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Volumn 13, Issue 2, 2016, Pages 156-163

Insulin-mimetic activity of stevioside on diabetic rats: Biochemical, molecular and histopathological study

Author keywords

Diabetes; Insulin like activity; Molecular effects; Stevioside

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CARNITYLPALMITYL TRANSFERASE 1; CATALASE; CHOLESTEROL; CREATININE; GLUCOSE; GLUTATHIONE REDUCTASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; LEPTIN; LIPID; MALONALDEHYDE; MESSENGER RNA; METFORMIN; ORAL ANTIDIABETIC AGENT; PYRUVATE KINASE; STEVIOSIDE; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UREA;

EID: 84983442568     PISSN: None     EISSN: 01896016     Source Type: Journal    
DOI: 10.4314/ajtcam.v13i2.19     Document Type: Article
Times cited : (7)

References (50)
  • 1
    • 33750348125 scopus 로고    scopus 로고
    • Some toxicological studies of Momordicacharantia L. On albino rats in normal and alloxan diabetic rats
    • Abdelsattarelbatran, S., Elgengaihi, S and Elshabrawy, O. (2006). Some toxicological studies of Momordicacharantia L. on albino rats in normal and alloxan diabetic rats. J Ethnopharmacol 108: 236-242.
    • (2006) J Ethnopharmacol , vol.108 , pp. 236-242
    • Abdelsattarelbatran, S.1    Elgengaihi, S.2    Elshabrawy, O.3
  • 2
    • 77952951962 scopus 로고    scopus 로고
    • Insulinotropic effect of cinnamaldehyde on transcriptional regulation of pyruvate kinase, phosphoenolpyruvatecarboxykinase and GLUT4 translocation in experimental diabetic rats
    • Anand, P., Murali, K.Y., Tandon, V., Murthy, P.S and Chandra R. (2010). Insulinotropic effect of cinnamaldehyde on transcriptional regulation of pyruvate kinase, phosphoenolpyruvatecarboxykinase and GLUT4 translocation in experimental diabetic rats. Chemico-Biol Interact 186: 72-81.
    • (2010) Chemico-Biol Interact , vol.186 , pp. 72-81
    • Anand, P.1    Murali, K.Y.2    Tandon, V.3    Murthy, P.S.4    Chandra, R.5
  • 3
    • 77953962912 scopus 로고    scopus 로고
    • Effects of stevioside, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels
    • Anton, S.D., Martin, C.K., Han, H. S., Coulon, Cefalu W.T., Geiselman, P and Williamson, D.A. (2010). Effects of stevioside, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels. Appetite. 55: 37-43.
    • (2010) Appetite , vol.55 , pp. 37-43
    • Anton, S.D.1    Martin, C.K.2    Han, H.S.3    Coulon, C.W.T.4    Geiselman, P.5    Williamson, D.A.6
  • 4
    • 85016321860 scopus 로고    scopus 로고
    • Stevioside as a low caloric sweetener to milky drink and its protective role against oxidative stress in diabetic rats
    • Badawi, A.M., El-Tablawy, N.A., Bassily N.S and El-Behairy S.A. (2005). Stevioside as a low caloric sweetener to milky drink and its protective role against oxidative stress in diabetic rats. Egyptian J Hospital Med 20: 163–176.
    • (2005) Egyptian J Hospital Med , vol.20 , pp. 163-176
    • Badawi, A.M.1    El-Tablawy, N.A.2    Bassily, N.S.3    El-Behairy, S.A.4
  • 5
    • 0024330279 scopus 로고
    • Traditional treatments for diabetes
    • Bailey, C.J and Day, C. (1989). Traditional treatments for diabetes. Diab Care 12: 553-564.
    • (1989) Diab Care , vol.12 , pp. 553-564
    • Bailey, C.J.1    Day, C.2
  • 7
    • 33646892396 scopus 로고    scopus 로고
    • Stevia-the calorie free natural sweetener
    • Bharathi, N. (2003). Stevia-the calorie free natural sweetener. Nat Prod Red 2: 120-123.
