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Volumn 76, Issue , 2016, Pages 25-32

Muscle function and fat content in relation to sarcopenia, obesity and frailty of old age — An overview

Author keywords

Fat mass; Frailty; Muscle function; Muscle mass; Obese frail; Sarcopenia; Sarcopenic obese

Indexed keywords

AGING; BIOACCUMULATION; DYNAPENIA; FAT CONTENT; FRAIL ELDERLY; FUNCTIONAL DISEASE; HUMAN; INSULIN RESISTANCE; LIPID STORAGE; MUSCLE FUNCTION; MUSCLE MASS; MUSCLE STRENGTH; MUSCLE WEAKNESS; NONHUMAN; OBESITY; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SARCOPENIA; AGE; AGED; COMPLICATION; ENERGY METABOLISM; GERIATRIC ASSESSMENT; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHENOTYPE; SKELETAL MUSCLE;

EID: 84983049677     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2016.01.008     Document Type: Review
Times cited : (151)

References (75)
  • 2
    • 84893197194 scopus 로고    scopus 로고
    • Intermuscular fat: a review of the consequences and causes
    • ([Internet], [cited 2015 Apr 5]; 2014)
    • Addison, O., Marcus, R.L., LaStayo, P.C., Ryan, A.S., Intermuscular fat: a review of the consequences and causes. Int. J. Endocrinol., 2014 ([Internet], [cited 2015 Apr 5]; 2014).
    • (2014) Int. J. Endocrinol.
    • Addison, O.1    Marcus, R.L.2    LaStayo, P.C.3    Ryan, A.S.4
  • 3
    • 62149122567 scopus 로고    scopus 로고
    • Life course social and health conditions linked to frailty in Latin American older men and women
    • (Dec 1)
    • Alvarado, B.E., Zunzunegui, M.-V., Béland, F., Bamvita, J.-M., Life course social and health conditions linked to frailty in Latin American older men and women. J. Gerontol. A Biol. Sci. Med. Sci. 63:12 (2008), 1399–1406 (Dec 1).
    • (2008) J. Gerontol. A Biol. Sci. Med. Sci. , vol.63 , Issue.12 , pp. 1399-1406
    • Alvarado, B.E.1    Zunzunegui, M.-V.2    Béland, F.3    Bamvita, J.-M.4
  • 4
    • 84930090368 scopus 로고    scopus 로고
    • Japan as the front-runner of super-aged societies: perspectives from medicine and medical care in Japan
    • (Jun 1)
    • Arai, H., Ouchi, Y., Toba, K., Endo, T., Shimokado, K., Tsubota, K., et al. Japan as the front-runner of super-aged societies: perspectives from medicine and medical care in Japan. Geriatr. Gerontol. Int. 15:6 (2015), 673–687 (Jun 1).
    • (2015) Geriatr. Gerontol. Int. , vol.15 , Issue.6 , pp. 673-687
    • Arai, H.1    Ouchi, Y.2    Toba, K.3    Endo, T.4    Shimokado, K.5    Tsubota, K.6
  • 5
    • 34248141686 scopus 로고    scopus 로고
    • Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients
    • (May)
    • Befroy, D.E., Petersen, K.F., Dufour, S., Mason, G.F., de Graaf, R.A., Rothman, D.L., et al. Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients. Diabetes 56:5 (2007), 1376–1381 (May).
    • (2007) Diabetes , vol.56 , Issue.5 , pp. 1376-1381
    • Befroy, D.E.1    Petersen, K.F.2    Dufour, S.3    Mason, G.F.4    de Graaf, R.A.5    Rothman, D.L.6
  • 6
    • 23444450084 scopus 로고    scopus 로고
    • The association between obesity and the frailty syndrome in older women: the Women's Health and Aging Studies
    • (Jun 1)
    • Blaum, C.S., Xue, Q.L., Michelon, E., Semba, R.D., Fried, L.P., The association between obesity and the frailty syndrome in older women: the Women's Health and Aging Studies. J. Am. Geriatr. Soc. 53:6 (2005), 927–934 (Jun 1).
    • (2005) J. Am. Geriatr. Soc. , vol.53 , Issue.6 , pp. 927-934
    • Blaum, C.S.1    Xue, Q.L.2    Michelon, E.3    Semba, R.D.4    Fried, L.P.5
  • 7
    • 70350569878 scopus 로고    scopus 로고
    • Sarcopenic/obesity and physical capacity in older men and women: data from the Nutrition as a Determinant of Successful Aging (NuAge)—the Quebec longitudinal Study
    • (Nov)
    • Bouchard, D.R., Dionne, I.J., Brochu, M., Sarcopenic/obesity and physical capacity in older men and women: data from the Nutrition as a Determinant of Successful Aging (NuAge)—the Quebec longitudinal Study. Obesity (Silver Spring) 17:11 (2009), 2082–2088 (Nov).
