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Volumn 3, Issue 3, 2016, Pages 186-197

Reprogramming towards endothelial cells for vascular regeneration

Author keywords

Atherosclerosis; Cell reprogramming; Endothelial cells; Endothelial regeneration; iPS cells; Stem cells

Indexed keywords

NOTCH RECEPTOR; TRANSCRIPTION FACTOR;

EID: 84983134148     PISSN: None     EISSN: 23523042     Source Type: Journal    
DOI: 10.1016/j.gendis.2016.02.003     Document Type: Review
Times cited : (15)

References (91)
  • 1
    • 33947716172 scopus 로고    scopus 로고
    • Endothelial function and dysfunction: testing and clinical relevance
    • 1 Deanfield, J.E., Halcox, J.P., Rabelink, T.J., Endothelial function and dysfunction: testing and clinical relevance. Circulation 115 (2007), 1285–1295.
    • (2007) Circulation , vol.115 , pp. 1285-1295
    • Deanfield, J.E.1    Halcox, J.P.2    Rabelink, T.J.3
  • 2
    • 0031019745 scopus 로고    scopus 로고
    • Isolation of putative progenitor endothelial cells for angiogenesis
    • 2 Asahara, T., Murohara, T., Sullivan, A., et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275 (1997), 964–967.
    • (1997) Science , vol.275 , pp. 964-967
    • Asahara, T.1    Murohara, T.2    Sullivan, A.3
  • 3
    • 84857604290 scopus 로고    scopus 로고
    • Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use
    • 3 Fadini, G.P., Losordo, D., Dimmeler, S., Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use. Circ Res 110 (2012), 624–637.
    • (2012) Circ Res , vol.110 , pp. 624-637
    • Fadini, G.P.1    Losordo, D.2    Dimmeler, S.3
  • 4
    • 0034597798 scopus 로고    scopus 로고
    • Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors
    • 4 Yamashita, J., Itoh, H., Hirashima, M., et al. Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature 408 (2000), 92–96.
    • (2000) Nature , vol.408 , pp. 92-96
    • Yamashita, J.1    Itoh, H.2    Hirashima, M.3
  • 5
    • 34548335261 scopus 로고    scopus 로고
    • Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle like cells and form vascular networks in vivo
    • 5 Ferreira, L.S., Gerecht, S., Shieh, H.F., et al. Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle like cells and form vascular networks in vivo. Circ Res 101 (2007), 286–294.
    • (2007) Circ Res , vol.101 , pp. 286-294
    • Ferreira, L.S.1    Gerecht, S.2    Shieh, H.F.3
  • 6
    • 77956696064 scopus 로고    scopus 로고
    • Isolation, differentiation and characterization of vascular cells derived from human embryonic stem cells
    • 6 Levenberg, S., Ferreira, L.S., Chen-Konak, L., Kraehenbuehl, T.P., Langer, R., Isolation, differentiation and characterization of vascular cells derived from human embryonic stem cells. Nat Protoc 5 (2010), 1115–1126.
    • (2010) Nat Protoc , vol.5 , pp. 1115-1126
    • Levenberg, S.1    Ferreira, L.S.2    Chen-Konak, L.3    Kraehenbuehl, T.P.4    Langer, R.5
  • 7
    • 36348969952 scopus 로고    scopus 로고
    • Improvement of postnatal neovascularization by human embryonic stem cell derived endothelial-like cell transplantation in a mouse model of hindlimb ischemia
    • 7 Cho, S.W., Moon, S.H., Lee, S.H., et al. Improvement of postnatal neovascularization by human embryonic stem cell derived endothelial-like cell transplantation in a mouse model of hindlimb ischemia. Circulation 116 (2007), 2409–2419.
    • (2007) Circulation , vol.116 , pp. 2409-2419
    • Cho, S.W.1    Moon, S.H.2    Lee, S.H.3
  • 8
    • 77950557392 scopus 로고    scopus 로고
    • Hypoxia promotes efficient differentiation of human embryonic stem cells to functional endothelium
    • 8 Prado-Lopez, S., Conesa, A., Arminan, A., et al. Hypoxia promotes efficient differentiation of human embryonic stem cells to functional endothelium. Stem Cells 28 (2010), 407–418.
    • (2010) Stem Cells , vol.28 , pp. 407-418
    • Prado-Lopez, S.1    Conesa, A.2    Arminan, A.3
  • 9
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • 9 Takahashi, K., Tanabe, K., Ohnuki, M., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131 (2007), 861–872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 10
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • 10 Takahashi, K., Yamanaka, S., Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126 (2006), 663–676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 11
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • 11 Yu, J., Vodyanik, M.A., Smuga-Otto, K., et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 318 (2007), 1917–1920.
