Retinal mitochondrial DNA mismatch repair in the development of diabetic retinopathy, and its continued progression after termination of hyperglycemia

Investigative ophthalmology & visual science

Volumn 55, Issue 10, 2014, Pages 6960-6967

  Mishra, Manish ^a   Kowluru, Renu A ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

diabetic retinopathy; DNA repair; metabolic memory; mitochondria damage; mtDNA mismatch

Indexed keywords

MITOCHONDRIAL DNA; MSH2 PROTEIN, RAT; PROTEIN MSH2;

ANIMAL; BIOSYNTHESIS; BOVINE; DIABETIC RETINOPATHY; DISEASE COURSE; DNA DAMAGE; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; HYPERGLYCEMIA; MALE; METABOLISM; MISMATCH REPAIR; MITOCHONDRION; PATHOLOGY; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA; VASCULAR ENDOTHELIUM; WISTAR RAT;

ANIMALS; CATTLE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; DISEASE PROGRESSION; DNA DAMAGE; DNA MISMATCH REPAIR; DNA, MITOCHONDRIAL; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HYPERGLYCEMIA; MALE; MITOCHONDRIA; MUTS HOMOLOG 2 PROTEIN; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RETINA;

EID: 84922330317     PISSN: None     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.14-15020     Document Type: Article

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