    • (2003) Nat Prod Red , vol.2 , pp. 120-123
    • Bharathi, N.1
  • 8
    • 0242285563 scopus 로고    scopus 로고
    • Oxidative damage and altered antioxidant enzyme activities in the small intestine of streptozotocin-induced diabetic rats
    • Bhor, V.M., Raghuram, N and Sivakami, S. (2004). Oxidative damage and altered antioxidant enzyme activities in the small intestine of streptozotocin-induced diabetic rats. Inter J Biochem Cell Biol 36: 89-97.
    • (2004) Inter J Biochem Cell Biol , vol.36 , pp. 89-97
    • Bhor, V.M.1    Raghuram, N.2    Sivakami, S.3
  • 9
    • 16644369717 scopus 로고    scopus 로고
    • Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models
    • Can, A., Akev, N., Ozsoy, N., Bolkent, S., Arda, B.P., Yanardag, R and Okyar S. (2004). Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models. Biol Pharmaceut Bull 27: 694-698.
    • (2004) Biol Pharmaceut Bull , vol.27 , pp. 694-698
    • Can, A.1    Akev, N.2    Ozsoy, N.3    Bolkent, S.4    Arda, B.P.5    Yanardag, R.6    Okyar, S.7
  • 10
    • 27744601132 scopus 로고    scopus 로고
    • Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats
    • Chang, J.C., Wu, M.C., Liu, I.M and Cheng, J.T. (2005). Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats. Horm Metabol Res 37: 610-616.
    • (2005) Horm Metabol Res , vol.37 , pp. 610-616
    • Chang, J.C.1    Wu, M.C.2    Liu, I.M.3    Cheng, J.T.4
  • 11
    • 14944361919 scopus 로고    scopus 로고
    • Mechanism of the hypoglycemic effect of stevioside, a glycoside of Stevia rebaudian
    • Chen, T.H., Chen, S.C., Chan, P., Chu, Y.L., Yang H.Y and Cheng, J. (2005). Mechanism of the hypoglycemic effect of stevioside, a glycoside of Stevia rebaudian. Plant Med 71: 108-113.
    • (2005) Plant Med , vol.71 , pp. 108-113
    • Chen, T.H.1    Chen, S.C.2    Chan, P.3    Chu, Y.L.4    Yang, H.Y.5    Cheng, J.6
  • 12
    • 84873933054 scopus 로고    scopus 로고
    • Hepato-protective activity of Stevia rebaudianabert. Leaves against thioacetamide induced toxicity
    • Das, K and Kathiriya, A.K. (2012). Hepato-protective activity of Stevia rebaudianabert. leaves against thioacetamide induced toxicity. Turkish J Pharmaceut Sci. 9: 343-352.
    • (2012) Turkish J Pharmaceut Sci , vol.9 , pp. 343-352
    • Das, K.1    Kathiriya, A.K.2
  • 13
    • 7044235451 scopus 로고    scopus 로고
    • Strategies for managing diabetic patients on petritoneal dialysis
    • Dasgupta, M.K. (2004). Strategies for managing diabetic patients on petritoneal dialysis. Adv. Perit Dial 20: 200-220.
    • (2004) Adv. Perit Dial , vol.20 , pp. 200-220
    • Dasgupta, M.K.1
  • 14
    • 84983415535 scopus 로고    scopus 로고
    • Handbook of phytochemical constituents of gras herbs and other economic plants
    • Duke, J.A. (2006). Handbook of phytochemical constituents of gras herbs and other economic plants. FL CRC PressBoca Raton.
    • (2006) FL CRC Pressboca Raton
    • Duke, J.A.1
  • 15
    • 84956714738 scopus 로고    scopus 로고
    • Comparative efficacy of aqueous extract of stevioside (Stevia rebaudianaBertoni) leaves and metformin hydrochloride in streptozotocin induced diabetes mellitus in rats
    • Dutta, P.K., Razu, M.M.T., Alam, M.K., Awal, M.A and Mostofa, M. (2010). Comparative efficacy of aqueous extract of stevioside (Stevia rebaudianaBertoni) leaves and metformin hydrochloride in streptozotocin induced diabetes mellitus in rats. Inter J Biol Res 2: 17-22.
    • (2010) Inter J Biol Res , vol.2 , pp. 17-22
    • Dutta, P.K.1    Razu, M.M.T.2    Alam, M.K.3    Awal, M.A.4    Mostofa, M.5
  • 16
    • 23944450589 scopus 로고    scopus 로고
    • Preventive effects of soy based diet supplemented with stevioside on development of type 2 diabetes
    • Dyrskog, S.E., Jeppensen, P.B., Colombo, M., Abudula, R and Hermansen, K. (2005). Preventive effects of soy based diet supplemented with stevioside on development of type 2 diabetes. Metab 54: 1181-1188.