    • (2009) Obesity (Silver Spring) , vol.17 , Issue.11 , pp. 2082-2088
    • Bouchard, D.R.1    Dionne, I.J.2    Brochu, M.3
  • 8
    • 84904195059 scopus 로고    scopus 로고
    • Endocrine crosstalk between muscle and bone
    • (Jun)
    • Brotto, M., Johnson, M.L., Endocrine crosstalk between muscle and bone. Curr. Osteoporos. Rep. 12:2 (2014), 135–141 (Jun).
    • (2014) Curr. Osteoporos. Rep. , vol.12 , Issue.2 , pp. 135-141
    • Brotto, M.1    Johnson, M.L.2
  • 9
    • 34248550944 scopus 로고    scopus 로고
    • Aging in adipocytes: potential impact of inherent, depot-specific mechanisms
    • (Jun)
    • Cartwright, M.J., Tchkonia, T., Kirkland, J.L., Aging in adipocytes: potential impact of inherent, depot-specific mechanisms. Exp Gerontol. 42:6 (2007), 463–471 (Jun).
    • (2007) Exp Gerontol. , vol.42 , Issue.6 , pp. 463-471
    • Cartwright, M.J.1    Tchkonia, T.2    Kirkland, J.L.3
  • 10
    • 84880107904 scopus 로고    scopus 로고
    • Relationship between muscle mass and muscle strength, and the impact of comorbidities: a population-based, cross-sectional study of older adults in the United States
    • (Jul 16)
    • Chen, L., Nelson, D.R., Zhao, Y., Cui, Z., Johnston, J.A., Relationship between muscle mass and muscle strength, and the impact of comorbidities: a population-based, cross-sectional study of older adults in the United States. BMC Geriatr., 13, 2013, 74 (Jul 16).
    • (2013) BMC Geriatr. , vol.13 , pp. 74
    • Chen, L.1    Nelson, D.R.2    Zhao, Y.3    Cui, Z.4    Johnston, J.A.5
  • 11
    • 84869495015 scopus 로고    scopus 로고
    • Body composition and its association with cardiometabolic risk factors in the elderly: a focus on sarcopenic obesity
    • (Feb)
    • Chung, J.-Y., Kang, H.-T., Lee, D.-C., Lee, H.-R., Lee, Y.-J., Body composition and its association with cardiometabolic risk factors in the elderly: a focus on sarcopenic obesity. Arch. Gerontol. Geriatr. 56:1 (2013), 270–278 (Feb).
    • (2013) Arch. Gerontol. Geriatr. , vol.56 , Issue.1 , pp. 270-278
    • Chung, J.-Y.1    Kang, H.-T.2    Lee, D.-C.3    Lee, H.-R.4    Lee, Y.-J.5
  • 13
    • 84859172431 scopus 로고    scopus 로고
    • What is dynapenia?
    • (May)
    • Clark, B.C., Manini, T.M., What is dynapenia?. Nutrition 28:5 (2012), 495–503 (May).
    • (2012) Nutrition , vol.28 , Issue.5 , pp. 495-503
    • Clark, B.C.1    Manini, T.M.2
  • 15
    • 84883294068 scopus 로고    scopus 로고
    • Interleukin-6 and obesity: the crosstalk between intestine, pancreas and liver
    • (Aug)
    • El-Kadre, L.J., Tinoco, A.C.A., Interleukin-6 and obesity: the crosstalk between intestine, pancreas and liver. Curr. Opin. Clin. Nutr. Metab. Care, 1, 2013 (Aug).
    • (2013) Curr. Opin. Clin. Nutr. Metab. Care , vol.1
    • El-Kadre, L.J.1    Tinoco, A.C.A.2
  • 16
    • 0035032163 scopus 로고    scopus 로고
    • Overexpressing human lipoprotein lipase in mouse skeletal muscle is associated with insulin resistance
    • (May 1)
    • Ferreira, L.D.M.C.-B., Pulawa, L.K., Jensen, D.R., Eckel, R.H., Overexpressing human lipoprotein lipase in mouse skeletal muscle is associated with insulin resistance. Diabetes 50:5 (2001), 1064–1068 (May 1).
    • (2001) Diabetes , vol.50 , Issue.5 , pp. 1064-1068
    • Ferreira, L.D.M.C.-B.1    Pulawa, L.K.2    Jensen, D.R.3    Eckel, R.H.4
  • 17
    • 1842784019 scopus 로고    scopus 로고
    • Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus report
    • (Apr 1)
    • Ferrucci, L., Guralnik, J.M., Studenski, S., Fried, L.P., Cutler, G.B., Walston, J.D., et al. Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus report. J. Am. Geriatr. Soc. 52:4 (2004), 625–634 (Apr 1).
