메뉴 건너뛰기




Volumn 16, Issue 5, 2013, Pages 564-568

Interleukin-6 and obesity: The crosstalk between intestine, pancreas and liver

Author keywords

diabetes; exercise; interleukin 6; muscle; obesity

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INTERLEUKIN 6;

EID: 84883294068     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0b013e32836410e6     Document Type: Review
Times cited : (38)

References (34)
  • 1
    • 79960565557 scopus 로고    scopus 로고
    • Genetic polymorphisms of innate immunity-related inflammatory pathways and their association with factors related to type 2 diabetes
    • Arora P, Garcia-Bailo B, Dastani Z, et al. Genetic polymorphisms of innate immunity-related inflammatory pathways and their association with factors related to type 2 diabetes. BMC Med Genet 2011; 12:95.
    • (2011) BMC Med Genet , vol.12 , pp. 95
    • Arora, P.1    Garcia-Bailo, B.2    Dastani, Z.3
  • 2
    • 84864941472 scopus 로고    scopus 로고
    • Obesity, inflammation and acute myocardial infarction: Expression of leptin, IL-6 and high sensitivity-CRP in Chennai based population
    • Rajendran K, Devarajan N, Ganesan M, Ragunathan M. Obesity, inflammation and acute myocardial infarction: Expression of leptin, IL-6 and high sensitivity-CRP in Chennai based population. Thromb J 2012; 10:13.
    • (2012) Thromb J , vol.10 , pp. 13
    • Rajendran, K.1    Devarajan, N.2    Ganesan, M.3    Ragunathan, M.4
  • 4
    • 84865760308 scopus 로고    scopus 로고
    • The acute-phase response in differentiating sepsis from inflammation in neonates who require abdominal surgery
    • Celik IH, Yilmaz Y, Erdeve O, et al. The acute-phase response in differentiating sepsis from inflammation in neonates who require abdominal surgery. Acta Chirurgica Belgica 2012; 112:292-296.
    • (2012) Acta Chirurgica Belgica , vol.112 , pp. 292-296
    • Celik, I.H.1    Yilmaz, Y.2    Erdeve, O.3
  • 5
    • 81555209757 scopus 로고    scopus 로고
    • The many faces of interleukin-6: The role of IL-6 in inflammation, vasculopathy, and fibrosis in systemic sclerosis
    • Barnes TC, Anderson ME, Moots RJ. The many faces of interleukin-6: The role of IL-6 in inflammation, vasculopathy, and fibrosis in systemic sclerosis. Int J Rheumatol 2011; 2011:721608.
    • (2011) Int J Rheumatol , vol.2011 , pp. 721608
    • Barnes, T.C.1    Anderson, M.E.2    Moots, R.J.3
  • 6
    • 84863219763 scopus 로고    scopus 로고
    • Intrinsic differences in adipocyte precursor cells from different white fat depots
    • Macotela Y, Emanuelli B, Mori MA, et al. Intrinsic differences in adipocyte precursor cells from different white fat depots. Diabetes 2012; 61:691-699.
    • (2012) Diabetes , vol.61 , pp. 691-699
    • Macotela, Y.1    Emanuelli, B.2    Ma, M.3
  • 7
    • 84868138313 scopus 로고    scopus 로고
    • The adipose organ: White-brown adipocyte plasticity and metabolic inflammation
    • Smorlesi A Frontini A Giordano A Cinti S. The adipose organ: White-brown adipocyte plasticity and metabolic inflammation. Obesity Rev 2012; 13 (Suppl 2):83-96.
    • (2012) Obesity Rev , vol.13 , Issue.SUPPL. 2 , pp. 83-96
    • Smorlesi, A.1    Frontini, A.2    Giordano, A.3    Cinti, S.4
  • 8
    • 84857985148 scopus 로고    scopus 로고