    • (2005) Metab , vol.54 , pp. 1181-1188
    • Dyrskog, S.E.1    Jeppensen, P.B.2    Colombo, M.3    Abudula, R.4    Hermansen, K.5
  • 17
    • 65349182940 scopus 로고    scopus 로고
    • Curcumin inhibits adipogenesis in 3 T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice
    • Ejaz, A., Wu, D., Kwan, P and Meydani, M. (2009). Curcumin inhibits adipogenesis in 3 T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice. J Nutr 139: 919–925.
    • (2009) J Nutr , vol.139 , pp. 919-925
    • Ejaz, A.1    Wu, D.2    Kwan, P.3    Meydani, M.4
  • 18
    • 0031975069 scopus 로고    scopus 로고
    • The effects of improved glycemic control on complications in type 2 diabetes
    • Gaster, B and Hirsch, I.B. (1998). The effects of improved glycemic control on complications in type 2 diabetes. Arch Inter Med 158: 134-140.
    • (1998) Arch Inter Med , vol.158 , pp. 134-140
    • Gaster, B.1    Hirsch, I.B.2
  • 19
    • 0347316397 scopus 로고    scopus 로고
    • Anti-hyperglycemic effects of stevioside in type 2 diabetic subjects
    • Gregersen, S., Jappesen, P.B., Holst, J.J and Hermansen, K. (2004). Anti-hyperglycemic effects of stevioside in type 2 diabetic subjects. Metab 53:73-76.
    • (2004) Metab , vol.53 , pp. 73-76
    • Gregersen, S.1    Jappesen, P.B.2    Holst, J.J.3    Hermansen, K.4
  • 20
    • 80155182980 scopus 로고    scopus 로고
    • Antihyperglycemic and anti-hyperlipidemic effects of different fractions of Steviarebaudiana leaves in alloxan induced diabetic rats
    • Hossain, M.S., Alam, M.B., Asadujjaman, M., Islam, M.M., Rahman, M.A., Islam, M.A and Islam, A. (2011). Antihyperglycemic and anti-hyperlipidemic effects of different fractions of Steviarebaudiana leaves in alloxan induced diabetic rats. IJPSR 2: 1722-1729.
    • (2011) IJPSR , vol.2 , pp. 1722-1729
    • Hossain, M.S.1    Alam, M.B.2    Asadujjaman, M.3    Islam, M.M.4    Rahman, M.A.5    Islam, M.A.6    Islam, A.7
  • 21
    • 84925105050 scopus 로고    scopus 로고
    • Molecular and immunohistochemical effects of metformin in a rat model of type 2 diabetes mellitus
    • Ismail, T.A., Soliman, M.M and Nassan, M.A. (2015). Molecular and immunohistochemical effects of metformin in a rat model of type 2 diabetes mellitus. Exp Theor Med 9: 1921-1930.
    • (2015) Exp Theor Med , vol.9 , pp. 1921-1930
    • Ismail, T.A.1    Soliman, M.M.2    Nassan, M.A.3
  • 22
    • 0037354211 scopus 로고    scopus 로고
    • Anti-hyperglycaemic and blood pressure-reducing effects of stevioside in diabetic Gots-kakizaki rat
    • Jeppesen, P.B., Gregersen, S and Roefsen, S.E. (2003). Anti-hyperglycaemic and blood pressure-reducing effects of stevioside in diabetic Gots-kakizaki rat. Metab 52: 372-378.
    • (2003) Metab , vol.52 , pp. 372-378
    • Jeppesen, P.B.1    Gregersen, S.2    Roefsen, S.E.3
  • 24
    • 32544445860 scopus 로고    scopus 로고
    • Antidiabetic effect of cinnamon extract on blood glucose in db/db mice
    • Kim, S.H., Hyun S.H and Choung, S.Y. (2006). Antidiabetic effect of cinnamon extract on blood glucose in db/db mice. J Ethnopharmacol 8: 119-23.
