Prolyl hydroxylase 2 (PHD2) inhibition protects human renal epithelial cells and mice kidney from hypoxia injury

Oncotarget

Volumn 7, Issue 34, 2016, Pages 54317-54328

  Fang, Yi ^a,b,c   Zhang, Hui ^a,d   Zhong, Yihong ^a   Ding, Xiaoqiang ^a,b,c  

^a FUDAN UNIVERSITY   (China)

^b Kidney and Dialysis Institute of Shanghai   (China)

^c Kidney and Blood Purification Laboratory of Shanghai   (China)

^d QINGDAO UNIVERSITY   (China)

Author keywords

Autophagy and apoptosis; Hypoxia inducible factor; Pathology Section; Prolyl hydroxylase 2; Renal ischemia reperfusion injury

Indexed keywords

3 METHYLADENINE; COBALT CHLORIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MIMOSINE; OXYGENASE; PROLYL HYDROXYLASE DOMAIN PROTEIN 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; COBALT; EGLN1 PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE; PROLYL HYDROXYLASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL ACTIVATION; CELL DAMAGE; CELL HYPOXIA; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFECT; ENZYME INDUCTION; ENZYME INHIBITION; EPITHELIUM CELL; HK 2 CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; KIDNEY EPITHELIUM; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY TUBULE CELL; MALE; MOUSE; NEPHRITIS; NONHUMAN; PROTEIN EXPRESSION; REPERFUSION INJURY; ANIMAL; DRUG EFFECTS; KIDNEY; PHYSIOLOGY; VASCULARIZATION;

ANIMALS; APOPTOSIS; CELL HYPOXIA; COBALT; CYTOPROTECTION; EPITHELIAL CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; KIDNEY; MICE; MIMOSINE; PROLYL-HYDROXYLASE INHIBITORS; REPERFUSION INJURY;

EID: 84983541724     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11104     Document Type: Article

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