    • The cellular and signaling networks linking the immune system and metabolism in disease
    • Osborn O, Olefsky JM. The cellular and signaling networks linking the immune system and metabolism in disease. Nat Med 2012; 18:363-374.
    • (2012) Nat Med , vol.18 , pp. 363-374
    • Osborn, O.1    Olefsky, J.M.2
  • 9
    • 84881138773 scopus 로고    scopus 로고
    • Visceral and subcutaneous adipose tissue from lean women respond differently to lipopolysaccharide-induced alteration of inflammation and glyceroneogenesis
    • Vatier C, Kadiri S, Muscat A, et al. Visceral and subcutaneous adipose tissue from lean women respond differently to lipopolysaccharide-induced alteration of inflammation and glyceroneogenesis. Nutr Diabetes 2012; 2:e51.
    • (2012) Nutr Diabetes , vol.2
    • Vatier, C.1    Kadiri, S.2    Muscat, A.3
  • 10
    • 84863694517 scopus 로고    scopus 로고
    • Mechanisms of inflammatory responses in obese adipose tissue
    • Sun S, Ji Y, Kersten S, Qi L. Mechanisms of inflammatory responses in obese adipose tissue. Annu Rev Nutr 2012; 32:261-286.
    • (2012) Annu Rev Nutr , vol.32 , pp. 261-286
    • Sun, S.1    Ji, Y.2    Kersten, S.3    Qi, L.4
  • 11
    • 84868286394 scopus 로고    scopus 로고
    • Insights into the role of macrophage migration inhibitory factor in obesity and insulin resistance
    • Finucane OM, Reynolds CM, McGillicuddy FC, Roche HM. Insights into the role of macrophage migration inhibitory factor in obesity and insulin resistance. Proc Nutr Soc 2012; 71:622-633.
    • (2012) Proc Nutr Soc , vol.71 , pp. 622-633
    • Finucane, O.M.1    Reynolds, C.M.2    McGillicuddy, F.C.3    Roche, H.M.4
  • 12
    • 84867798919 scopus 로고    scopus 로고
    • Cells of innate and adaptive immunity in type 2 diabetes and obesity]
    • Guzman-Flores JM, Lopez-Briones S. Cells of innate and adaptive immunity in type 2 diabetes and obesity]. Gaceta medica de Mexico 2012; 148:381-389.
    • (2012) Gaceta Medica de Mexico , vol.148 , pp. 381-389
    • Guzman-Flores, J.M.1    Lopez-Briones, S.2
  • 13
    • 84859319452 scopus 로고    scopus 로고
    • Inflammatory concepts of obesity
    • Rocha VZ, Folco EJ. Inflammatory concepts of obesity. Int J Inflamm 2011; 2011:529061.
    • (2011) Int J Inflamm , vol.2011 , pp. 529061
    • Rocha, V.Z.1    Folco, E.J.2
  • 14
    • 84866554319 scopus 로고    scopus 로고
    • Inflammatory markers in pediatric obesity
    • Stolzman S, Bement M. Inflammatory markers in pediatric obesity. ICAN 2012; 297-302.
    • (2012) ICAN , pp. 297-302
    • Stolzman, S.1    Bement, M.2
  • 15
    • 84858638010 scopus 로고    scopus 로고
    • Assess the impact of concentrations of inflammatory markers IL-6, CRP in the presence of albuminuria in patients with type 2 diabetes
    • Czyzewska J, Wasilewska K, Kaminska J, et al. Assess the impact of concentrations of inflammatory markers IL-6, CRP in the presence of albuminuria in patients with type 2 diabetes. Pol Merkur Lekarski 2012; 32:98-102.
    • (2012) Pol Merkur Lekarski , vol.32 , pp. 98-102
    • Czyzewska, J.1    Wasilewska, K.2    Kaminska, J.3
  • 16
    • 77957659561 scopus 로고    scopus 로고
    • The ubiquitous interleukin-6: A time for reappraisal
    • Fisman EZ, Tenenbaum A. The ubiquitous interleukin-6: A time for reappraisal. Cardiovasc Diabetol 2010; 9:62.