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 12
    • 0034597831 scopus 로고    scopus 로고
    • Developmental biology. One cell, two fates
    • 43, 45
    • 12 Carmeliet, P., Developmental biology. One cell, two fates. Nature, 408, 2000 43, 45.
    • (2000) Nature , vol.408
    • Carmeliet, P.1
  • 13
    • 1842632667 scopus 로고    scopus 로고
    • Endothelial cell-cell junctions: happy together
    • 13 Dejana, E., Endothelial cell-cell junctions: happy together. Nat Rev Mol Cell Biol 5 (2004), 261–270.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 261-270
    • Dejana, E.1
  • 16
    • 34748914299 scopus 로고    scopus 로고
    • Evolving functions of endothelial cells in inflammation
    • 16 Pober, J.S., Sessa, W.C., Evolving functions of endothelial cells in inflammation. Nat Rev Immunol 7 (2007), 803–815.
    • (2007) Nat Rev Immunol , vol.7 , pp. 803-815
    • Pober, J.S.1    Sessa, W.C.2
  • 17
    • 84857766493 scopus 로고    scopus 로고
    • Endothelium – role in regulation of coagulation and inflammation
    • 17 van Hinsbergh, V.W., Endothelium – role in regulation of coagulation and inflammation. Semin Immunopathol 34 (2012), 93–106.
    • (2012) Semin Immunopathol , vol.34 , pp. 93-106
    • van Hinsbergh, V.W.1
  • 18
    • 2642556244 scopus 로고    scopus 로고
    • Endothelial function: a critical determinant in atherosclerosis?
    • 18 Landmesser, U., Hornig, B., Drexler, H., Endothelial function: a critical determinant in atherosclerosis?. Circulation 109:21 suppl 1 (2004), II27–33.
    • (2004) Circulation , vol.109 , Issue.21 , pp. II27-33
    • Landmesser, U.1    Hornig, B.2    Drexler, H.3
  • 20
    • 84866952061 scopus 로고    scopus 로고
    • Arterial endothelial cells: still the craftsmen of regenerated endothelium
    • 20 Hagensen, M.K., Vanhoutte, P.M., Bentzon, J.F., Arterial endothelial cells: still the craftsmen of regenerated endothelium. Cardiovasc Res 95 (2012), 281–289.
    • (2012) Cardiovasc Res , vol.95 , pp. 281-289
    • Hagensen, M.K.1    Vanhoutte, P.M.2    Bentzon, J.F.3
  • 21
    • 84856166753 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells do not contribute to regeneration of endothelium after murine arterial injury
    • 21 Hagensen, M.K., Raarup, M.K., Mortensen, M.B., et al. Circulating endothelial progenitor cells do not contribute to regeneration of endothelium after murine arterial injury. Cardiovasc Res 93 (2012), 223–231.
    • (2012) Cardiovasc Res , vol.93 , pp. 223-231
    • Hagensen, M.K.1    Raarup, M.K.2    Mortensen, M.B.3
  • 22
    • 84856478716 scopus 로고    scopus 로고
    • Endothelial dysfunction as a cellular mechanism for vascular failure
    • 22 Hirase, T., Node, K., Endothelial dysfunction as a cellular mechanism for vascular failure. Am J Physiol Heart Circ Physiol 302 (2012), H499–H505.
    • (2012) Am J Physiol Heart Circ Physiol , vol.302 , pp. H499-H505
    • Hirase, T.1    Node, K.2
  • 23
    • 84862528505 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: past, present, and future
    • 23 Yamanaka, S., Induced pluripotent stem cells: past, present, and future. Cell Stem Cell 10 (2012), 678–684.
    • (2012) Cell Stem Cell , vol.10 , pp. 678-684
    • Yamanaka, S.1
  • 24
    • 65249102249 scopus 로고    scopus 로고
    • Hematopoietic and endothelial differentiation of human induced pluripotent stem cells
    • 24 Choi, K.D., Yu, J., Smuga-Otto, K., et al. Hematopoietic and endothelial differentiation of human induced pluripotent stem cells. Stem Cells 27 (2009), 559–567.
