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Volumn 10, Issue , 2016, Pages

Towards understanding brain-gut-microbiome connections in Alzheimer's disease

Author keywords

Alzheimer's disease; Disease etiology; Human gut micriobiome; Network medicine; Systems biology

Indexed keywords

METHYLAMINE; TRIMETHYLOXAMINE;

EID: 84983656993     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/s12918-016-0307-y     Document Type: Article
Times cited : (150)

References (45)
  • 2
    • 84866168894 scopus 로고    scopus 로고
    • Functional interactions between the gut microbiota and host metabolism
    • Tremaroli V, Backhed F. Functional interactions between the gut microbiota and host metabolism. Nature. 2012; 489(7415):242-9.
    • (2012) Nature , vol.489 , Issue.7415 , pp. 242-249
    • Tremaroli, V.1    Backhed, F.2
  • 3
    • 84866546211 scopus 로고    scopus 로고
    • Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
    • Cryan JF, Dinan TG. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci. 2012; 13(10):701-12.
    • (2012) Nat Rev Neurosci , vol.13 , Issue.10 , pp. 701-712
    • Cryan, J.F.1    Dinan, T.G.2
  • 5
    • 84894118144 scopus 로고    scopus 로고
    • Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders
    • Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, Mazmanian SK. Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell. 2013; 155(7):1451-63.
    • (2013) Cell , vol.155 , Issue.7 , pp. 1451-1463
    • Hsiao, E.Y.1    McBride, S.W.2    Hsien, S.3    Sharon, G.4    Hyde, E.R.5    McCue, T.6    Mazmanian, S.K.7
  • 6
    • 80051831092 scopus 로고    scopus 로고
    • Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease
    • Dudley JT, Sirota M, Shenoy M, Pai RK, Roedder S, Chiang AP, Butte AJ. Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease. Sci Transl Med. 2011; 3(96):96-769676.
    • (2011) Sci Transl Med , vol.3 , Issue.96 , pp. 96-769676
    • Dudley, J.T.1    Sirota, M.2    Shenoy, M.3    Pai, R.K.4    Roedder, S.5    Chiang, A.P.6    Butte, A.J.7
  • 7
    • 84867338003 scopus 로고    scopus 로고
    • Discovery and preclinical validation of drug indications using compendia of public gene expression data
    • Sirota M, Dudley JT, Kim J, Chiang AP, Morgan AA, Sweet-Cordero A, Butte AJ. Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sci Transl Med. 2011; 3(96):96-779677.
    • (2011) Sci Transl Med , vol.3 , Issue.96 , pp. 96-779677
    • Sirota, M.1    Dudley, J.T.2    Kim, J.3    Chiang, A.P.4    Morgan, A.A.5    Sweet-Cordero, A.6    Butte, A.J.7
  • 8
    • 84983663790 scopus 로고    scopus 로고
    • DenguePredict: an integrated drug repositioning system towards drug discovery for dengue.
    • Wang Q, Xu R. DenguePredict: an integrated drug repositioning system towards drug discovery for dengue. AMIA Annu Symp Proc. 2015: 2015. p. 1279-88.
    • (2015) AMIA Annu Symp Proc , pp. 1279-1288
    • Wang, Q.1    Xu, R.2
  • 9
    • 84938584604 scopus 로고    scopus 로고
    • Phenopredict: a disease phenome-wide drug repositioning approach towards schizophrenia drug discovery.
    • Xu R, Wang Q. Phenopredict: a disease phenome-wide drug repositioning approach towards schizophrenia drug discovery. J Biomed Inform. 2015:348-55. [doi: 10.1016/j.jbi.2015.06.027 ].
    • (2015) J Biomed Inform , pp. 348-355
    • Xu, R.1    Wang, Q.2
  • 10
    • 84983077914 scopus 로고    scopus 로고
    • Combing Human Disease Genetics and Mouse Model Phenotypes Towards Drug Repositioning for Parkinson's Disease
    • Chen Y, Cai X, Xu R. Combing Human Disease Genetics and Mouse Model Phenotypes Towards Drug Repositioning for Parkinson's Disease. AMIA Annu Symp Proc. 2015: 2015. p. 1851-60.
    • (2015) AMIA Annu Symp Proc , pp. 1851-1860
    • Chen, Y.1    Cai, X.2    Xu, R.3
  • 11
    • 84863987708 scopus 로고    scopus 로고
    • Computational tools for prioritizing candidate genes: boosting disease gene discovery
    • Moreau Y, Tranchevent LC. Computational tools for prioritizing candidate genes: boosting disease gene discovery. Nat Rev Genet. 2012; 13(8):523-36.
    • (2012) Nat Rev Genet , vol.13 , Issue.8 , pp. 523-536
    • Moreau, Y.1    Tranchevent, L.C.2
  • 12
    • 84931089568 scopus 로고    scopus 로고
    • Phenome-driven disease genetics prediction towards drug discovery
