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Volumn 310, Issue 9, 2016, Pages H1176-H1183

Ac-SDKP suppresses TNF-α-induced ICAM-1 expression in endothelial cells via inhibition of iκB kinase and NF-κB activation

Author keywords

Ac SDKP; Endothelial cells; In ammation; NF B; TNF

Indexed keywords

I KAPPA B KINASE; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SERASPENIDE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; ANTIINFLAMMATORY AGENT; ICAM1 PROTEIN, HUMAN; IKBKB PROTEIN, HUMAN; OLIGOPEPTIDE;

EID: 84983751551     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00252.2015     Document Type: Article
Times cited : (22)

References (43)
  • 1
    • 0027935309 scopus 로고
    • Leukocyte-endothelial adhesion molecules
    • Carlos TM, Harlan JM. Leukocyte-endothelial adhesion molecules. Blood 84: 2068–2101, 1994.
    • (1994) Blood , vol.84 , pp. 2068-2101
    • Carlos, T.M.1    Harlan, J.M.2
  • 2
    • 33750989327 scopus 로고    scopus 로고
    • Therapeutic potential of thymosin-beta4 and its derivative N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) in cardiac healing after infarction
    • Cavasin MA. Therapeutic potential of thymosin-beta4 and its derivative N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) in cardiac healing after infarction. Am J Cardiovasc Drugs 6: 305–311, 2006.
    • (2006) Am J Cardiovasc Drugs , vol.6 , pp. 305-311
    • Cavasin, M.A.1
  • 4
    • 0033537719 scopus 로고    scopus 로고
    • Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation
    • Delhase M, Hayakawa M, Chen Y, Karin M. Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation. Science 284: 309–313, 1999.
    • (1999) Science , vol.284 , pp. 309-313
    • Delhase, M.1    Hayakawa, M.2    Chen, Y.3    Karin, M.4
  • 5
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
    • DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature 388: 548–554, 1997.
    • (1997) Nature , vol.388 , pp. 548-554
    • Didonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 6
    • 84885062062 scopus 로고    scopus 로고
    • N-acetyl-seryl-aspartyl-lysyl-proline reduces cardiac collagen cross-linking and inflammation in angiotensin II-induced hypertensive rats
    • Gonzalez GE, Rhaleb NE, Nakagawa P, Liao TD, Liu Y, Leung P, Dai X, Yang XP, Carretero OA. N-acetyl-seryl-aspartyl-lysyl-proline reduces cardiac collagen cross-linking and inflammation in angiotensin II-induced hypertensive rats. Clin Sci (Lond) 126: 85–94, 2014.
    • (2014) Clin Sci (Lond) , vol.126 , pp. 85-94
    • Gonzalez, G.E.1    Rhaleb, N.E.2    Nakagawa, P.3    Liao, T.D.4    Liu, Y.5    Leung, P.6    Dai, X.7    Yang, X.P.8    Carretero, O.A.9
  • 7
    • 0027171996 scopus 로고
    • Optimization of cell culture conditions for the evaluation of the biological activities of the tetrapeptide N-acetyl-ser-asp-lys-pro, a natural hemoregulatory factor
    • Grillon C, Lenfant M, Wdzieczak-Bakala J. Optimization of cell culture conditions for the evaluation of the biological activities of the tetrapeptide N-acetyl-ser-asp-lys-pro, a natural hemoregulatory factor. Growth Factors 9: 133–138, 1993.
    • (1993) Growth Factors , vol.9 , pp. 133-138
    • Grillon, C.1    Lenfant, M.2    Wdzieczak-Bakala, J.3
  • 8
    • 77951035820 scopus 로고    scopus 로고
    • Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway
    • Harikumar KB, Sung B, Pandey MK, Guha S, Krishnan S, Aggarwal BB. Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway. Mol Pharmacol 77: 818–827, 2010.
    • (2010) Mol Pharmacol , vol.77 , pp. 818-827
    • Harikumar, K.B.1    Sung, B.2    Pandey, M.K.3    Guha, S.4    Krishnan, S.5    Aggarwal, B.B.6
  • 9
    • 77957252647 scopus 로고    scopus 로고
    • The IKK complex, a central regulator of NF-kappaB activation