    • (2009) Stem Cells , vol.27 , pp. 559-567
    • Choi, K.D.1    Yu, J.2    Smuga-Otto, K.3
  • 25
    • 67650318728 scopus 로고    scopus 로고
    • Induction and isolation of vascular cells from human induced pluripotent stem cells – brief report
    • 25 Taura, D., Sone, M., Homma, K., et al. Induction and isolation of vascular cells from human induced pluripotent stem cells – brief report. Arterioscler Thromb Vasc Biol 29 (2009), 1100–1103.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1100-1103
    • Taura, D.1    Sone, M.2    Homma, K.3
  • 26
    • 80054932328 scopus 로고    scopus 로고
    • Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease
    • 26 Rufaihah, A.J., Huang, N.F., Jame, S., et al. Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease. Arterioscler Thromb Vasc Biol 31 (2011), e72–79.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. e72-79
    • Rufaihah, A.J.1    Huang, N.F.2    Jame, S.3
  • 27
    • 84868676758 scopus 로고    scopus 로고
    • Endothelial cells derived from nuclear reprogramming
    • 27 Wong, W.T., Huang, N.F., Botham, C.M., Sayed, N., Cooke, J.P., Endothelial cells derived from nuclear reprogramming. Circ Res 111 (2012), 1363–1375.
    • (2012) Circ Res , vol.111 , pp. 1363-1375
    • Wong, W.T.1    Huang, N.F.2    Botham, C.M.3    Sayed, N.4    Cooke, J.P.5
  • 28
    • 84855561934 scopus 로고    scopus 로고
    • Prospects for pluripotent stem cell therapies: into the clinic and back to the bench
    • 28 Grabel, L., Prospects for pluripotent stem cell therapies: into the clinic and back to the bench. J Cell Biochem 113 (2012), 381–387.
    • (2012) J Cell Biochem , vol.113 , pp. 381-387
    • Grabel, L.1
  • 29
    • 79952261648 scopus 로고    scopus 로고
    • Stem cells: the dark side of induced pluripotency
    • 29 Pera, M.F., Stem cells: the dark side of induced pluripotency. Nature 471 (2011), 46–47.
    • (2011) Nature , vol.471 , pp. 46-47
    • Pera, M.F.1
  • 30
    • 53349178722 scopus 로고    scopus 로고
    • In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
    • 30 Zhou, Q., Brown, J., Kanarek, A., Rajagopal, J., Melton, D.A., In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 455 (2008), 627–632.
    • (2008) Nature , vol.455 , pp. 627-632
    • Zhou, Q.1    Brown, J.2    Kanarek, A.3    Rajagopal, J.4    Melton, D.A.5
  • 31
    • 77955321344 scopus 로고    scopus 로고
    • Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
    • 31 Ieda, M., Fu, J.D., Delgado-Olguin, P., et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 142 (2010), 375–386.
    • (2010) Cell , vol.142 , pp. 375-386
    • Ieda, M.1    Fu, J.D.2    Delgado-Olguin, P.3
  • 32
    • 84863629484 scopus 로고    scopus 로고
    • In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
    • 32 Qian, L., Huang, Y., Spencer, C.I., et al. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature 485 (2012), 593–598.
    • (2012) Nature , vol.485 , pp. 593-598
    • Qian, L.1    Huang, Y.2    Spencer, C.I.3
  • 33
    • 77649162059 scopus 로고    scopus 로고
    • Direct conversion of fibroblasts to functional neurons by defined factors
    • 33 Vierbuchen, T., Ostermeier, A., Pang, Z.P., Kokubu, Y., Sudhof, T.C., Wernig, M., Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463 (2010), 1035–1041.
    • (2010) Nature , vol.463 , pp. 1035-1041
    • Vierbuchen, T.1    Ostermeier, A.2    Pang, Z.P.3    Kokubu, Y.4    Sudhof, T.C.5    Wernig, M.6
  • 34
    • 84896142695 scopus 로고    scopus 로고
    • Direct reprogramming of human fibroblasts to functional and expandable hepatocytes
    • 34 Huang, P., Zhang, L., Gao, Y., et al. Direct reprogramming of human fibroblasts to functional and expandable hepatocytes. Cell Stem Cell 14 (2014), 370–384.
    • (2014) Cell Stem Cell , vol.14 , pp. 370-384
    • Huang, P.1    Zhang, L.2    Gao, Y.3
  • 35
    • 79952273710 scopus 로고    scopus 로고
    • Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy
    • 35 Efe, J.A., Hilcove, S., Kim, J., et al. Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat Cell Biol 13 (2011), 215–222.
    • (2011) Nat Cell Biol , vol.13 , pp. 215-222
    • Efe, J.A.1    Hilcove, S.2    Kim, J.3
  • 36
    • 84868138400 scopus 로고    scopus 로고
    • Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFbeta suppression
    • 36 Ginsberg, M., James, D., Ding, B.S., et al. Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFbeta suppression. Cell 151 (2012), 559–575.
    • (2012) Cell , vol.151 , pp. 559-575
    • Ginsberg, M.1    James, D.2    Ding, B.S.3
  • 37
    • 34250214921 scopus 로고    scopus 로고
    • Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis
    • 37 Dejana, E., Taddei, A., Randi, A.M., Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis. Biochim Biophys Acta 1775 (2007), 298–312.
