-
1
-
-
84921283939
-
Keratins in health and disease
-
Toivola, D.M. et al. (2015) Keratins in health and disease. Curr. Opin. Cell Biol., 32, 73-81.
-
(2015)
Curr. Opin. Cell Biol.
, vol.32
, pp. 73-81
-
-
Toivola, D.M.1
-
2
-
-
84920971108
-
Regulation of keratin network organization
-
Loschke, F. et al. (2015) Regulation of keratin network organization. Curr. Opin. Cell Biol., 32, 56-64.
-
(2015)
Curr. Opin. Cell Biol.
, vol.32
, pp. 56-64
-
-
Loschke, F.1
-
3
-
-
0038446762
-
Keratin 20 helps maintain intermediate filament organization in intestinal epithelia
-
Zhou, Q. et al. (2003) Keratin 20 helps maintain intermediate filament organization in intestinal epithelia. Mol. Biol. Cell, 14, 2959-2971.
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 2959-2971
-
-
Zhou, Q.1
-
4
-
-
75149145548
-
Intermediate filaments take the heat as stress proteins
-
Toivola, D.M. et al. (2010) Intermediate filaments take the heat as stress proteins. Trends Cell Biol., 20, 79-91.
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 79-91
-
-
Toivola, D.M.1
-
5
-
-
68849111162
-
Toward unraveling the complexity of simple epithelial keratins in human disease
-
Omary, M.B. et al. (2009) Toward unraveling the complexity of simple epithelial keratins in human disease. J. Clin. Invest., 119, 1794-1805.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1794-1805
-
-
Omary, M.B.1
-
6
-
-
84873731727
-
The expanding significance of keratin intermediate filaments in normal and diseased epithelia
-
Pan, X. et al. (2013) The expanding significance of keratin intermediate filaments in normal and diseased epithelia. Curr. Opin. Cell Biol., 25, 47-56.
-
(2013)
Curr. Opin. Cell Biol.
, vol.25
, pp. 47-56
-
-
Pan, X.1
-
7
-
-
66749174066
-
Cytokines as genetic modifiers in K5-/-mice and in human epidermolysis bullosa simplex
-
Roth, W. et al. (2009) Cytokines as genetic modifiers in K5-/-mice and in human epidermolysis bullosa simplex. Hum. Mutat., 30, 832-841.
-
(2009)
Hum. Mutat.
, vol.30
, pp. 832-841
-
-
Roth, W.1
-
8
-
-
84873562874
-
Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18
-
Roth, W. et al. (2012) Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18. J. Cell Sci., 125(Pt 22), 5269-5279.
-
(2012)
J. Cell Sci.
, vol.125
, pp. 5269-5279
-
-
Roth, W.1
-
9
-
-
2942576061
-
Human keratin 8 mutations that disturb filament assembly observed in inflammatory bowel disease patients
-
Owens, D.W. et al. (2004) Human keratin 8 mutations that disturb filament assembly observed in inflammatory bowel disease patients. J. Cell Sci., 117(Pt 10), 1989-1999.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 1989-1999
-
-
Owens, D.W.1
-
10
-
-
7944229258
-
Keratin mutations and intestinal pathology
-
Owens, D.W. et al. (2004) Keratin mutations and intestinal pathology. J. Pathol., 204, 377-385.
-
(2004)
J. Pathol.
, vol.204
, pp. 377-385
-
-
Owens, D.W.1
-
11
-
-
34447256176
-
Analysis of keratin polypeptides 8 and 19 variants in inflammatory bowel disease
-
Tao, G.Z. et al. (2007) Analysis of keratin polypeptides 8 and 19 variants in inflammatory bowel disease. Clin. Gastroenterol. Hepatol., 5, 857-864.
-
(2007)
Clin. Gastroenterol. Hepatol.