    • (2006) J Ethnopharmacol , vol.8 , pp. 119-123
    • Kim, S.H.1    Hyun, S.H.2    Choung, S.Y.3
  • 25
    • 0347316396 scopus 로고    scopus 로고
    • Effect of stevioside on glucose transport activity in rat muscle
    • Lailerd, N., Saengsirisuwan, V and Slonigar, J.A. (2004). Effect of stevioside on glucose transport activity in rat muscle. Metab 53: 101-107.
    • (2004) Metab , vol.53 , pp. 101-107
    • Lailerd, N.1    Saengsirisuwan, V.2    Slonigar, J.A.3
  • 26
    • 0035672675 scopus 로고    scopus 로고
    • Inhibitory effect of stevioside on calcium influx to produce anti hypertension
    • Lee, C.N., Wong, K., Liu, J., Chen, Y., Chen, J and Chan, P. (2001). Inhibitory effect of stevioside on calcium influx to produce anti hypertension. Planta Medica 67: 796-799.
    • (2001) Planta Medica , vol.67 , pp. 796-799
    • Lee, C.N.1    Wong, K.2    Liu, J.3    Chen, Y.4    Chen, J.5    Chan, P.6
  • 27
    • 85018213655 scopus 로고    scopus 로고
    • Isolation Perfused Gut. Absorption of glucose is inhibited by Steviol, a degradation product of the sweetener stevioside
    • Maier, V., Hermann, K and Kienle, U.D.O. (2003). Isolation Perfused Gut. absorption of glucose is inhibited by Steviol, a degradation product of the sweetener stevioside. Am Diabetes Ass 52: A554.
    • (2003) Am Diabetes Ass , vol.52
    • Maier, V.1    Hermann, K.2    Kienle, U.D.O.3
  • 28
    • 18244371101 scopus 로고    scopus 로고
    • Introducing Stevia rebaudiana, a natural Zero-calorie sweetener
    • Megaji, N.W., Kumar, J.K., Singh, V., Kaul V.K and Ahuja, P.S. (2005). Introducing Stevia rebaudiana, a natural Zero-calorie sweetener. Curr Sci India 88: 801-804.
    • (2005) Curr Sci India , vol.88 , pp. 801-804
    • Megaji, N.W.1    Kumar, J.K.2    Singh, V.3    Kaul, V.K.4    Ahuja, P.S.5
  • 29
    • 0021915511 scopus 로고
    • Direct evidence that reverse cholesterol transport is mediated by high-density lipoprotein in rabbit
    • Miller, N.E., La Ville, A and Crook, D. (1985). Direct evidence that reverse cholesterol transport is mediated by high-density lipoprotein in rabbit. Nature 314: 109-111.
    • (1985) Nature , vol.314 , pp. 109-111
    • Miller, N.E.1    La Ville, A.2    Crook, D.3
  • 30
    • 84860662374 scopus 로고    scopus 로고
    • Anti-hyperglycemic activity of six edible plants in validated animal models of diabetes mellitus
    • Mishra, A. (2009). Anti-hyperglycemic activity of six edible plants in validated animal models of diabetes mellitus. Indian J Sci Technol. 2: 80-86.
    • (2009) Indian J Sci Technol , vol.2 , pp. 80-86
    • Mishra, A.1
  • 31
    • 0035857020 scopus 로고    scopus 로고
    • New drug targets for type 2 diabetes and the metabolic syndrome
    • Moller, D.E. (2001). New drug targets for type 2 diabetes and the metabolic syndrome. Nature 414: 821-827.
    • (2001) Nature , vol.414 , pp. 821-827
    • Moller, D.E.1
  • 32
    • 84875231954 scopus 로고    scopus 로고
    • Anti-oxidant, anti-diabetic and renal protective properties of Stevia rebaudiana
    • Naveen, S., Naika, M., Khanum, F and Kaul, V.K. (2013). Anti-oxidant, anti-diabetic and renal protective properties of Stevia rebaudiana. J Diab Its Compl. 27: 103-113.
    • (2013) J Diab Its Compl , vol.27 , pp. 103-113
    • Naveen, S.1    Naika, M.2    Khanum, F.3    Kaul, V.K.4
  • 33
    • 84878393194 scopus 로고    scopus 로고
    • Carbohydrate concentration influences on in vitro plant regeneration in Stevia rebaudiana
    • Preethi, D., Sridhar, T.M and Naidu, C.V. (2011). Carbohydrate concentration influences on in vitro plant regeneration in Stevia rebaudiana. J Phytol 3: 61-64.