    • (2007) Biochim Biophys Acta , vol.1775 , pp. 298-312
    • Dejana, E.1    Taddei, A.2    Randi, A.M.3
  • 38
    • 84924906922 scopus 로고    scopus 로고
    • Direct conversion of adult skin fibroblasts to endothelial cells by defined factors
    • 38 Han, J.K., Chang, S.H., Cho, H.J., et al. Direct conversion of adult skin fibroblasts to endothelial cells by defined factors. Circulation 130 (2014), 1168–1178.
    • (2014) Circulation , vol.130 , pp. 1168-1178
    • Han, J.K.1    Chang, S.H.2    Cho, H.J.3
  • 39
    • 84920432079 scopus 로고    scopus 로고
    • ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells
    • 39 Morita, R., Suzuki, M., Kasahara, H., et al. ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells. Proc Natl Acad Sci U. S. A 112 (2015), 160–165.
    • (2015) Proc Natl Acad Sci U. S. A , vol.112 , pp. 160-165
    • Morita, R.1    Suzuki, M.2    Kasahara, H.3
  • 41
    • 84871977315 scopus 로고    scopus 로고
    • Conversion of human fibroblasts to angioblast-like progenitor cells
    • 41 Kurian, L., Sancho-Martinez, I., Nivet, E., et al. Conversion of human fibroblasts to angioblast-like progenitor cells. Nat Methods 10 (2013), 77–83.
    • (2013) Nat Methods , vol.10 , pp. 77-83
    • Kurian, L.1    Sancho-Martinez, I.2    Nivet, E.3
  • 42
    • 84865286051 scopus 로고    scopus 로고
    • Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels
    • 42 Margariti, A., Winkler, B., Karamariti, E., et al. Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels. Proc Natl Acad Sci U. S. A 109 (2012), 13793–13798.
    • (2012) Proc Natl Acad Sci U. S. A , vol.109 , pp. 13793-13798
    • Margariti, A.1    Winkler, B.2    Karamariti, E.3
  • 43
    • 84878642797 scopus 로고    scopus 로고
    • Smooth muscle cells differentiated from reprogrammed embryonic lung fibroblasts through DKK3 signaling are potent for tissue engineering of vascular grafts
    • 43 Karamariti, E., Margariti, A., Winkler, B., et al. Smooth muscle cells differentiated from reprogrammed embryonic lung fibroblasts through DKK3 signaling are potent for tissue engineering of vascular grafts. Circ Res 112 (2013), 1433–1443.
    • (2013) Circ Res , vol.112 , pp. 1433-1443
    • Karamariti, E.1    Margariti, A.2    Winkler, B.3
  • 44
    • 84879074469 scopus 로고    scopus 로고
    • Conversion of human fibroblasts to functional endothelial cells by defined factors
    • 44 Li, J., Huang, N.F., Zou, J., et al. Conversion of human fibroblasts to functional endothelial cells by defined factors. Arterioscler Thromb Vasc Biol 33 (2013), 1366–1375.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1366-1375
    • Li, J.1    Huang, N.F.2    Zou, J.3
  • 45
    • 84938324710 scopus 로고    scopus 로고
    • Lineage conversion induced by pluripotency factors involves transient passage through an iPSC stage
    • 45 Bar-Nur, O., Verheul, C., Sommer, A.G., et al. Lineage conversion induced by pluripotency factors involves transient passage through an iPSC stage. Nat Biotechnol 33 (2015), 761–768.
    • (2015) Nat Biotechnol , vol.33 , pp. 761-768
    • Bar-Nur, O.1    Verheul, C.2    Sommer, A.G.3
  • 46
    • 84938400166 scopus 로고    scopus 로고
    • Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors
    • 46 Maza, I., Caspi, I., Zviran, A., et al. Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors. Nat Biotechnol 33 (2015), 769–774.
    • (2015) Nat Biotechnol , vol.33 , pp. 769-774
    • Maza, I.1    Caspi, I.2    Zviran, A.3
  • 47
    • 84924264526 scopus 로고    scopus 로고
    • Direct lineage reprogramming: strategies, mechanisms, and applications
    • 47 Xu, J., Du, Y., Deng, H., Direct lineage reprogramming: strategies, mechanisms, and applications. Cell Stem Cell 16 (2015), 119–134.
    • (2015) Cell Stem Cell , vol.16 , pp. 119-134
    • Xu, J.1    Du, Y.2    Deng, H.3
  • 48
    • 84924906921 scopus 로고    scopus 로고
    • Transdifferentiation of human fibroblasts to endothelial cells: role of innate immunity
    • 48 Sayed, N., Wong, W.T., Ospino, F., et al. Transdifferentiation of human fibroblasts to endothelial cells: role of innate immunity. Circulation 131 (2015), 300–309.
