메뉴 건너뛰기




Volumn 310, Issue 7, 2016, Pages H873-H890

Myocyte repolarization modulates myocardial function in aging dogs

Author keywords

Aging; Contractile reserve; Myocardium

Indexed keywords

ACTION POTENTIAL; ADULT; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEAGLE; CARDIAC MUSCLE; CELL POPULATION; CELL VOLUME; FEMALE; HEART FUNCTION; HEART HEMODYNAMICS; HEART REPOLARIZATION; HEART VENTRICLE FUNCTION; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE PERFORMANCE; INOTROPISM; MALE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; SENESCENCE; ANIMAL; CARDIAC MUSCLE CELL; DOG; HEMODYNAMICS; PHYSIOLOGY;

EID: 84983775755     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00682.2015     Document Type: Article
Times cited : (20)

References (56)
  • 3
    • 84921032106 scopus 로고    scopus 로고
    • Cardiac late Na (+) current: Proarrhythmic effects, roles in long QT syndromes, and pathological relationship to CaMKII and oxidative stress
    • Belardinelli L, Giles WR, Rajamani S, Karagueuzian HS, Shryock JC. Cardiac late Na (+) current: proarrhythmic effects, roles in long QT syndromes, and pathological relationship to CaMKII and oxidative stress. Heart Rhythm 12: 440–448, 2015.
    • (2015) Heart Rhythm , vol.12 , pp. 440-448
    • Belardinelli, L.1    Giles, W.R.2    Rajamani, S.3    Karagueuzian, H.S.4    Shryock, J.C.5
  • 5
    • 79956330068 scopus 로고    scopus 로고
    • Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy
    • Boyle AJ, Shih H, Hwang J, Ye J, Lee B, Zhang Y, Kwon D, Jun K, Zheng D, Sievers R, Angeli F, Yeghiazarians Y, Lee R. Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy. Exp Gerontol 46: 549–559, 2011.
    • (2011) Exp Gerontol , vol.46 , pp. 549-559
    • Boyle, A.J.1    Shih, H.2    Hwang, J.3    Ye, J.4    Lee, B.5    Zhang, Y.6    Kwon, D.7    Jun, K.8    Zheng, D.9    Sievers, R.10    Angeli, F.11    Yeghiazarians, Y.12    Lee, R.13
  • 11
    • 0018655360 scopus 로고
    • Diminished inotropic responses but unaltered toxicity to acetylstrophanthidin in the senescent beagle
    • Guarnieri T, Spurgeon H, Forehlich JP, Weisfeldt ML, Lakatta EG. Diminished inotropic responses but unaltered toxicity to acetylstrophanthidin in the senescent beagle. Circulation 60: 1548–1554, 1979.
    • (1979) Circulation , vol.60 , pp. 1548-1554
    • Guarnieri, T.1    Spurgeon, H.2    Forehlich, J.P.3    Weisfeldt, M.L.4    Lakatta, E.G.5
  • 12
    • 33645396686 scopus 로고    scopus 로고
    • Effects of normal aging on left ventricular lusitropic, inotropic, and chronotropic responses to dobutamine
    • Hees PS, Fleg JL, Mirza ZA, Ahmed S, Siu CO, Shapiro EP. Effects of normal aging on left ventricular lusitropic, inotropic, and chronotropic responses to dobutamine. J Am Coll Cardiol 47: 1440–1447, 2006.
    • (2006) J am Coll Cardiol , vol.47 , pp. 1440-1447
    • Hees, P.S.1    Fleg, J.L.2    Mirza, Z.A.3    Ahmed, S.4    Siu, C.O.5    Shapiro, E.P.6
  • 13
    • 0036624059 scopus 로고    scopus 로고
    • Action potential prolongation in cardiac myocytes of old rats is an adaptation to sustain youthful intracellular Ca2+ regulation
    • Janczewski AM, Spurgeon HA, Lakatta EG. Action potential prolongation in cardiac myocytes of old rats is an adaptation to sustain youthful intracellular Ca2+ regulation. J Mol Cell Cardiol 34: 641–648, 2002.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 641-648
    • Janczewski, A.M.1    Spurgeon, H.A.2    Lakatta, E.G.3
  • 14
    • 35348995458 scopus 로고    scopus 로고
    • Determinants of frequency-dependent contraction and relaxation of mammalian myocardium
    • Janssen PM, Periasamy M. Determinants of frequency-dependent contraction and relaxation of mammalian myocardium. J Mol Cell Cardiol 43: 523–531, 2007.
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 523-531
    • Janssen, P.M.1    Periasamy, M.2
  • 15
    • 84862286538 scopus 로고    scopus 로고
    • Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome
    • Kranias EG, Hajjar RJ. Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome. Circ Res 110: 1646–1660, 2012.
    • (2012) Circ Res , vol.110 , pp. 1646-1660
    • Kranias, E.G.1    Hajjar, R.J.2
  • 16
    • 0036517410 scopus 로고    scopus 로고
    • Morphology of ventricular arrhythmias in the boxer as measured by 12-lead electrocardiography with pace-mapping comparison
    • Kraus MS, Moise NS, Rishniw M, Dykes N, Erb HN. Morphology of ventricular arrhythmias in the boxer as measured by 12-lead electrocardiography with pace-mapping comparison. J Vet Intern Med 16: 153–158, 2002.
    • (2002) J Vet Intern Med , vol.16 , pp. 153-158
    • Kraus, M.S.1    Moise, N.S.2    Rishniw, M.3    Dykes, N.4    Erb, H.N.5
  • 17
    • 0037469206 scopus 로고    scopus 로고
    • Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises: Part III: Cellular and molecular clues to heart and arterial aging
    • Lakatta EG. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging. Circulation 107: 490–497, 2003.
    • (2003) Circulation , vol.107 , pp. 490-497
    • Lakatta, E.G.1
  • 18
    • 0037458070 scopus 로고    scopus 로고
    • Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises: Part II: The aging heart in health: Links to heart disease
    • Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease. Circulation 107: 346–354, 2003.
    • (2003) Circulation , vol.107 , pp. 346-354
    • Lakatta, E.G.1    Levy, D.2
  • 19
    • 81855220379 scopus 로고    scopus 로고
    • How to interpret elevated cardiac troponin levels
    • Mahajan VS, Jarolim P. How to interpret elevated cardiac troponin levels. Circulation 124: 2350–2354, 2011.
    • (2011) Circulation , vol.124 , pp. 2350-2354
    • Mahajan, V.S.1    Jarolim, P.2
  • 21
    • 33847261532 scopus 로고    scopus 로고
    • Chronic heart failure slows late sodium current in human and canine ventricular myocytes: Implications for repolarization variability
    • Maltsev VA, Silverman N, Sabbah HN, Undrovinas AI. Chronic heart failure slows late sodium current in human and canine ventricular myocytes: implications for repolarization variability. Eur J Heart Fail 9: 219–227, 2007.
    • (2007) Eur J Heart Fail , vol.9 , pp. 219-227
    • Maltsev, V.A.1    Silverman, N.2    Sabbah, H.N.3    Undrovinas, A.I.4
  • 22
    • 42749091983 scopus 로고    scopus 로고
    • Late sodium current in failing heart: Friend or foe?
    • Maltsev VA, Undrovinas A. Late sodium current in failing heart: friend or foe? Progr Biophys Mol Biol 96: 421–451, 2008.
    • (2008) Progr Biophys Mol Biol , vol.96 , pp. 421-451
    • Maltsev, V.A.1    Undrovinas, A.2
  • 23
    • 84857640089 scopus 로고    scopus 로고
    • Pathophysiology of the cardiac late Na current and its potential as a drug target
    • Moreno JD, Clancy CE. Pathophysiology of the cardiac late Na current and its potential as a drug target. J Mol Cell Cardiol 52: 608–619, 2012.
    • (2012) J Mol Cell Cardiol , vol.52 , pp. 608-619
    • Moreno, J.D.1    Clancy, C.E.2
  • 26
    • 0025801813 scopus 로고
    • Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy
    • Olivetti G, Melissari M, Capasso JM, Anversa P. Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy. Circ Res 68: 1560–1568, 1991.
    • (1991) Circ Res , vol.68 , pp. 1560-1568
    • Olivetti, G.1    Melissari, M.2    Capasso, J.M.3    Anversa, P.4
  • 27
    • 0022457815 scopus 로고
    • Comparison of the inhibitory effects of mexiletine and lidocaine on the calcium current of single ventricular cells
    • Ono K, Kiyosue T, Arita M. Comparison of the inhibitory effects of mexiletine and lidocaine on the calcium current of single ventricular cells. Life Sci 39: 1465–1470, 1986.
    • (1986) Life Sci , vol.39 , pp. 1465-1470
    • Ono, K.1    Kiyosue, T.2    Arita, M.3
  • 28
    • 0035707254 scopus 로고    scopus 로고
    • Plasma nitrate accumulation during the development of pacing-induced dilated cardiac myopathy in conscious dogs is due to renal impairment