, vol.5
, pp. 857-864
-
-
Tao, G.Z.1
-
12
-
-
19444375279
-
Keratin-8-deficient mice develop chronic spontaneous Th2 colitis amenable to antibiotic treatment
-
Habtezion, A. et al. (2005) Keratin-8-deficient mice develop chronic spontaneous Th2 colitis amenable to antibiotic treatment. J. Cell Sci., 118(Pt 9), 1971-1980.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 1971-1980
-
-
Habtezion, A.1
-
13
-
-
77956652125
-
Animal models of IBD: linkage to human disease
-
Mizoguchi, A. et al. (2010) Animal models of IBD: linkage to human disease. Curr. Opin. Pharmacol., 10, 578-587.
-
(2010)
Curr. Opin. Pharmacol.
, vol.10
, pp. 578-587
-
-
Mizoguchi, A.1
-
14
-
-
78649368287
-
Inflammatory bowel disease as a risk factor for colorectal cancer
-
Lukas, M. (2010) Inflammatory bowel disease as a risk factor for colorectal cancer. Dig. Dis., 28, 619-624.
-
(2010)
Dig. Dis.
, vol.28
, pp. 619-624
-
-
Lukas, M.1
-
15
-
-
79952129489
-
Absence of keratin 8 confers a paradoxical microflora-dependent resistance to apoptosis in the colon
-
Habtezion, A. et al. (2011) Absence of keratin 8 confers a paradoxical microflora-dependent resistance to apoptosis in the colon. Proc. Natl. Acad. Sci. USA, 108, 1445-1450.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 1445-1450
-
-
Habtezion, A.1
-
16
-
-
33749347347
-
Ketogenic HMGCS2 Is a c-Myc target gene expressed in differentiated cells of human colonic epithelium and down-regulated in colon cancer
-
Camarero, N. et al. (2006) Ketogenic HMGCS2 Is a c-Myc target gene expressed in differentiated cells of human colonic epithelium and down-regulated in colon cancer. Mol. Cancer Res., 4, 645-653.
-
(2006)
Mol. Cancer Res.
, vol.4
, pp. 645-653
-
-
Camarero, N.1
-
17
-
-
84930885868
-
Keratin 8 absence down-regulates colonocyte HMGCS2 and modulates colonic ketogenesis and energy metabolism
-
Helenius, T.O. et al. (2015) Keratin 8 absence down-regulates colonocyte HMGCS2 and modulates colonic ketogenesis and energy metabolism. Mol. Biol. Cell, 26, 2298-2310.
-
(2015)
Mol. Biol. Cell
, vol.26
, pp. 2298-2310
-
-
Helenius, T.O.1
-
18
-
-
1642348652
-
Keratins modulate colonocyte electrolyte transport via protein mistargeting
-
Toivola, D.M. et al. (2004) Keratins modulate colonocyte electrolyte transport via protein mistargeting. J. Cell Biol., 164, 911-921.
-
(2004)
J. Cell Biol.
, vol.164
, pp. 911-921
-
-
Toivola, D.M.1
-
19
-
-
84930657450
-
The amount of keratins matters for stress protection of the colonic epithelium
-
Asghar, M.N. et al. (2015) The amount of keratins matters for stress protection of the colonic epithelium. PLoS One, 10, e0127436.
-
(2015)
PLoS One
, vol.10
-
-
Asghar, M.N.1
-
20
-
-
78649757427
-
Interleukin-22: a cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection
-
Witte, E. et al. (2010) Interleukin-22: a cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection. Cytokine Growth Factor Rev., 21, 365-379.
-
(2010)
Cytokine Growth Factor Rev.
, vol.21
, pp. 365-379
-
-
Witte, E.1
-
21
-
-
84939571923
-
Deciphering the crosstalk among IL-1 and IL-10 family cytokines in intestinal immunity
-
Manzanillo, P. et al. (2015) Deciphering the crosstalk among IL-1 and IL-10 family cytokines in intestinal immunity. Trends Immunol., 36, 471-478.
-
(2015)
Trends Immunol.
