The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis

PLoS Biology

Volumn 14, Issue 7, 2016, Pages

  Seo, Jae Ho ^a   Rivadeneira, Dayana B ^a   Caino, M Cecilia ^a   Chae, Young Chan ^a   Speicher, David W ^a   Tang, Hsin Yao ^a   Vaira, Valentina ^b,c   Bosari, Silvano ^b,c   Palleschi, Alessandro ^b   Rampini, Paolo ^b   Kossenkov, Andrew V ^a   Languino, Lucia R ^a,d   Altieri, Dario C ^a  

^a WISTAR INSTITUTE   (United States)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOCHONDRIAL UNFOLDASE PEPTIDASE COMPLEX CLPXP; PEPTIDASE; REACTIVE OXYGEN METABOLITE; SUCCINATE DEHYDROGENASE; SURVIVIN; UNCLASSIFIED DRUG; BIRC5 PROTEIN, HUMAN; CLPP PROTEIN, HUMAN; CLPX PROTEIN, HUMAN; ENDOPEPTIDASE CLP; INHIBITOR OF APOPTOSIS PROTEIN; MITOCHONDRIAL PROTEIN; PROTEIN SUBUNIT; SDHD PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; BIOACCUMULATION; BIOENERGY; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; METASTASIS POTENTIAL; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEIN TARGETING; PROTEIN UNFOLDING; PROTEOMICS; REGULATORY MECHANISM; TUMOR INVASION; ADULT; AGED; ANIMAL; ENERGY METABOLISM; FEMALE; GENETICS; KNOCKOUT MOUSE; MALE; METABOLISM; METASTASIS; MIDDLE AGED; MITOCHONDRION; NEOPLASM; NONOBESE DIABETIC MOUSE; PATHOLOGY; PROCEDURES; PROTEIN SUBUNIT; RNA INTERFERENCE; SCID MOUSE; TUMOR CELL LINE; VERY ELDERLY; XENOGRAFT;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CELL LINE, TUMOR; ENDOPEPTIDASE CLP; ENERGY METABOLISM; FEMALE; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MALE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; MIDDLE AGED; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NEOPLASM METASTASIS; NEOPLASMS; PROTEIN SUBUNITS; PROTEOMICS; RNA INTERFERENCE; SUCCINATE DEHYDROGENASE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84982845343     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1002507     Document Type: Article

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