N-acetyl-Ser-Asp-Lys-Pro inhibits interleukin-1β-mediated matrix metalloproteinase activation in cardiac fibroblasts

Pflugers Archiv European Journal of Physiology

Volumn 465, Issue 10, 2013, Pages 1487-1495

  Rhaleb, Nour Eddine ^a,b   Pokharel, Saraswati ^a   Sharma, Umesh C ^a   Peng, Hongmei ^a   Peterson, Edward ^a   Harding, Pamela ^a   Yang, Xiao Ping ^a   Carretero, Oscar A ^a  

^a HENRY FORD HOSPITAL   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiac fibroblasts; MAPK; Matrix metalloproteinases; Myocardial matrix turnover; N acetyl Ser Asp Lys Pro; NF B; Synthesis and degradation

Indexed keywords

COLLAGEN; COLLAGENASE; COLLAGENASE 3; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SERASPENIDE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL CELL; ARTICLE; CARDIAC FIBROBLAST; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FIBROBLAST; GENETIC TRANSCRIPTION; HEART MUSCLE CELL; INTRACELLULAR SIGNALING; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT;

ANIMALS; COLLAGEN; COLLAGENASES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GELATINASES; INTERLEUKIN-1BETA; MALE; MATRIX METALLOPROTEINASES; MYOCARDIUM; NF-KAPPA B; OLIGOPEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 84884883332     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-013-1262-8     Document Type: Article

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