    • (2011) J Phytol , vol.3 , pp. 61-64
    • Preethi, D.1    Sridhar, T.M.2    Naidu, C.V.3
  • 34
    • 0030028606 scopus 로고    scopus 로고
    • The expression of TNF-alpha by human muscle: Relationship to insulin resistance
    • Saghizadeh, M., Ong, J.M., Garrey, W.T., Henry, R.R and Kern, P.A. (1996). The expression of TNF-alpha by human muscle: relationship to insulin resistance. J Clin Invest 97: 1111-1116.
    • (1996) J Clin Invest , vol.97 , pp. 1111-1116
    • Saghizadeh, M.1    Ong, J.M.2    Garrey, W.T.3    Henry, R.R.4    Kern, P.A.5
  • 35
    • 84856218516 scopus 로고    scopus 로고
    • Stevia rebaudiana: A medicinal and nutraceutical plant and sweet gold for diabetic patients. Inter
    • Seema, T.(2010). Stevia rebaudiana: A medicinal and nutraceutical plant and sweet gold for diabetic patients. Inter J Pharm. Life Sci. 1: 451-457.
    • (2010) J Pharm. Life Sci , vol.1 , pp. 451-457
    • Seema, T.1
  • 36
    • 84867331178 scopus 로고    scopus 로고
    • Study of effect of Steviarebaudianabertoni on oxidative stress in type-2 diabetic rat models
    • Sharma, R., Yadav, R and Manivannan, E. (2012). Study of effect of Steviarebaudianabertoni on oxidative stress in type-2 diabetic rat models. Biomed Aging Pathol. 2: 126-131.
    • (2012) Biomed Aging Pathol , vol.2 , pp. 126-131
    • Sharma, R.1    Yadav, R.2    Manivannan, E.3
  • 37
    • 84875231954 scopus 로고    scopus 로고
    • Antioxidant, anti diabetic and renal protective properties of Stevia rebaudiana
    • Shivanna, N., Naika M., Khanumand, F and Kaul, V.K. (2013). Antioxidant, anti diabetic and renal protective properties of Stevia rebaudiana. J Diab Comp 27: 103-113.
    • (2013) J Diab Comp , vol.27 , pp. 103-113
    • Shivanna, N.1    Naika, M.2    Khanumand, F.3    Kaul, V.K.4
  • 38
    • 67949101914 scopus 로고    scopus 로고
    • In vitro antioxidant activity and total phenolic content of ethanolic leaf extract of S. Rebaudiana Bert
    • Shukla, S., Mehta, A., Bajpai, V.K and Shukla, S. (2009). In vitro antioxidant activity and total phenolic content of ethanolic leaf extract of S. rebaudiana Bert. Food Chem Toxicol 47: 2338-2343.
    • (2009) Food Chem Toxicol , vol.47 , pp. 2338-2343
    • Shukla, S.1    Mehta, A.2    Bajpai, V.K.3    Shukla, S.4
  • 39
    • 79961106435 scopus 로고    scopus 로고
    • Evaluation of comparative anti-diabetic effects of ethanolic extracts of Caesalpiniabouncucella and Stevia rebaudianain normal and alloxan induced experimental rats
    • Shukla, S., Mehta, A., Mehta, P and Bajpai, V.K. (2011). Evaluation of comparative anti-diabetic effects of ethanolic extracts of Caesalpiniabouncucella and Stevia rebaudianain normal and alloxan induced experimental rats. Rom Biotechnol Letters. 16: 6187-6199.
    • (2011) Rom Biotechnol Letters , vol.16 , pp. 6187-6199
    • Shukla, S.1    Mehta, A.2    Mehta, P.3    Bajpai, V.K.4
  • 40
    • 84878414696 scopus 로고    scopus 로고
    • Anti-hyperglycemic and anti-oxidative ability of Steviarebaudiana (Bertoni) leaves in diabetes induced mice
    • Singh, S., Garg, V and Yadav, D. (2013). Anti-hyperglycemic and anti-oxidative ability of Steviarebaudiana (Bertoni) leaves in diabetes induced mice. Inter J Biol Sci. 5: 297-302.