    • Osorio JC, Xu X, Vogel T, Ochoa M, Laycock S, Hintze TH. Plasma nitrate accumulation during the development of pacing-induced dilated cardiac myopathy in conscious dogs is due to renal impairment. Nitric Oxide 5: 7–17, 2001.
    • (2001) Nitric Oxide , vol.5 , pp. 7-17
    • Osorio, J.C.1    Xu, X.2    Vogel, T.3    Ochoa, M.4    Laycock, S.5    Hintze, T.H.6
  • 29
    • 0030992739 scopus 로고    scopus 로고
    • Comparative longevity of pet dogs and humans: Implications for gerontology research
    • Patronek GJ, Waters DJ, Glickman LT. Comparative longevity of pet dogs and humans: implications for gerontology research. J Gerontol A Biol Sci Med Sci 52: B171–178, 1997.
    • (1997) J Gerontol a Biol Sci Med Sci , vol.52 , pp. B171-B178
    • Patronek, G.J.1    Waters, D.J.2    Glickman, L.T.3
  • 31
    • 0037162348 scopus 로고    scopus 로고
    • Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardium
    • Pieske B, Maier LS, Piacentino V, Weisser J 3rd, Hasenfuss G, Houser S. Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardium. Circulation 106: 447–453, 2002.
    • (2002) Circulation , vol.106 , pp. 447-453
    • Pieske, B.1    Maier, L.S.2    Piacentino, V.3    Weisser, J.4    Hasenfuss, G.5    Houser, S.6
  • 32
    • 33646172938 scopus 로고    scopus 로고
    • Characterization of the myosin-based source for second-harmonic generation from muscle sarcomeres
    • Plotnikov SV, Millard AC, Campagnola PJ, Mohler WA. Characterization of the myosin-based source for second-harmonic generation from muscle sarcomeres. Biophys J 90: 693–703, 2006.
    • (2006) Biophys J , vol.90 , pp. 693-703
    • Plotnikov, S.V.1    Millard, A.C.2    Campagnola, P.J.3    Mohler, W.A.4
  • 34
    • 0029852085 scopus 로고    scopus 로고
    • QT interval change with age in an overtly healthy older population
    • Reardon M, Malik M. QT interval change with age in an overtly healthy older population. Clin Cardiol 19: 949–952, 1996.
    • (1996) Clin Cardiol , vol.19 , pp. 949-952
    • Reardon, M.1    Malik, M.2
  • 36
    • 0037386150 scopus 로고    scopus 로고
    • Patch-clamp analysis in canine cardiac Purkinje cells of a novel sodium component in the pacemaker range
    • Rota M, Vassalle M. Patch-clamp analysis in canine cardiac Purkinje cells of a novel sodium component in the pacemaker range. J Physiol 548: 147–165, 2003.
    • (2003) J Physiol , vol.548 , pp. 147-165
    • Rota, M.1    Vassalle, M.2
  • 37
    • 0026473989 scopus 로고
    • Spontaneous and inducible ventricular arrhythmias in a canine model of chronic heart failure: Relation to haemodynamics and sympathoadrenergic activation
    • Sabbah HN, Goldberg AD, Schoels W, Kono T, Webb C, Brachmann J, Goldstein S. Spontaneous and inducible ventricular arrhythmias in a canine model of chronic heart failure: relation to haemodynamics and sympathoadrenergic activation. Eur Heart J 13: 1562–1572, 1992.
    • (1992) Eur Heart J , vol.13 , pp. 1562-1572
    • Sabbah, H.N.1    Goldberg, A.D.2    Schoels, W.3    Kono, T.4    Webb, C.5    Brachmann, J.6    Goldstein, S.7
  • 38
    • 0035866930 scopus 로고    scopus 로고
    • Alterations in action potential profile enhance excitation-contraction coupling in rat cardiac myocytes
    • Sah R, Ramirez RJ, Kaprielian R, Backx PH. Alterations in action potential profile enhance excitation-contraction coupling in rat cardiac myocytes. J Physiol 533: 201–214, 2001.
    • (2001) J Physiol , vol.533 , pp. 201-214
    • Sah, R.1    Ramirez, R.J.2    Kaprielian, R.3    Backx, P.H.4
  • 39
    • 80053505247 scopus 로고    scopus 로고
    • Cardiovascular disease in the elderly
    • (9th ed.), edited by Bonow R, Mann D, Zipes D, Libby P. Philadelphia, PA: Saunders
    • Schwartz J, Zipes D. Cardiovascular disease in the elderly. In: Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine (9th ed.), edited by Bonow R, Mann D, Zipes D, Libby P. Philadelphia, PA: Saunders, 2011, p. 1727–1753.