    • (2015) Circulation , vol.131 , pp. 300-309
    • Sayed, N.1    Wong, W.T.2    Ospino, F.3
  • 49
    • 79960417633 scopus 로고    scopus 로고
    • Progenitor cells in arteriosclerosis: good or bad guys?
    • 49 Campagnolo, P., Wong, M.M., Xu, Q., Progenitor cells in arteriosclerosis: good or bad guys?. Antioxid Redox Signal 15 (2011), 1013–1027.
    • (2011) Antioxid Redox Signal , vol.15 , pp. 1013-1027
    • Campagnolo, P.1    Wong, M.M.2    Xu, Q.3
  • 50
    • 77955870523 scopus 로고    scopus 로고
    • Molecular mechanisms of endothelial differentiation
    • 50 Le Bras, A., Vijayaraj, P., Oettgen, P., Molecular mechanisms of endothelial differentiation. Vasc Med 15 (2010), 321–331.
    • (2010) Vasc Med , vol.15 , pp. 321-331
    • Le Bras, A.1    Vijayaraj, P.2    Oettgen, P.3
  • 51
    • 27644435456 scopus 로고    scopus 로고
    • Mechanisms of endothelial differentiation in embryonic vasculogenesis
    • 51 Ferguson, J.E. 3rd, Kelley, R.W., Patterson, C., Mechanisms of endothelial differentiation in embryonic vasculogenesis. Arterioscler Thromb Vasc Biol 25 (2005), 2246–2254.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2246-2254
    • Ferguson, J.E.1    Kelley, R.W.2    Patterson, C.3
  • 52
    • 64249157351 scopus 로고    scopus 로고
    • Epigenetic reprogramming and induced pluripotency
    • 52 Hochedlinger, K., Plath, K., Epigenetic reprogramming and induced pluripotency. Development 136 (2009), 509–523.
    • (2009) Development , vol.136 , pp. 509-523
    • Hochedlinger, K.1    Plath, K.2
  • 53
    • 77956320116 scopus 로고    scopus 로고
    • Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
    • 53 Samavarchi-Tehrani, P., Golipour, A., David, L., et al. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 7 (2010), 64–77.
    • (2010) Cell Stem Cell , vol.7 , pp. 64-77
    • Samavarchi-Tehrani, P.1    Golipour, A.2    David, L.3
  • 54
    • 84870948470 scopus 로고    scopus 로고
    • A late transition in somatic cell reprogramming requires regulators distinct from the pluripotency network
    • 54 Golipour, A., David, L., Liu, Y., et al. A late transition in somatic cell reprogramming requires regulators distinct from the pluripotency network. Cell Stem Cell 11 (2012), 769–782.
    • (2012) Cell Stem Cell , vol.11 , pp. 769-782
    • Golipour, A.1    David, L.2    Liu, Y.3
  • 55
    • 84871586080 scopus 로고    scopus 로고
    • A molecular roadmap of reprogramming somatic cells into iPS cells
    • 55 Polo, J.M., Anderssen, E., Walsh, R.M., et al. A molecular roadmap of reprogramming somatic cells into iPS cells. Cell 151 (2012), 1617–1632.
    • (2012) Cell , vol.151 , pp. 1617-1632
    • Polo, J.M.1    Anderssen, E.2    Walsh, R.M.3
  • 56
    • 84877978530 scopus 로고    scopus 로고
    • Mechanisms and models of somatic cell reprogramming
    • 56 Buganim, Y., Faddah, D.A., Jaenisch, R., Mechanisms and models of somatic cell reprogramming. Nat Rev Genet 14 (2013), 427–439.
    • (2013) Nat Rev Genet , vol.14 , pp. 427-439
    • Buganim, Y.1    Faddah, D.A.2    Jaenisch, R.3
  • 57
    • 84870058502 scopus 로고    scopus 로고
    • Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome
    • 57 Soufi, A., Donahue, G., Zaret, K.S., Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome. Cell 151 (2012), 994–1004.
    • (2012) Cell , vol.151 , pp. 994-1004
    • Soufi, A.1    Donahue, G.2    Zaret, K.S.3
  • 58
    • 79952538234 scopus 로고    scopus 로고
    • Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape
    • 58 Papp, B., Plath, K., Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape. Cell Res 21 (2011), 486–501.
    • (2011) Cell Res , vol.21 , pp. 486-501
    • Papp, B.1    Plath, K.2
  • 59
    • 77958478957 scopus 로고    scopus 로고
    • Kruppel-like factor-4 transcriptionally regulates VE-cadherin expression and endothelial barrier function
    • 59 Cowan, C.E., Kohler, E.E., Dugan, T.A., Mirza, M.K., Malik, A.B., Wary, K.K., Kruppel-like factor-4 transcriptionally regulates VE-cadherin expression and endothelial barrier function. Circ Res 107 (2010), 959–966.