    • (2004) J. Am. Geriatr. Soc. , vol.52 , Issue.4 , pp. 625-634
    • Ferrucci, L.1    Guralnik, J.M.2    Studenski, S.3    Fried, L.P.4    Cutler, G.B.5    Walston, J.D.6
  • 18
    • 79951558318 scopus 로고    scopus 로고
    • National, regional, and global trends in body mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants
    • (Feb 12)
    • Finucane, M.M., Stevens, G.A., Cowan, M., Danaei, G., Lin, J.K., Paciorek, C.J., et al. National, regional, and global trends in body mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants. Lancet 377:9765 (2011), 557–567 (Feb 12).
    • (2011) Lancet , vol.377 , Issue.9765 , pp. 557-567
    • Finucane, M.M.1    Stevens, G.A.2    Cowan, M.3    Danaei, G.4    Lin, J.K.5    Paciorek, C.J.6
  • 20
    • 84929646308 scopus 로고    scopus 로고
    • Irisin and myonectin regulation in the insulin resistant muscle: implications to adipose tissue: muscle crosstalk
    • ([Internet], [cited 2015 Nov 1];2015)
    • Gamas, L., Matafome, P., Seiça, R., Irisin and myonectin regulation in the insulin resistant muscle: implications to adipose tissue: muscle crosstalk. J. Diabetes Res., 2015 ([Internet], [cited 2015 Nov 1];2015).
    • (2015) J. Diabetes Res.
    • Gamas, L.1    Matafome, P.2    Seiça, R.3
  • 21
    • 0042810882 scopus 로고    scopus 로고
    • Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and women
    • (Feb 1)
    • Goodpaster, B.H., Krishnaswami, S., Resnick, H., Kelley, D.E., Haggerty, C., Harris, T.B., et al. Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and women. Diabetes Care 26:2 (2003), 372–379 (Feb 1).
    • (2003) Diabetes Care , vol.26 , Issue.2 , pp. 372-379
    • Goodpaster, B.H.1    Krishnaswami, S.2    Resnick, H.3    Kelley, D.E.4    Haggerty, C.5    Harris, T.B.6
  • 22
    • 33750927350 scopus 로고    scopus 로고
    • The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study
    • (Oct 1)
    • Goodpaster, B.H., Park, S.W., Harris, T.B., Kritchevsky, S.B., Nevitt, M., Schwartz, A.V., et al. The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. J. Gerontol. A Biol. Sci. Med. Sci. 61:10 (2006), 1059–1064 (Oct 1).
    • (2006) J. Gerontol. A Biol. Sci. Med. Sci. , vol.61 , Issue.10 , pp. 1059-1064
    • Goodpaster, B.H.1    Park, S.W.2    Harris, T.B.3    Kritchevsky, S.B.4    Nevitt, M.5    Schwartz, A.V.6
  • 23
    • 57349155568 scopus 로고    scopus 로고
    • Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial
    • Nov)
    • Goodpaster, B.H., Chomentowski, P., Ward, B.K., Rossi, A., Glynn, N.W., Delmonico, M.J., et al. Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial. J. Appl. Physiol. 105:5 (2008), 1498–1503 Nov).
    • (2008) J. Appl. Physiol. , vol.105 , Issue.5 , pp. 1498-1503
    • Goodpaster, B.H.1    Chomentowski, P.2    Ward, B.K.3    Rossi, A.4    Glynn, N.W.5    Delmonico, M.J.6
  • 24
    • 33646934768 scopus 로고    scopus 로고
    • Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes
    • (Apr 7)
    • Gustafson, B., Smith, U., Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes. J. Biol. Chem. 281:14 (2006), 9507–9516 (Apr 7).
    • (2006) J. Biol. Chem. , vol.281 , Issue.14 , pp. 9507-9516
    • Gustafson, B.1    Smith, U.2
  • 25
    • 8844235609 scopus 로고    scopus 로고
    • A 24-year follow-up of body mass index and cerebral atrophy
    • (Nov 23)
    • Gustafson, D., Lissner, L., Bengtsson, C., Bjorkelund, C., Skoog, I., A 24-year follow-up of body mass index and cerebral atrophy. Neurology 63:10 (2004), 1876–1881 (Nov 23).
    • (2004) Neurology , vol.63 , Issue.10 , pp. 1876-1881
    • Gustafson, D.1    Lissner, L.2    Bengtsson, C.3    Bjorkelund, C.4    Skoog, I.5
  • 26
    • 7444240744 scopus 로고    scopus 로고
    • Body mass index and white matter lesions in elderly women. An 18-year longitudinal study
    • (Sep)
    • Gustafson, D.R., Steen, B., Skoog, I., Body mass index and white matter lesions in elderly women. An 18-year longitudinal study. Int. Psychogeriatr. 16:03 (2004), 327–336 (Sep).