, vol.36
, pp. 471-478
-
-
Manzanillo, P.1
-
22
-
-
84879571464
-
Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
-
Kirchberger, S. et al. (2013) Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model. J. Exp. Med., 210, 917-931.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 917-931
-
-
Kirchberger, S.1
-
23
-
-
79955030498
-
Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
-
Sonnenberg, G.F. et al. (2011) Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. Nat. Immunol., 12, 383-390.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 383-390
-
-
Sonnenberg, G.F.1
-
24
-
-
67650474246
-
STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
-
Pickert, G. et al. (2009) STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing. J. Exp. Med., 206, 1465-1472.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1465-1472
-
-
Pickert, G.1
-
25
-
-
84873253765
-
IL-22 is related to development of human colon cancer by activation of STAT3
-
Jiang, R. et al. (2013) IL-22 is related to development of human colon cancer by activation of STAT3. BMC Cancer, 13, 59.
-
(2013)
BMC Cancer
, vol.13
, pp. 59
-
-
Jiang, R.1
-
26
-
-
84900459331
-
IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L
-
Kryczek, I. et al. (2014) IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L. Immunity, 40, 772-784.
-
(2014)
Immunity
, vol.40
, pp. 772-784
-
-
Kryczek, I.1
-
27
-
-
84868615556
-
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
-
Huber, S. et al. (2012) IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature, 491, 259-263.
-
(2012)
Nature
, vol.491
, pp. 259-263
-
-
Huber, S.1
-
28
-
-
84890905720
-
Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid
-
Martin, J.C. et al. (2014) Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunol., 7, 101-113.
-
(2014)
Mucosal Immunol.
, vol.7
, pp. 101-113
-
-
Martin, J.C.1
-
29
-
-
77950362382
-
The inflammasomes
-
Schroder, K. et al. (2010) The inflammasomes. Cell, 140, 821-832.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
-
30
-
-
84923107393
-
Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection
-
Muñoz, M. et al. (2015) Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection. Immunity, 42, 321-331.
-
(2015)
Immunity
, vol.42
, pp. 321-331
-
-
Muñoz, M.1
-
31
-
-
34548162712
-
An inducible mouse model of colon carcino-genesis for the analysis of sporadic and inflammation-driven tumor progression
-
Neufert, C. et al. (2007) An inducible mouse model of colon carcino-genesis for the analysis of sporadic and inflammation-driven tumor progression. Nat. Protoc., 2, 1998-2004.
-
(2007)
Nat. Protoc.
, vol.2
, pp. 1998-2004
-
-
Neufert, C.1
-
32
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell, S.M. et al. (1992) APC mutations occur early during colorectal tumorigenesis. Nature, 359, 235-237.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
-
33
-
-
0028567875
-
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
-
Fodde, R. et al. (1994) A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc. Natl. Acad. Sci. USA, 91, 8969-8973.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8969-8973
-
-
Fodde, R.1
-
34
-
-
0028607055
-
Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice
-
Baribault, H. et al. (1994) Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. Genes Dev., 8, 2964-2973.
-
(1994)
Genes Dev.
, vol.8
, pp. 2964-2973
-
-
Baribault, H.1
-
35
-
-
84887010498
-
Genome engineering using the CRISPR-Cas9 system
-
Ran, F.A. et al. (2013) Genome engineering using the CRISPR-Cas9 system. Nat. Protoc., 8, 2281-2308.
-
(2013)
Nat. Protoc.
, vol.8
, pp. 2281-2308
-
-
Ran, F.A.1
-
36
-
-
84923229919
-
An efficient genotyping method for genome-modified animals and human cells generated with CRISPR/Cas9 system
-
Zhu, X. et al. (2014) An efficient genotyping method for genome-modified animals and human cells generated with CRISPR/Cas9 system. Sci. Rep., 4, 6420.
-
(2014)
Sci. Rep.