    • (2010) Circ Res , vol.107 , pp. 959-966
    • Cowan, C.E.1    Kohler, E.E.2    Dugan, T.A.3    Mirza, M.K.4    Malik, A.B.5    Wary, K.K.6
  • 60
    • 34250200913 scopus 로고    scopus 로고
    • Kruppel-like factor 4 regulates endothelial inflammation
    • May 4
    • 60 Hamik, A., Lin, Z., Kumar, A., et al. Kruppel-like factor 4 regulates endothelial inflammation. J Biol Chem 282 (May 4 2007), 13769–13779.
    • (2007) J Biol Chem , vol.282 , pp. 13769-13779
    • Hamik, A.1    Lin, Z.2    Kumar, A.3
  • 61
    • 84930442389 scopus 로고    scopus 로고
    • c-Kit+ progenitors generate vascular cells for tissue-engineered grafts through modulation of the Wnt/Klf4 pathway
    • 61 Campagnolo, P., Tsai, T.N., Hong, X., et al. c-Kit+ progenitors generate vascular cells for tissue-engineered grafts through modulation of the Wnt/Klf4 pathway. Biomaterials 60 (2015), 53–61.
    • (2015) Biomaterials , vol.60 , pp. 53-61
    • Campagnolo, P.1    Tsai, T.N.2    Hong, X.3
  • 62
    • 77957551870 scopus 로고    scopus 로고
    • A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
    • 62 Li, R., Liang, J., Ni, S., et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 7 (2010), 51–63.
    • (2010) Cell Stem Cell , vol.7 , pp. 51-63
    • Li, R.1    Liang, J.2    Ni, S.3
  • 63
    • 79955755007 scopus 로고    scopus 로고
    • MicroRNA cluster 302-367 enhances somatic cell reprogramming by accelerating a mesenchymal-to-epithelial transition
    • 63 Liao, B., Bao, X., Liu, L., et al. MicroRNA cluster 302-367 enhances somatic cell reprogramming by accelerating a mesenchymal-to-epithelial transition. J Biol Chem 286 (2011), 17359–17364.
    • (2011) J Biol Chem , vol.286 , pp. 17359-17364
    • Liao, B.1    Bao, X.2    Liu, L.3
  • 64
    • 84871683601 scopus 로고    scopus 로고
    • Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency
    • 64 Hansson, J., Rafiee, M.R., Reiland, S., et al. Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency. Cell Rep 2 (2012), 1579–1592.
    • (2012) Cell Rep , vol.2 , pp. 1579-1592
    • Hansson, J.1    Rafiee, M.R.2    Reiland, S.3
  • 65
    • 84866085864 scopus 로고    scopus 로고
    • Direct reprogramming of fibroblasts into embryonic Sertoli-like cells by defined factors
    • 65 Buganim, Y., Itskovich, E., Hu, Y.C., et al. Direct reprogramming of fibroblasts into embryonic Sertoli-like cells by defined factors. Cell Stem Cell 11 (2012), 373–386.
    • (2012) Cell Stem Cell , vol.11 , pp. 373-386
    • Buganim, Y.1    Itskovich, E.2    Hu, Y.C.3
  • 66
    • 84904580766 scopus 로고    scopus 로고
    • MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures
    • 66 Muraoka, N., Yamakawa, H., Miyamoto, K., et al. MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures. EMBO J 33 (2014), 1565–1581.
    • (2014) EMBO J , vol.33 , pp. 1565-1581
    • Muraoka, N.1    Yamakawa, H.2    Miyamoto, K.3
  • 67
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: a simple pathway becomes complex
    • 67 Bray, S.J., Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 7 (2006), 678–689.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 69
    • 0032235397 scopus 로고    scopus 로고
    • Structural conservation of Notch receptors and ligands
    • 69 Fleming, R.J., Structural conservation of Notch receptors and ligands. Semin Cell Dev Biol 9 (1998), 599–607.
    • (1998) Semin Cell Dev Biol , vol.9 , pp. 599-607
    • Fleming, R.J.1
  • 70
    • 0032897080 scopus 로고    scopus 로고
    • Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1
    • 70 Xue, Y., Gao, X., Lindsell, C.E., et al. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum Mol Genet 8 (1999), 723–730.
    • (1999) Hum Mol Genet , vol.8 , pp. 723-730
    • Xue, Y.1    Gao, X.2    Lindsell, C.E.3
  • 71
    • 0038875342 scopus 로고    scopus 로고
    • Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
    • 71 Li, L., Krantz, I.D., Deng, Y., et al. Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Nat Genet 16 (1997), 243–251.