    • (2004) Int. Psychogeriatr. , vol.16 , Issue.3 , pp. 327-336
    • Gustafson, D.R.1    Steen, B.2    Skoog, I.3
  • 27
    • 84874279236 scopus 로고    scopus 로고
    • Body mass index, muscle strength and physical performance in older adults from eight cohort studies: the HALCyon programme
    • Hardy, R., Cooper, R., Aihie Sayer, A., Ben-Shlomo, Y., Cooper, C., Deary, I.J., et al. Body mass index, muscle strength and physical performance in older adults from eight cohort studies: the HALCyon programme. PLoS ONE, 8(2), 2013, e56483.
    • (2013) PLoS ONE , vol.8 , Issue.2
    • Hardy, R.1    Cooper, R.2    Aihie Sayer, A.3    Ben-Shlomo, Y.4    Cooper, C.5    Deary, I.J.6
  • 29
    • 0035037572 scopus 로고    scopus 로고
    • Longitudinal muscle strength changes in older adults influence of muscle mass, physical activity, and health
    • (May 1)
    • Hughes, V.A., Frontera, W.R., Wood, M., Evans, W.J., Dallal, G.E., Roubenoff, R., et al. Longitudinal muscle strength changes in older adults influence of muscle mass, physical activity, and health. J. Gerontol. A Biol. Sci. Med. Sci. 56:5 (2001), B209–B217 (May 1).
    • (2001) J. Gerontol. A Biol. Sci. Med. Sci. , vol.56 , Issue.5 , pp. B209-B217
    • Hughes, V.A.1    Frontera, W.R.2    Wood, M.3    Evans, W.J.4    Dallal, G.E.5    Roubenoff, R.6
  • 30
    • 33645141176 scopus 로고    scopus 로고
    • Influence of sarcopenia on the development of physical disability: the Cardiovascular Health Study
    • Janssen, I., Influence of sarcopenia on the development of physical disability: the Cardiovascular Health Study. J. Am. Geriatr. Soc. 54:1 (2006), 56–62.
    • (2006) J. Am. Geriatr. Soc. , vol.54 , Issue.1 , pp. 56-62
    • Janssen, I.1
  • 31
    • 79961071833 scopus 로고    scopus 로고
    • The epidemiology of sarcopenia
    • (Aug)
    • Janssen, I., The epidemiology of sarcopenia. Clin. Geriatr. Med. 27:3 (2011), 355–363 (Aug).
    • (2011) Clin. Geriatr. Med. , vol.27 , Issue.3 , pp. 355-363
    • Janssen, I.1
  • 32
    • 0036246979 scopus 로고    scopus 로고
    • Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability
    • Janssen, I., Heymsfield, S.B., Ross, R., Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J. Am. Geriatr. Soc. 50:5 (2002), 889–896.
    • (2002) J. Am. Geriatr. Soc. , vol.50 , Issue.5 , pp. 889-896
    • Janssen, I.1    Heymsfield, S.B.2    Ross, R.3
  • 33
    • 84929452481 scopus 로고    scopus 로고
    • Sarcopenia — the search for emerging biomarkers
    • (Jul)
    • Kalinkovich, A., Livshits, G., Sarcopenia — the search for emerging biomarkers. Ageing Res. Rev. 22 (2015), 58–71 (Jul).
    • (2015) Ageing Res. Rev. , vol.22 , pp. 58-71
    • Kalinkovich, A.1    Livshits, G.2
  • 34
    • 0025300784 scopus 로고
    • The role of muscle loss in the age-related decline of grip strength: cross-sectional and longitudinal perspectives
    • (May 1)
    • Kallman, D.A., Plato, C.C., Tobin, J.D., The role of muscle loss in the age-related decline of grip strength: cross-sectional and longitudinal perspectives. J. Gerontol. 45:3 (1990), M82–M88 (May 1).
    • (1990) J. Gerontol. , vol.45 , Issue.3 , pp. M82-M88
    • Kallman, D.A.1    Plato, C.C.2    Tobin, J.D.3
  • 35
    • 0035912744 scopus 로고    scopus 로고
    • Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
    • (Jun 19)
    • Kim, J.K., Fillmore, J.J., Chen, Y., Yu, C., Moore, I.K., Pypaert, M., et al. Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc. Natl. Acad. Sci. U. S. A. 98:13 (2001), 7522–7527 (Jun 19).
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.13 , pp. 7522-7527
    • Kim, J.K.1    Fillmore, J.J.2    Chen, Y.3    Yu, C.4    Moore, I.K.5    Pypaert, M.6
  • 36
    • 68949159838 scopus 로고    scopus 로고
    • Prevalence of sarcopenia and sarcopenic obesity in Korean adults: the Korean sarcopenic obesity study
    • (2009 Aug)
    • Kim, T.N., Yang, S.J., Yoo, H.J., Lim, K.I., Kang, H.J., Song, W., et al. Prevalence of sarcopenia and sarcopenic obesity in Korean adults: the Korean sarcopenic obesity study. Int. J. Obes. 33:8 (2005), 885–892 (2009 Aug).
