In vivo veritas, the next frontier for functionally selective GPCR ligands

Methods

Volumn 92, Issue , 2016, Pages 64-71

  Beaulieu, Jean Martin ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Animal models; Beta arrestin; Cell signaling; Functional selectivity; G protein coupled receptor

Indexed keywords

BETA ARRESTIN; G PROTEIN COUPLED RECEPTOR; PHOSPHOPROTEIN DARPP 32; PROTEIN KINASE B; DOPAMINE 2 RECEPTOR; HALOPERIDOL; LIGAND; PROTEIN BINDING; RETINA S ANTIGEN;

ANIMAL EXPERIMENT; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SURGICAL MESH; TARGET CELL; VALIDATION STUDY; AGONISTS; ANIMAL; ANIMAL MODEL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DRUG EFFECTS; HUMAN; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ARRESTINS; HALOPERIDOL; HUMANS; LIGANDS; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL; PROTEIN BINDING; RECEPTORS, DOPAMINE D2; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84983157009     PISSN: 10462023     EISSN: 10959130     Source Type: Journal    
DOI: 10.1016/j.ymeth.2015.08.018     Document Type: Article

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