    • (1997) Nat Genet , vol.16 , pp. 243-251
    • Li, L.1    Krantz, I.D.2    Deng, Y.3
  • 72
    • 0030914459 scopus 로고    scopus 로고
    • Mutations in the human Jagged1 gene are responsible for Alagille syndrome
    • 72 Oda, T., Elkahloun, A.G., Pike, B.L., et al. Mutations in the human Jagged1 gene are responsible for Alagille syndrome. Nat Genet 16 (1997), 235–242.
    • (1997) Nat Genet , vol.16 , pp. 235-242
    • Oda, T.1    Elkahloun, A.G.2    Pike, B.L.3
  • 73
    • 1642271395 scopus 로고    scopus 로고
    • Vascular anomalies in Alagille syndrome: a significant cause of morbidity and mortality
    • 73 Kamath, B.M., Spinner, N.B., Emerick, K.M., et al. Vascular anomalies in Alagille syndrome: a significant cause of morbidity and mortality. Circulation 109 (2004), 1354–1358.
    • (2004) Circulation , vol.109 , pp. 1354-1358
    • Kamath, B.M.1    Spinner, N.B.2    Emerick, K.M.3
  • 74
    • 66449123068 scopus 로고    scopus 로고
    • The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis
    • 74 Benedito, R., Roca, C., Sorensen, I., et al. The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell 137 (2009), 1124–1135.
    • (2009) Cell , vol.137 , pp. 1124-1135
    • Benedito, R.1    Roca, C.2    Sorensen, I.3
  • 75
    • 47649088849 scopus 로고    scopus 로고
    • Specific Jagged-1 signal from bone marrow microenvironment is required for endothelial progenitor cell development for neovascularization
    • 75 Kwon, S.M., Eguchi, M., Wada, M., et al. Specific Jagged-1 signal from bone marrow microenvironment is required for endothelial progenitor cell development for neovascularization. Circulation 118 (2008), 157–165.
    • (2008) Circulation , vol.118 , pp. 157-165
    • Kwon, S.M.1    Eguchi, M.2    Wada, M.3
  • 76
    • 84907300138 scopus 로고    scopus 로고
    • Twist1 induces endothelial differentiation of tumour cells through the Jagged1-KLF4 axis
    • 76 Chen, H.F., Huang, C.H., Liu, C.J., et al. Twist1 induces endothelial differentiation of tumour cells through the Jagged1-KLF4 axis. Nat Commun, 5, 2014, 4697.
    • (2014) Nat Commun , vol.5 , pp. 4697
    • Chen, H.F.1    Huang, C.H.2    Liu, C.J.3
  • 77
    • 84887201460 scopus 로고    scopus 로고
    • Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells
    • 77 Lee, J.B., Werbowetski-Ogilvie, T.E., Lee, J.H., et al. Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells. Blood 122 (2013), 1162–1173.
    • (2013) Blood , vol.122 , pp. 1162-1173
    • Lee, J.B.1    Werbowetski-Ogilvie, T.E.2    Lee, J.H.3
  • 78
    • 0037363922 scopus 로고    scopus 로고
    • HES and HERP families: multiple effectors of the Notch signaling pathway
    • 78 Iso, T., Kedes, L., Hamamori, Y., HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol 194 (2003), 237–255.
    • (2003) J Cell Physiol , vol.194 , pp. 237-255
    • Iso, T.1    Kedes, L.2    Hamamori, Y.3
  • 79
    • 65249185637 scopus 로고    scopus 로고
    • Simvastatin enhances bone marrow stromal cell differentiation into endothelial cells via notch signaling pathway
    • 79 Xu, J., Liu, X., Chen, J., et al. Simvastatin enhances bone marrow stromal cell differentiation into endothelial cells via notch signaling pathway. Am J Physiology Cell Physiol 296 (2009), C535–C543.
    • (2009) Am J Physiology Cell Physiol , vol.296 , pp. C535-C543
    • Xu, J.1    Liu, X.2    Chen, J.3
  • 80
    • 84898419690 scopus 로고    scopus 로고
    • MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1
    • 80 Schober, A., Nazari-Jahantigh, M., Wei, Y., et al. MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1. Nat Med 20 (2014), 368–376.
    • (2014) Nat Med , vol.20 , pp. 368-376
    • Schober, A.1    Nazari-Jahantigh, M.2    Wei, Y.3
  • 81
    • 84880506680 scopus 로고    scopus 로고
    • Adult duct-lining cells can reprogram into beta-like cells able to counter repeated cycles of toxin-induced diabetes
    • 81 Al-Hasani, K., Pfeifer, A., Courtney, M., et al. Adult duct-lining cells can reprogram into beta-like cells able to counter repeated cycles of toxin-induced diabetes. Dev Cell 26 (2013), 86–100.