    • (2005) Int. J. Obes. , vol.33 , Issue.8 , pp. 885-892
    • Kim, T.N.1    Yang, S.J.2    Yoo, H.J.3    Lim, K.I.4    Kang, H.J.5    Song, W.6
  • 37
    • 77958170721 scopus 로고    scopus 로고
    • Prevalence and determinant factors of sarcopenia in patients with type 2 diabetes: the Korean Sarcopenic Obesity Study (KSOS)
    • (Jul)
    • Kim, T.N., Park, M.S., Yang, S.J., Yoo, H.J., Kang, H.J., Song, W., et al. Prevalence and determinant factors of sarcopenia in patients with type 2 diabetes: the Korean Sarcopenic Obesity Study (KSOS). Diabetes Care 33:7 (2010), 1497–1499 (Jul).
    • (2010) Diabetes Care , vol.33 , Issue.7 , pp. 1497-1499
    • Kim, T.N.1    Park, M.S.2    Yang, S.J.3    Yoo, H.J.4    Kang, H.J.5    Song, W.6
  • 38
    • 84919341210 scopus 로고    scopus 로고
    • Impact of visceral fat on skeletal muscle mass and vice versa in a prospective cohort study: the Korean Sarcopenic Obesity Study (KSOS)
    • (Dec 17). ([Internet], [cited 2015 Apr 5])
    • Kim, T.N., Park, M.S., Ryu, J.Y., Choi, H.Y., Hong, H.C., Yoo, H.J., et al. Impact of visceral fat on skeletal muscle mass and vice versa in a prospective cohort study: the Korean Sarcopenic Obesity Study (KSOS). PLoS ONE, 9(12), 2014 (Dec 17). ([Internet], [cited 2015 Apr 5]).
    • (2014) PLoS ONE , vol.9 , Issue.12
    • Kim, T.N.1    Park, M.S.2    Ryu, J.Y.3    Choi, H.Y.4    Hong, H.C.5    Yoo, H.J.6
  • 39
    • 33846994715 scopus 로고    scopus 로고
    • Understanding frailty
    • (Jan)
    • Lally, F., Crome, P., Understanding frailty. Postgrad. Med. J. 83:975 (2007), 16–20 (Jan).
    • (2007) Postgrad. Med. J. , vol.83 , Issue.975 , pp. 16-20
    • Lally, F.1    Crome, P.2
  • 41
    • 70349493058 scopus 로고    scopus 로고
    • Frailty syndrome: a transitional state in a dynamic process
    • Lang, P.-O., Michel, J.-P., Zekry, D., Frailty syndrome: a transitional state in a dynamic process. Gerontology 55:5 (2009), 539–549.
    • (2009) Gerontology , vol.55 , Issue.5 , pp. 539-549
    • Lang, P.-O.1    Michel, J.-P.2    Zekry, D.3
  • 42
    • 77950959542 scopus 로고    scopus 로고
    • Sarcopenia: etiology, clinical consequences, intervention, and assessment
    • (Apr)
    • Lang, T., Streeper, T., Cawthon, P., Baldwin, K., Taaffe, D.R., Harris, T.B., Sarcopenia: etiology, clinical consequences, intervention, and assessment. Osteoporos. Int. 21:4 (2010), 543–559 (Apr).
    • (2010) Osteoporos. Int. , vol.21 , Issue.4 , pp. 543-559
    • Lang, T.1    Streeper, T.2    Cawthon, P.3    Baldwin, K.4    Taaffe, D.R.5    Harris, T.B.6
  • 43
    • 84862290998 scopus 로고    scopus 로고
    • Sarcopenic obesity and cognitive functioning: the mediating roles of insulin resistance and inflammation?
    • ([Internet], [cited 2015 Apr 5];2012)
    • Levine, M.E., Crimmins, E.M., Sarcopenic obesity and cognitive functioning: the mediating roles of insulin resistance and inflammation?. Curr. Gerontol. Geriatr. Res., 2012 ([Internet], [cited 2015 Apr 5];2012).
    • (2012) Curr. Gerontol. Geriatr. Res.
    • Levine, M.E.1    Crimmins, E.M.2
  • 44
    • 77958170959 scopus 로고    scopus 로고
    • Sarcopenic obesity: prevalence and association with metabolic syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA)
    • (Jul)
    • Lim, S., Kim, J.H., Yoon, J.W., Kang, S.M., Choi, S.H., Park, Y.J., et al. Sarcopenic obesity: prevalence and association with metabolic syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA). Diabetes Care 33:7 (2010), 1652–1654 (Jul).
    • (2010) Diabetes Care , vol.33 , Issue.7 , pp. 1652-1654
    • Lim, S.1    Kim, J.H.2    Yoon, J.W.3    Kang, S.M.4    Choi, S.H.5    Park, Y.J.6
  • 45
    • 84927171563 scopus 로고    scopus 로고
    • Roles of chronic low-grade inflammation in the development of ectopic fat deposition
    • ([Internet], [cited 2015 Apr 1];2014)
    • Liu, L., Mei, M., Yang, S., Li, Q., Roles of chronic low-grade inflammation in the development of ectopic fat deposition. Mediat. Inflamm., 2014 ([Internet], [cited 2015 Apr 1];2014).