    • Israel A. The IKK complex, a central regulator of NF-kappaB activation. Cold Spring Harb Perspect Biol 2: a000158, 2010.
    • (2010) Cold Spring Harb Perspect Biol , vol.a000158 , pp. 2
    • Israel, A.1
  • 10
    • 66949136652 scopus 로고    scopus 로고
    • ICAM-1 signaling in endothelial cells
    • Lawson C, Wolf S. ICAM-1 signaling in endothelial cells. Pharmacol Rep 61: 22–32, 2009.
    • (2009) Pharmacol Rep , vol.61 , pp. 22-32
    • Lawson, C.1    Wolf, S.2
  • 11
    • 84908110008 scopus 로고    scopus 로고
    • IkappaB kinase-beta inhibitor IMD-0354 beneficially suppresses retinal vascular permeability in streptozotocin-induced diabetic mice
    • Lennikov A, Hiraoka M, Abe A, Ohno S, Fujikawa T, Itai A, Ohguro H. IkappaB kinase-beta inhibitor IMD-0354 beneficially suppresses retinal vascular permeability in streptozotocin-induced diabetic mice. Invest Ophthalmol Vis Sci 55: 6365–6373, 2014.
    • (2014) Invest Ophthalmol Vis Sci , vol.55 , pp. 6365-6373
    • Lennikov, A.1    Hiraoka, M.2    Abe, A.3    Ohno, S.4    Fujikawa, T.5    Itai, A.6    Ohguro, H.7
  • 12
    • 0034661272 scopus 로고    scopus 로고
    • Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: Additional defect in neurulation
    • Li Q, Estepa G, Memet S, Israel A, Verma IM. Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation. Genes Dev 14: 1729–1733, 2000.
    • (2000) Genes Dev , vol.14 , pp. 1729-1733
    • Li, Q.1    Estepa, G.2    Memet, S.3    Israel, A.4    Verma, I.M.5
  • 13
    • 0033532386 scopus 로고    scopus 로고
    • The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis
    • Li ZW, Chu W, Hu Y, Delhase M, Deerinck T, Ellisman M, Johnson R, Karin M. The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. J Exp Med 189: 1839–1845, 1999.
    • (1999) J Exp Med , vol.189 , pp. 1839-1845
    • Li, Z.W.1    Chu, W.2    Hu, Y.3    Delhase, M.4    Deerinck, T.5    Ellisman, M.6    Johnson, R.7    Karin, M.8
  • 17
    • 0034964508 scopus 로고    scopus 로고
    • TNF signaling in vascular endothelial cells
    • Madge LA, Pober JS. TNF signaling in vascular endothelial cells. Exp Mol Pathol 70: 317–325, 2001.
    • (2001) Exp Mol Pathol , vol.70 , pp. 317-325
    • Madge, L.A.1    Pober, J.S.2
  • 18
    • 0041853690 scopus 로고    scopus 로고
    • Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
    • Micheau O, Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114: 181–190, 2003.
    • (2003) Cell , vol.114 , pp. 181-190
    • Micheau, O.1    Tschopp, J.2
  • 19
    • 33845369349 scopus 로고    scopus 로고
    • CML-1 inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in endothelial cells through inhibition of IkBalpha kinase
    • Mo SJ, Son EW, Lee SR, Lee SM, Shin DH, Pyo S. CML-1 inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in endothelial cells through inhibition of IkBalpha kinase. J Ethnopharmacol 109: 78–86, 2007.
    • (2007) J Ethnopharmacol , vol.109 , pp. 78-86
    • Mo, S.J.1    Son, E.W.2    Lee, S.R.3    Lee, S.M.4    Shin, D.H.5    Pyo, S.6
  • 20
    • 0038180539 scopus 로고    scopus 로고
    • Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response
    • Muller WA. Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. Trends Immunol 24: 327–334, 2003.
    • (2003) Trends Immunol , vol.24 , pp. 327-334
    • Muller, W.A.1
  • 21
    • 0026799260 scopus 로고
    • Induction of ICAM-1 by TNF-β, IL-1-+, and LPS in human endothelial cells after downregulation of PKC
    • Myers CL, Wertheimer SJ, Schembri-King J, Parks T, Wallace RW. Induction of ICAM-1 by TNF-β, IL-1-+, and LPS in human endothelial cells after downregulation of PKC. Am J Physiol 263: C767–C772, 1992.
    • (1992) Am J Physiol , vol.263 , pp. C767-C772
