Blood cells from Friedreich ataxia patients harbor frataxin deficiency without a loss of mitochondrial function

Mitochondrion

Volumn 11, Issue 2, 2011, Pages 342-350

  Selak, Mary A ^a   Lyver, Elise ^b   Micklow, Elizabeth ^b   Deutsch, Eric C ^b   Önder, Özlem ^c   Selamoglu, Nur ^c   Yager, Claire ^a   Knight, Simon ^b   Carroll, Martin ^b   Daldal, Fevzi ^c   Dancis, Andrew ^b   Lynch, David R ^b   Sarry, Jean Emmanuel ^b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Biomarkers; Blood cells; Frataxin; Friedreich ataxia; Mitochondria

Indexed keywords

FRATAXIN; HEAT SHOCK PROTEIN; MITOCHONDRIAL PROTEIN;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CELL FUNCTION; CELL LEVEL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FRIEDREICH ATAXIA; FUNCTIONAL PROTEOMICS; GENE SEQUENCE; HUMAN; HUMAN CELL; MALE; MITOCHONDRIAL RESPIRATION; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN TARGETING;

ADULT; BLOTTING, WESTERN; CASE-CONTROL STUDIES; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; FRIEDREICH ATAXIA; HUMANS; IRON-BINDING PROTEINS; MALE; MASS SPECTROMETRY; MITOCHONDRIA;

EID: 79251600162     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2010.12.003     Document Type: Article

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