    • Chen Y, Xu R. Phenome-driven disease genetics prediction towards drug discovery. Bioinformatics. 2015; 31(12):i276-83.
    • (2015) Bioinformatics , vol.31 , Issue.12 , pp. i276-i283
    • Chen, Y.1    Xu, R.2
  • 13
    • 84969141960 scopus 로고    scopus 로고
    • Network-based gene prediction for plasmodium falciparum malaria towards genetics-based drug discovery
    • Chen Y, Xu R. Network-based gene prediction for plasmodium falciparum malaria towards genetics-based drug discovery. BMC Genomics. 2015; 16(Suppl 7):9.
    • (2015) BMC Genomics , vol.16 , pp. 9
    • Chen, Y.1    Xu, R.2
  • 14
    • 84969261931 scopus 로고    scopus 로고
    • Genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine n-oxide (tmao), a gut microbial metabolite of dietary meat and fat
    • Xu R, Wang Q, Li L. Genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine n-oxide (tmao), a gut microbial metabolite of dietary meat and fat. BMC Genomics. 2015; 16(Suppl 7):4.
    • (2015) BMC Genomics , vol.16 , pp. 4
    • Xu, R.1    Wang, Q.2    Li, L.3
  • 18
    • 13444266370 scopus 로고    scopus 로고
    • Online mendelian inheritance in man (omim), a knowledgebase of human genes and genetic disorders
    • Hamosh A, Scott AF, Amberger JS, Bocchini CA, McKusick VA. Online mendelian inheritance in man (omim), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res. 2005; 33(suppl 1):514-7.
    • (2005) Nucleic Acids Res , vol.33 , pp. 514-517
    • Hamosh, A.1    Scott, A.F.2    Amberger, J.S.3    Bocchini, C.A.4    McKusick, V.A.5
  • 19
    • 84876515907 scopus 로고    scopus 로고
    • String v9. 1: protein-protein interaction networks, with increased coverage and integration
    • Franceschini A, Szklarczyk D, Frankild S, Kuhn M, Simonovic M. String v9. 1: protein-protein interaction networks, with increased coverage and integration. Nucleic Acids Res. 2013; 41(D1):808-15.
    • (2013) Nucleic Acids Res , vol.41 , pp. 808-815
    • Franceschini, A.1    Szklarczyk, D.2    Frankild, S.3    Kuhn, M.4    Simonovic, M.5
  • 21
    • 0003585297 scopus 로고    scopus 로고
    • Data Mining: Concepts and Techniques: Concepts and Techniques: Elsevier
    • Han J, Kamber M, Pei J. Data Mining: Concepts and Techniques: Concepts and Techniques: Elsevier; 2011.
    • (2011)
    • Han, J.1    Kamber, M.2    Pei, J.3
  • 22
    • 0030038202 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in alzheimer disease
    • Shetty HU, Holloway HW, Schapiro MB. Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in alzheimer disease. Clin Chem. 1996; 42(2):298-302.
    • (1996) Clin Chem , vol.42 , Issue.2 , pp. 298-302
    • Shetty, H.U.1    Holloway, H.W.2    Schapiro, M.B.3
  • 23
    • 0031664279 scopus 로고    scopus 로고
    • Abnormal substrate levels that depend upon mitochondrial function in cerebrospinal fluid from alzheimer patients
    • Redjems-Bennani N, Jeandel C, Lefebvre E, Blain H, Vidailhet M, Gueant JL. Abnormal substrate levels that depend upon mitochondrial function in cerebrospinal fluid from alzheimer patients. Gerontology. 1998; 44(5):300-4.
    • (1998) Gerontology , vol.44 , Issue.5 , pp. 300-304
    • Redjems-Bennani, N.1    Jeandel, C.2    Lefebvre, E.3    Blain, H.4    Vidailhet, M.5    Gueant, J.L.6
  • 24
    • 0032824307 scopus 로고    scopus 로고
    • Patterns of cerebrospinal fluid catechols support increased central noradrenergic responsiveness in aging and alzheimer's disease
    • Raskind MA, Peskind ER, Holmes C, Goldstein DS. Patterns of cerebrospinal fluid catechols support increased central noradrenergic responsiveness in aging and alzheimer's disease. Biol Psychiatry. 1999; 46(6):756-65.
    • (1999) Biol Psychiatry , vol.46 , Issue.6 , pp. 756-765
    • Raskind, M.A.1    Peskind, E.R.2    Holmes, C.3    Goldstein, D.S.4
  • 25
    • 33646827677 scopus 로고    scopus 로고
    • Parkin suppresses the expression of monoamine oxidases
    • Jiang H, Jiang Q, Liu W, Feng J. Parkin suppresses the expression of monoamine oxidases. J Biol Chem. 2006; 281(13):8591-9.
    • (2006) J Biol Chem , vol.281 , Issue.13 , pp. 8591-8599
    • Jiang, H.1    Jiang, Q.2    Liu, W.3    Feng, J.4
  • 27
    • 39149099114 scopus 로고    scopus 로고
    • Bile acids and apoptosis modulation: an emerging role in experimental alzheimer's disease