    • Myers, C.L.1    Wertheimer, S.J.2    Schembri-King, J.3    Parks, T.4    Wallace, R.W.5
  • 23
    • 0032583949 scopus 로고    scopus 로고
    • Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1
    • Nakano H, Shindo M, Sakon S, Nishinaka S, Mihara M, Yagita H, Okumura K. Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1. Proc Natl Acad Sci USA 95: 3537-3542, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3537-3542
    • Nakano, H.1    Shindo, M.2    Sakon, S.3    Nishinaka, S.4    Mihara, M.5    Yagita, H.6    Okumura, K.7
  • 24
    • 84877757564 scopus 로고    scopus 로고
    • Molecular basis of NF-kappaB signaling
    • Napetschnig J, Wu H. Molecular basis of NF-kappaB signaling. Annu Rev Biophys 42: 443–468, 2013.
    • (2013) Annu Rev Biophys , vol.42 , pp. 443-468
    • Napetschnig, J.1    Wu, H.2
  • 25
    • 84864880070 scopus 로고    scopus 로고
    • Scientific letter: Ac-SDKP (N-acetylseryl-aspartyl-lysyl-proline) and Galectin-3 levels in tuberculous pericardial effusion: Implications for pathogenesis and prevention of pericardial constriction
    • Ntsekhe M, Matthews K, Wolske J, Badri M, Wilkinson KA, Wilkinson RJ, Sturrock ED, Mayosi BM. Scientific letter: Ac-SDKP (N-acetylseryl-aspartyl-lysyl-proline) and Galectin-3 levels in tuberculous pericardial effusion: implications for pathogenesis and prevention of pericardial constriction. Heart 98: 1326–1328, 2012.
    • (2012) Heart , vol.98 , pp. 1326-1328
    • Ntsekhe, M.1    Matthews, K.2    Wolske, J.3    Badri, M.4    Wilkinson, K.A.5    Wilkinson, R.J.6    Sturrock, E.D.7    Mayosi, B.M.8
  • 26
    • 33847059651 scopus 로고    scopus 로고
    • Role of N-acetyl-seryl-aspartyl-lysyl-proline in the antifibrotic and anti-inflammatory effects of the angiotensin-converting enzyme inhibitor captopril in hypertension
    • Peng H, Carretero OA, Liao TD, Peterson EL, Rhaleb NE. Role of N-acetyl-seryl-aspartyl-lysyl-proline in the antifibrotic and anti-inflammatory effects of the angiotensin-converting enzyme inhibitor captopril in hypertension. Hypertension 49: 695–703, 2007.
    • (2007) Hypertension , vol.49 , pp. 695-703
    • Peng, H.1    Carretero, O.A.2    Liao, T.D.3    Peterson, E.L.4    Rhaleb, N.E.5
  • 27
    • 0035095260 scopus 로고    scopus 로고
    • Antifibrotic effects of N-acetyl-seryl-aspartyl-Lysyl-proline on the heart and kidney in aldosterone-salt hypertensive rats
    • Peng H, Carretero OA, Raij L, Yang F, Kapke A, Rhaleb NE. Antifibrotic effects of N-acetyl-seryl-aspartyl-Lysyl-proline on the heart and kidney in aldosterone-salt hypertensive rats. Hypertension 37: 794-800, 2001.
    • (2001) Hypertension , vol.37 , pp. 794-800
    • Peng, H.1    Carretero, O.A.2    Raij, L.3    Yang, F.4    Kapke, A.5    Rhaleb, N.E.6
  • 29
    • 0037024696 scopus 로고    scopus 로고
    • Regulation of Ikappa B kinase (IKK) gamma/ NEMO function by IKKbeta-mediated phosphorylation
    • Prajapati S, Gaynor RB. Regulation of Ikappa B kinase (IKK) gamma/ NEMO function by IKKbeta-mediated phosphorylation. J Biol Chem 277: 24331–24339, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 24331-24339
    • Prajapati, S.1    Gaynor, R.B.2
  • 30
    • 0345826130 scopus 로고    scopus 로고
    • Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity
    • Prajapati S, Verma U, Yamamoto Y, Kwak YT, Gaynor RB. Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity. J Biol Chem 279: 1739–1746, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 1739-1746
    • Prajapati, S.1    Verma, U.2    Yamamoto, Y.3    Kwak, Y.T.4    Gaynor, R.B.5
  • 31
    • 0032707168 scopus 로고    scopus 로고
    • Human vascular endothelial cells produce tumor necrosis factor-alpha in response to proinflammatory cytokine stimulation