    • (2010) Cardiovasc Diabetol , vol.9 , pp. 62
    • Fisman, E.Z.1    Tenenbaum, A.2
  • 18
    • 79956222223 scopus 로고    scopus 로고
    • The interleukin-6 and noradrenaline mediated inflammation-stress feedback mechanism is dysregulated in metabolic syndrome: Effect of exercise
    • Martin-Cordero L, Garcia JJ, Hinchado MD, Ortega E. The interleukin-6 and noradrenaline mediated inflammation-stress feedback mechanism is dysregulated in metabolic syndrome: Effect of exercise. Cardiovasc Diabetol 2011; 10:42.
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 42
    • Martin-Cordero, L.1    Garcia, J.J.2    Hinchado, M.D.3    Ortega, E.4
  • 19
    • 78651379305 scopus 로고    scopus 로고
    • Muscles and their myokines
    • Pedersen BK. Muscles and their myokines. J Exp Biol 2011; 214 (Pt 2):337-346.
    • (2011) J Exp Biol , vol.214 , Issue.PART 2 , pp. 337-346
    • Pedersen, B.K.1
  • 20
    • 23044448763 scopus 로고    scopus 로고
    • Muscle-derived interleukin-6: A possible link between skeletal muscle, adipose tissue, liver, and brain
    • Pedersen BK, Febbraio M. Muscle-derived interleukin-6: A possible link between skeletal muscle, adipose tissue, liver, and brain. Brain Behav Immun 2005; 19:371-376.
    • (2005) Brain Behav Immun , vol.19 , pp. 371-376
    • Pedersen, B.K.1    Febbraio, M.2
  • 21
    • 79952175492 scopus 로고    scopus 로고
    • Blocking the IL-6-STAT3 signaling pathway: Potential liver cancer therapy
    • Liu Y, Lin J. Blocking the IL-6-STAT3 signaling pathway: Potential liver cancer therapy. Future Oncol 2011; 7:161-164.
    • (2011) Future Oncol , vol.7 , pp. 161-164
    • Liu, Y.1    Lin, J.2
  • 22
    • 84868199305 scopus 로고    scopus 로고
    • Interleukin-6 mediates exerciseinduced increase in insulin sensitivity in mice
    • Benrick A, Wallenius V, Asterholm IW. Interleukin-6 mediates exerciseinduced increase in insulin sensitivity in mice. Exp Physiol 2012; 97:1224-1235.
    • (2012) Exp Physiol , vol.97 , pp. 1224-1235
    • Benrick, A.1    Wallenius, V.2    Asterholm, I.W.3
  • 23
    • 84883291926 scopus 로고    scopus 로고
    • Changes in insulin resistance and HbA1c are related to exercise-mediated changes in body composition in older adults with Type 2 diabetes interim outcomes from the GREAT2DO trial
    • Epub ahead of print
    • Mavros Y, Kay S, Anderberg KA, et al. Changes in insulin resistance and HbA1c are related to exercise-mediated changes in body composition in older adults with Type 2 diabetes interim outcomes from the GREAT2DO trial. Diabetes Care 2013. [Epub ahead of print]
    • (2013) Diabetes Care
    • Mavros, Y.1    Kay, S.2    Anderberg, K.A.3
  • 24
    • 55949119252 scopus 로고    scopus 로고
    • Muscle as an endocrine organ: Focus on musclederived interleukin-6
    • Pedersen BK, Febbraio M. Muscle as an endocrine organ: Focus on musclederived interleukin-6. Physiol Rev 2008; 88:.
    • (2008) Physiol Rev , vol.88
    • Pedersen, B.K.1    Febbraio, M.2
  • 25
    • 84878908501 scopus 로고    scopus 로고
    • Increase in interleukin-6 immediately after wheelchair basketball games in persons with spinal cord injury: Preliminary report