    • (2014) Mediat. Inflamm.
    • Liu, L.1    Mei, M.2    Yang, S.3    Li, Q.4
  • 47
    • 84866628227 scopus 로고    scopus 로고
    • Intramuscular adipose tissue, sarcopenia, and mobility function in older individuals
    • ([Internet], [cited 2015 Feb 5]; 2012)
    • Marcus, R.L., Addison, O., Dibble, L.E., Foreman, K.B., Morrell, G., LaStayo, P., Intramuscular adipose tissue, sarcopenia, and mobility function in older individuals. J. Aging Res., 2012 ([Internet], [cited 2015 Feb 5]; 2012).
    • (2012) J. Aging Res.
    • Marcus, R.L.1    Addison, O.2    Dibble, L.E.3    Foreman, K.B.4    Morrell, G.5    LaStayo, P.6
  • 50
    • 0036114844 scopus 로고    scopus 로고
    • Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
    • (May 15)
    • Petersen, K.F., Oral, E.A., Dufour, S., Befroy, D., Ariyan, C., Yu, C., et al. Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. J. Clin. Invest. 109:10 (2002), 1345–1350 (May 15).
    • (2002) J. Clin. Invest. , vol.109 , Issue.10 , pp. 1345-1350
    • Petersen, K.F.1    Oral, E.A.2    Dufour, S.3    Befroy, D.4    Ariyan, C.5    Yu, C.6
  • 51
    • 0038025371 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in the elderly: possible role in insulin resistance
    • (May 16)
    • Petersen, K.F., Befroy, D., Dufour, S., Dziura, J., Ariyan, C., Rothman, D.L., et al. Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 300:5622 (2003), 1140–1142 (May 16).
    • (2003) Science , vol.300 , Issue.5622 , pp. 1140-1142
    • Petersen, K.F.1    Befroy, D.2    Dufour, S.3    Dziura, J.4    Ariyan, C.5    Rothman, D.L.6
  • 52
    • 1642377274 scopus 로고    scopus 로고
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
    • (Feb 12)
    • Petersen, K.F., Dufour, S., Befroy, D., Garcia, R., Shulman, G.I., Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N. Engl. J. Med. 350:7 (2004), 664–671 (Feb 12).
    • (2004) N. Engl. J. Med. , vol.350 , Issue.7 , pp. 664-671
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Garcia, R.4    Shulman, G.I.5
  • 54
    • 84887168456 scopus 로고    scopus 로고
    • Facts and Figures on Healthy Ageing and Long-term Care [Internet]
    • European Centre for Social Welfare Policy and Research Vienna (Available from:)
    • Rodrigues, R., Huber, M., Lamura, G., Facts and Figures on Healthy Ageing and Long-term Care [Internet]. 2012, European Centre for Social Welfare Policy and Research, Vienna (Available from: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.303.1022&rep=rep1&type=pdf).
    • (2012)
    • Rodrigues, R.1    Huber, M.2    Lamura, G.3
  • 55
    • 66849128458 scopus 로고    scopus 로고
    • Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS (EPIDemiologie de l'OSteoporose) Study
    • (Jun)
    • Rolland, Y., Lauwers-Cances, V., Cristini, C., Abellan van Kan, G., Janssen, I., JE, M., et al. Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS (EPIDemiologie de l'OSteoporose) Study. Am. J. Clin. Nutr. 89:6 (2009), 1895–1900 (Jun).
    • (2009) Am. J. Clin. Nutr. , vol.89 , Issue.6 , pp. 1895-1900
    • Rolland, Y.1    Lauwers-Cances, V.2    Cristini, C.3    Abellan van Kan, G.4    Janssen, I.5    JE, M.6
  • 56
    • 79961088852 scopus 로고    scopus 로고
    • Sarcopenia: origins and clinical relevance
    • (Aug)
    • Rosenberg, I.H., Sarcopenia: origins and clinical relevance. Clin. Geriatr. Med. 27:3 (2011), 337–339 (Aug).
    • (2011) Clin. Geriatr. Med. , vol.27 , Issue.3 , pp. 337-339
    • Rosenberg, I.H.1
  • 57
    • 80052171769 scopus 로고    scopus 로고
    • Predictors of ectopic fat accumulation in liver and pancreas in obese men and women
    • Rossi, A.P., Fantin, F., Zamboni, G.A., Mazzali, G., Rinaldi, C.A., Del Giglio, M., et al. Predictors of ectopic fat accumulation in liver and pancreas in obese men and women. Obesity 19:9 (2011), 1747–1754.