, vol.4
, pp. 6420
-
-
Zhu, X.1
-
37
-
-
34347262689
-
Chemically induced mouse models of intestinal inflammation
-
Wirtz, S. et al. (2007) Chemically induced mouse models of intestinal inflammation. Nat. Protoc., 2, 541-546.
-
(2007)
Nat. Protoc.
, vol.2
, pp. 541-546
-
-
Wirtz, S.1
-
38
-
-
27944442806
-
Dextran sodium sulfate strongly promotes colorectal carcinogenesis in Apc(Min/+) mice: inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms
-
Tanaka, T. et al. (2006) Dextran sodium sulfate strongly promotes colorectal carcinogenesis in Apc(Min/+) mice: inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms. Int. J. Cancer, 118, 25-34.
-
(2006)
Int. J. Cancer
, vol.118
, pp. 25-34
-
-
Tanaka, T.1
-
39
-
-
78649835822
-
A method for serial tissue processing and parallel analysis of aberrant crypt morphology, mucin depletion, and Beta-catenin staining in an experimental model of colon carcinogen-esis
-
McGinley, J.N. et al. (2010) A method for serial tissue processing and parallel analysis of aberrant crypt morphology, mucin depletion, and Beta-catenin staining in an experimental model of colon carcinogen-esis. Biol. Proced. Online, 12, 9032.
-
(2010)
Biol. Proced. Online
, vol.12
, pp. 9032
-
-
McGinley, J.N.1
-
40
-
-
0027227464
-
Mid-gestational lethality in mice lacking keratin 8
-
Baribault, H. et al. (1993) Mid-gestational lethality in mice lacking keratin 8. Genes Dev., 7, 1191-1202.
-
(1993)
Genes Dev.
, vol.7
, pp. 1191-1202
-
-
Baribault, H.1
-
41
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan, D. et al. (2011) Hallmarks of cancer: the next generation. Cell, 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
-
42
-
-
22144459760
-
Aberrant crypt foci: detection, gene abnormalities, and clinical usefulness
-
Takayama, T. et al. (2005) Aberrant crypt foci: detection, gene abnormalities, and clinical usefulness. Clin. Gastroenterol. Hepatol., 3(7 Suppl 1), S42-S45.
-
(2005)
Clin. Gastroenterol. Hepatol.
, vol.3
, pp. S42-S45
-
-
Takayama, T.1
-
43
-
-
34247524128
-
Aberrant crypt foci: what we know and what we need to know
-
Gupta, A.K. et al. (2007) Aberrant crypt foci: what we know and what we need to know. Clin. Gastroenterol. Hepatol., 5, 526-533.
-
(2007)
Clin. Gastroenterol. Hepatol.
, vol.5
, pp. 526-533
-
-
Gupta, A.K.1
-
44
-
-
79956065172
-
The min mouse on FVB background: susceptibility to spontaneous and carcinogen-induced intestinal tumourigenesis
-
Svendsen, C. et al. (2011) The min mouse on FVB background: susceptibility to spontaneous and carcinogen-induced intestinal tumourigenesis. Anticancer Res., 31, 785-788.
-
(2011)
Anticancer Res.
, vol.31
, pp. 785-788
-
-
Svendsen, C.1
-
45
-
-
84911206728
-
Higher activity of the inducible nitric oxide synthase contributes to very early onset inflammatory bowel disease
-
Dhillon, S.S. et al. (2014) Higher activity of the inducible nitric oxide synthase contributes to very early onset inflammatory bowel disease. Clin. Transl. Gastroenterol., 5, e46.
-
(2014)
Clin. Transl. Gastroenterol.
, vol.5
, pp. e46
-
-
Dhillon, S.S.1
-
46
-
-
0031902251
-
Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease
-
Singer, I.I. et al. (1998) Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease. Gastroenterology, 115, 297-306.