    • (2011) Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine , pp. 1727-1753
    • Schwartz, J.1    Zipes, D.2
  • 40
    • 0030724030 scopus 로고    scopus 로고
    • Effects of sodium channel block with mexiletine to reverse action potential prolongation in in vitro models of the long term QT syndrome
    • Sicouri S, Antzelevitch D, Heilmann C, Antzelevitch C. Effects of sodium channel block with mexiletine to reverse action potential prolongation in in vitro models of the long term QT syndrome. J Cardiovasc Electrophysiol 8: 1280–1290, 1997.
    • (1997) J Cardiovasc Electrophysiol , vol.8 , pp. 1280-1290
    • Sicouri, S.1    Antzelevitch, D.2    Heilmann, C.3    Antzelevitch, C.4
  • 45
    • 21244492310 scopus 로고    scopus 로고
    • Myocardial substrate metabolism in the normal and failing heart
    • Stanley WC, Recchia FA, Lopaschuk GD. Myocardial substrate metabolism in the normal and failing heart. Physiol Rev 85: 1093–1129, 2005.
    • (2005) Physiol Rev , vol.85 , pp. 1093-1129
    • Stanley, W.C.1    Recchia, F.A.2    Lopaschuk, G.D.3
  • 46
    • 33846250329 scopus 로고    scopus 로고
    • Hyperhomocysteinemia alters cardiac substrate metabolism by impairing nitric oxide bioavailability through oxidative stress
    • Suematsu N, Ojaimi C, Kinugawa S, Wang Z, Xu X, Koller A, Recchia FA, Hintze TH. Hyperhomocysteinemia alters cardiac substrate metabolism by impairing nitric oxide bioavailability through oxidative stress. Circulation 115: 255–262, 2007.
    • (2007) Circulation , vol.115 , pp. 255-262
    • Suematsu, N.1    Ojaimi, C.2    Kinugawa, S.3    Wang, Z.4    Xu, X.5    Koller, A.6    Recchia, F.A.7    Hintze, T.H.8
  • 47
    • 84880161382 scopus 로고    scopus 로고
    • Causes and prevention of sudden cardiac death in the elderly
    • Tung P, Albert CM. Causes and prevention of sudden cardiac death in the elderly. Nat Rev Cardiol 10: 135–142, 2013.
    • (2013) Nat Rev Cardiol , vol.10 , pp. 135-142
    • Tung, P.1    Albert, C.M.2
  • 48
  • 49
    • 4444383632 scopus 로고    scopus 로고
    • Calcium overload and cardiac function
    • Vassalle M, Lin CI. Calcium overload and cardiac function. J Biomed Sci 11: 542–565, 2004.
    • (2004) J Biomed Sci , vol.11 , pp. 542-565
    • Vassalle, M.1    Lin, C.I.2
  • 51
    • 85047679398 scopus 로고
    • Age associated changes in membrane currents in rat ventricular myocytes
    • Walker KE, Lakatta EG, Houser SR. Age associated changes in membrane currents in rat ventricular myocytes. Cardiovasc Res 27: 1968–1977, 1993.
    • (1993) Cardiovasc Res , vol.27 , pp. 1968-1977
    • Walker, K.E.1    Lakatta, E.G.2    Houser, S.R.3
  • 53
    • 79955559140 scopus 로고    scopus 로고
    • Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization
    • Wu L, Ma J, Li H, Wang C, Grandi E, Zhang P, Luo A, Bers DM, Shryock JC, Belardinelli L. Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization. Circulation 123: 1713–1720, 2011.
    • (2011) Circulation , vol.123 , pp. 1713-1720
    • Wu, L.1    Ma, J.2    Li, H.3    Wang, C.4    Grandi, E.5    Zhang, P.6    Luo, A.7    Bers, D.M.8    Shryock, J.C.9    Belardinelli, L.10
  • 54
    • 50649110687 scopus 로고    scopus 로고
    • Pathophysiology and pharmacology of the cardiac “late sodium current”
    • Zaza A, Belardinelli L, Shryock JC. Pathophysiology and pharmacology of the cardiac “late sodium current”. Pharmacol Ther 119: 326–339, 2008.
    • (2008) Pharmacol Ther , vol.119 , pp. 326-339
    • Zaza, A.1    Belardinelli, L.2    Shryock, J.C.3
  • 55
    • 84873058846 scopus 로고    scopus 로고
    • The late Na+ current-origin and pathophysiological relevance
    • Zaza A, Rocchetti M. The late Na+ current-origin and pathophysiological relevance. Cardiovasc Drugs Ther 27: 61–68, 2013.
    • (2013) Cardiovasc Drugs Ther , vol.27 , pp. 61-68
    • Zaza, A.1    Rocchetti, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.