The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

Genes and Development

Volumn 30, Issue 15, 2016, Pages 1698-1703

  Signer, Robert A J ^a,b   Qi, Le ^a   Zhao, Zhiyu ^a   Thompson, David ^a   Sigova, Alla A ^c   Fan, Zi Peng ^c   Demartino, George N ^a   Young, Richard A ^c,d   Sonenberg, Nahum ^e   Morrison, Sean J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e MCGILL UNIVERSITY   (Canada)

Author keywords

4E BP; Protein synthesis; Stem cell

Indexed keywords

INITIATION FACTOR 4E BINDING PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 1; INITIATION FACTOR 4E BINDING PROTEIN 2; PROTEASOME; PROTEIN; RNA; UNCLASSIFIED DRUG; CARRIER PROTEIN; EIF4EBP1 PROTEIN, MOUSE; EIF4EBP2 PROTEIN, MOUSE; INITIATION FACTOR; PHOSPHOPROTEIN;

ADULT; ADULT STEM CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIVISION; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC STEM CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RNA ANALYSIS; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; GENE DELETION; GENETICS; METABOLISM; PHOSPHORYLATION;

ANIMALS; CARRIER PROTEINS; CELL DIFFERENTIATION; EUKARYOTIC INITIATION FACTORS; FEMALE; HEMATOPOIETIC STEM CELLS; MALE; MICE; MICE, INBRED C57BL; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BIOSYNTHESIS; SEQUENCE DELETION;

EID: 84983337909     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.282756.116     Document Type: Article

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