Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells

Blood

Volumn 122, Issue 7, 2013, Pages 1162-1173

  Lee, Jung Bok ^a,b   Werbowetski Ogilvie, Tamra E ^a,b   Lee, Jong Hee ^a,b   McIntyre, Brendan A S ^a,b   Schnerch, Angelique ^a,b   Hong, Seok Ho ^a,b   Park, In Hyun ^c,d,e,f   Daley, George Q ^c,d,e,f   Bernstein, Irwin D ^g   Bhatia, Mickie ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f HARVARD STEM CELL INSTITUTE   (United States)

^g Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH RECEPTOR; TRANSCRIPTION FACTOR HES 1; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BIOLOGICAL MARKER; HES1 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; NOTCH1 PROTEIN, HUMAN; NOTCH1 RECEPTOR; SMALL INTERFERING RNA;

ADULT; ARTICLE; CELL FATE; CELL LINEAGE; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; GAIN OF FUNCTION MUTATION; HEMATOPOIESIS; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HUMAN EMBRYONIC STEM CELL; INDUCED PLURIPOTENT STEM CELL; LOSS OF FUNCTION MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; APOPTOSIS; CELL CULTURE; CELL DIFFERENTIATION; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; DERMIS; DNA MICROARRAY; DRUG ANTAGONISM; EMBRYONIC STEM CELL; ENZYME IMMUNOASSAY; FIBROBLAST; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HEMATOPOIETIC STEM CELL; METABOLISM; PHYSIOLOGY; PLURIPOTENT STEM CELL; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

APOPTOSIS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DERMIS; EMBRYONIC STEM CELLS; ENDOTHELIUM, VASCULAR; FIBROBLASTS; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOENZYME TECHNIQUES; INDUCED PLURIPOTENT STEM CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTOR, NOTCH1; RECEPTORS, NOTCH; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84887201460     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-12-471649     Document Type: Article

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