Peripheral blood mitochondrial DNA damage as a potential noninvasive biomarker of diabetic retinopathy

Investigative Ophthalmology and Visual Science

Volumn 57, Issue 10, 2016, Pages 4035-4044

  Mishra, Manish ^a   Lillvis, John ^a   Seyoum, Berhane ^a   Kowluru, Renu A ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

Biomarker; Diabetic retinopathy; DNA damage; Mitochondria

Indexed keywords

BETA ACTIN; BIOLOGICAL MARKER; CYTOCHROME B; GELATINASE B; GLUCOSE; HEMOGLOBIN A1C; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; THIOCTIC ACID;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; DIABETIC RETINOPATHY; DNA DAMAGE; DNA TRANSCRIPTION; GENE OVEREXPRESSION; GLYCEMIC CONTROL; HISTOPATHOLOGY; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MIDDLE AGED; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ANIMAL; BLOOD; C57BL MOUSE; COMPLICATION; DIABETES MELLITUS; EXPERIMENTAL DIABETES MELLITUS; FEMALE; GENETICS; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; PATHOLOGY; RETINA; ZUCKER RAT;

ADULT; AGED; ANIMALS; BIOMARKERS; DIABETES MELLITUS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; DNA DAMAGE; DNA, MITOCHONDRIAL; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; MITOCHONDRIA; POLYMERASE CHAIN REACTION; RATS; RATS, ZUCKER; RETINA;

EID: 84983057048     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.16-19073     Document Type: Article

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