    • (2011) Obesity , vol.19 , Issue.9 , pp. 1747-1754
    • Rossi, A.P.1    Fantin, F.2    Zamboni, G.A.3    Mazzali, G.4    Rinaldi, C.A.5    Del Giglio, M.6
  • 58
    • 4644328086 scopus 로고    scopus 로고
    • Sarcopenic obesity: the confluence of two epidemics
    • (Jun 1)
    • Roubenoff, R., Sarcopenic obesity: the confluence of two epidemics. Obes. Res. 12:6 (2004), 887–888 (Jun 1).
    • (2004) Obes. Res. , vol.12 , Issue.6 , pp. 887-888
    • Roubenoff, R.1
  • 59
    • 84869089985 scopus 로고    scopus 로고
    • TNFα gene knockout differentially affects lipid deposition in liver and skeletal muscle of high-fat-diet mice
    • (Dec)
    • Salles, J., Tardif, N., Landrier, J.-F., Mothe-Satney, I., Guillet, C., Boue-Vaysse, C., et al. TNFα gene knockout differentially affects lipid deposition in liver and skeletal muscle of high-fat-diet mice. J. Nutr. Biochem. 23:12 (2012), 1685–1693 (Dec).
    • (2012) J. Nutr. Biochem. , vol.23 , Issue.12 , pp. 1685-1693
    • Salles, J.1    Tardif, N.2    Landrier, J.-F.3    Mothe-Satney, I.4    Guillet, C.5    Boue-Vaysse, C.6
  • 60
    • 84871067141 scopus 로고    scopus 로고
    • Healthy life expectancy for 187 countries, 1990–2010: a systematic analysis for the Global Burden Disease Study 2010
    • (Dec 15)
    • Salomon, J.A., Wang, H., Freeman, M.K., Vos, T., Flaxman, A.D., Lopez, A.D., et al. Healthy life expectancy for 187 countries, 1990–2010: a systematic analysis for the Global Burden Disease Study 2010. Lancet 380:9859 (2012), 2144–2162 (Dec 15).
    • (2012) Lancet , vol.380 , Issue.9859 , pp. 2144-2162
    • Salomon, J.A.1    Wang, H.2    Freeman, M.K.3    Vos, T.4    Flaxman, A.D.5    Lopez, A.D.6
  • 61
    • 66149129925 scopus 로고    scopus 로고
    • Prevalence of frailty in middle-aged and older community-dwelling Europeans living in 10 countries
    • (Jun)
    • Santos-Eggimann, B., Cuénoud, P., Spagnoli, J., Junod, J., Prevalence of frailty in middle-aged and older community-dwelling Europeans living in 10 countries. J. Gerontol. A Biol. Sci. Med. Sci. 64A:6 (2009), 675–681 (Jun).
    • (2009) J. Gerontol. A Biol. Sci. Med. Sci. , vol.64A , Issue.6 , pp. 675-681
    • Santos-Eggimann, B.1    Cuénoud, P.2    Spagnoli, J.3    Junod, J.4
  • 62
    • 84901608016 scopus 로고    scopus 로고
    • Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults
    • (Jun)
    • Scott, D., Sanders, K.M., Aitken, D., Hayes, A., Ebeling, P.R., Jones, G., Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults. Obesity (Silver Spring) 22:6 (2014), 1568–1574 (Jun).
    • (2014) Obesity (Silver Spring) , vol.22 , Issue.6 , pp. 1568-1574
    • Scott, D.1    Sanders, K.M.2    Aitken, D.3    Hayes, A.4    Ebeling, P.R.5    Jones, G.6
  • 63
    • 84907386500 scopus 로고    scopus 로고
    • Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease
    • (Sep 18)
    • Shulman, G.I., Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease. N. Engl. J. Med. 371:12 (2014), 1131–1141 (Sep 18).
    • (2014) N. Engl. J. Med. , vol.371 , Issue.12 , pp. 1131-1141
    • Shulman, G.I.1
  • 64
    • 84983039225 scopus 로고    scopus 로고
    • Effects of Aging on Muscle Fibre Type and Size
    • Springer ([cited Feb 11])
    • Effects of Aging on Muscle Fibre Type and Size. 2015, Springer ([cited Feb 11]).
    • (2015)
  • 65
    • 67649371151 scopus 로고    scopus 로고
    • Sarcopenic-obesity and cardiovascular disease risk in the elderly
    • (May)
    • Stephen, W.C., Janssen, I., Sarcopenic-obesity and cardiovascular disease risk in the elderly. J. Nutr. Health Aging 13:5 (2009), 460–466 (May).
    • (2009) J. Nutr. Health Aging , vol.13 , Issue.5 , pp. 460-466
    • Stephen, W.C.1    Janssen, I.2
  • 66
    • 39749157727 scopus 로고    scopus 로고
    • Body mass index and cognitive decline in a biracial community population
    • (Jan 29)
    • Sturman, M.T., de Leon, C.F.M., Bienias, J.L., Morris, M.C., Wilson, R.S., Evans, D.A., Body mass index and cognitive decline in a biracial community population. Neurology 70:5 (2008), 360–367 (Jan 29).
