzuki, R.1    Kontinen, V.K.2    Matthews, E.3    Williams, E.4    Dickenson, A.H.5
  • 64
    • 25644445926 scopus 로고    scopus 로고
    • Spinal-supraspinal serotonergic circuits regulating neuropathic pain and its treatment with gabapentin
    • Suzuki R, Rahman W, Rygh LJ, Webber M, Hunt SP, Dickenson AH. Spinal-supraspinal serotonergic circuits regulating neuropathic pain and its treatment with gabapentin. Pain 117:292-303, 2005.
    • (2005) Pain , vol.117 , pp. 292-303
    • Suzuki, R.1    Rahman, W.2    Rygh, L.J.3    Webber, M.4    Hunt, S.P.5    Dickenson, A.H.6
  • 65
    • 0034034375 scopus 로고    scopus 로고
    • Changes in neuronal activities in the two ventral posterior medial thalamic nuclei in an experimental model of trigeminal pain in the rat by constriction of one infraorbital nerve
    • Vos BP, Benoist JM, Gautron M, Guilbaud G. Changes in neuronal activities in the two ventral posterior medial thalamic nuclei in an experimental model of trigeminal pain in the rat by constriction of one infraorbital nerve. Somatosens Mot Res 17:109-122, 2000.
    • (2000) Somatosens Mot Res , vol.17 , pp. 109-122
    • Vos, B.P.1    Benoist, J.M.2    Gautron, M.3    Guilbaud, G.4
  • 67
    • 0034619525 scopus 로고    scopus 로고
    • Functional plasticity in primate somatosensory thalamus following chronic lesion of the ventral lateral spinal cord
    • Weng HR, Lee JI, Lenz FA, Schwartz A, Vierck C, Rowland L, Dougherty PM. Functional plasticity in primate somatosensory thalamus following chronic lesion of the ventral lateral spinal cord. Neuroscience 101:393-401, 2000.
    • (2000) Neuroscience , vol.101 , pp. 393-401
    • Weng, H.R.1    Lee, J.I.2    Lenz, F.A.3    Schwartz, A.4    Vierck, C.5    Rowland, L.6    Dougherty, P.M.7
  • 68
    • 84874608734 scopus 로고    scopus 로고
    • Pathological activity in mediodorsal thalamus of rats with spinal cord injury pain
    • Whitt JL, Masri R, Pulimood NS, Keller A. Pathological activity in mediodorsal thalamus of rats with spinal cord injury pain. J Neurosci 33:3915-3926, 2013.
    • (2013) J Neurosci , vol.33 , pp. 3915-3926
    • Whitt, J.L.1    Masri, R.2    Pulimood, N.S.3    Keller, A.4
  • 69
    • 0035057019 scopus 로고    scopus 로고
    • Projections from the marginal zone and deep dorsal horn to the ventrobasal nuclei of the primate thalamus
    • Willis WD Jr, Zhang X, Honda CN, Giesler GJ Jr. Projections from the marginal zone and deep dorsal horn to the ventrobasal nuclei of the primate thalamus. Pain 92:267-276, 2001.
    • (2001) Pain , vol.92 , pp. 267-276
    • Willis Jr, W.D.1    Zhang, X.2    Honda, C.N.3    Giesler Jr, G.J.4
  • 70
    • 0024159951 scopus 로고
    • Nociceptive body representation in nucleus ventralis posterolateralis of cat thalamus
    • Yokota T, Asato F, Koyama N, Masuda T, Taguchi H. Nociceptive body representation in nucleus ventralis posterolateralis of cat thalamus. J Neurophysiol 60:1714-1727, 1988.
    • (1988) J Neurophysiol , vol.60 , pp. 1714-1727
    • Yokota, T.1    Asato, F.2    Koyama, N.3    Masuda, T.4    Taguchi, H.5
  • 71
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16:109-110, 1983.
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.