-
(1998)
Gastroenterology
, vol.115
, pp. 297-306
-
-
Singer, I.I.1
-
47
-
-
0033911401
-
Families of retinoid dehydrogenases regulating vita-min A function: production of visual pigment and retinoic acid
-
Duester, G. (2000) Families of retinoid dehydrogenases regulating vita-min A function: production of visual pigment and retinoic acid. Eur. J. Biochem., 267, 4315-4324.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 4315-4324
-
-
Duester, G.1
-
48
-
-
44149099717
-
The human keratins: biology and pathology
-
Moll, R. et al. (2008) The human keratins: biology and pathology. Histochem. Cell Biol., 129, 705-733.
-
(2008)
Histochem. Cell Biol.
, vol.129
, pp. 705-733
-
-
Moll, R.1
-
49
-
-
78651397689
-
Keratins in health and cancer: more than mere epithelial cell markers
-
Karantza, V. (2011) Keratins in health and cancer: more than mere epithelial cell markers. Oncogene, 30, 127-138.
-
(2011)
Oncogene
, vol.30
, pp. 127-138
-
-
Karantza, V.1
-
50
-
-
33748917425
-
Cytokeratin profiles identify diagnostic signatures in colorectal cancer using multiplex analysis of tissue microar-rays
-
Knösel, T. et al. (2006) Cytokeratin profiles identify diagnostic signatures in colorectal cancer using multiplex analysis of tissue microar-rays. Cell. Oncol., 28, 167-175.
-
(2006)
Cell. Oncol.
, vol.28
, pp. 167-175
-
-
Knösel, T.1
-
51
-
-
84929583628
-
Molecular Mechanisms of Colorectal Carcinogenesis
-
Springer, New York
-
Roper, J., Hung, K. E. (2013) Molecular Mechanisms of Colorectal Carcinogenesis. Springer, New York.
-
(2013)
-
-
Roper, J.1
Hung, K.E.2
-
52
-
-
84880731344
-
Unique gene expression and MR T2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease
-
Breynaert, C. et al. (2013) Unique gene expression and MR T2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease. PLoS One, 8, e68876.
-
(2013)
PLoS One
, vol.8
-
-
Breynaert, C.1
-
53
-
-
85019424343
-
Inflammation decreases keratin level in ulcerative colitis; inadequate restoration associates with increased risk of colitis-associated cancer
-
Corfe, B.M. et al. (2015) Inflammation decreases keratin level in ulcerative colitis; inadequate restoration associates with increased risk of colitis-associated cancer. BMJ Open Gastroenterol., 2, e000024.
-
(2015)
BMJ Open Gastroenterol.
, vol.2
-
-
Corfe, B.M.1
-
54
-
-
24144477540
-
Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibro-blasts
-
Andoh, A. et al. (2005) Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibro-blasts. Gastroenterology, 129, 969-984.
-
(2005)
Gastroenterology
, vol.129
, pp. 969-984
-
-
Andoh, A.1
-
55
-
-
84943663898
-
Diverse roles of STING-dependent signaling on the development of cancer
-
Ahn, J. et al. (2015) Diverse roles of STING-dependent signaling on the development of cancer. Oncogene, 34, 5302-5308.
-
(2015)
Oncogene
, vol.34
, pp. 5302-5308
-
-
Ahn, J.1
-
56
-
-
84941618385
-
Adoptive transfer of regulatory T cells promotes intestinal tumorigenesis and is associated with decreased NK cells and IL-22 binding protein
-
Janakiram, N.B. et al. (2015) Adoptive transfer of regulatory T cells promotes intestinal tumorigenesis and is associated with decreased NK cells and IL-22 binding protein. Mol. Carcinog., 54, 986-998.
-
(2015)
Mol. Carcinog.
, vol.54
, pp. 986-998
-
-
Janakiram, N.B.1
-
57
-
-
84924617839
-
Vimentin regulates activation of the NLRP3 inflammasome
-
dos Santos, G. et al. (2015) Vimentin regulates activation of the NLRP3 inflammasome. Nat. Commun., 6, 6574.
-
(2015)
Nat. Commun.
, vol.6
, pp. 6574
-
-
dos Santos, G.1
|