    • Ranta V, Orpana A, Carpen O, Turpeinen U, Ylikorkala O, Viinikka L. Human vascular endothelial cells produce tumor necrosis factor-alpha in response to proinflammatory cytokine stimulation. Crit Care Med 27: 2184–2187, 1999.
    • (1999) Crit Care Med , vol.27 , pp. 2184-2187
    • Ranta, V.1    Orpana, A.2    Carpen, O.3    Turpeinen, U.4    Ylikorkala, O.5    Viinikka, L.6
  • 33
    • 0035954294 scopus 로고    scopus 로고
    • Long-term effect of N-acetyl-seryl-aspartyl-lysyl-proline on left ventricular collagen deposition in rats with 2-kidney, 1-clip hypertension
    • Rhaleb NE, Peng H, Yang XP, Liu YH, Mehta D, Ezan E, Carretero OA. Long-term effect of N-acetyl-seryl-aspartyl-lysyl-proline on left ventricular collagen deposition in rats with 2-kidney, 1-clip hypertension. Circulation 103: 3136–3141, 2001.
    • (2001) Circulation , vol.103 , pp. 3136-3141
    • Rhaleb, N.E.1    Peng, H.2    Yang, X.P.3    Liu, Y.H.4    Mehta, D.5    Ezan, E.6    Carretero, O.A.7
  • 34
  • 35
    • 42649124339 scopus 로고    scopus 로고
    • TNF: A master switch for inflammation to cancer
    • Sethi G, Sung B, Aggarwal BB. TNF: a master switch for inflammation to cancer. Front Biosci 13: 5094–5107, 2008.
    • (2008) Front Biosci , vol.13 , pp. 5094-5107
    • Sethi, G.1    Sung, B.2    Aggarwal, B.B.3
  • 38
    • 0032568485 scopus 로고    scopus 로고
    • Inflammation in cardiovascular disease: Cart, horse, or both?
    • Tracy RP. Inflammation in cardiovascular disease: cart, horse, or both? Circulation 97: 2000–2002, 1998.
    • (1998) Circulation , vol.97 , pp. 2000-2002
    • Tracy, R.P.1
  • 39
    • 0037851769 scopus 로고    scopus 로고
    • IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide
    • Yang F, Tang E, Guan K, Wang CY. IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide. J Immunol 170: 5630–5635, 2003.
    • (2003) J Immunol , vol.170 , pp. 5630-5635
    • Yang, F.1    Tang, E.2    Guan, K.3    Wang, C.Y.4
  • 40
    • 0842267835 scopus 로고    scopus 로고
    • Ac-SDKP reverses inflammation and fibrosis in rats with heart failure after myocardial infarction
    • Yang F, Yang XP, Liu YH, Xu J, Cingolani O, Rhaleb NE, Carretero OA. Ac-SDKP reverses inflammation and fibrosis in rats with heart failure after myocardial infarction. Hypertension 43: 229–236, 2004.
    • (2004) Hypertension , vol.43 , pp. 229-236
    • Yang, F.1    Yang, X.P.2    Liu, Y.H.3    Xu, J.4    Cingolani, O.5    Rhaleb, N.E.6    Carretero, O.A.7
  • 41
    • 19644367000 scopus 로고    scopus 로고
    • Activation and signaling of the p38 MAP kinase pathway
    • Zarubin T, Han J. Activation and signaling of the p38 MAP kinase pathway. Cell Res 15: 11–18, 2005.
    • (2005) Cell Res , vol.15 , pp. 11-18
    • Zarubin, T.1    Han, J.2
  • 42
    • 34147099560 scopus 로고    scopus 로고
    • TNFR1-induced NF-kappaB, but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells
    • Zhou Z, Connell MC, MacEwan DJ. TNFR1-induced NF-kappaB, but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells. Cell Signal 19: 1238–1248, 2007.
    • (2007) Cell Signal , vol.19 , pp. 1238-1248
    • Zhou, Z.1    Connell, M.C.2    Macewan, D.J.3
  • 43
    • 33846955449 scopus 로고    scopus 로고
    • Characterization and localization of Ac-SDKP receptor binding sites using 125I-labeled Hpp-Aca-SDKP in rat cardiac fibroblasts
    • Zhuo JL, Carretero OA, Peng H, Li XC, Regoli D, Neugebauer W, Rhaleb NE. Characterization and localization of Ac-SDKP receptor binding sites using 125I-labeled Hpp-Aca-SDKP in rat cardiac fibroblasts. Am J Physiol Heart Circ Physiol 292: H984–H993, 2007.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , pp. H984-H993
    • Zhuo, J.L.1    Carretero, O.A.2    Peng, H.3    Li, X.C.4    Regoli, D.5    Neugebauer, W.6    Rhaleb, N.E.7


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