Rab5 is required in metastatic cancer cells for caveolin-1-enhanced Rac1 activation, migration and invasion

Journal of Cell Science

Volumn 127, Issue 11, 2014, Pages 2401-2406

  Díaz, Jorge ^a,b   Mendoza, Pablo ^a   Ortiz, Rina ^b   Díaz, Natalia ^b   Leyton, Lisette ^b   Stupack, Dwayne ^c   Quest, Andrew F G ^b   Torres, Vicente A ^a,b  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Caveolin 1; Metastatic cell migration; P85 ; Rab5; Rac1; Small GTPases

Indexed keywords

4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; CAVEOLIN 1; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATE; PROTEIN P85; PROTEIN P85ALPHA; RAB PROTEIN; RAC1 PROTEIN; SHORT HAIRPIN RNA; TIAM1 PROTEIN; UNCLASSIFIED DRUG; AMINOQUINOLINE DERIVATIVE; DNA BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PIK3R1 PROTEIN, HUMAN; PYRIMIDINE DERIVATIVE; SLC2A4RG PROTEIN, HUMAN; SMALL INTERFERING RNA; TIAM1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER CELL; CELL INVASION; CELL MIGRATION; COLON ADENOCARCINOMA; CONTROLLED STUDY; DOWN REGULATION; ENDOSOME; GENE TARGETING; HUMAN; HUMAN CELL; MELANOMA; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL MOTION; DRUG EFFECTS; EXPERIMENTAL MELANOMA; GENETICS; HT 29 CELL LINE; METABOLISM; SIGNAL TRANSDUCTION; TUMOR INVASION;

AMINOQUINOLINES; ANIMALS; CAVEOLIN 1; CELL MOVEMENT; DNA-BINDING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HT29 CELLS; HUMANS; MELANOMA, EXPERIMENTAL; MICE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PHOSPHATIDYLINOSITOL 3-KINASES; PYRIMIDINES; RAB5 GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84901806788     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.141689     Document Type: Article

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