CO2-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture

eLife

Volumn 5, Issue JULY, 2016, Pages

  Forsberg, David ^a,b   Horn, Zachi ^a,b   Tserga, Evangelia ^a,b   Smedler, Erik ^a   Silberberg, Gilad ^a   Shvarev, Yuri ^a,b   Kaila, Kai ^c   Uhlén, Per ^a   Herlenius, Eric ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CARBON DIOXIDE; CONNEXIN 26; CONNEXIN 32; CONNEXIN 43; MICROTUBULE ASSOCIATED PROTEIN 2; NEUROKININ 1 RECEPTOR; POTASSIUM CHLORIDE COTRANSPORTER 2; PROSTAGLANDIN E RECEPTOR 3; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; VESICULAR GLUTAMATE TRANSPORTER 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL CULTURE; BRAIN ELECTROPHYSIOLOGY; BREATHING PATTERN; BREATHING RATE; CARBON DIOXIDE BLOOD LEVEL; CHEMOSENSITIVITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPERCAPNIA; IMMUNOHISTOCHEMISTRY; INSPIRATORY CAPACITY; MOTOR ACTIVITY; MOUSE; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL NETWORK; NONHUMAN; PLETHYSMOGRAPHY; PROPIDIUM IODIDE ASSAY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATION CONTROL; VIRAL GENE DELIVERY SYSTEM; WHOLE CELL PATCH CLAMP; ACTION POTENTIAL; ANIMAL; BRAIN STEM; BREATHING; DRUG EFFECTS; METABOLISM; OPTOGENETICS; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY;

ACTION POTENTIALS; ANIMALS; BRAIN STEM; CARBON DIOXIDE; DINOPROSTONE; MICE; NERVE NET; OPTOGENETICS; ORGAN CULTURE TECHNIQUES; RESPIRATION;

EID: 84982822993     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.14170     Document Type: Article

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