    • (2013) Dev Cell , vol.26 , pp. 86-100
    • Al-Hasani, K.1    Pfeifer, A.2    Courtney, M.3
  • 82
    • 84892173922 scopus 로고    scopus 로고
    • Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice
    • 82 Baeyens, L., Lemper, M., Leuckx, G., et al. Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice. Nat Biotechnol 32 (2014), 76–83.
    • (2014) Nat Biotechnol , vol.32 , pp. 76-83
    • Baeyens, L.1    Lemper, M.2    Leuckx, G.3
  • 83
    • 84877265318 scopus 로고    scopus 로고
    • Cell therapy of peripheral arterial disease: from experimental findings to clinical trials
    • 83 Raval, Z., Losordo, D.W., Cell therapy of peripheral arterial disease: from experimental findings to clinical trials. Circ Res 112 (2013), 1288–1302.
    • (2013) Circ Res , vol.112 , pp. 1288-1302
    • Raval, Z.1    Losordo, D.W.2
  • 84
    • 84881114106 scopus 로고    scopus 로고
    • Therapeutic angiogenesis for critical limb ischaemia
    • 84 Annex, B.H., Therapeutic angiogenesis for critical limb ischaemia. Nat Rev Cardiol 10 (2013), 387–396.
    • (2013) Nat Rev Cardiol , vol.10 , pp. 387-396
    • Annex, B.H.1
  • 85
    • 84864874302 scopus 로고    scopus 로고
    • Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
    • 85 Lippmann, E.S., Azarin, S.M., Kay, J.E., et al. Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells. Nat Biotechnol 30 (2012), 783–791.
    • (2012) Nat Biotechnol , vol.30 , pp. 783-791
    • Lippmann, E.S.1    Azarin, S.M.2    Kay, J.E.3
  • 86
    • 84880948836 scopus 로고    scopus 로고
    • Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration
    • 86 Nolan, D.J., Ginsberg, M., Israely, E., et al. Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration. Dev Cell 26 (2013), 204–219.
    • (2013) Dev Cell , vol.26 , pp. 204-219
    • Nolan, D.J.1    Ginsberg, M.2    Israely, E.3
  • 87
    • 84941253569 scopus 로고    scopus 로고
    • Generation and grafting of tissue-engineered vessels in a mouse model
    • 87 Wong, M.M., Hong, X., Karamariti, E., Hu, Y., Xu, Q., Generation and grafting of tissue-engineered vessels in a mouse model. J Vis Exp, 2015, e52565, 10.3791/52565 (2015).
    • (2015) J Vis Exp , pp. e52565
    • Wong, M.M.1    Hong, X.2    Karamariti, E.3    Hu, Y.4    Xu, Q.5
  • 88
    • 84907007919 scopus 로고    scopus 로고
    • A selective microRNA-based strategy inhibits restenosis while preserving endothelial function
    • 88 Santulli, G., Wronska, A., Uryu, K., et al. A selective microRNA-based strategy inhibits restenosis while preserving endothelial function. J Clin Invest 124 (2014), 4102–4114.
    • (2014) J Clin Invest , vol.124 , pp. 4102-4114
    • Santulli, G.1    Wronska, A.2    Uryu, K.3
  • 89
    • 84908431507 scopus 로고    scopus 로고
    • Dissecting engineered cell types and enhancing cell fate conversion via CellNet
    • 89 Morris, S.A., Cahan, P., Li, H., et al. Dissecting engineered cell types and enhancing cell fate conversion via CellNet. Cell 158 (2014), 889–902.
    • (2014) Cell , vol.158 , pp. 889-902
    • Morris, S.A.1    Cahan, P.2    Li, H.3
  • 90
    • 84959344588 scopus 로고    scopus 로고
    • A predictive computational framework for direct reprogramming between human cell types
    • 90 Rackham, O.J., Firas, J., Fang, H., et al. A predictive computational framework for direct reprogramming between human cell types. Nat Genet 48 (2016), 331–335.
    • (2016) Nat Genet , vol.48 , pp. 331-335
    • Rackham, O.J.1    Firas, J.2    Fang, H.3
  • 91
    • 84946716550 scopus 로고    scopus 로고
    • A systematic approach to identify candidate transcription factors that control cell identity
    • 91 D'Alessio, A.C., Fan, Z.P., Wert, K.J., et al. A systematic approach to identify candidate transcription factors that control cell identity. Stem Cell Rep 5 (2015), 763–775.
    • (2015) Stem Cell Rep , vol.5 , pp. 763-775
    • D'Alessio, A.C.1    Fan, Z.P.2    Wert, K.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.