    • (2013) Inter J Biol Sci , vol.5 , pp. 297-302
    • Singh, S.1    Garg, V.2    Yadav, D.3
  • 42
    • 84857817142 scopus 로고    scopus 로고
    • Biomedical effects of cinnamon extract on obesity and diabetes relevance in Wistar rats
    • Soliman, M.M., Attia, H.F., El-Shazly, S.A and Saleh, O.M. (2012). Biomedical effects of cinnamon extract on obesity and diabetes relevance in Wistar rats. American J Biochem Mol Biol 2: 133-145.
    • (2012) American J Biochem Mol Biol , vol.2 , pp. 133-145
    • Soliman, M.M.1    Attia, H.F.2    El-Shazly, S.A.3    Saleh, O.M.4
  • 43
    • 84878780163 scopus 로고    scopus 로고
    • Cinnamon extract regulates gene expression of lipid and carbohydrate metabolism in Streptozotocin induced diabetic Wistar rats
    • Soliman, M.M., Ahmed, M.M and El-Shazly S.A. (2013). Cinnamon extract regulates gene expression of lipid and carbohydrate metabolism in Streptozotocin induced diabetic Wistar rats. Am J Biochem Mol Biol 9: 172-182.
    • (2013) Am J Biochem Mol Biol , vol.9 , pp. 172-182
    • Soliman, M.M.1    Ahmed, M.M.2    El-Shazly, S.A.3
  • 44
    • 84924338413 scopus 로고    scopus 로고
    • Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats
    • Soliman, M.M., Nassan, M.A and Ismail, T.A. (2014). Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats. BMC Com Alt Med.14:457-467.
    • (2014) BMC Com Alt Med , vol.14 , pp. 457-467
    • Soliman, M.M.1    Nassan, M.A.2    Ismail, T.A.3
  • 46
    • 0347123324 scopus 로고    scopus 로고
    • Ethanolic extract of Ocimum sanctum leaves partially attenuates streptozotocininduced alterations in glycogen content and carbohydrate metabolism in rats
    • Vats, V., Yadav, S.P and Grover, J.K. (2004). Ethanolic extract of Ocimum sanctum leaves partially attenuates streptozotocininduced alterations in glycogen content and carbohydrate metabolism in rats. J Ethnopharmacol 90: 155-160.
    • (2004) J Ethnopharmacol , vol.90 , pp. 155-160
    • Vats, V.1    Yadav, S.P.2    Grover, J.K.3
  • 47
    • 0032906762 scopus 로고    scopus 로고
    • Nutrient and hormonal regulation of pyruvate kinase gene expression
    • Yamada, K and Noguchi, T. (1999). Nutrient and hormonal regulation of pyruvate kinase gene expression. Biochem J. 337: 1-11.
    • (1999) Biochem J , vol.337 , pp. 1-11
    • Yamada, K.1    Noguchi, T.2
  • 48
    • 0043053467 scopus 로고    scopus 로고
    • Inhibitory effect of stevioside on tumor promotion by 12-0-TCA in two stage carcinogenesis in mouse skin
    • Yasukawa, K., Kitanaka, S and Seo, S. (2002). Inhibitory effect of stevioside on tumor promotion by 12-0-TCA in two stage carcinogenesis in mouse skin. Biol Pharmaceut Bull. 25: 1488-1499.
    • (2002) Biol Pharmaceut Bull , vol.25 , pp. 1488-1499
    • Yasukawa, K.1    Kitanaka, S.2    Seo, S.3
  • 49
    • 0035856920 scopus 로고    scopus 로고
    • Shaw Global and Societal Implications of Diabetes Epidemic
    • Zimmet, P and Alberti, K.G. (2001). Shaw Global and societal implications of diabetes epidemic.Nature 414: 782-787.
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2
  • 50
    • 0347002050 scopus 로고    scopus 로고
    • Preventing Type 2 diabetes and the dysmetabolic syndrome in the real world: A ealistic view
    • Zimmet, P., Shaw, J and Alberti, K.G. (2003). Preventing Type 2 diabetes and the dysmetabolic syndrome in the real world: a ealistic view. Diab Med. 20: 693-702.
    • (2003) Diab Med , vol.20 , pp. 693-702
    • Zimmet, P.1    Shaw, J.2    Alberti, K.G.3


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