    • (2008) Neurology , vol.70 , Issue.5 , pp. 360-367
    • Sturman, M.T.1    de Leon, C.F.M.2    Bienias, J.L.3    Morris, M.C.4    Wilson, R.S.5    Evans, D.A.6
  • 67
    • 77950191531 scopus 로고    scopus 로고
    • Biodemography of human ageing
    • (Mar 25)
    • Vaupel, J.W., Biodemography of human ageing. Nature 464:7288 (2010), 536–542 (Mar 25).
    • (2010) Nature , vol.464 , Issue.7288 , pp. 536-542
    • Vaupel, J.W.1
  • 68
    • 4644335766 scopus 로고    scopus 로고
    • Physical frailty and body composition in obese elderly men and women
    • (Jun 1)
    • Villareal, D.T., Banks, M., Siener, C., Sinacore, D.R., Klein, S., Physical frailty and body composition in obese elderly men and women. Obes. Res. 12:6 (2004), 913–920 (Jun 1).
    • (2004) Obes. Res. , vol.12 , Issue.6 , pp. 913-920
    • Villareal, D.T.1    Banks, M.2    Siener, C.3    Sinacore, D.R.4    Klein, S.5
  • 69
    • 18244399335 scopus 로고    scopus 로고
    • Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons
    • (Mar 1)
    • Visser, M., Goodpaster, B.H., Kritchevsky, S.B., Newman, A.B., Nevitt, M., Rubin, S.M., et al. Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons. J. Gerontol. A Biol. Sci. Med. Sci. 60:3 (2005), 324–333 (Mar 1).
    • (2005) J. Gerontol. A Biol. Sci. Med. Sci. , vol.60 , Issue.3 , pp. 324-333
    • Visser, M.1    Goodpaster, B.H.2    Kritchevsky, S.B.3    Newman, A.B.4    Nevitt, M.5    Rubin, S.M.6
  • 70
    • 33744913541 scopus 로고    scopus 로고
    • Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults
    • (Jun 1)
    • Walston, J., Hadley, E.C., Ferrucci, L., Guralnik, J.M., Newman, A.B., Studenski, S.A., et al. Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J. Am. Geriatr. Soc. 54:6 (2006), 991–1001 (Jun 1).
    • (2006) J. Am. Geriatr. Soc. , vol.54 , Issue.6 , pp. 991-1001
    • Walston, J.1    Hadley, E.C.2    Ferrucci, L.3    Guralnik, J.M.4    Newman, A.B.5    Studenski, S.A.6
  • 71
    • 77953826124 scopus 로고    scopus 로고
    • Structural brain differences and cognitive functioning related to body mass index in older females
    • (Jul 1)
    • Walther, K., Birdsill, A.C., Glisky, E.L., Ryan, L., Structural brain differences and cognitive functioning related to body mass index in older females. Hum. Brain Mapp. 31:7 (2010), 1052–1064 (Jul 1).
    • (2010) Hum. Brain Mapp. , vol.31 , Issue.7 , pp. 1052-1064
    • Walther, K.1    Birdsill, A.C.2    Glisky, E.L.3    Ryan, L.4
  • 72
    • 12744273863 scopus 로고    scopus 로고
    • Midlife cardiovascular risk factors and risk of dementia in late life
    • (Jan 25)
    • Whitmer, R.A., Sidney, S., Selby, J., Johnston, S.C., Yaffe, K., Midlife cardiovascular risk factors and risk of dementia in late life. Neurology 64:2 (2005), 277–281 (Jan 25).
    • (2005) Neurology , vol.64 , Issue.2 , pp. 277-281
    • Whitmer, R.A.1    Sidney, S.2    Selby, J.3    Johnston, S.C.4    Yaffe, K.5
  • 73
    • 20544462061 scopus 로고    scopus 로고
    • Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study
    • (Jun 11)
    • Whitmer, R.A., Gunderson, E.P., Barrett-Connor, E., Quesenberry, C.P., Yaffe, K., Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. BMJ (Trans.) (Jun 11), 330(7504), 2005, 1360.
    • (2005) BMJ , vol.330 , Issue.7504 , pp. 1360
    • Whitmer, R.A.1    Gunderson, E.P.2    Barrett-Connor, E.3    Quesenberry, C.P.4    Yaffe, K.5
  • 75
    • 34147101131 scopus 로고    scopus 로고
    • Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study
    • (Apr 1)
    • Wolf, P., Beiser, A., Elias, M., Au, R., Vasan, R., Seshadri, S., Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study. Curr. Alzheimer Res. 4:2 (2007), 111–116 (Apr 1).
    • (2007) Curr. Alzheimer Res. , vol.4 , Issue.2 , pp. 111-116
    • Wolf, P.1    Beiser, A.2    Elias, M.3    Au, R.4    Vasan, R.5    Seshadri, S.6


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