    • Kinoshita T, Nakamura T, Umemoto Y, et al. Increase in interleukin-6 immediately after wheelchair basketball games in persons with spinal cord injury: Preliminary report. Spinal Cord 2013; 51:508-510.
    • (2013) Spinal Cord , vol.51 , pp. 508-510
    • Kinoshita, T.1    Nakamura, T.2    Umemoto, Y.3
  • 26
    • 34147159710 scopus 로고    scopus 로고
    • Gp130 receptor ligands as potential therapeutic targets for obesity
    • Febbraio MA. Gp130 receptor ligands as potential therapeutic targets for obesity. J Clin Investig 2007; 117:841-849.
    • (2007) J Clin Investig , vol.117 , pp. 841-849
    • Febbraio, M.A.1
  • 27
    • 81255157471 scopus 로고    scopus 로고
    • Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
    • Ellingsgaard H, Hauselmann I, Schuler B, et al. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med 2011; 17:1481-1489.
    • (2011) Nat Med , vol.17 , pp. 1481-1489
    • Ellingsgaard, H.1    Hauselmann, I.2    Schuler, B.3
  • 28
    • 84864401274 scopus 로고    scopus 로고
    • Alpha-cell role in beta-cell generation and regeneration
    • Habener JF, Stanojevic V. Alpha-cell role in beta-cell generation and regeneration. Islets 2012; 4:188-198.
    • (2012) Islets , vol.4 , pp. 188-198
    • Habener, J.F.1    Stanojevic, V.2
  • 29
    • 77951611220 scopus 로고    scopus 로고
    • Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
    • Thorel F, Nepote V, Avril I, et al. Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss. Nature 2010; 464:1149-1154.
    • (2010) Nature , vol.464 , pp. 1149-1154
    • Thorel, F.1    Nepote, V.2    Avril, I.3
  • 30
    • 84874045511 scopus 로고    scopus 로고
    • The origins and drivers of insulin resistance
    • Johnson AM, Olefsky JM. The origins and drivers of insulin resistance. Cell 2013; 152:673-684.
    • (2013) Cell , vol.152 , pp. 673-684
    • Johnson, A.M.1    Olefsky, J.M.2
  • 32
    • 77951611220 scopus 로고    scopus 로고
    • Conversion of adult pancreatic a-cells to b-cells after extreme b-cell loss
    • Thorel F, Né pote V, Avril A. Conversion of adult pancreatic a-cells to b-cells after extreme b-cell loss. Nature 2010; 464:1149-1154.
    • (2010) Nature , vol.464 , pp. 1149-1154
    • Thorel, F.1    Né Pote, V.2    Avril, A.3
  • 33
    • 84866278132 scopus 로고    scopus 로고
    • Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic beta-cell line and mouse islets
    • da Silva Krause M, Bittencourt A, Homem de Bittencourt PI Jr, et al. Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic beta-cell line and mouse islets. J Endocrinol 2012; 214:301-311.
    • (2012) J Endocrinol , vol.214 , pp. 301-311
    • Da Silva Krause, M.1    Bittencourt, A.2    Homem De Bittencourt Jr., P.I.3
  • 34
    • 84876486772 scopus 로고    scopus 로고
    • Role of endogenous IL-6 in the neonatal expansion and functionality of Wistar rat pancreatic alpha cells
    • doi:10.1007/s00125-013-2862-8
    • Fernandez-Millan E, de Toro-Martin J, Lizarraga-Mollinedo E, et al. Role of endogenous IL-6 in the neonatal expansion and functionality of Wistar rat pancreatic alpha cells. Diabetologia 2013. doi:10.1007/s00125-013-2862-8.
    • (2013) Diabetologia
    • Fernandez-Millan, E.1    De Toro-Martin, J.2    Lizarraga-Mollinedo, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.