    • Ramalho RM, Viana RJ, Low WC, Steer CJ, Rodrigues CM. Bile acids and apoptosis modulation: an emerging role in experimental alzheimer's disease. Trends Mol Med. 2008; 14(2):54-62.
    • (2008) Trends Mol Med , vol.14 , Issue.2 , pp. 54-62
    • Ramalho, R.M.1    Viana, R.J.2    Low, W.C.3    Steer, C.J.4    Rodrigues, C.M.5
  • 28
    • 33746880721 scopus 로고    scopus 로고
    • Urinary polyamines and n-acetylated polyamines in four patients with alzheimer's disease as their n-ethoxycarbonyl-n-pentafluoropropionyl derivatives by gas chromatography-mass spectrometry in selected ion monitoring mode
    • Paik MJ, Lee S, Cho KH, Kim KR. Urinary polyamines and n-acetylated polyamines in four patients with alzheimer's disease as their n-ethoxycarbonyl-n-pentafluoropropionyl derivatives by gas chromatography-mass spectrometry in selected ion monitoring mode. Analytica Chimica Acta. 2006; 576(1):55-60.
    • (2006) Analytica Chimica Acta , vol.576 , Issue.1 , pp. 55-60
    • Paik, M.J.1    Lee, S.2    Cho, K.H.3    Kim, K.R.4
  • 30
    • 0026688245 scopus 로고
    • Antioxidant potential of ferulic acid
    • Graf E. Antioxidant potential of ferulic acid. Free Radic Biol Med. 1992; 13(4):435-48.
    • (1992) Free Radic Biol Med , vol.13 , Issue.4 , pp. 435-448
    • Graf, E.1
  • 32
    • 34147157711 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate activates akt and improves spatial learning in app/ps1 mice without affecting beta-amyloid burden
    • Malm TM, Iivonen H, Goldsteins G, Keksa-Goldsteine V, Ahtoniemi T, Kanninen K, Koistinaho J. Pyrrolidine dithiocarbamate activates akt and improves spatial learning in app/ps1 mice without affecting beta-amyloid burden. J Neurosci. 2007; 27(14):3712-21.
    • (2007) J Neurosci , vol.27 , Issue.14 , pp. 3712-3721
    • Malm, T.M.1    Iivonen, H.2    Goldsteins, G.3    Keksa-Goldsteine, V.4    Ahtoniemi, T.5    Kanninen, K.6    Koistinaho, J.7
  • 35
    • 84865405744 scopus 로고    scopus 로고
    • Alzheimer's disease, beta-amyloid, glutamate, nmda receptors and memantine searching for the connections
    • Danysz W, Parsons CG. Alzheimer's disease, beta-amyloid, glutamate, nmda receptors and memantine searching for the connections. Br J Pharmacol. 2012; 167(2):324-52.
    • (2012) Br J Pharmacol , vol.167 , Issue.2 , pp. 324-352
    • Danysz, W.1    Parsons, C.G.2
  • 37
    • 84872139636 scopus 로고    scopus 로고
    • Trimethylamine-n-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation
    • Bennett BJ, de Aguiar Vallim TQ, Z W, Shih DM, Meng Y, Gregory J, Lusis AJ. Trimethylamine-n-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. Cell Metabolism. 2013; 17(1):49-60.
    • (2013) Cell Metabolism , vol.17 , Issue.1 , pp. 49-60
    • Bennett, B.J.1    de Aguiar Vallim, T.Q.2    Z, W.3    Shih, D.M.4    Meng, Y.5    Gregory, J.6    Lusis, A.J.7
  • 38
    • 84877331372 scopus 로고    scopus 로고
    • Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis
    • Koeth RA, Wang Z, Levison BS, Buffa JA, Sheehy BT, Britt EB, Hazen SL. Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis. Nat Med. 2013; 19(5):576-85.
    • (2013) Nat Med , vol.19 , Issue.5 , pp. 576-585
    • Koeth, R.A.1    Wang, Z.2    Levison, B.S.3    Buffa, J.A.4    Sheehy, B.T.5    Britt, E.B.6    Hazen, S.L.7
  • 39
  • 42
    • 2342555602 scopus 로고    scopus 로고
    • Dietary fat intake and 6-year cognitive change in an older biracial community population
    • Morris MC, Evans DA, Bienias JL, Tangney CC, Wilson RS. Dietary fat intake and 6-year cognitive change in an older biracial community population. Neurology. 2004; 62(9):1573-9.
    • (2004) Neurology , vol.62 , Issue.9 , pp. 1573-1579
    • Morris, M.C.1    Evans, D.A.2    Bienias, J.L.3    Tangney, C.C.4    Wilson, R.S.5
  • 45
    • 84924061484 scopus 로고    scopus 로고
    • The mediterranean diet, its components, and cardiovascular disease
    • Widmer RJ, Flammer AJ, Lerman LO, Lerman A. The mediterranean diet, its components, and cardiovascular disease. Am J Med. 2015; 128(3):229-38.
    • (2015) Am J Med , vol.128 , Issue.3 , pp. 229-238
    • Widmer, R.J.1    Flammer, A.J.2    Lerman, L.O.3    Lerman, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.